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The map label for this gene is mcpA [H]

Identifier: 158424451

GI number: 158424451

Start: 3218054

End: 3219754

Strand: Direct

Name: mcpA [H]

Synonym: AZC_2827

Alternate gene names: 158424451

Gene position: 3218054-3219754 (Clockwise)

Preceding gene: 158424450

Following gene: 158424452

Centisome position: 59.93

GC content: 65.78

Gene sequence:

>1701_bases
ATGTCCTTCAAGAATATGCCGATCATGTTGAAGATCGGCGTCGTGATCCTGCTGTTGGGCGCGTGTGCCATCGGTGGCAC
ATTCATCGCCGGCTCCAAGGTGGCCTCGGTGTCCGAAAGTTATCAGGGCGCCATCAAGGACGATGCCGGCTTTCTGCAAT
TGGCGCGCCTGAACCGTCAGGTCGTTGGAGTTCAGCGGTCGATTTATCAGCTCGTGATTGCCGAAGCGCCGGAGGAGGTC
AAAACGGCCGAGGACCGGCTGACTTCGACGATCAATCTGCTCGACACGCGCGTGAAGGACGCCAAGGCCCTGTTGCCCAA
GCTGTCCGGCCAGATCGACCAGATCGCATCGGACATCAAAGGCGCGCTCGCCGGCAGCGCCTGCGGTCCGACCATCAAGG
CCGCCCGCGAGACCTCTGGCGCGGAGGCGATCGTCAAGGCAGGACGCATGATGGTCAACGAATGCGATCCGGTGCTGCGC
GGCTCCGTCGAGAGCATCACCAAGCTGATCGATGCGGCGGTCATCGAGAACAAGAAGTCTCTCTCGGAGCTGGAAGCCGC
CACTGCCAGCACGATCATGTCCCTCAACATTGTGATGGGCCTTGCTGTCTTCGTGTCGCTCGTCATCGCCGGTCTGGTGG
CCCGTTTCGGCATCGTGAAGCCCATCAACGGCCTGCTTGCGGTGATGACGCAGATCCAGAGTGGCAATCTCTCCGTGACG
GTGCCGGACACCGAGCGCCGCGACGAAGTGGGCACCATCGCCAAGAGCGTCGAGACGTTCCGCCAGGGCCTTGAGGAAGC
CGAGCGCCTGCGGCAGGAGGCGGCCCTTCAGGAGCAGCGTTCCGCCGAGAAGGTGCGCAATGAGCGTCTCCAGATCGCCT
CGAACTTCGAGGCCACCATGGGCGCGCTCGCCCGTGCCTTCGCCCAGTCCTCGCAGGAGATGTCAGAAGCCGCCCGCAGC
CTCGCGGCGACCGCCGAGGAAACCTCCCGTCAGGCGGAAGCCGTGGGCGGGGCGGCGGAGGAAGCCAGCACCAATGTGAG
CACGGTTGCCGCCTCCACCGAGGAGATGACCGCCTCCATCCGCGAGATCGCGGCGCAGGTGACCCAGACGGCCACCATCG
CCACGGCCGCCGCCAGCGAAACCGCCCGCACCCAGACGGAGATCATCGAGCTCTCCCAGTCGGCGGCCAAGATCGGCGAA
GTGGTGGATCTCATCACCAACATCGCCAGCCAGACCAACCTGCTGGCGCTCAATGCCACCATCGAGGCGGCGCGCGCCGG
CGAGATGGGCAAGGGCTTTGCCGTCGTGGCGCAGGAGGTGAAGCAGCTCGCCGCCCAGACCGCCAAGGCCACCGAGGAAA
TCGCCGGCAAGGTGGGCGAGATCCAGCAGGCCACCAACCGCTCGGTGGAATCCATCGACCGCATCGTGACCACCATCGGC
CAGATCCAGACGGCGGCCTCCACCGTCGCCTCCGCGGTCGAGGAACAGGGCGCCGCCACCGCCGAGATCGCCAGCAACAC
CCAGCAGGCGGCGCGCGGGACGGAGACGGTGAACCACAACATCGCCGGCGTCGGCCGCGCCGCCGAGATGACCGGCGCCG
CTTCCAGCCAGCTCATGACGCTGTCCCAGTCCATCACCAGCCAGGCCCAGCAGCTCAAGCTGGAAGTGGAACAGGTGGTG
GCGAACCTGCGCGCCGGCTAA

Upstream 100 bases:

>100_bases
CTCGCGACGCATTTCGAGCGCGGCCAACGGCGCACGCTCCTGATACCGCAGCGTCAGTGTCGCCCCATTCGGGTCGGCAA
ACGGTCAAGGAGGGGGAACC

Downstream 100 bases:

>100_bases
GCCCCCAGCCAACCGCAGTGAGGAAGGGCTCCGTGCCTCGCGCACGGGGCTCTTTTCACGCCTTGCGGCAATTGGGCCCA
TGACAGGCGATTACAAGGCT

Product: histidine kinase

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MSFKNMPIMLKIGVVILLLGACAIGGTFIAGSKVASVSESYQGAIKDDAGFLQLARLNRQVVGVQRSIYQLVIAEAPEEV
KTAEDRLTSTINLLDTRVKDAKALLPKLSGQIDQIASDIKGALAGSACGPTIKAARETSGAEAIVKAGRMMVNECDPVLR
GSVESITKLIDAAVIENKKSLSELEAATASTIMSLNIVMGLAVFVSLVIAGLVARFGIVKPINGLLAVMTQIQSGNLSVT
VPDTERRDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIASNFEATMGALARAFAQSSQEMSEAARS
LAATAEETSRQAEAVGGAAEEASTNVSTVAASTEEMTASIREIAAQVTQTATIATAAASETARTQTEIIELSQSAAKIGE
VVDLITNIASQTNLLALNATIEAARAGEMGKGFAVVAQEVKQLAAQTAKATEEIAGKVGEIQQATNRSVESIDRIVTTIG
QIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAASSQLMTLSQSITSQAQQLKLEVEQVV
ANLRAG

