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The map label for this gene is iorA [H]

Identifier: 158424424

GI number: 158424424

Start: 3181560

End: 3182054

Strand: Direct

Name: iorA [H]

Synonym: AZC_2800

Alternate gene names: 158424424

Gene position: 3181560-3182054 (Clockwise)

Preceding gene: 158424413

Following gene: 158424425

Centisome position: 59.25

GC content: 68.48

Gene sequence:

>495_bases
ATGGCGGATGAGGTTGCCTTCACCGTGAACGGCGTGCCGCACGGCTTCGCGCTGCCGCGTGAGACCCCGCTCATTTATGT
GCTGCGCAACGATCTCGGCCTCAACGGCCCCAAGTTCGGCTGCGGCCTTGGCGAATGCGGCGCCTGCACGGTGCTGGTGG
ACGGGGTGGCGGCGCGTTCCTGCGTCACCAAGCTCGCCAGCGTGGAGGGCCGCGCGGTGACGACGCTGGAGGGCCTTGGC
ACGCTGGCCGCCCCGCATCCGGTACAGGCCGCCTTCATCGCCGAACAGGGCGCCCAGTGCGGCTATTGTCTCAACGGCAT
GATAATGACGACAGTCGCCTTTCTGAAGCGCAACCCCAGCCCCACCGAGGCCGAGGCCCGCGAAGCGCTACGCTACAATC
TCTGCCGCTGCGGGACGCACGTGGAAATCCTGCGCTCCGTGCTGCGCGCCGCAAGCGACATGGCCGCCGCGCCAGAGACG
AGCGTGGCGCCATGA

Upstream 100 bases:

>100_bases
CCAGCCAGAGGGGCGGACATGATCGCGAACCCACAGCGCGCGGCGGGCCTTGCGGCCTGCGGCGCCCGTTGTCGTTTGTC
CGGCCCGGAGCGGGCGCGAC

Downstream 100 bases:

>100_bases
CCGAGCCGGCGCCTTCCCCCGACGCTCTGCTCGCCCGCGCCGGCACGCTCGCCATCCTGCGCCCGGCGCAGCATGTGAAG
GGCCTCGTGCCCACCGCCCC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MADEVAFTVNGVPHGFALPRETPLIYVLRNDLGLNGPKFGCGLGECGACTVLVDGVAARSCVTKLASVEGRAVTTLEGLG
TLAAPHPVQAAFIAEQGAQCGYCLNGMIMTTVAFLKRNPSPTEAEAREALRYNLCRCGTHVEILRSVLRAASDMAAAPET
SVAP

Sequences:

>Translated_164_residues
MADEVAFTVNGVPHGFALPRETPLIYVLRNDLGLNGPKFGCGLGECGACTVLVDGVAARSCVTKLASVEGRAVTTLEGLG
TLAAPHPVQAAFIAEQGAQCGYCLNGMIMTTVAFLKRNPSPTEAEAREALRYNLCRCGTHVEILRSVLRAASDMAAAPET
SVAP
>Mature_163_residues
ADEVAFTVNGVPHGFALPRETPLIYVLRNDLGLNGPKFGCGLGECGACTVLVDGVAARSCVTKLASVEGRAVTTLEGLGT
LAAPHPVQAAFIAEQGAQCGYCLNGMIMTTVAFLKRNPSPTEAEAREALRYNLCRCGTHVEILRSVLRAASDMAAAPETS
VAP

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=40.7643312101911, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI71773480, Length=88, Percent_Identity=40.9090909090909, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=38.9221556886228, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=42.4657534246575, Blast_Score=98, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=164, Percent_Identity=38.4146341463415, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=137, Percent_Identity=37.956204379562, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=143, Percent_Identity=35.6643356643357, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=38.1578947368421, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=32.9268292682927, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=32.9268292682927, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=33.9506172839506, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=32.6923076923077, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=31.4102564102564, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17090; Mature: 16959

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEVAFTVNGVPHGFALPRETPLIYVLRNDLGLNGPKFGCGLGECGACTVLVDGVAARS
CCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CVTKLASVEGRAVTTLEGLGTLAAPHPVQAAFIAEQGAQCGYCLNGMIMTTVAFLKRNPS
HHHHHHHCCCCEEEHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
PTEAEAREALRYNLCRCGTHVEILRSVLRAASDMAAAPETSVAP
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADEVAFTVNGVPHGFALPRETPLIYVLRNDLGLNGPKFGCGLGECGACTVLVDGVAARS
CCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CVTKLASVEGRAVTTLEGLGTLAAPHPVQAAFIAEQGAQCGYCLNGMIMTTVAFLKRNPS
HHHHHHHCCCCEEEHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
PTEAEAREALRYNLCRCGTHVEILRSVLRAASDMAAAPETSVAP
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]