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The map label for this gene is mcpA [H]

Identifier: 158424452

GI number: 158424452

Start: 3219890

End: 3221665

Strand: Direct

Name: mcpA [H]

Synonym: AZC_2828

Alternate gene names: 158424452

Gene position: 3219890-3221665 (Clockwise)

Preceding gene: 158424451

Following gene: 158424455

Centisome position: 59.96

GC content: 67.17

Gene sequence:

>1776_bases
ATGAGCGGTTTGCCGGTCCCGTTGTGTTGGGCTGGGGGGAACAGCCGTCCCCATGTGCCAGTGATGGGGGATCGCATGTC
TTTCAAAAACCTATCGGTCATGCTCAAGATCGGCGCGATTGTTCTGATGCTCAGCGCATGTGCTGGCGTCGGCGTAGCAC
TGCTGAGCAGTCAGTTGCACACCGTGATCGGCACCTACGATGCCGTCATCAAGAATGACGAAGCCGCAGTGCTGGCTCTC
GTCCGGTACAATCGCCAGGTCGCCGTGCTCCAGCGCGCCCTCTATCAGATCGCGGTGGCGTCGACGCCGGAACAGTCGGC
GGCGGCCGACAAGGAGCTGTCGGATGCCCTGGCAGCCATGAACAACCGCCTCAAGGAAGCCAAGGCGGCGTCCGAGCAGG
TTGGTGCGATCGCCCAGTCGTTCAGCGCACGGGTGGACGCGGCCATGGCGAGCCCCTGCGGCCCCGTGATCAAATTCGCT
CGCGAGGCGATGGACCCGCAGTCCATCGTCACCGCCGGCCAGCGCATGACCAACGAGTGCGATGCCGCCCTGAAGCCCAT
CGGGCAGGAGATCGTGCGAGCCAATGATCGCATAACGGCGGAGTTGAACCAGCGCACCGACGCCGTGCGCGACGATGCGC
TGCGCCTCGCCACGCTCATCACCACCGCGCTCGCCATCGCCGTCCTCGTCTGCTTCGGCCTCGGCTTCGCCGTCGCCCGC
TATGGCATCGTGGTGCCCATCAATCGCGTGCTCGGCGTGATGTCGGACATCCAGGCCGGCAAGCTTCAGGTCAAGGTGCC
TGATACGGATCGCGGTGACGAGGTGGGCACCATCGCCAAGAGCGTGGAAACCTTCCGCCAGGGCCTTGAGGAAGCCGAGC
GCCTGCGGCAGGAGGCCGCCCTTCAGGAGCAGCGTTCCGCCGAGAAGGTGCGCAACGAGCGCCTCCAGATCGCGGCGAAT
TTCGAGGCGACCATGGGCAATCTCGCCCGCGCCTTCGCGCAGTCGTCCCACGAGATGTCCGATGCCGCCCGGAGCCTTGC
CGCCACCGCCGAGGAGACCTCCCGCCAGGCGGAAGCCGTGGGCGGGGCGGCCGAGGAAGCCAGCACCAACGTGAACACCG
TCGCCGCCTCCACCGAGGAGATGACCGCCTCCATCCGCGAGATTTCGGCGCAGGTCTCGCAGACCGCCACCATCGCCACC
GCCGCCGCGGCGGAAACCTCCCGCACGCAGACCGAGATCATCGAGCTCTCCCAGTCGGCGGCCAAGATCGGCGAAGTGGT
GGATCTCATCACCAACATCGCCAGCCAGACCAACCTGCTGGCGCTCAACGCCACCATCGAGGCAGCACGCGCCGGCGAGA
GTGGCAAGGGCTTCGCCGTGGTGGCGCAGGAGGTGAAGCAGCTCGCCGCCCAGACCGCCAAGGCCACCGAGGAGATCGCC
GGCAAGGTGGGCGAGATCCAGCAGGCCACCAACCGCTCGGTGGAATCCATCGACCGCATCGTGACCACCATCGGCCAGAT
CCAGACGGCGGCCTCCACCGTCGCCTCGGCGGTCGAGGAACAGGGCGCCGCCACCGCCGAGATTGCCAGCAACACCCAGC
AGGCGGCGCGCGGCACGGAGACGGTGAACCACAACATCGCCGGCGTCGGCCGCGCCGCCGAAATGACCGGCGCTGCGTCC
AGCCAGCTCATGACGCTGTCCCAGTCGATCACCGACCAGGCCCAGCAGCTCAAGCGGGAAGTGGAACAGGTGGTGGCGAA
CCTGCGGGCCGGCTGA

Upstream 100 bases:

>100_bases
CCTCGCGCACGGGGCTCTTTTCACGCCTTGCGGCAATTGGGCCCATGACAGGCGATTACAAGGCTCGCGCAAGCATGCGG
TACGCTCATACATCCACCAC

Downstream 100 bases:

