Click here to switch to the map view.

The map label for this gene is ppdK [H]

Identifier: 158424387

GI number: 158424387

Start: 3141791

End: 3143386

Strand: Reverse

Name: ppdK [H]

Synonym: AZC_2763

Alternate gene names: 158424387

Gene position: 3143386-3141791 (Counterclockwise)

Preceding gene: 158424388

Following gene: 158424385

Centisome position: 58.54

GC content: 71.87

Gene sequence:

>1596_bases
ATGCGCATCGTACGCATCGCCCCCGACATGACCGACCTGCCGAGCGCGGAACAGGTGGGCGCGAAGGCCGCCAATCTCGC
GCGCATGGCCGCGCTGGGGCTGCCCGTTCCCCCGGCGTTCGTGCTGCCGGTAAGCCTGTGCGCGGCGACCGTGGCCGGCG
AGCCCAAGGCCCGCAAGGCGCTGGAAGAGGGGCTCGGCGAGGGCATCGCCTTCCTGGAGGAGCGCACCGGACGGCGGTTC
GGTGATGGCCGGCAGCCGCTGCTGGTGTCCGTGCGCTCGGGGGCGGCGCGCTCCATGCCGGGCATGCTGGAGACGGTGCT
GGACGTGGGATGCACGCGCCTCGCGACGCAGGGCCTCATCCGCATGACCGGGCATCCGCGCTTCGCCTGGGACTGCCGCC
GCCGCTTTCTCGAAAGCTACGGGAGCGTGGTCCTGAACATCGATCCGCACGGCTTCGATCGCGCCGCCGCCGCCCTCGCG
GCGGCGGAAGGGCTGCCTGATGCCCTCGACCTTGACGGCGAAGCGCTGGAGCGGCTCTCGGAGACCTACCAGCACTTCAT
CGAGGAGGCGGACGAGAGCGTGCCGGACGCGCCGATGGAGCAGGTGCTGGCTGCGGCGCAGGCCGTCTATCGCTCCTGGA
TGAGTCCGCGCGCGGTGGCCTACCGGCGCATCGAGCGGCTGGAGCATCTGGCGGGAACGGCCGTGACCGTGCAGGCGATG
GTCTATGGCAATCGGGGCCTGACATCGGGCGCGGGCGTTGCCTTCTCCCGCAACCCCTCCACCGGCGATGCCGCGCCCAT
GATCGACGTCCTGCTCTCGGCGCAGGGCGAGGAGGTCGTTTCCGGCAGCCGCACCCCGCTCGGGGAGGAGGTGCTGCGTG
CGGCGGTGCCCGAGGCGGCGGCGGAACTGCGCGACGTGCTGGCGCGGCTGGAACGGGCCTTCGGCGACGTGCAGGACGTG
GAGTTCACCGTGGAGGACGGGCGGCTCTTCATCCTCCAGACCCGTAACGCCAAGCGGACGCCGCAGGCCGCGTTGCGCAT
CGCCGTCGCGCTGGTGGAGGAAGGCCTCATCACGCCGCACGAGGCGCTCGCGCGGCTCGACGACCTCGACATGGATGTGC
TCAGCGAGACGCACCTGGCCGAGACGGGCGATCCCGCCGCATACGGGACCGGCGCCTCTACCGGTGTTGCCTGCGGGCGC
GTCGCCTTTTCTTCGGAGACGGCCCAGCGCATGGCCGGGGGCGGAGAGCCGGTCATCCTCGTGCGGCCGGATACCAGCAC
GGCGGATGTCACGGGTTTCTCGGTGGCGAGCGGCATCCTGACGGCGGTGGGTGGCCGCACGGCTCATGCCGCGCTGGTGG
CGCGCCAGATGGGCAAGCCCAGCGTGGTGGGATGCGCCGCGCTCGTGATGGACGAGGCGGGGCATGTGGCACGCATCGCG
GGGCAGGAGATTCACGAGGGCGACTGGCTCGCGCTCGATGGCGGCACCGGAGCGATATATACCGGCCGTTTCGAGATCGT
GACCTCACGCCCGGAGGCGGACCTTGCACAGGTCGCGGCCTGGCGGACGGCCGCGCCTGTCCCGGCCTGCGCCTGA

