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The map label for this gene is hyuA [H]

Identifier: 158424352

GI number: 158424352

Start: 3097332

End: 3098885

Strand: Direct

Name: hyuA [H]

Synonym: AZC_2728

Alternate gene names: 158424352

Gene position: 3097332-3098885 (Clockwise)

Preceding gene: 158424351

Following gene: 158424356

Centisome position: 57.68

GC content: 69.76

Gene sequence:

>1554_bases
ATGCGGCGCATCGGCATCGACGTCGGCGGCACCAATACGGACGCCGTGCTCATCGACGGCACCACCGTCATCCATTCCGT
GAAGCGCGCCACCACAGCGGACGTGACCACGGGCATACTCGACGCCCTCGCGGCGCTGCGCCAGCATCCGGCGACGCGGG
GCAAGGTGGATGCGGTGGTCATCGGCACCACCCATTTCATCAATGCGGTGGTGCAGCGCCGCCACCTCCAGAAGGTCGCC
GCCATCCGGCTCGGAATGCCGGCGAGCGCCGCGCTGCCGCCCTTCTGCGACTGGCCGTCGGATCTCGGCACGCTGGTGAA
TGGCGAGGTCTTCATGCTCGAAGGCGGGCATGACTATGACGGCCGCCCCTTCATGCCGCTCGACACGGCAGGCGTGCGCA
CGGCCGCGCGGCGCATCCGGGACCAGGGCATCCGCTCGGTGGCCATCTCGGCCATCTTCTCCCCGCTCGATCCCAGCGGC
GAGGAACAGGCGCGGGACATTCTGCTGGAGGAATGCCCGGACATCGCCGTCACCCTCTCCCACGACCTCGGCCGCATCGG
CCTGCTGGAGCGGGAAAATGCGGCGCTGCTCAATGCCGCCCTGCGCGATCTTGCCGCCACCACCGTCTCGGCCTTCCGCA
AGGCCATTGCGGACAGCGGCATCGATGCCCCGCTCTACCTCACCCAGAATGACGGCACGGTCATGCAGGCGGAGGTGGCG
ACCCAGTTCCCGGTCATGAGCTTTGCCTCTGGCGCCACCAATTCCATGCGCGGCGCGGCGCATCTTTCCGGCCTCGAGGA
TGCCATGGTGGTGGATGTGGGCGGCACCACGTCCGACATCGGCCAGTTGCGCCACGGCTTCCCCCGCGAGGCCAATTCGG
TGGTGGAAGTCGGTGGCGTGCGCACCCTGTTCCGGATGCCGGACCTGCTCTCCATCGGGCTCGGCGGCGGCAGCCATGTG
GACCCGGACACGGGCCGCATCGGCCCGCTTTCGGTGGGCTACCGGCTGACGCAGGATGCCCTTGTCTTCGGCGGCACGCA
GCTCACCGCCACGGACATTGCGGTGGCCGCCGGCCTGCTGGACATCGGCGACCGCGCCCGCGTGCAGCATCTCTCCGCCG
GCCTCATCACGGCGGCGCTGGAGAATGCCCGCCAGCAGCTTGAGGACAATGTGGACCGCATGAAGACCGAGGCAGGCGAA
GTGCCGCTGCTGGCGGTCGGCGGCGGGGCCTTCCTCGCGCCCGAGAAGCTCACCGGCTGCTCGCAGATCGTCCGCGTGCC
CCATGGCGATTGCGCCAATGCGGTGGGCGCGGCCATCGCGCAGGTGAGCGGGGAGACCGATCAGGTGTTCCGCGATCTCT
CCCGCGATGCGGCCATCGAAGCGGCCCTCACCATCGCCCGCGACCGGGCGGTGGCGGCGGGTGCAGATCGCGACAGCCTC
AAGACCGTGGAAGTGGAAGACATGCCCATCGCTTACCTGCCCGGCAACGCCCTGCGCGTGCGGGCGCGGGTGGCAGGCGG
CATCGCAACGCCGGACGTGCGCGACGCGGCCTGA

Upstream 100 bases:

>100_bases
GACGCCCAAGGGTCTGGAGCATGTGGGCCCGCGCGCCTTCGGCTACGACCTCGATTTCCATTCCCTCTTCCAGCCGTCCG
AAGGACGGGGAGCCTGACCC

Downstream 100 bases:

>100_bases
GCCCAAAAATGGAGACGCCGGCAGCGGGATGGCTGCCGGCTTCTCCACTTCATCCGCTCGTCAGTCCTGCCGCACGTCCG
CGACGGCGCCGCCGGTGAGG

Product: hydantoinase A

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MRRIGIDVGGTNTDAVLIDGTTVIHSVKRATTADVTTGILDALAALRQHPATRGKVDAVVIGTTHFINAVVQRRHLQKVA
AIRLGMPASAALPPFCDWPSDLGTLVNGEVFMLEGGHDYDGRPFMPLDTAGVRTAARRIRDQGIRSVAISAIFSPLDPSG
EEQARDILLEECPDIAVTLSHDLGRIGLLERENAALLNAALRDLAATTVSAFRKAIADSGIDAPLYLTQNDGTVMQAEVA
TQFPVMSFASGATNSMRGAAHLSGLEDAMVVDVGGTTSDIGQLRHGFPREANSVVEVGGVRTLFRMPDLLSIGLGGGSHV
DPDTGRIGPLSVGYRLTQDALVFGGTQLTATDIAVAAGLLDIGDRARVQHLSAGLITAALENARQQLEDNVDRMKTEAGE
VPLLAVGGGAFLAPEKLTGCSQIVRVPHGDCANAVGAAIAQVSGETDQVFRDLSRDAAIEAALTIARDRAVAAGADRDSL
KTVEVEDMPIAYLPGNALRVRARVAGGIATPDVRDAA

