Click here to switch to the map view.

The map label for this gene is phoA [H]

Identifier: 158424609

GI number: 158424609

Start: 3413362

End: 3415104

Strand: Direct

Name: phoA [H]

Synonym: AZC_2985

Alternate gene names: 158424609

Gene position: 3413362-3415104 (Clockwise)

Preceding gene: 158424608

Following gene: 158424610

Centisome position: 63.57

GC content: 64.95

Gene sequence:

>1743_bases
ATGCGCCGGCTTCTTGCAGCTCTCGCCCTCAGCACCGCTCTCGCCGGCACCGCCGGCGCGACCGCCATCTATCCACTCGA
CCGCGCCACCATCCTTGCCGGCTCGCCCTTCGACCTGAAGGTGGAGTTCGACAAGGAAGTGCAGCCGCAGGACGTGAGCA
TCACCATCAACGGCCAGCCCGTTGAGCAGGTGCTGGGCAAGAAGCCCGACTTCATCGCCAAGGAAGAGGGCGTGAACGCC
TCGGCCGTGCTCCTGCGCGCCGCAGCCTTCCCCAAGCCCGGCACCTACAAGGTGGAAGCGAAGGCTGGCGGCGAGACCAA
GACAGTGACCTGGGACGTCTATGCCACGGCGGCGACCCCCAAGGCCAAGAACGTCATCTTCTTCCTCGGTGACGGCCTCT
CGGTGGCGCACCGCACCGGCGCCCGCCTCATGTCCAAGGGCATGACCGAGGGCAAGGCGAATGGTCGCCTGAACATCGAC
GATTTCGAGCGGATGGCCTTCATCGGCACCTCGTCGACCAACGCCATCGCCACCGACAGTGCCAACACCATGTCGGCCTA
TATGACGGGCCACAAGACGGCGGTGAACGCGCTCGGCGTCTATGCGGACCGCACCAAGTCCACGCTGGATGATCCCAAGG
TCGAGACCATCGCGGAAGCCATCCGCCGCACGTCCAAGAAGTCGGTGGGCATCGTCACCGGCGCCGAGGTGGAGGACGCC
ACCCCCGCCGCCGTGGTCGCCCACACCCGCGCCCGCGCCGACAAGGCCGACATCGTCGGCATGATGCTGGATGTGAAGCC
GGACGTGGTGCTGGGCGGTGGTTCGGCCTACTTCCTGCCGAAGACGACCCCCGGCTCCAAGCGCAAGGACGACAAGGACT
ATATCCAGCTCTTCAAGGATGCGGGCTATACCCTCGCCACCGACAAGACGGAACTCGCGTCGGCCGCCGGCACCAACACC
GGCAAGATCCTCGGCCTGTTCCACCCCGCCAACATGGACGTGACGCTCGACCGCGAGTTCCTGAAGAAAGGCACGGTGGA
GAAGTTCCCGAACCAGCCCGGCCTCGTGGAAATGACCAAGGTGGCGCTGAACCAGCTCGCCAAGAATCCGGACGGCTTCT
TCCTGATGGTGGAAGGCGCCTCCATCGACAAGATGTCCCATCCCATGGACTGGGAGCGGGCGCTGTTCGAGACCATCGAG
TTCGATCAGGCGGTGGGCGTCGGCATCGAATTCCTGAAGACCCATCCGGACACGCTCATCGTCGTGACCGGCGACCACAC
CCACGGCATCTCCATCATCGGCACCATCGACGACAACAAGCCCGGCCCGGACATGCGGGACAAGGTGGGCGTCTATGCGG
ATGCCGGCTTCCCGAACTATGAGGACAAGAACGGCGACGGCTTCCCCGACAAGGTGGACGTCTCCCGCCGTCTCGCGGTC
TTCGCGTCCAACTATCCGGACTATTACGAGACCTGGCGCCCGAAGATGGACGGCCCGTTCGATCCGGCGGTGCAGAACGA
AAAGAAGCAGTACGTGGCCAATGAGGCCTATAAGAATGTGCCCGGCGCCACCTTCCGGGAAGGCAATCTGCCCCGCTCCG
CGGACACCGCCGTCCATGCGGTGGACGACGTGGTGCTGCAGGCCACCGGCGCCGGCGCCGACGGCTTCAAGGGCTACATG
GAAGAGAGCGACGTCTATCGCGTCCTGGTGGACGTGATGGCCCTCGCCCCGGCCAAGAACTGA

Upstream 100 bases:

>100_bases
ACGTAGCGGCAGGCGGTGCTTGCACGCCGCAATGTTCACGCAACTGTCATGCAACCGGCCTAGGGGATGCCGCAGCGCCA
TCCCCTAGGAGAACCCGTCG

Downstream 100 bases:

