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The map label for this gene is lysR [H]

Identifier: 158424530

GI number: 158424530

Start: 3318734

End: 3319705

Strand: Direct

Name: lysR [H]

Synonym: AZC_2906

Alternate gene names: 158424530

Gene position: 3318734-3319705 (Clockwise)

Preceding gene: 158424526

Following gene: 158424536

Centisome position: 61.8

GC content: 67.8

Gene sequence:

>972_bases
ATGGCCGGTTCCGTATTGTTGACTCCAAGGCAACGCTTGGACCCGACCGTGACATCCCCGCTCGACGATCATCGCCTGCG
CTACCTCTATGAGGCCATCCGCCTTGGCTCCGTGCGGGCAGCGGCCGACCATCTGGCGGTCAATGCCTCCGTGGTCTCAC
GCCAGATCGCGCATCTGGAGAAGGATCTCGGCCTTCTGCTCATCGAACGGCTGGGGCGGGGCGTGCGGGCGACGGAGGCG
GGCGAGCTTTTGGCCCAGCGTTTCCGCCAGTGGACCGCCGACCGGGAGGACACGCTCGCCAAGCTGAACGAGCTTCAGGG
CCTGAAGCGCGGCCACCTCGACATCATCTCGGGCGAGGGATTCGTCAGCGACCTGATCGCCGGCCCCCTCACCCGCTTCT
GGGAGCGCCATCCCAACCTCACCATGTCAGTGGAGGTGGCGAGCACCAATGACGTGATCCGGGGTGTCGCCGAGGATCGC
TACCATATCGGGCTCGTCTACAACGCCCCGCCCGACCCGCGCCTGCGGACAGCGGCATCGAGCCGCCAGCCCATCTGCCT
TGTGGTGTCACCGGACCATCCCCTCGCCCGGCAAGGGGCTCCGGTGCCCCTTCGCGCGGTGGCGGAACTGCCTGTGGGGC
TGATGCACGCGCGCTATGGCACGCGGCAGATCGTGGCCATGGCGGAGATGGCGGAGAAGGTCACGCTGGCCCCGGTTCTC
ACCACCGGCTCCATCTATGTGCTGCGGGAATTCGTGAAGAGCGGCCGGGGCGTCACGCTACTGCCGGCCTTCGCCATCGC
CTCCGACATGGCGGCGGGGGAACTCGTGGCGCTGCCCATGGAGAATCCGCTGCTGCTGTCGGTGGAGGCCCGACTCATCA
CCCGTCTCGGCCGCCAGTTGCCGAGCGCCGCCGCCCAGTTGCTCCGCGTGCTGATCGGGCAGCTCAAGGCCTTCCATGCC
GCAGGCACATAG

Upstream 100 bases:

>100_bases
GCCCCATATTGCCGAGACCGATCACACCAACGTTCGCCACGCGCGTCTCCTCGAAACTTGCCCAGAAAAGCTACGCGGCT
GTTTTGGCGGCAGACAGGAG

Downstream 100 bases:

>100_bases
CTACCTCCGCCGAAAAGCGGATTATTCCTCCATACTGGAATGAAGGAGGATAGCTGACCATAGGTGACCGCCATTCTGGA
GATGAATGGCGTTGCTTGGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAGSVLLTPRQRLDPTVTSPLDDHRLRYLYEAIRLGSVRAAADHLAVNASVVSRQIAHLEKDLGLLLIERLGRGVRATEA
GELLAQRFRQWTADREDTLAKLNELQGLKRGHLDIISGEGFVSDLIAGPLTRFWERHPNLTMSVEVASTNDVIRGVAEDR
YHIGLVYNAPPDPRLRTAASSRQPICLVVSPDHPLARQGAPVPLRAVAELPVGLMHARYGTRQIVAMAEMAEKVTLAPVL
TTGSIYVLREFVKSGRGVTLLPAFAIASDMAAGELVALPMENPLLLSVEARLITRLGRQLPSAAAQLLRVLIGQLKAFHA
AGT