Upstream 100 bases:

>100_bases
AGCGCGCCACCGATCGGCTGGCGGGCTATGGCCACGCTCTGCGCGGCCACGTCCTTGCCGAGCTTGCGCTCTGATCCCCG
AAATCTGCGGAGACGCCATC

Downstream 100 bases:

>100_bases
AGGGAGAGCGCAGAAGCTGGGACGTAGGAACGGGTGCTGTCCGAGCACTGCTGCCTTATTGCTCGCAGCGGAACTGCACC
TCTGTCCAAATGGGGTGGCC

Product: pyruvate phosphate dikinase

Products: NA

Alternate protein names: Pyruvate, orthophosphate dikinase [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MRIVRIAPDMTDLPSAEQVGAKAANLARMAALGLPVPPAFVLPVSLCAATVAGEPKARKALEEGLGEGIAFLEERTGRRF
GDGRQPLLVSVRSGAARSMPGMLETVLDVGCTRLATQGLIRMTGHPRFAWDCRRRFLESYGSVVLNIDPHGFDRAAAALA
AAEGLPDALDLDGEALERLSETYQHFIEEADESVPDAPMEQVLAAAQAVYRSWMSPRAVAYRRIERLEHLAGTAVTVQAM
VYGNRGLTSGAGVAFSRNPSTGDAAPMIDVLLSAQGEEVVSGSRTPLGEEVLRAAVPEAAAELRDVLARLERAFGDVQDV
EFTVEDGRLFILQTRNAKRTPQAALRIAVALVEEGLITPHEALARLDDLDMDVLSETHLAETGDPAAYGTGASTGVACGR
VAFSSETAQRMAGGGEPVILVRPDTSTADVTGFSVASGILTAVGGRTAHAALVARQMGKPSVVGCAALVMDEAGHVARIA
GQEIHEGDWLALDGGTGAIYTGRFEIVTSRPEADLAQVAAWRTAAPVPACA

Sequences:

>Translated_531_residues
MRIVRIAPDMTDLPSAEQVGAKAANLARMAALGLPVPPAFVLPVSLCAATVAGEPKARKALEEGLGEGIAFLEERTGRRF
GDGRQPLLVSVRSGAARSMPGMLETVLDVGCTRLATQGLIRMTGHPRFAWDCRRRFLESYGSVVLNIDPHGFDRAAAALA
AAEGLPDALDLDGEALERLSETYQHFIEEADESVPDAPMEQVLAAAQAVYRSWMSPRAVAYRRIERLEHLAGTAVTVQAM
VYGNRGLTSGAGVAFSRNPSTGDAAPMIDVLLSAQGEEVVSGSRTPLGEEVLRAAVPEAAAELRDVLARLERAFGDVQDV
EFTVEDGRLFILQTRNAKRTPQAALRIAVALVEEGLITPHEALARLDDLDMDVLSETHLAETGDPAAYGTGASTGVACGR
VAFSSETAQRMAGGGEPVILVRPDTSTADVTGFSVASGILTAVGGRTAHAALVARQMGKPSVVGCAALVMDEAGHVARIA
GQEIHEGDWLALDGGTGAIYTGRFEIVTSRPEADLAQVAAWRTAAPVPACA
>Mature_531_residues
MRIVRIAPDMTDLPSAEQVGAKAANLARMAALGLPVPPAFVLPVSLCAATVAGEPKARKALEEGLGEGIAFLEERTGRRF
GDGRQPLLVSVRSGAARSMPGMLETVLDVGCTRLATQGLIRMTGHPRFAWDCRRRFLESYGSVVLNIDPHGFDRAAAALA
AAEGLPDALDLDGEALERLSETYQHFIEEADESVPDAPMEQVLAAAQAVYRSWMSPRAVAYRRIERLEHLAGTAVTVQAM
VYGNRGLTSGAGVAFSRNPSTGDAAPMIDVLLSAQGEEVVSGSRTPLGEEVLRAAVPEAAAELRDVLARLERAFGDVQDV
EFTVEDGRLFILQTRNAKRTPQAALRIAVALVEEGLITPHEALARLDDLDMDVLSETHLAETGDPAAYGTGASTGVACGR
VAFSSETAQRMAGGGEPVILVRPDTSTADVTGFSVASGILTAVGGRTAHAALVARQMGKPSVVGCAALVMDEAGHVARIA
GQEIHEGDWLALDGGTGAIYTGRFEIVTSRPEADLAQVAAWRTAAPVPACA

Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR010121
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.1 [H]

Molecular weight: Translated: 55800; Mature: 55800

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVRIAPDMTDLPSAEQVGAKAANLARMAALGLPVPPAFVLPVSLCAATVAGEPKARKA
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHH
LEEGLGEGIAFLEERTGRRFGDGRQPLLVSVRSGAARSMPGMLETVLDVGCTRLATQGLI
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHH
RMTGHPRFAWDCRRRFLESYGSVVLNIDPHGFDRAAAALAAAEGLPDALDLDGEALERLS
EECCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ETYQHFIEEADESVPDAPMEQVLAAAQAVYRSWMSPRAVAYRRIERLEHLAGTAVTVQAM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEE
VYGNRGLTSGAGVAFSRNPSTGDAAPMIDVLLSAQGEEVVSGSRTPLGEEVLRAAVPEAA
EECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHH
AELRDVLARLERAFGDVQDVEFTVEDGRLFILQTRNAKRTPQAALRIAVALVEEGLITPH
HHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHH
EALARLDDLDMDVLSETHLAETGDPAAYGTGASTGVACGRVAFSSETAQRMAGGGEPVIL
HHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCCCEEEE
VRPDTSTADVTGFSVASGILTAVGGRTAHAALVARQMGKPSVVGCAALVMDEAGHVARIA
ECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHHC
GQEIHEGDWLALDGGTGAIYTGRFEIVTSRPEADLAQVAAWRTAAPVPACA
CCCCCCCCEEEEECCCCEEEECEEEEEECCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRIVRIAPDMTDLPSAEQVGAKAANLARMAALGLPVPPAFVLPVSLCAATVAGEPKARKA
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHH
LEEGLGEGIAFLEERTGRRFGDGRQPLLVSVRSGAARSMPGMLETVLDVGCTRLATQGLI
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHH
RMTGHPRFAWDCRRRFLESYGSVVLNIDPHGFDRAAAALAAAEGLPDALDLDGEALERLS
EECCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ETYQHFIEEADESVPDAPMEQVLAAAQAVYRSWMSPRAVAYRRIERLEHLAGTAVTVQAM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEE
VYGNRGLTSGAGVAFSRNPSTGDAAPMIDVLLSAQGEEVVSGSRTPLGEEVLRAAVPEAA
EECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHH
AELRDVLARLERAFGDVQDVEFTVEDGRLFILQTRNAKRTPQAALRIAVALVEEGLITPH
HHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHH
EALARLDDLDMDVLSETHLAETGDPAAYGTGASTGVACGRVAFSSETAQRMAGGGEPVIL
HHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCCCEEEE
VRPDTSTADVTGFSVASGILTAVGGRTAHAALVARQMGKPSVVGCAALVMDEAGHVARIA
ECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHHC
GQEIHEGDWLALDGGTGAIYTGRFEIVTSRPEADLAQVAAWRTAAPVPACA
CCCCCCCCEEEEECCCCEEEECEEEEEECCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2176881; 6257292; 11695893; 11468288; 8610096; 9753432 [H]