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The map label for this gene is iclR [H]

Identifier: 158424345

GI number: 158424345

Start: 3090931

End: 3091707

Strand: Direct

Name: iclR [H]

Synonym: AZC_2721

Alternate gene names: 158424345

Gene position: 3090931-3091707 (Clockwise)

Preceding gene: 158424344

Following gene: 158424346

Centisome position: 57.56

GC content: 68.08

Gene sequence:

>777_bases
ATGGGCGCCCTCGACACTGCAGTCGTCATTCTCCGTTGCTTCTCCGAAGCGCGCCCCGAGCTGAGCTTCGCGGAGATCAT
GACGGCCACCGGAATGCCCAAGAGTTCGACCTCGCGCATGCTCAGCGCACTGCGCGAGGCGCGCCTGCTGGAGCAGGACG
AGGTCACGCGGCGCTTCCGTCCCGGCCTCCTGGCCTTCGAGCTGGGCCGCCTCTATCGCGCCCATGACGATCTGATCAGC
CGCACCGAAACCGCCCTCAAGGACGTGTGTGCCCGCACAGGCCATACCGGCTATATCGCGGTGCTGGATGGCTGCGATCA
GCTGGTGCTGCGCATGGTGCCCGGCTCCAATCCGCTGCGTGTGGTGAGCCCTGCCGGCCAGCGCGGCTCGGCGCTCGCCA
CATCCAATGGCCGCGCCATGCTGGCCCGCCTGTCGGACGCGGAAATCCTCGCCCGCTTGCCGAAACCCTTTCCCAAGCTG
CCGCGCAACTGCCCGCAGTCGCCCGATGAACTGTTCCAGCGCATCGCCGAGATCCGCCGTACGGGCCGGTCCATGTCCGA
CAACGAGGCCATCGAGGGCGTCGCGTCCCAGGGCTTTGCCCTATGCAGCCGGGAGACCAGCGAAATGATCGGCATCGCCA
TCTCCTACGCCAGCCAGGCCACCCCGCCTGACGAGCGCGCCCATGTGGCGCGGGAGATGGAGGCCATGGCCCGCAGTGTC
GGACGGGCGATCGGCGATGCGGTGTGGGGCCTTGAGACGGGAGAACAGGCGCGATGA

Upstream 100 bases:

>100_bases
TGATATGAGCGGCAACTGAGCAATAGCGATTGACAGGGGAAGTCCATAGCTCGCAAAATTGGAACATGGTTCCGTATTTT
GGAACCAGCGAGACATGGAC

Downstream 100 bases:

>100_bases
ACCGCACGGGCGCCAATGTGATGGGCCTTGCGCTGCTGCCGAGCGCGCTGTTCTTCGCCCTCTTCTTTTTCCTGCCCATC
GGCCTCATGGCGGTGATGAG

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MGALDTAVVILRCFSEARPELSFAEIMTATGMPKSSTSRMLSALREARLLEQDEVTRRFRPGLLAFELGRLYRAHDDLIS
RTETALKDVCARTGHTGYIAVLDGCDQLVLRMVPGSNPLRVVSPAGQRGSALATSNGRAMLARLSDAEILARLPKPFPKL
PRNCPQSPDELFQRIAEIRRTGRSMSDNEAIEGVASQGFALCSRETSEMIGIAISYASQATPPDERAHVAREMEAMARSV
GRAIGDAVWGLETGEQAR

Sequences:

>Translated_258_residues
MGALDTAVVILRCFSEARPELSFAEIMTATGMPKSSTSRMLSALREARLLEQDEVTRRFRPGLLAFELGRLYRAHDDLIS
RTETALKDVCARTGHTGYIAVLDGCDQLVLRMVPGSNPLRVVSPAGQRGSALATSNGRAMLARLSDAEILARLPKPFPKL
PRNCPQSPDELFQRIAEIRRTGRSMSDNEAIEGVASQGFALCSRETSEMIGIAISYASQATPPDERAHVAREMEAMARSV
GRAIGDAVWGLETGEQAR
>Mature_257_residues
GALDTAVVILRCFSEARPELSFAEIMTATGMPKSSTSRMLSALREARLLEQDEVTRRFRPGLLAFELGRLYRAHDDLISR
TETALKDVCARTGHTGYIAVLDGCDQLVLRMVPGSNPLRVVSPAGQRGSALATSNGRAMLARLSDAEILARLPKPFPKLP
RNCPQSPDELFQRIAEIRRTGRSMSDNEAIEGVASQGFALCSRETSEMIGIAISYASQATPPDERAHVAREMEAMARSVG
RAIGDAVWGLETGEQAR

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=244, Percent_Identity=22.5409836065574, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082359, Length=195, Percent_Identity=24.1025641025641, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28073; Mature: 27941

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALDTAVVILRCFSEARPELSFAEIMTATGMPKSSTSRMLSALREARLLEQDEVTRRFR
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PGLLAFELGRLYRAHDDLISRTETALKDVCARTGHTGYIAVLDGCDQLVLRMVPGSNPLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCEE
VVSPAGQRGSALATSNGRAMLARLSDAEILARLPKPFPKLPRNCPQSPDELFQRIAEIRR
EECCCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHH
TGRSMSDNEAIEGVASQGFALCSRETSEMIGIAISYASQATPPDERAHVAREMEAMARSV
HCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
GRAIGDAVWGLETGEQAR
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GALDTAVVILRCFSEARPELSFAEIMTATGMPKSSTSRMLSALREARLLEQDEVTRRFR
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PGLLAFELGRLYRAHDDLISRTETALKDVCARTGHTGYIAVLDGCDQLVLRMVPGSNPLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCEE
VVSPAGQRGSALATSNGRAMLARLSDAEILARLPKPFPKLPRNCPQSPDELFQRIAEIRR
EECCCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHH
TGRSMSDNEAIEGVASQGFALCSRETSEMIGIAISYASQATPPDERAHVAREMEAMARSV
HCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
GRAIGDAVWGLETGEQAR
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]