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The map label for this gene is hmp [H]

Identifier: 158424375

GI number: 158424375

Start: 3125905

End: 3127242

Strand: Reverse

Name: hmp [H]

Synonym: AZC_2751

Alternate gene names: 158424375

Gene position: 3127242-3125905 (Counterclockwise)

Preceding gene: 158424376

Following gene: 158424374

Centisome position: 58.24

GC content: 68.54

Gene sequence:

>1338_bases
ATGCAAAATACAAGGGAGGCGCTCGGAAGGTTGAGCGAGAGGCGGTTCGCCTCTGGCCGACGTTCCGGCGATCACGGCAT
GTCAATATTGTCCAGCGGATGGCGCGCGTTCACGGTTGCCGAACGGCACCCTGAGACGGCACAGATCACCTCCTTCCATC
TCGTGCCCGCCGATGGCGGGGCGCCCCCGGTGCACAAGGCCGGTCAGCACCTGACCCTGCGCCTCTCCGATCCGTCCCGG
CTGATCCGCAATTACACCATCTCCACCGCGCCCAACGGCCATCACTGGCGCATTTCGGTGAAGCGGGAAGGCGCGGCGTC
GACGTGGCTGCATGACGCGCTCCGGGTCGGCGACACGCTGGAGGTCGCCGGCCCCGGTGGCGATTTCGTGCTGCCGTCTT
CGGCCGAGCGTCCGCTGGTGCTGGTGAGCGCCGGCGTCGGCGTGACGCCCATGGTGGCCATGCTGGAAGAGGCGGTGGCT
CAGGGCTGGTCGGGGCCCCTGCATTTCATCCATTGCACGCGCGATGCCGCCCATCAGGCCTTCGCCGAACACGTGGCGGA
CCTTCTGGCGAAGCTGCCCGCCGGCCGCTCGGACATCTTCTATTCCCGCGCGCCCCAGGCGGGACTTGGGGCGAACCAGC
ATGGCGGTCGCGTGACGCTGGATTTCCTGCGCACCCAGACGCCCCTCGGCGATGCCGACTATTTCCTCTGCGGTCCGGCC
GATTTCCTGCGCGACATGGCCCGAGGGCTCCATGAGGCGGGTGTGGACCGCGCGCGCATCCATTACGAATTCTTCGGCCC
GCCGGAGGAGATCCTGGAAGAGGCTGCCAGCCCCACGACTCCCATCCCCGTGCGCCCCGCAGTGCCCCGCGCCCCCCAGC
CCGTGACGGACGAGACCATGAGCCTTGAAGACCAGTTGGGCCGCGCCCTTCTCGGCAGCGCCGCCGATGCGGTGGTGGCC
TGCGACCGCGACGGCATCATCACGCTCTGGAACCCGGGCGCCGAGCGCATCTTCGGCTTCACGCCGGAGGAGGCGGTGGG
GCAGTCGCTGGATATCATCATCCCCGAGCCGTTCCGCGCCCGCCATTGGGAGGGCTATCACGTCACGGTCGCCACCGGCG
AGAGCCGCTACGGCGCCGGCGATCTCCTCGCGGTGCCCGGCCTGCGCAAGGATGGGGGACGCATCTCCATCGAATTCACC
ATCGTCCTCCTGAAGGATGGGGCGGGGCAGGTCTCGGGCATGATCTCGTCCATCCGCGATGTCTCCCGCCGCTTCGAGGA
GACCAAGGCGCTGAAGAAGCGCGTGGCGGAACTGGAAAAGGCGGCGGGGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGCAGCGGACGCGCTTCGGCGCGTCCGCTGCACTTCGTGCCTGCGACACCGCCCCCTATCCGGGTCGGGTTGTTTCTTCG
CCGGCGGCTGTTACCCTTGT

Downstream 100 bases:

>100_bases
ACCCTCGCCTCCGGCAAGGGAAACTTTGCGGGCGCGGCAGCGTTTCAGTTCGGATGTCGAACCGCGCGAGCCCCCCATGC
AGCATGATTTTCACCCCGTC

Product: globin

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MQNTREALGRLSERRFASGRRSGDHGMSILSSGWRAFTVAERHPETAQITSFHLVPADGGAPPVHKAGQHLTLRLSDPSR
LIRNYTISTAPNGHHWRISVKREGAASTWLHDALRVGDTLEVAGPGGDFVLPSSAERPLVLVSAGVGVTPMVAMLEEAVA
QGWSGPLHFIHCTRDAAHQAFAEHVADLLAKLPAGRSDIFYSRAPQAGLGANQHGGRVTLDFLRTQTPLGDADYFLCGPA
DFLRDMARGLHEAGVDRARIHYEFFGPPEEILEEAASPTTPIPVRPAVPRAPQPVTDETMSLEDQLGRALLGSAADAVVA
CDRDGIITLWNPGAERIFGFTPEEAVGQSLDIIIPEPFRARHWEGYHVTVATGESRYGAGDLLAVPGLRKDGGRISIEFT
IVLLKDGAGQVSGMISSIRDVSRRFEETKALKKRVAELEKAAGAA

