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The map label for this gene is pcm2 [H]

Identifier: 158424442

GI number: 158424442

Start: 3206513

End: 3207184

Strand: Reverse

Name: pcm2 [H]

Synonym: AZC_2818

Alternate gene names: 158424442

Gene position: 3207184-3206513 (Counterclockwise)

Preceding gene: 158424443

Following gene: 158424441

Centisome position: 59.73

GC content: 68.3

Gene sequence:

>672_bases
ATGGTCGATTACGCGGAACTGCGCCGGGGGATGGTCGATTCCCAGGTGCGCGCCAATGACGTGACGGATCTGCGCATCGT
GGCCGCCATGATGGAGATGCCGCGCGAGCGCTTCGTTCCCGCCAACCTCAAGTCGCTGGCCTATATCGACGAGGATCTGG
TGATCCGCGCCGCGACCGCCCAGCAGCCGGCCCGCTATCTGATCGAGCCGATGGTGCTCGCCAAGCTGATTCAGCTCGCC
GACGTGCAGGCCGACGAGATCGTGCTCGATGTGGCCGCCGGCACCGGCTATTCGGCCGCCGTCCTCGCCCGCCTCTCGCA
GCAGGTGGTGGCGCTGGAGGATGATGCCGACCTCGTCGCCGCCGCCAACGCCGTGCTGAGCGAACTGGCCATCACCAACG
TCGCCGTCCTCAAGGGACCGCTCACCGCCGGCTGGGCAGCCGAGGGGCCTTACGACGTGATTCTTCTCAACGGCGCCGTG
GATGTGGTGCCGCAGGCCCTGTTCGACCAGCTCAAGGACGGCGGTCGCCTCGTGGCGGTGGTCGGCCGGGGCGGTGCGGC
CCATGCGGTGATCTACACCAAGGTGGGCGGTGCGGTGTCCGAGCGGGTGGTGTTCAACGCCTCCGTGCCCACGCTGCCGG
GCTTCGAGGCGCCGCAGCGCTTCACTTTCTAG

Upstream 100 bases:

>100_bases
CCGGTTCGGCTCTGAAGCGCAGCCGCCGCCTTGCAAAAATGGCGGCGGTGTGGCTCTTGAGTCCGAAACATGGCTCGCCG
GGATGTGGCGGAGGATTACG

Downstream 100 bases:

>100_bases
GCTCTGCGCCGTGTCGCGCGGCGGCGGAACGGACCTGTGTCCGATCTGCCGCGGTGCGCCAAAAAACAATTGGTTATCGA
ACCGGTCGGTTTTCTCGTCT

Product: methyltransferase transmembrane protein

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase 2; Protein L-isoaspartyl methyltransferase 2; Protein-beta-aspartate methyltransferase 2; PIMT 2 [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MVDYAELRRGMVDSQVRANDVTDLRIVAAMMEMPRERFVPANLKSLAYIDEDLVIRAATAQQPARYLIEPMVLAKLIQLA
DVQADEIVLDVAAGTGYSAAVLARLSQQVVALEDDADLVAAANAVLSELAITNVAVLKGPLTAGWAAEGPYDVILLNGAV
DVVPQALFDQLKDGGRLVAVVGRGGAAHAVIYTKVGGAVSERVVFNASVPTLPGFEAPQRFTF

Sequences:

>Translated_223_residues
MVDYAELRRGMVDSQVRANDVTDLRIVAAMMEMPRERFVPANLKSLAYIDEDLVIRAATAQQPARYLIEPMVLAKLIQLA
DVQADEIVLDVAAGTGYSAAVLARLSQQVVALEDDADLVAAANAVLSELAITNVAVLKGPLTAGWAAEGPYDVILLNGAV
DVVPQALFDQLKDGGRLVAVVGRGGAAHAVIYTKVGGAVSERVVFNASVPTLPGFEAPQRFTF
>Mature_223_residues
MVDYAELRRGMVDSQVRANDVTDLRIVAAMMEMPRERFVPANLKSLAYIDEDLVIRAATAQQPARYLIEPMVLAKLIQLA
DVQADEIVLDVAAGTGYSAAVLARLSQQVVALEDDADLVAAANAVLSELAITNVAVLKGPLTAGWAAEGPYDVILLNGAV
DVVPQALFDQLKDGGRLVAVVGRGGAAHAVIYTKVGGAVSERVVFNASVPTLPGFEAPQRFTF

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789100, Length=168, Percent_Identity=31.547619047619, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 23644; Mature: 23644

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDYAELRRGMVDSQVRANDVTDLRIVAAMMEMPRERFVPANLKSLAYIDEDLVIRAATA
CCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHCCCCCEEEECCC
QQPARYLIEPMVLAKLIQLADVQADEIVLDVAAGTGYSAAVLARLSQQVVALEDDADLVA
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECCCCHHHH
AANAVLSELAITNVAVLKGPLTAGWAAEGPYDVILLNGAVDVVPQALFDQLKDGGRLVAV
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEE
VGRGGAAHAVIYTKVGGAVSERVVFNASVPTLPGFEAPQRFTF
EECCCCEEEEEEEECCCCHHCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVDYAELRRGMVDSQVRANDVTDLRIVAAMMEMPRERFVPANLKSLAYIDEDLVIRAATA
CCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHCCCCCEEEECCC
QQPARYLIEPMVLAKLIQLADVQADEIVLDVAAGTGYSAAVLARLSQQVVALEDDADLVA
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECCCCHHHH
AANAVLSELAITNVAVLKGPLTAGWAAEGPYDVILLNGAVDVVPQALFDQLKDGGRLVAV
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEE
VGRGGAAHAVIYTKVGGAVSERVVFNASVPTLPGFEAPQRFTF
EECCCCEEEEEEEECCCCHHCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA