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The map label for this gene is 158424356

Identifier: 158424356

GI number: 158424356

Start: 3102079

End: 3103020

Strand: Direct

Name: 158424356

Synonym: AZC_2732

Alternate gene names: NA

Gene position: 3102079-3103020 (Clockwise)

Preceding gene: 158424352

Following gene: 158424357

Centisome position: 57.77

GC content: 67.3

Gene sequence:

>942_bases
ATGACCCGCGTTCTCCGCCTCGCCGCCGCCCAGATGGGCCCCACCTCCCGGACGGAGCCGCGTGCGGTGACACTCGACCG
CATGATCCGCCTTCTGGAGGCCGCCGCCGCCGATGGCGCGCAGCTCGTGGTGTTCCCGGAACTGGCCTTCACCACCTTCT
TCCCGCGCTGGCTGCTGGATGACGCCGAACTGCTGGCGAGCTTTGAAACCGCCATGCCAAATCCCGGCGTGCAGCCCCTG
TTCGACCGGGCGCGGGCGCTCGGCGTCGGTTTCTATGTGGGCTATGCGGAGCTGACGCCCGCTGGTCAGCGCTTCAACAG
CTCCATCACGGTCGGGCCGGACGGCGCCATCCTCGGCAAATATCGCAAGGTTCATCTGCCGGGCTCGGTGGAGCCGCGCC
CCGGCGACCGGTTCCAGCAGCTTGAAAAGCGCTATTTCGAATATGGCGACCTCGGCTTTCCGGCCTTCCGGGGGCCGCAG
GCGTGGCAGTCGCCTATCCTCGGCATGCTGGTGTGCAACGATCGCCGCTGGCCGGAAGCCTGGCGCGCCTATGGCCTTCA
GGGCGTCGAACTGATGCTCATGGGCTATAATTCCGCCGCCTATGACCCCAACGGCGGCAACACGGAGGATGCCGCGCTGC
GCACCTTCCACTCCACGCTGGTGGCGCAGGCCAATGCCTATATGAACGCCACCTGGGCGGTCAGCGTCGCCAAAGCGGGC
GACGAGGACGGTTCGGCCCTCATCGGCGGCTCCTGCATCGTCGATCCCAATGGCGTGCTGGTGGCGCAGGCGAAGACGCT
GGAAGACGAGGTTCTGGTCGCCGACTGCGACCTCGATGCCTGCCGGCAGGGCAAGGAGAAGATGTTCAATTTCGCCGCCC
ACCGCCGCCCCGAGCATTACCGGCGGCTGGTGGATCAGGTCGGCGCCGTTCTCCCCGCGTGA

Upstream 100 bases:

>100_bases
AAGGCTGCGTTTTTATAATCAACAACGTTGAAATGCGCAAAGAGTGTGCGAGGCTCTGACGTGACGAAAATTCGATCACT
TCTCGAAAGCCAGCCTGCCC

Downstream 100 bases:

>100_bases
TCATGCAAGCCAAGGAGTGACCGGAGTGCAGCGATGACCGGGCCTTTGCCCGACATCTCGGGCTACAGCATCGCCCCGCA
GCGCCACTGGGGGCGATGGA

Product: N-carbamyl-D-amino acid amidohydrolase

Products: NA

Alternate protein names: D-N-alpha-carbamilase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTRVLRLAAAQMGPTSRTEPRAVTLDRMIRLLEAAAADGAQLVVFPELAFTTFFPRWLLDDAELLASFETAMPNPGVQPL
FDRARALGVGFYVGYAELTPAGQRFNSSITVGPDGAILGKYRKVHLPGSVEPRPGDRFQQLEKRYFEYGDLGFPAFRGPQ
AWQSPILGMLVCNDRRWPEAWRAYGLQGVELMLMGYNSAAYDPNGGNTEDAALRTFHSTLVAQANAYMNATWAVSVAKAG
DEDGSALIGGSCIVDPNGVLVAQAKTLEDEVLVADCDLDACRQGKEKMFNFAAHRRPEHYRRLVDQVGAVLPA