Sequences:

>Translated_323_residues
MAGSVLLTPRQRLDPTVTSPLDDHRLRYLYEAIRLGSVRAAADHLAVNASVVSRQIAHLEKDLGLLLIERLGRGVRATEA
GELLAQRFRQWTADREDTLAKLNELQGLKRGHLDIISGEGFVSDLIAGPLTRFWERHPNLTMSVEVASTNDVIRGVAEDR
YHIGLVYNAPPDPRLRTAASSRQPICLVVSPDHPLARQGAPVPLRAVAELPVGLMHARYGTRQIVAMAEMAEKVTLAPVL
TTGSIYVLREFVKSGRGVTLLPAFAIASDMAAGELVALPMENPLLLSVEARLITRLGRQLPSAAAQLLRVLIGQLKAFHA
AGT
>Mature_322_residues
AGSVLLTPRQRLDPTVTSPLDDHRLRYLYEAIRLGSVRAAADHLAVNASVVSRQIAHLEKDLGLLLIERLGRGVRATEAG
ELLAQRFRQWTADREDTLAKLNELQGLKRGHLDIISGEGFVSDLIAGPLTRFWERHPNLTMSVEVASTNDVIRGVAEDRY
HIGLVYNAPPDPRLRTAASSRQPICLVVSPDHPLARQGAPVPLRAVAELPVGLMHARYGTRQIVAMAEMAEKVTLAPVLT
TGSIYVLREFVKSGRGVTLLPAFAIASDMAAGELVALPMENPLLLSVEARLITRLGRQLPSAAAQLLRVLIGQLKAFHAA
GT

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=295, Percent_Identity=27.7966101694915, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082132, Length=263, Percent_Identity=25.4752851711027, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788481, Length=264, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081978, Length=300, Percent_Identity=25, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786401, Length=257, Percent_Identity=25.6809338521401, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=27.8225806451613, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787601, Length=179, Percent_Identity=26.2569832402235, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI145693105, Length=250, Percent_Identity=21.2, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35112; Mature: 34981

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSVLLTPRQRLDPTVTSPLDDHRLRYLYEAIRLGSVRAAADHLAVNASVVSRQIAHLE
CCCCEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KDLGLLLIERLGRGVRATEAGELLAQRFRQWTADREDTLAKLNELQGLKRGHLDIISGEG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCC
FVSDLIAGPLTRFWERHPNLTMSVEVASTNDVIRGVAEDRYHIGLVYNAPPDPRLRTAAS
HHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHCC
SRQPICLVVSPDHPLARQGAPVPLRAVAELPVGLMHARYGTRQIVAMAEMAEKVTLAPVL
CCCCEEEEECCCCCHHHCCCCCCHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHEEEEEE
TTGSIYVLREFVKSGRGVTLLPAFAIASDMAAGELVALPMENPLLLSVEARLITRLGRQL
ECCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHC
PSAAAQLLRVLIGQLKAFHAAGT
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGSVLLTPRQRLDPTVTSPLDDHRLRYLYEAIRLGSVRAAADHLAVNASVVSRQIAHLE
CCCEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KDLGLLLIERLGRGVRATEAGELLAQRFRQWTADREDTLAKLNELQGLKRGHLDIISGEG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCC
FVSDLIAGPLTRFWERHPNLTMSVEVASTNDVIRGVAEDRYHIGLVYNAPPDPRLRTAAS
HHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHCC
SRQPICLVVSPDHPLARQGAPVPLRAVAELPVGLMHARYGTRQIVAMAEMAEKVTLAPVL
CCCCEEEEECCCCCHHHCCCCCCHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHEEEEEE
TTGSIYVLREFVKSGRGVTLLPAFAIASDMAAGELVALPMENPLLLSVEARLITRLGRQL
ECCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHC
PSAAAQLLRVLIGQLKAFHAAGT
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA