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The map label for this gene is tolC [H]

Identifier: 158424441

GI number: 158424441

Start: 3204935

End: 3206476

Strand: Reverse

Name: tolC [H]

Synonym: AZC_2817

Alternate gene names: 158424441

Gene position: 3206476-3204935 (Counterclockwise)

Preceding gene: 158424442

Following gene: 158424440

Centisome position: 59.71

GC content: 65.76

Gene sequence:

>1542_bases
GTGTCCGATCTGCCGCGGTGCGCCAAAAAACAATTGGTTATCGAACCGGTCGGTTTTCTCGTCTGGTGTCGCTGGATATG
GTCTGAATTCAATCCGCGTGTCTGGCTTTCAGATACAGCTCGGGGCGGAGCCGCGGTTCGGGAGAACTCAATGTCGCTTG
CGACGCATTTTTGCCGACGCCTGTCAGTTCTTGCTGCGGCGGCCGTAGTCTCCGGTCTGGCATGGACCTCCAGCGTGTCC
GCCCAAACCCTCGAGACGGCGCTCGGACAGGCTTACGTCAACAACCCCAGCCTCAACTCGCAGCGCGCCGGCACCCGTGC
CACGGACGAAAGCGTGCCGCAGGCCCTGTCGGGCTATCGTCCGAACGTGTCCGCCGGTGCCAGCGTGGGCGGGCAGTATG
CCCGCACCAATTCGTCCGGGACGATCGCGACCAACTCGCTCGTGCCGCGTTCGGTGAACCTCACGGTCTCGCAGACCATC
TTCAACGGCTTCCTCACCGCCAGCACCACCCAGAAGGCGGAGTCGTCCGTCAAGGGCTCGCGGGAGACCCTGCGCAACAC
CGAGCAGACCATCCTGCTCAACGCGGTGACGGCCTATATGAACGTCCTGCAGGGCATTGCCCTGCTGGAGTTGCAGAATC
AGAACCTCGCCGCGTTGCAGCAGGAACTGCGGGCGACCCGCGACCGCTTCAATGTGGGTGAGGTGACCCGCACCGACGTG
GCGCAGGCCGAGGCGCAGGTGGCCACGGCCAACTATCAGGTGGCCCAGGCGGTCGCGAATCTGCAGGCCTACAAGGCCAC
CTACCGCCAGGTGATCGGTGTGGAGCCGGGCAAGCTGACGGCGCCCAAGTCCATCGAGTTCATGCTGCCGCCCACCGTCG
ACAAGGCCGTCGCGGCCGGCCTGTCCACGCACCCGGCCATCCAGGCGTCCAAGTTCGCCGTCGATGCGGCCATGTTCCAG
GTGAAGATGTCCGAGGCGGGCCTCGCGCCCGTGGTCAGCGTTCAGGGCCAGCTCGCCCAGGGCTATGACCAGAACAGCGC
GGTGGACAGCACCAGCTCGGCCTCAGTGGCGCTGAACCTGACGGTGCCGATCTATCAGGGCGGCGCCGAATATTCCGCCA
TCCGCCAGTCCAAGGAACTGCTCACGCAGGCCCGCATCGAGGTGGACGTGAACCGCGATACGGTGCGCGCCAACACGGTG
CAGTACTGGGGCGCGCTGGAAGCCGCGAAGGCGCAGATCCAGTCGGCCCAGGCCTCCGTTGCCGCCAACACGCTGGCGCT
CGAAGGCGTCCGCGAAGAGTGGCGCGTGGGCCAGCGCACCACCACCGACGTGCTGAACGCCCAGACCGATCTCACCACCT
CCAAGTCCAACCTCGTGACGGCGCAGCGCGACCGTGTGGTGGCGGCCTACTCGCTGCTCTCCTCCGTCGGCAAGCTGGAT
GCGGTGACGCTGGGCCTGAAGGTGCCGGTCTATGATGCCCGCGTGCACTATGATCAGGTGCGCGATGCCTGGGCTGGCAT
CCGGACGCCGGACGGTAAATAA

Upstream 100 bases:

>100_bases
GGTGTTCAACGCCTCCGTGCCCACGCTGCCGGGCTTCGAGGCGCCGCAGCGCTTCACTTTCTAGGCTCTGCGCCGTGTCG
CGCGGCGGCGGAACGGACCT

Downstream 100 bases:

>100_bases
TAATTAACCCTTGGATGGCCGGCCCCCAATCTGTTGTGGTGGTCCGGTGCCATGACATACTTCGACCTTAGGTGGCGATT
CTGACGTCCATGAAAAAGCT

Product: type I secretion outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MSDLPRCAKKQLVIEPVGFLVWCRWIWSEFNPRVWLSDTARGGAAVRENSMSLATHFCRRLSVLAAAAVVSGLAWTSSVS
AQTLETALGQAYVNNPSLNSQRAGTRATDESVPQALSGYRPNVSAGASVGGQYARTNSSGTIATNSLVPRSVNLTVSQTI
FNGFLTASTTQKAESSVKGSRETLRNTEQTILLNAVTAYMNVLQGIALLELQNQNLAALQQELRATRDRFNVGEVTRTDV
AQAEAQVATANYQVAQAVANLQAYKATYRQVIGVEPGKLTAPKSIEFMLPPTVDKAVAAGLSTHPAIQASKFAVDAAMFQ
VKMSEAGLAPVVSVQGQLAQGYDQNSAVDSTSSASVALNLTVPIYQGGAEYSAIRQSKELLTQARIEVDVNRDTVRANTV
QYWGALEAAKAQIQSAQASVAANTLALEGVREEWRVGQRTTTDVLNAQTDLTTSKSNLVTAQRDRVVAAYSLLSSVGKLD
AVTLGLKVPVYDARVHYDQVRDAWAGIRTPDGK

Sequences:

>Translated_513_residues
MSDLPRCAKKQLVIEPVGFLVWCRWIWSEFNPRVWLSDTARGGAAVRENSMSLATHFCRRLSVLAAAAVVSGLAWTSSVS
AQTLETALGQAYVNNPSLNSQRAGTRATDESVPQALSGYRPNVSAGASVGGQYARTNSSGTIATNSLVPRSVNLTVSQTI
FNGFLTASTTQKAESSVKGSRETLRNTEQTILLNAVTAYMNVLQGIALLELQNQNLAALQQELRATRDRFNVGEVTRTDV
AQAEAQVATANYQVAQAVANLQAYKATYRQVIGVEPGKLTAPKSIEFMLPPTVDKAVAAGLSTHPAIQASKFAVDAAMFQ
VKMSEAGLAPVVSVQGQLAQGYDQNSAVDSTSSASVALNLTVPIYQGGAEYSAIRQSKELLTQARIEVDVNRDTVRANTV
QYWGALEAAKAQIQSAQASVAANTLALEGVREEWRVGQRTTTDVLNAQTDLTTSKSNLVTAQRDRVVAAYSLLSSVGKLD
AVTLGLKVPVYDARVHYDQVRDAWAGIRTPDGK
>Mature_512_residues
SDLPRCAKKQLVIEPVGFLVWCRWIWSEFNPRVWLSDTARGGAAVRENSMSLATHFCRRLSVLAAAAVVSGLAWTSSVSA
QTLETALGQAYVNNPSLNSQRAGTRATDESVPQALSGYRPNVSAGASVGGQYARTNSSGTIATNSLVPRSVNLTVSQTIF
NGFLTASTTQKAESSVKGSRETLRNTEQTILLNAVTAYMNVLQGIALLELQNQNLAALQQELRATRDRFNVGEVTRTDVA
QAEAQVATANYQVAQAVANLQAYKATYRQVIGVEPGKLTAPKSIEFMLPPTVDKAVAAGLSTHPAIQASKFAVDAAMFQV
KMSEAGLAPVVSVQGQLAQGYDQNSAVDSTSSASVALNLTVPIYQGGAEYSAIRQSKELLTQARIEVDVNRDTVRANTVQ
YWGALEAAKAQIQSAQASVAANTLALEGVREEWRVGQRTTTDVLNAQTDLTTSKSNLVTAQRDRVVAAYSLLSSVGKLDA
VTLGLKVPVYDARVHYDQVRDAWAGIRTPDGK