Sequences:

>Translated_313_residues
MTRVLRLAAAQMGPTSRTEPRAVTLDRMIRLLEAAAADGAQLVVFPELAFTTFFPRWLLDDAELLASFETAMPNPGVQPL
FDRARALGVGFYVGYAELTPAGQRFNSSITVGPDGAILGKYRKVHLPGSVEPRPGDRFQQLEKRYFEYGDLGFPAFRGPQ
AWQSPILGMLVCNDRRWPEAWRAYGLQGVELMLMGYNSAAYDPNGGNTEDAALRTFHSTLVAQANAYMNATWAVSVAKAG
DEDGSALIGGSCIVDPNGVLVAQAKTLEDEVLVADCDLDACRQGKEKMFNFAAHRRPEHYRRLVDQVGAVLPA
>Mature_312_residues
TRVLRLAAAQMGPTSRTEPRAVTLDRMIRLLEAAAADGAQLVVFPELAFTTFFPRWLLDDAELLASFETAMPNPGVQPLF
DRARALGVGFYVGYAELTPAGQRFNSSITVGPDGAILGKYRKVHLPGSVEPRPGDRFQQLEKRYFEYGDLGFPAFRGPQA
WQSPILGMLVCNDRRWPEAWRAYGLQGVELMLMGYNSAAYDPNGGNTEDAALRTFHSTLVAQANAYMNATWAVSVAKAGD
EDGSALIGGSCIVDPNGVLVAQAKTLEDEVLVADCDLDACRQGKEKMFNFAAHRRPEHYRRLVDQVGAVLPA

Specific function: The enzyme catalyzes the hydrolysis of N-carbamoyl-D- amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=297, Percent_Identity=25.2525252525253, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: =3.5.1.77 [H]

Molecular weight: Translated: 34243; Mature: 34112

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVLRLAAAQMGPTSRTEPRAVTLDRMIRLLEAAAADGAQLVVFPELAFTTFFPRWLLD
CCHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHC
DAELLASFETAMPNPGVQPLFDRARALGVGFYVGYAELTPAGQRFNSSITVGPDGAILGK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECHHHCCCCCHHCCCEEEECCCCCEECC
YRKVHLPGSVEPRPGDRFQQLEKRYFEYGDLGFPAFRGPQAWQSPILGMLVCNDRRWPEA
EEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHH
WRAYGLQGVELMLMGYNSAAYDPNGGNTEDAALRTFHSTLVAQANAYMNATWAVSVAKAG
HHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCC
DEDGSALIGGSCIVDPNGVLVAQAKTLEDEVLVADCDLDACRQGKEKMFNFAAHRRPEHY
CCCCCEEECCEEEECCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHH
RRLVDQVGAVLPA
HHHHHHHHHHCCC
>Mature Secondary Structure 
TRVLRLAAAQMGPTSRTEPRAVTLDRMIRLLEAAAADGAQLVVFPELAFTTFFPRWLLD
CHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHC
DAELLASFETAMPNPGVQPLFDRARALGVGFYVGYAELTPAGQRFNSSITVGPDGAILGK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECHHHCCCCCHHCCCEEEECCCCCEECC
YRKVHLPGSVEPRPGDRFQQLEKRYFEYGDLGFPAFRGPQAWQSPILGMLVCNDRRWPEA
EEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHH
WRAYGLQGVELMLMGYNSAAYDPNGGNTEDAALRTFHSTLVAQANAYMNATWAVSVAKAG
HHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCC
DEDGSALIGGSCIVDPNGVLVAQAKTLEDEVLVADCDLDACRQGKEKMFNFAAHRRPEHY
CCCCCEEECCEEEECCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHH
RRLVDQVGAVLPA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9648217; 10903946 [H]