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The map label for this gene is lysR [H]

Identifier: 158424526

GI number: 158424526

Start: 3313694

End: 3314719

Strand: Direct

Name: lysR [H]

Synonym: AZC_2902

Alternate gene names: 158424526

Gene position: 3313694-3314719 (Clockwise)

Preceding gene: 158424523

Following gene: 158424530

Centisome position: 61.71

GC content: 70.57

Gene sequence:

>1026_bases
TTGATGGGTGCTCGCGGGCGGTGTCCAATGCGTTTGTGGCAAGCCGCGATGAGCGGGCTGCATCGGACCCGGCCCGAACC
GGCGGCGGGCGGCGGCAGAGGCAAGGGGCGGATCTTGATCGAACTGAAGCGGCTGCGGCAGGTGGTGGCACTTGCGGACA
GCGGCAATTTCGCCCGGGCGGCACAAGCCCTCCACATGTCCCAGCCGGCGCTCAGCCGCAGCATTCAGGATCTGGAAAAG
CAGCTCGGCGCCCCCCTGTTCGAGCGCCCGCCACGGGAAATTCGCCCCACCTCCCTCGGCGCGCTCATCGTCGAGGAGGG
GCGCGAACTCCTGCGCCGGGCAGCGGCCCTCGATGCGGCGATTGCCGATCACAGGGGCCTCAGCCGGACGGTCGTGTTCG
GCTCCGGGCTTTATTCCAACGTCACGCTCGTGCCGCGCGCCATCGCCGCCTTCGCCGCGCAGCAGCCGGACGTGCAGGTG
AAGGTGATGGCCGGCGGCTGGCGCGACTGCCGCGACATGCTCGAGCGCGGGGCCATGGACTTCTTCATCGGCGAGCGCAC
GGATGACGAGCACGCCGAGGCCTATCGCGAGCGGCCGCTGCGCGAGCGGCAGGGTTGTGTCGTGGTCCGCAAAGGCCACC
CGCTGTGCGCCCTGCACGCCTGCACGCTGGCCGACATCGCCCAATATCCCTTCGCGGGCGCCCGCCTGCCCGAGCGGATC
GCCCGGCATTTTCCGCGCAAGGCGAAGCTCGGGCGCCCCGATGCGGGCGGCAAGCTGCTGGTGCCGCGGTTCGAAGCCTA
TTCCTGGACCGCCATCAGCGCGATCGTGCAGGACAGCGACGCGGTGGCATTCGGGAGCGCGTCGCTGGTGGCGGAGAGTG
GCGGCGCTCTCGTGTGCCTCGACGTCGTGCTGCCCTGGCTGCGCTATGTGGGCGCCGTGGTCTGGCGCGCGGAGCGCGGG
CTCTCCTCCAGCGCCCAGAGCTTTGCCGACGTGGCCATCGAGATCGACGCAACGCTGCCGGACTGA

Upstream 100 bases:

>100_bases
TTCGTGCCCCAGGACCAAGTGATCGTCGTGGTCTTAGCCATCGTCCACCCATCGTTGCCGCATTACCCTTACGTCCGACG
GCACGGACGCGAACGGTAGC

Downstream 100 bases:

>100_bases
CCGCATGAAAACGGCCGGGACGCGCGAGGCGTCCCGGCCGCTCATGAACCCGTCTTGGGGAGGGGGAGATCAGACGGGAT
GCATGAAGAACTGGGCGATG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MMGARGRCPMRLWQAAMSGLHRTRPEPAAGGGRGKGRILIELKRLRQVVALADSGNFARAAQALHMSQPALSRSIQDLEK
QLGAPLFERPPREIRPTSLGALIVEEGRELLRRAAALDAAIADHRGLSRTVVFGSGLYSNVTLVPRAIAAFAAQQPDVQV
KVMAGGWRDCRDMLERGAMDFFIGERTDDEHAEAYRERPLRERQGCVVVRKGHPLCALHACTLADIAQYPFAGARLPERI
ARHFPRKAKLGRPDAGGKLLVPRFEAYSWTAISAIVQDSDAVAFGSASLVAESGGALVCLDVVLPWLRYVGAVVWRAERG
LSSSAQSFADVAIEIDATLPD

Sequences:

>Translated_341_residues
MMGARGRCPMRLWQAAMSGLHRTRPEPAAGGGRGKGRILIELKRLRQVVALADSGNFARAAQALHMSQPALSRSIQDLEK
QLGAPLFERPPREIRPTSLGALIVEEGRELLRRAAALDAAIADHRGLSRTVVFGSGLYSNVTLVPRAIAAFAAQQPDVQV
KVMAGGWRDCRDMLERGAMDFFIGERTDDEHAEAYRERPLRERQGCVVVRKGHPLCALHACTLADIAQYPFAGARLPERI
ARHFPRKAKLGRPDAGGKLLVPRFEAYSWTAISAIVQDSDAVAFGSASLVAESGGALVCLDVVLPWLRYVGAVVWRAERG
LSSSAQSFADVAIEIDATLPD
>Mature_341_residues
MMGARGRCPMRLWQAAMSGLHRTRPEPAAGGGRGKGRILIELKRLRQVVALADSGNFARAAQALHMSQPALSRSIQDLEK
QLGAPLFERPPREIRPTSLGALIVEEGRELLRRAAALDAAIADHRGLSRTVVFGSGLYSNVTLVPRAIAAFAAQQPDVQV
KVMAGGWRDCRDMLERGAMDFFIGERTDDEHAEAYRERPLRERQGCVVVRKGHPLCALHACTLADIAQYPFAGARLPERI
ARHFPRKAKLGRPDAGGKLLVPRFEAYSWTAISAIVQDSDAVAFGSASLVAESGGALVCLDVVLPWLRYVGAVVWRAERG
LSSSAQSFADVAIEIDATLPD

Specific function: Activates the transcription of the sdsA gene for sodium dodecyl sulfate (SDS) degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=199, Percent_Identity=27.1356783919598, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787601, Length=176, Percent_Identity=30.6818181818182, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI157672245, Length=297, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790399, Length=190, Percent_Identity=28.9473684210526, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788887, Length=195, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081904, Length=199, Percent_Identity=31.1557788944724, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787530, Length=197, Percent_Identity=25.8883248730964, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787879, Length=201, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790262, Length=212, Percent_Identity=27.8301886792453, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367136, Length=81, Percent_Identity=45.679012345679, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37032; Mature: 37032

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGARGRCPMRLWQAAMSGLHRTRPEPAAGGGRGKGRILIELKRLRQVVALADSGNFARA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHH
AQALHMSQPALSRSIQDLEKQLGAPLFERPPREIRPTSLGALIVEEGRELLRRAAALDAA
HHHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IADHRGLSRTVVFGSGLYSNVTLVPRAIAAFAAQQPDVQVKVMAGGWRDCRDMLERGAMD
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCEE
FFIGERTDDEHAEAYRERPLRERQGCVVVRKGHPLCALHACTLADIAQYPFAGARLPERI
EECCCCCCHHHHHHHHHCCCHHHCCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCHHHH
ARHFPRKAKLGRPDAGGKLLVPRFEAYSWTAISAIVQDSDAVAFGSASLVAESGGALVCL
HHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEECCHHHHCCCCCCEEEH
DVVLPWLRYVGAVVWRAERGLSSSAQSFADVAIEIDATLPD
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEEECCCCC
>Mature Secondary Structure
MMGARGRCPMRLWQAAMSGLHRTRPEPAAGGGRGKGRILIELKRLRQVVALADSGNFARA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHH
AQALHMSQPALSRSIQDLEKQLGAPLFERPPREIRPTSLGALIVEEGRELLRRAAALDAA
HHHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IADHRGLSRTVVFGSGLYSNVTLVPRAIAAFAAQQPDVQVKVMAGGWRDCRDMLERGAMD
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCEE
FFIGERTDDEHAEAYRERPLRERQGCVVVRKGHPLCALHACTLADIAQYPFAGARLPERI
EECCCCCCHHHHHHHHHCCCHHHCCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCHHHH
ARHFPRKAKLGRPDAGGKLLVPRFEAYSWTAISAIVQDSDAVAFGSASLVAESGGALVCL
HHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEECCHHHHCCCCCCEEEH
DVVLPWLRYVGAVVWRAERGLSSSAQSFADVAIEIDATLPD
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587481 [H]