>100_bases
TCGCCACTATCTCTTGGAAACAAAACGGAAAGGGCCCCGCACGGGGCCCTTTCACGCATTCCGGGACGGATGTTCGAGGC
GCAGCACGCCGCTACATGAG

Product: histidine kinase

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MSGLPVPLCWAGGNSRPHVPVMGDRMSFKNLSVMLKIGAIVLMLSACAGVGVALLSSQLHTVIGTYDAVIKNDEAAVLAL
VRYNRQVAVLQRALYQIAVASTPEQSAAADKELSDALAAMNNRLKEAKAASEQVGAIAQSFSARVDAAMASPCGPVIKFA
REAMDPQSIVTAGQRMTNECDAALKPIGQEIVRANDRITAELNQRTDAVRDDALRLATLITTALAIAVLVCFGLGFAVAR
YGIVVPINRVLGVMSDIQAGKLQVKVPDTDRGDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIAAN
FEATMGNLARAFAQSSHEMSDAARSLAATAEETSRQAEAVGGAAEEASTNVNTVAASTEEMTASIREISAQVSQTATIAT
AAAAETSRTQTEIIELSQSAAKIGEVVDLITNIASQTNLLALNATIEAARAGESGKGFAVVAQEVKQLAAQTAKATEEIA
GKVGEIQQATNRSVESIDRIVTTIGQIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAAS
SQLMTLSQSITDQAQQLKREVEQVVANLRAG

Sequences:

>Translated_591_residues
MSGLPVPLCWAGGNSRPHVPVMGDRMSFKNLSVMLKIGAIVLMLSACAGVGVALLSSQLHTVIGTYDAVIKNDEAAVLAL
VRYNRQVAVLQRALYQIAVASTPEQSAAADKELSDALAAMNNRLKEAKAASEQVGAIAQSFSARVDAAMASPCGPVIKFA
REAMDPQSIVTAGQRMTNECDAALKPIGQEIVRANDRITAELNQRTDAVRDDALRLATLITTALAIAVLVCFGLGFAVAR
YGIVVPINRVLGVMSDIQAGKLQVKVPDTDRGDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIAAN
FEATMGNLARAFAQSSHEMSDAARSLAATAEETSRQAEAVGGAAEEASTNVNTVAASTEEMTASIREISAQVSQTATIAT
AAAAETSRTQTEIIELSQSAAKIGEVVDLITNIASQTNLLALNATIEAARAGESGKGFAVVAQEVKQLAAQTAKATEEIA
GKVGEIQQATNRSVESIDRIVTTIGQIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAAS
SQLMTLSQSITDQAQQLKREVEQVVANLRAG
>Mature_590_residues
SGLPVPLCWAGGNSRPHVPVMGDRMSFKNLSVMLKIGAIVLMLSACAGVGVALLSSQLHTVIGTYDAVIKNDEAAVLALV
RYNRQVAVLQRALYQIAVASTPEQSAAADKELSDALAAMNNRLKEAKAASEQVGAIAQSFSARVDAAMASPCGPVIKFAR
EAMDPQSIVTAGQRMTNECDAALKPIGQEIVRANDRITAELNQRTDAVRDDALRLATLITTALAIAVLVCFGLGFAVARY
GIVVPINRVLGVMSDIQAGKLQVKVPDTDRGDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIAANF
EATMGNLARAFAQSSHEMSDAARSLAATAEETSRQAEAVGGAAEEASTNVNTVAASTEEMTASIREISAQVSQTATIATA
AAAETSRTQTEIIELSQSAAKIGEVVDLITNIASQTNLLALNATIEAARAGESGKGFAVVAQEVKQLAAQTAKATEEIAG
KVGEIQQATNRSVESIDRIVTTIGQIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAASS
QLMTLSQSITDQAQQLKREVEQVVANLRAG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=341, Percent_Identity=29.0322580645161, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788194, Length=161, Percent_Identity=39.7515527950311, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1787690, Length=272, Percent_Identity=30.5147058823529, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788195, Length=248, Percent_Identity=29.4354838709677, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789453, Length=185, Percent_Identity=32.972972972973, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61864; Mature: 61732

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGLPVPLCWAGGNSRPHVPVMGDRMSFKNLSVMLKIGAIVLMLSACAGVGVALLSSQLH
CCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIGTYDAVIKNDEAAVLALVRYNRQVAVLQRALYQIAVASTPEQSAAADKELSDALAAM
HHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
NNRLKEAKAASEQVGAIAQSFSARVDAAMASPCGPVIKFAREAMDPQSIVTAGQRMTNEC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
DAALKPIGQEIVRANDRITAELNQRTDAVRDDALRLATLITTALAIAVLVCFGLGFAVAR
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGIVVPINRVLGVMSDIQAGKLQVKVPDTDRGDEVGTIAKSVETFRQGLEEAERLRQEAA
CCHHEEHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQEQRSAEKVRNERLQIAANFEATMGNLARAFAQSSHEMSDAARSLAATAEETSRQAEAV
HHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGAAEEASTNVNTVAASTEEMTASIREISAQVSQTATIATAAAAETSRTQTEIIELSQSA
CCCHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKIGEVVDLITNIASQTNLLALNATIEAARAGESGKGFAVVAQEVKQLAAQTAKATEEIA
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GKVGEIQQATNRSVESIDRIVTTIGQIQTAASTVASAVEEQGAATAEIASNTQQAARGTE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
TVNHNIAGVGRAAEMTGAASSQLMTLSQSITDQAQQLKREVEQVVANLRAG
HHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]