>100_bases
GCCCATCCCCCTTAAAAGCCCTCCCCCCTCGTGGGGGAGGGTTGGGTGGGGGGTAGAACGCCCGGGGGCCGGCACCACTG
CCGAAGTGACGTCCTTTATG

Product: alkaline phosphatase

Products: NA

Alternate protein names: APase [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MRRLLAALALSTALAGTAGATAIYPLDRATILAGSPFDLKVEFDKEVQPQDVSITINGQPVEQVLGKKPDFIAKEEGVNA
SAVLLRAAAFPKPGTYKVEAKAGGETKTVTWDVYATAATPKAKNVIFFLGDGLSVAHRTGARLMSKGMTEGKANGRLNID
DFERMAFIGTSSTNAIATDSANTMSAYMTGHKTAVNALGVYADRTKSTLDDPKVETIAEAIRRTSKKSVGIVTGAEVEDA
TPAAVVAHTRARADKADIVGMMLDVKPDVVLGGGSAYFLPKTTPGSKRKDDKDYIQLFKDAGYTLATDKTELASAAGTNT
GKILGLFHPANMDVTLDREFLKKGTVEKFPNQPGLVEMTKVALNQLAKNPDGFFLMVEGASIDKMSHPMDWERALFETIE
FDQAVGVGIEFLKTHPDTLIVVTGDHTHGISIIGTIDDNKPGPDMRDKVGVYADAGFPNYEDKNGDGFPDKVDVSRRLAV
FASNYPDYYETWRPKMDGPFDPAVQNEKKQYVANEAYKNVPGATFREGNLPRSADTAVHAVDDVVLQATGAGADGFKGYM
EESDVYRVLVDVMALAPAKN

Sequences:

>Translated_580_residues
MRRLLAALALSTALAGTAGATAIYPLDRATILAGSPFDLKVEFDKEVQPQDVSITINGQPVEQVLGKKPDFIAKEEGVNA
SAVLLRAAAFPKPGTYKVEAKAGGETKTVTWDVYATAATPKAKNVIFFLGDGLSVAHRTGARLMSKGMTEGKANGRLNID
DFERMAFIGTSSTNAIATDSANTMSAYMTGHKTAVNALGVYADRTKSTLDDPKVETIAEAIRRTSKKSVGIVTGAEVEDA
TPAAVVAHTRARADKADIVGMMLDVKPDVVLGGGSAYFLPKTTPGSKRKDDKDYIQLFKDAGYTLATDKTELASAAGTNT
GKILGLFHPANMDVTLDREFLKKGTVEKFPNQPGLVEMTKVALNQLAKNPDGFFLMVEGASIDKMSHPMDWERALFETIE
FDQAVGVGIEFLKTHPDTLIVVTGDHTHGISIIGTIDDNKPGPDMRDKVGVYADAGFPNYEDKNGDGFPDKVDVSRRLAV
FASNYPDYYETWRPKMDGPFDPAVQNEKKQYVANEAYKNVPGATFREGNLPRSADTAVHAVDDVVLQATGAGADGFKGYM
EESDVYRVLVDVMALAPAKN
>Mature_580_residues
MRRLLAALALSTALAGTAGATAIYPLDRATILAGSPFDLKVEFDKEVQPQDVSITINGQPVEQVLGKKPDFIAKEEGVNA
SAVLLRAAAFPKPGTYKVEAKAGGETKTVTWDVYATAATPKAKNVIFFLGDGLSVAHRTGARLMSKGMTEGKANGRLNID
DFERMAFIGTSSTNAIATDSANTMSAYMTGHKTAVNALGVYADRTKSTLDDPKVETIAEAIRRTSKKSVGIVTGAEVEDA
TPAAVVAHTRARADKADIVGMMLDVKPDVVLGGGSAYFLPKTTPGSKRKDDKDYIQLFKDAGYTLATDKTELASAAGTNT
GKILGLFHPANMDVTLDREFLKKGTVEKFPNQPGLVEMTKVALNQLAKNPDGFFLMVEGASIDKMSHPMDWERALFETIE
FDQAVGVGIEFLKTHPDTLIVVTGDHTHGISIIGTIDDNKPGPDMRDKVGVYADAGFPNYEDKNGDGFPDKVDVSRRLAV
FASNYPDYYETWRPKMDGPFDPAVQNEKKQYVANEAYKNVPGATFREGNLPRSADTAVHAVDDVVLQATGAGADGFKGYM
EESDVYRVLVDVMALAPAKN