Sequences:

>Translated_566_residues
MSFKNMPIMLKIGVVILLLGACAIGGTFIAGSKVASVSESYQGAIKDDAGFLQLARLNRQVVGVQRSIYQLVIAEAPEEV
KTAEDRLTSTINLLDTRVKDAKALLPKLSGQIDQIASDIKGALAGSACGPTIKAARETSGAEAIVKAGRMMVNECDPVLR
GSVESITKLIDAAVIENKKSLSELEAATASTIMSLNIVMGLAVFVSLVIAGLVARFGIVKPINGLLAVMTQIQSGNLSVT
VPDTERRDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIASNFEATMGALARAFAQSSQEMSEAARS
LAATAEETSRQAEAVGGAAEEASTNVSTVAASTEEMTASIREIAAQVTQTATIATAAASETARTQTEIIELSQSAAKIGE
VVDLITNIASQTNLLALNATIEAARAGEMGKGFAVVAQEVKQLAAQTAKATEEIAGKVGEIQQATNRSVESIDRIVTTIG
QIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAASSQLMTLSQSITSQAQQLKLEVEQVV
ANLRAG
>Mature_565_residues
SFKNMPIMLKIGVVILLLGACAIGGTFIAGSKVASVSESYQGAIKDDAGFLQLARLNRQVVGVQRSIYQLVIAEAPEEVK
TAEDRLTSTINLLDTRVKDAKALLPKLSGQIDQIASDIKGALAGSACGPTIKAARETSGAEAIVKAGRMMVNECDPVLRG
SVESITKLIDAAVIENKKSLSELEAATASTIMSLNIVMGLAVFVSLVIAGLVARFGIVKPINGLLAVMTQIQSGNLSVTV
PDTERRDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIASNFEATMGALARAFAQSSQEMSEAARSL
AATAEETSRQAEAVGGAAEEASTNVSTVAASTEEMTASIREIAAQVTQTATIATAAASETARTQTEIIELSQSAAKIGEV
VDLITNIASQTNLLALNATIEAARAGEMGKGFAVVAQEVKQLAAQTAKATEEIAGKVGEIQQATNRSVESIDRIVTTIGQ
IQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAASSQLMTLSQSITSQAQQLKLEVEQVVA
NLRAG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=373, Percent_Identity=28.9544235924933, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788194, Length=337, Percent_Identity=30.5637982195846, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788195, Length=319, Percent_Identity=27.8996865203762, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787690, Length=237, Percent_Identity=33.7552742616034, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789453, Length=117, Percent_Identity=41.8803418803419, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59012; Mature: 58881

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKNMPIMLKIGVVILLLGACAIGGTFIAGSKVASVSESYQGAIKDDAGFLQLARLNRQ
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VVGVQRSIYQLVIAEAPEEVKTAEDRLTSTINLLDTRVKDAKALLPKLSGQIDQIASDIK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GALAGSACGPTIKAARETSGAEAIVKAGRMMVNECDPVLRGSVESITKLIDAAVIENKKS
HHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCHHH
LSELEAATASTIMSLNIVMGLAVFVSLVIAGLVARFGIVKPINGLLAVMTQIQSGNLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEE
VPDTERRDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIASNFEATM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALARAFAQSSQEMSEAARSLAATAEETSRQAEAVGGAAEEASTNVSTVAASTEEMTASI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHH
REIAAQVTQTATIATAAASETARTQTEIIELSQSAAKIGEVVDLITNIASQTNLLALNAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECH
IEAARAGEMGKGFAVVAQEVKQLAAQTAKATEEIAGKVGEIQQATNRSVESIDRIVTTIG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAASSQLMT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHCCHHHHHHH
LSQSITSQAQQLKLEVEQVVANLRAG
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFKNMPIMLKIGVVILLLGACAIGGTFIAGSKVASVSESYQGAIKDDAGFLQLARLNRQ
CCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VVGVQRSIYQLVIAEAPEEVKTAEDRLTSTINLLDTRVKDAKALLPKLSGQIDQIASDIK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GALAGSACGPTIKAARETSGAEAIVKAGRMMVNECDPVLRGSVESITKLIDAAVIENKKS
HHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCHHH
LSELEAATASTIMSLNIVMGLAVFVSLVIAGLVARFGIVKPINGLLAVMTQIQSGNLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEE
VPDTERRDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIASNFEATM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALARAFAQSSQEMSEAARSLAATAEETSRQAEAVGGAAEEASTNVSTVAASTEEMTASI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHH
REIAAQVTQTATIATAAASETARTQTEIIELSQSAAKIGEVVDLITNIASQTNLLALNAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECH
IEAARAGEMGKGFAVVAQEVKQLAAQTAKATEEIAGKVGEIQQATNRSVESIDRIVTTIG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAASSQLMT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHCCHHHHHHH
LSQSITSQAQQLKLEVEQVVANLRAG
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]