Sequences:

>Translated_445_residues
MQNTREALGRLSERRFASGRRSGDHGMSILSSGWRAFTVAERHPETAQITSFHLVPADGGAPPVHKAGQHLTLRLSDPSR
LIRNYTISTAPNGHHWRISVKREGAASTWLHDALRVGDTLEVAGPGGDFVLPSSAERPLVLVSAGVGVTPMVAMLEEAVA
QGWSGPLHFIHCTRDAAHQAFAEHVADLLAKLPAGRSDIFYSRAPQAGLGANQHGGRVTLDFLRTQTPLGDADYFLCGPA
DFLRDMARGLHEAGVDRARIHYEFFGPPEEILEEAASPTTPIPVRPAVPRAPQPVTDETMSLEDQLGRALLGSAADAVVA
CDRDGIITLWNPGAERIFGFTPEEAVGQSLDIIIPEPFRARHWEGYHVTVATGESRYGAGDLLAVPGLRKDGGRISIEFT
IVLLKDGAGQVSGMISSIRDVSRRFEETKALKKRVAELEKAAGAA
>Mature_445_residues
MQNTREALGRLSERRFASGRRSGDHGMSILSSGWRAFTVAERHPETAQITSFHLVPADGGAPPVHKAGQHLTLRLSDPSR
LIRNYTISTAPNGHHWRISVKREGAASTWLHDALRVGDTLEVAGPGGDFVLPSSAERPLVLVSAGVGVTPMVAMLEEAVA
QGWSGPLHFIHCTRDAAHQAFAEHVADLLAKLPAGRSDIFYSRAPQAGLGANQHGGRVTLDFLRTQTPLGDADYFLCGPA
DFLRDMARGLHEAGVDRARIHYEFFGPPEEILEEAASPTTPIPVRPAVPRAPQPVTDETMSLEDQLGRALLGSAADAVVA
CDRDGIITLWNPGAERIFGFTPEEAVGQSLDIIIPEPFRARHWEGYHVTVATGESRYGAGDLLAVPGLRKDGGRISIEFT
IVLLKDGAGQVSGMISSIRDVSRRFEETKALKKRVAELEKAAGAA

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=247, Percent_Identity=35.2226720647773, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1787658, Length=251, Percent_Identity=28.2868525896414, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788104, Length=242, Percent_Identity=25.6198347107438, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787098, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321673, Length=256, Percent_Identity=31.25, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 47930; Mature: 47930

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNTREALGRLSERRFASGRRSGDHGMSILSSGWRAFTVAERHPETAQITSFHLVPADGG
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCEEEEEEEEEECCCC
APPVHKAGQHLTLRLSDPSRLIRNYTISTAPNGHHWRISVKREGAASTWLHDALRVGDTL
CCCCCCCCCEEEEEECCHHHHHHHCEEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCEE
EVAGPGGDFVLPSSAERPLVLVSAGVGVTPMVAMLEEAVAQGWSGPLHFIHCTRDAAHQA
EEECCCCCEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
FAEHVADLLAKLPAGRSDIFYSRAPQAGLGANQHGGRVTLDFLRTQTPLGDADYFLCGPA
HHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCH
DFLRDMARGLHEAGVDRARIHYEFFGPPEEILEEAASPTTPIPVRPAVPRAPQPVTDETM
HHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
SLEDQLGRALLGSAADAVVACDRDGIITLWNPGAERIFGFTPEEAVGQSLDIIIPEPFRA
HHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHHEECCCCHHHHCCCEEEEECCCCCC
RHWEGYHVTVATGESRYGAGDLLAVPGLRKDGGRISIEFTIVLLKDGAGQVSGMISSIRD
CCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHH
VSRRFEETKALKKRVAELEKAAGAA
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNTREALGRLSERRFASGRRSGDHGMSILSSGWRAFTVAERHPETAQITSFHLVPADGG
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCEEEEEEEEEECCCC
APPVHKAGQHLTLRLSDPSRLIRNYTISTAPNGHHWRISVKREGAASTWLHDALRVGDTL
CCCCCCCCCEEEEEECCHHHHHHHCEEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCEE
EVAGPGGDFVLPSSAERPLVLVSAGVGVTPMVAMLEEAVAQGWSGPLHFIHCTRDAAHQA
EEECCCCCEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
FAEHVADLLAKLPAGRSDIFYSRAPQAGLGANQHGGRVTLDFLRTQTPLGDADYFLCGPA
HHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCH
DFLRDMARGLHEAGVDRARIHYEFFGPPEEILEEAASPTTPIPVRPAVPRAPQPVTDETM
HHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
SLEDQLGRALLGSAADAVVACDRDGIITLWNPGAERIFGFTPEEAVGQSLDIIIPEPFRA
HHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHHEECCCCHHHHCCCEEEEECCCCCC
RHWEGYHVTVATGESRYGAGDLLAVPGLRKDGGRISIEFTIVLLKDGAGQVSGMISSIRD
CCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHH
VSRRFEETKALKKRVAELEKAAGAA
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]