Specific function: Unknown

COG id: COG1785

COG function: function code P; Alkaline phosphatase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkaline phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI116734717, Length=343, Percent_Identity=32.9446064139942, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI157266296, Length=345, Percent_Identity=34.2028985507246, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI94721246, Length=345, Percent_Identity=33.6231884057971, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI294660770, Length=338, Percent_Identity=31.9526627218935, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI157266292, Length=345, Percent_Identity=32.463768115942, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI294660772, Length=294, Percent_Identity=31.9727891156463, Blast_Score=124, Evalue=3e-28,
Organism=Escherichia coli, GI48994877, Length=359, Percent_Identity=33.1476323119777, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320689, Length=341, Percent_Identity=30.791788856305, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21358067, Length=368, Percent_Identity=35.054347826087, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24657835, Length=394, Percent_Identity=32.2335025380711, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI19921912, Length=499, Percent_Identity=29.4589178356713, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21355981, Length=341, Percent_Identity=33.7243401759531, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI21355149, Length=479, Percent_Identity=28.1837160751566, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24657842, Length=397, Percent_Identity=30.7304785894207, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21355151, Length=346, Percent_Identity=31.2138728323699, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24657827, Length=352, Percent_Identity=33.5227272727273, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24651554, Length=514, Percent_Identity=27.431906614786, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI85725200, Length=356, Percent_Identity=32.0224719101124, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI85815833, Length=356, Percent_Identity=32.0224719101124, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859923, Length=339, Percent_Identity=30.3834808259587, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24651556, Length=475, Percent_Identity=27.1578947368421, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585213, Length=359, Percent_Identity=28.6908077994429, Blast_Score=106, Evalue=5e-23,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR001952
- InterPro:   IPR018299
- InterPro:   IPR017850 [H]

Pfam domain/function: PF00245 Alk_phosphatase [H]

EC number: =3.1.3.1 [H]

Molecular weight: Translated: 62294; Mature: 62294

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLAALALSTALAGTAGATAIYPLDRATILAGSPFDLKVEFDKEVQPQDVSITINGQP
CHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCEEEEEEECCCCCCCEEEEEECCCH
VEQVLGKKPDFIAKEEGVNASAVLLRAAAFPKPGTYKVEAKAGGETKTVTWDVYATAATP
HHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEEEEECCC
KAKNVIFFLGDGLSVAHRTGARLMSKGMTEGKANGRLNIDDFERMAFIGTSSTNAIATDS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCEEEEEECCCCCEEEECC
ANTMSAYMTGHKTAVNALGVYADRTKSTLDDPKVETIAEAIRRTSKKSVGIVTGAEVEDA
CCCEEEECCCCHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCC
TPAAVVAHTRARADKADIVGMMLDVKPDVVLGGGSAYFLPKTTPGSKRKDDKDYIQLFKD
CCHHEEEHHHHCCCCHHEEEEEEECCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHH
AGYTLATDKTELASAAGTNTGKILGLFHPANMDVTLDREFLKKGTVEKFPNQPGLVEMTK
CCCEEECCHHHHHHHCCCCCCEEEEEEECCCCCEEECHHHHHCCCHHHCCCCCCHHHHHH
VALNQLAKNPDGFFLMVEGASIDKMSHPMDWERALFETIEFDQAVGVGIEFLKTHPDTLI
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEECCCCEEE
VVTGDHTHGISIIGTIDDNKPGPDMRDKVGVYADAGFPNYEDKNGDGFPDKVDVSRRLAV
EEECCCCCCEEEEEEECCCCCCCCHHHCCCEEECCCCCCCCCCCCCCCCCHHCHHHEEEE
FASNYPDYYETWRPKMDGPFDPAVQNEKKQYVANEAYKNVPGATFREGNLPRSADTAVHA
EECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
VDDVVLQATGAGADGFKGYMEESDVYRVLVDVMALAPAKN
HHHEEEEECCCCCCCHHHHHCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRRLLAALALSTALAGTAGATAIYPLDRATILAGSPFDLKVEFDKEVQPQDVSITINGQP
CHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCEEEEEEECCCCCCCEEEEEECCCH
VEQVLGKKPDFIAKEEGVNASAVLLRAAAFPKPGTYKVEAKAGGETKTVTWDVYATAATP
HHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEEEEECCC
KAKNVIFFLGDGLSVAHRTGARLMSKGMTEGKANGRLNIDDFERMAFIGTSSTNAIATDS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCEEEEEECCCCCEEEECC
ANTMSAYMTGHKTAVNALGVYADRTKSTLDDPKVETIAEAIRRTSKKSVGIVTGAEVEDA
CCCEEEECCCCHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCC
TPAAVVAHTRARADKADIVGMMLDVKPDVVLGGGSAYFLPKTTPGSKRKDDKDYIQLFKD
CCHHEEEHHHHCCCCHHEEEEEEECCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHH
AGYTLATDKTELASAAGTNTGKILGLFHPANMDVTLDREFLKKGTVEKFPNQPGLVEMTK
CCCEEECCHHHHHHHCCCCCCEEEEEEECCCCCEEECHHHHHCCCHHHCCCCCCHHHHHH
VALNQLAKNPDGFFLMVEGASIDKMSHPMDWERALFETIEFDQAVGVGIEFLKTHPDTLI
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEECCCCEEE
VVTGDHTHGISIIGTIDDNKPGPDMRDKVGVYADAGFPNYEDKNGDGFPDKVDVSRRLAV
EEECCCCCCEEEEEEECCCCCCCCHHHCCCEEECCCCCCCCCCCCCCCCCHHCHHHEEEE
FASNYPDYYETWRPKMDGPFDPAVQNEKKQYVANEAYKNVPGATFREGNLPRSADTAVHA
EECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
VDDVVLQATGAGADGFKGYMEESDVYRVLVDVMALAPAKN
HHHEEEEECCCCCCCHHHHHCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129542 [H]