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The map label for this gene is gsiC [H]

Identifier: 158424618

GI number: 158424618

Start: 3422642

End: 3423562

Strand: Reverse

Name: gsiC [H]

Synonym: AZC_2994

Alternate gene names: 158424618

Gene position: 3423562-3422642 (Counterclockwise)

Preceding gene: 158424619

Following gene: 158424617

Centisome position: 63.76

GC content: 64.6

Gene sequence:

>921_bases
ATGCTGGAATATCTCGTCAAGCGCCTCCTGGGCATCATTCCGGTGATCTTCGCGATCTCCGTGGTGGTGTTCGCCTTCGT
CCATCTGCTGCCGGGCGACCCCGCGCGTCTCGTTGCGGGCGTGGATGCCTCGCCGGAGGACGTGGCGGCGGTGCGCCAGT
CTCTCGGCCTCGAGGGGCCGCTGTGGCAGCAGTATGTGCGCTTCGCGGGCAATGCGTTGCAGGGTGATTTCGGCATCTCG
CTCAAGACCCGTCGCCCGGTCATCACGGAGATCGGCGAGCGGCTCATGCCCACCGTCTGGCTCACCGTCTTCGCGATGAT
CTGGGCCACCATCTTCGGCCTGCTCATCGGCGTGCTTTCGGCCGTGAAGCGCGGCCGCTGGCAGGACTATGGCGGCATGA
TCATCGCCGTCTCGGGCATTTCCTTCCCCTCCTTCTGGCTCGGCCTGCTGCTGATCGACCTCTTCTCCGTGCGCCTCGGC
TGGCTGCCAACCGGCGGCTACGGCACCTGGGCGCATTTCGTGATGCCGTCCTTCACGCTCGGTCTTGGCGTTGCGGCGGT
GATGGCCCGCTTCACCCGTTCCGCCTTCGTGGAGATCGCCCGCGAGGATTATGTGCGCACCGCCAGAGCCAAGGGCGTGC
CCGAGAAGACCGTCATCTGGAAGCACACGCTGCGCAACGCGCTGGTGCCGGTCATCACCATGACGGGCCTGCAATTCGGC
TTCCTGCTGGGCGGCTCCATCGTGGTGGAGACGGTGTTCAGCTGGCCCGGCCTCGGGCGCCTTCTCGTCGATAGCGTCTC
CTATCGCGACTATCCGGTGATCCAGGCGGAGATTTTGCTGTTCTCGCTGGAGTTCATCTTCATCAACCTCGCGGTGGACG
TGCTCTACGCCTTCGCCAATCCGGAGATCCGCTACAAATGA

Upstream 100 bases:

>100_bases
GGGCGGTGCTCCTCCCGGCTGTCCCCCGCCGGCCGGGAGGAGCGCACATCAGCCGCCGGGCGCCCGCGCCCCGCCCGTTT
CGCGTCCGCCGGATGCCGCC

Downstream 100 bases:

>100_bases
GCGCCGCGACCTCCGCCTCCGCTTCTCCCGCCGCGCCGCGCGCCATGCGCACGCCGGTCAGCGAGTTCTGGCGCCGCTTC
CGCAAGCAGAAGGTGGCGCT

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLEYLVKRLLGIIPVIFAISVVVFAFVHLLPGDPARLVAGVDASPEDVAAVRQSLGLEGPLWQQYVRFAGNALQGDFGIS
LKTRRPVITEIGERLMPTVWLTVFAMIWATIFGLLIGVLSAVKRGRWQDYGGMIIAVSGISFPSFWLGLLLIDLFSVRLG
WLPTGGYGTWAHFVMPSFTLGLGVAAVMARFTRSAFVEIAREDYVRTARAKGVPEKTVIWKHTLRNALVPVITMTGLQFG
FLLGGSIVVETVFSWPGLGRLLVDSVSYRDYPVIQAEILLFSLEFIFINLAVDVLYAFANPEIRYK

Sequences:

>Translated_306_residues
MLEYLVKRLLGIIPVIFAISVVVFAFVHLLPGDPARLVAGVDASPEDVAAVRQSLGLEGPLWQQYVRFAGNALQGDFGIS
LKTRRPVITEIGERLMPTVWLTVFAMIWATIFGLLIGVLSAVKRGRWQDYGGMIIAVSGISFPSFWLGLLLIDLFSVRLG
WLPTGGYGTWAHFVMPSFTLGLGVAAVMARFTRSAFVEIAREDYVRTARAKGVPEKTVIWKHTLRNALVPVITMTGLQFG
FLLGGSIVVETVFSWPGLGRLLVDSVSYRDYPVIQAEILLFSLEFIFINLAVDVLYAFANPEIRYK
>Mature_306_residues
MLEYLVKRLLGIIPVIFAISVVVFAFVHLLPGDPARLVAGVDASPEDVAAVRQSLGLEGPLWQQYVRFAGNALQGDFGIS
LKTRRPVITEIGERLMPTVWLTVFAMIWATIFGLLIGVLSAVKRGRWQDYGGMIIAVSGISFPSFWLGLLLIDLFSVRLG
WLPTGGYGTWAHFVMPSFTLGLGVAAVMARFTRSAFVEIAREDYVRTARAKGVPEKTVIWKHTLRNALVPVITMTGLQFG
FLLGGSIVVETVFSWPGLGRLLVDSVSYRDYPVIQAEILLFSLEFIFINLAVDVLYAFANPEIRYK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=66.0130718954248, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=43.1952662721894, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1789888, Length=308, Percent_Identity=38.961038961039, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1787761, Length=299, Percent_Identity=38.7959866220736, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=34.0909090909091, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=31.7689530685921, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788504, Length=363, Percent_Identity=27.8236914600551, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33857; Mature: 33857

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYLVKRLLGIIPVIFAISVVVFAFVHLLPGDPARLVAGVDASPEDVAAVRQSLGLEGP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHHCCCCCH
LWQQYVRFAGNALQGDFGISLKTRRPVITEIGERLMPTVWLTVFAMIWATIFGLLIGVLS
HHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVKRGRWQDYGGMIIAVSGISFPSFWLGLLLIDLFSVRLGWLPTGGYGTWAHFVMPSFTL
HHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GLGVAAVMARFTRSAFVEIAREDYVRTARAKGVPEKTVIWKHTLRNALVPVITMTGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVETVFSWPGLGRLLVDSVSYRDYPVIQAEILLFSLEFIFINLAVDVLYAFAN
HHHCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEIRYK
CCCCCC
>Mature Secondary Structure
MLEYLVKRLLGIIPVIFAISVVVFAFVHLLPGDPARLVAGVDASPEDVAAVRQSLGLEGP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHHCCCCCH
LWQQYVRFAGNALQGDFGISLKTRRPVITEIGERLMPTVWLTVFAMIWATIFGLLIGVLS
HHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVKRGRWQDYGGMIIAVSGISFPSFWLGLLLIDLFSVRLGWLPTGGYGTWAHFVMPSFTL
HHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GLGVAAVMARFTRSAFVEIAREDYVRTARAKGVPEKTVIWKHTLRNALVPVITMTGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVETVFSWPGLGRLLVDSVSYRDYPVIQAEILLFSLEFIFINLAVDVLYAFAN
HHHCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEIRYK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]