Specific function: Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=421, Percent_Identity=26.1282660332542, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54884; Mature: 54753

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPRCAKKQLVIEPVGFLVWCRWIWSEFNPRVWLSDTARGGAAVRENSMSLATHFCRR
CCCCCHHHHHCEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCHHHHHHHHHHH
LSVLAAAAVVSGLAWTSSVSAQTLETALGQAYVNNPSLNSQRAGTRATDESVPQALSGYR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCC
PNVSAGASVGGQYARTNSSGTIATNSLVPRSVNLTVSQTIFNGFLTASTTQKAESSVKGS
CCCCCCCCCCCCCEEECCCCCEEECCCCCCEECEEEHHHHHHHHHCCCCHHHHHHHHCCC
RETLRNTEQTILLNAVTAYMNVLQGIALLELQNQNLAALQQELRATRDRFNVGEVTRTDV
HHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHH
AQAEAQVATANYQVAQAVANLQAYKATYRQVIGVEPGKLTAPKSIEFMLPPTVDKAVAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHCC
LSTHPAIQASKFAVDAAMFQVKMSEAGLAPVVSVQGQLAQGYDQNSAVDSTSSASVALNL
CCCCCCCHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHCCCCCCCCCCCCCCCEEEEEE
TVPIYQGGAEYSAIRQSKELLTQARIEVDVNRDTVRANTVQYWGALEAAKAQIQSAQASV
EEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
AANTLALEGVREEWRVGQRTTTDVLNAQTDLTTSKSNLVTAQRDRVVAAYSLLSSVGKLD
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCC
AVTLGLKVPVYDARVHYDQVRDAWAGIRTPDGK
EEEEEEEECEEECHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDLPRCAKKQLVIEPVGFLVWCRWIWSEFNPRVWLSDTARGGAAVRENSMSLATHFCRR
CCCCHHHHHCEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCHHHHHHHHHHH
LSVLAAAAVVSGLAWTSSVSAQTLETALGQAYVNNPSLNSQRAGTRATDESVPQALSGYR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCC
PNVSAGASVGGQYARTNSSGTIATNSLVPRSVNLTVSQTIFNGFLTASTTQKAESSVKGS
CCCCCCCCCCCCCEEECCCCCEEECCCCCCEECEEEHHHHHHHHHCCCCHHHHHHHHCCC
RETLRNTEQTILLNAVTAYMNVLQGIALLELQNQNLAALQQELRATRDRFNVGEVTRTDV
HHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHH
AQAEAQVATANYQVAQAVANLQAYKATYRQVIGVEPGKLTAPKSIEFMLPPTVDKAVAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHCC
LSTHPAIQASKFAVDAAMFQVKMSEAGLAPVVSVQGQLAQGYDQNSAVDSTSSASVALNL
CCCCCCCHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHCCCCCCCCCCCCCCCEEEEEE
TVPIYQGGAEYSAIRQSKELLTQARIEVDVNRDTVRANTVQYWGALEAAKAQIQSAQASV
EEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
AANTLALEGVREEWRVGQRTTTDVLNAQTDLTTSKSNLVTAQRDRVVAAYSLLSSVGKLD
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCC
AVTLGLKVPVYDARVHYDQVRDAWAGIRTPDGK
EEEEEEEECEEECHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]