Sequences:

>Translated_517_residues
MRRIGIDVGGTNTDAVLIDGTTVIHSVKRATTADVTTGILDALAALRQHPATRGKVDAVVIGTTHFINAVVQRRHLQKVA
AIRLGMPASAALPPFCDWPSDLGTLVNGEVFMLEGGHDYDGRPFMPLDTAGVRTAARRIRDQGIRSVAISAIFSPLDPSG
EEQARDILLEECPDIAVTLSHDLGRIGLLERENAALLNAALRDLAATTVSAFRKAIADSGIDAPLYLTQNDGTVMQAEVA
TQFPVMSFASGATNSMRGAAHLSGLEDAMVVDVGGTTSDIGQLRHGFPREANSVVEVGGVRTLFRMPDLLSIGLGGGSHV
DPDTGRIGPLSVGYRLTQDALVFGGTQLTATDIAVAAGLLDIGDRARVQHLSAGLITAALENARQQLEDNVDRMKTEAGE
VPLLAVGGGAFLAPEKLTGCSQIVRVPHGDCANAVGAAIAQVSGETDQVFRDLSRDAAIEAALTIARDRAVAAGADRDSL
KTVEVEDMPIAYLPGNALRVRARVAGGIATPDVRDAA
>Mature_517_residues
MRRIGIDVGGTNTDAVLIDGTTVIHSVKRATTADVTTGILDALAALRQHPATRGKVDAVVIGTTHFINAVVQRRHLQKVA
AIRLGMPASAALPPFCDWPSDLGTLVNGEVFMLEGGHDYDGRPFMPLDTAGVRTAARRIRDQGIRSVAISAIFSPLDPSG
EEQARDILLEECPDIAVTLSHDLGRIGLLERENAALLNAALRDLAATTVSAFRKAIADSGIDAPLYLTQNDGTVMQAEVA
TQFPVMSFASGATNSMRGAAHLSGLEDAMVVDVGGTTSDIGQLRHGFPREANSVVEVGGVRTLFRMPDLLSIGLGGGSHV
DPDTGRIGPLSVGYRLTQDALVFGGTQLTATDIAVAAGLLDIGDRARVQHLSAGLITAALENARQQLEDNVDRMKTEAGE
VPLLAVGGGAFLAPEKLTGCSQIVRVPHGDCANAVGAAIAQVSGETDQVFRDLSRDAAIEAALTIARDRAVAAGADRDSL
KTVEVEDMPIAYLPGNALRVRARVAGGIATPDVRDAA

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 54022; Mature: 54022

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIGIDVGGTNTDAVLIDGTTVIHSVKRATTADVTTGILDALAALRQHPATRGKVDAVV
CCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
IGTTHFINAVVQRRHLQKVAAIRLGMPASAALPPFCDWPSDLGTLVNGEVFMLEGGHDYD
ECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCC
GRPFMPLDTAGVRTAARRIRDQGIRSVAISAIFSPLDPSGEEQARDILLEECPDIAVTLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEC
HDLGRIGLLERENAALLNAALRDLAATTVSAFRKAIADSGIDAPLYLTQNDGTVMQAEVA
CCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEHHH
TQFPVMSFASGATNSMRGAAHLSGLEDAMVVDVGGTTSDIGQLRHGFPREANSVVEVGGV
HHCCHHHHCCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEHHCCH
RTLFRMPDLLSIGLGGGSHVDPDTGRIGPLSVGYRLTQDALVFGGTQLTATDIAVAAGLL
HHHHHCCCCEEEECCCCCCCCCCCCCCCCEECCCEECCCCEEECCCEEEHHHHHHHHHHH
DIGDRARVQHLSAGLITAALENARQQLEDNVDRMKTEAGEVPLLAVGGGAFLAPEKLTGC
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCHHHCCH
SQIVRVPHGDCANAVGAAIAQVSGETDQVFRDLSRDAAIEAALTIARDRAVAAGADRDSL
HHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KTVEVEDMPIAYLPGNALRVRARVAGGIATPDVRDAA
EEEEECCCCEEEECCCCEEEEEEHHCCCCCCCCCCCC
>Mature Secondary Structure
MRRIGIDVGGTNTDAVLIDGTTVIHSVKRATTADVTTGILDALAALRQHPATRGKVDAVV
CCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
IGTTHFINAVVQRRHLQKVAAIRLGMPASAALPPFCDWPSDLGTLVNGEVFMLEGGHDYD
ECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCC
GRPFMPLDTAGVRTAARRIRDQGIRSVAISAIFSPLDPSGEEQARDILLEECPDIAVTLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEC
HDLGRIGLLERENAALLNAALRDLAATTVSAFRKAIADSGIDAPLYLTQNDGTVMQAEVA
CCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEHHH
TQFPVMSFASGATNSMRGAAHLSGLEDAMVVDVGGTTSDIGQLRHGFPREANSVVEVGGV
HHCCHHHHCCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEHHCCH
RTLFRMPDLLSIGLGGGSHVDPDTGRIGPLSVGYRLTQDALVFGGTQLTATDIAVAAGLL
HHHHHCCCCEEEECCCCCCCCCCCCCCCCEECCCEECCCCEEECCCEEEHHHHHHHHHHH
DIGDRARVQHLSAGLITAALENARQQLEDNVDRMKTEAGEVPLLAVGGGAFLAPEKLTGC
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCHHHCCH
SQIVRVPHGDCANAVGAAIAQVSGETDQVFRDLSRDAAIEAALTIARDRAVAAGADRDSL
HHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KTVEVEDMPIAYLPGNALRVRARVAGGIATPDVRDAA
EEEEECCCCEEEECCCCEEEEEEHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]