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The map label for this gene is hbpA [H]

Identifier: 158424249

GI number: 158424249

Start: 2959303

End: 2961036

Strand: Direct

Name: hbpA [H]

Synonym: AZC_2625

Alternate gene names: 158424249

Gene position: 2959303-2961036 (Clockwise)

Preceding gene: 158424248

Following gene: 158424250

Centisome position: 55.11

GC content: 63.15

Gene sequence:

>1734_bases
ATGATGATGAGTGGCCGCATAAGGCCGCCGCCGATCGGGGAACGCACGACGAGCCACCGGACAAGAGCAGGGAAGATTCC
GTCAATGAACAGACGTTCGTTTATGCAGCTGCTTTCGGGCGCGTCTCTGACCGCCGTGTCCCTCATGGATACGGAACTCG
GCCAGATGGTGGGCCTGGGCGCGGGTCCGGCGCAGGCCCAGAGCAAGCCCGGCGTGCTGCGGGTCGCCATGACCGCCGCA
GACATCCCGCTCACCACCGGCCAGCCCAGCCAAGGCGCGGAAGGCATCCGCTTCATGGGCATCACGCTCTATGACGGCCT
GACGCGCTGGGACCTCTCGAAGGCCGACCAGGCCGCGCAGGTCATCCCTGATCTTGCCGAAAGCTGGACCGTGAACCCGC
AGGATCAGAAGGTCTGGACCTTCAAGCTGCGCAAGGGCGTCAAGTTCCACGACGGGTCCGACTTCAACGCCGATGCGGTG
GTGTGGAACTTCGACAAACTGATGAAGCCCGACGCGCCGCAGTTCGATCAGGCCCAGTCCAATCAGGCCGCGTCCTACGA
TGCGAACATCGCCTCCTGGCGCAAGATCGACGATTATACGGTTGAGATCGCCACCAAGCGCGTGGACGCCGTGCTGATCT
ACAATCTCGCCGGTCTTTTCATGTCGAGCCCAAAGCGCTGGGAAGAGGTGGGCAAAGACTGGGCGAAGTTCGCCGAGAAG
CCGTCCGGCACCGGGCCATGGATCCTGGAGAGCTTCAAGCCGCGCGAACGCGCCGAACTGGTGCGCAACACCGAACACTG
GGACAAGACCCGCATCCCAAAGTCCGAACGGCTGATCCTGCTGCCCATGCCCGACGCCAACACCCGCGTCGCGGCCCTCC
TCTCCGGGCAGGTCGACTGGATCGAGGCGCCGCCGCCGGATGCGGTGCCGCGCCTGAAGTCCCAGAAGATGCAGATCGTC
ACCAATCTCTATCCGCACATCTGGCCCTACCAGCTCTCTTACCTTGAGGATTCGCCGTTCAAGGACATTCGGATCCGCAA
GGCGGCCAACCTCGCCATTGATCGCGACGGGATCGTGAAGATGCTCGGCGGCCTCGCCGCGCCTGCCAAGGGCATGGTCG
ACGAAAAGCACCCCTGGTTCGGCAAGCCCACCTTCGAGATCAAATATGATCCGGAAGGCGCCAAGAAACTGCTGAAGGAC
GCGGGCTACGGGCCGGACAAGCCGGTGAAGGCCAAGTTCATCATCTCACCCTCCGGCTCCGGCCAGATGCAGCCGCTGCC
CATGAACGAGTTCATCAAGGAGAACTTCAAGGACGTCGGCATCGACCTCGAATTCGAGGTGCTGGACTGGGAAGCTCTGC
GCGCCCGTCGCCGGCTTGGCGCCTGGGCCCCGGAGAACAAGGGCCGACACGGCATCAACAACAGCTGGGCCTACTGGGAT
CCGGATATCGGCCTCATCGGCACCGCCGCATCCTTTGCCAAGGTGCCAGGAGGCTTCAACTGGGGCGATTTCAACGACGC
GAAGACGGACGAACTGTCCACCAAGGCCAAGGCCGCCTTCGATCCGGTCGAGCAGAACAAGATCCTCGCCGAGTTGCACA
GCCACCTCGTGGATCAGGCCATGTGGATCTGGGTGGTGCATGACCTCAATCCCCGTGCCCTGCGTCCCAATGTGAAGGGC
TTCGTGCAGGCGCAGAGCTGGTTCCAGGACCTGACCCCCGTCTCGGTGACCTGA

Upstream 100 bases:

>100_bases
ACGCGCTTGTCCTGCGCCTCGGGGCTGCGTTCGAGCGGGAAACCGATTTCCGCCGCCACCGGCCGTCGCTGCACCAGCCG
GAGGAGGCCATGGCCGCGCA

Downstream 100 bases:

>100_bases
TGCGGTGAACCCGGCCGGCCTGCCGGCCGGGTCGCCACGATGCGTCCCGGCATCTGTGTCGCGGAAGGGCGAGCAGAGGC
CACCCGAACCGAGCTCGAAG

Product: ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MMMSGRIRPPPIGERTTSHRTRAGKIPSMNRRSFMQLLSGASLTAVSLMDTELGQMVGLGAGPAQAQSKPGVLRVAMTAA
DIPLTTGQPSQGAEGIRFMGITLYDGLTRWDLSKADQAAQVIPDLAESWTVNPQDQKVWTFKLRKGVKFHDGSDFNADAV
VWNFDKLMKPDAPQFDQAQSNQAASYDANIASWRKIDDYTVEIATKRVDAVLIYNLAGLFMSSPKRWEEVGKDWAKFAEK
PSGTGPWILESFKPRERAELVRNTEHWDKTRIPKSERLILLPMPDANTRVAALLSGQVDWIEAPPPDAVPRLKSQKMQIV
TNLYPHIWPYQLSYLEDSPFKDIRIRKAANLAIDRDGIVKMLGGLAAPAKGMVDEKHPWFGKPTFEIKYDPEGAKKLLKD
AGYGPDKPVKAKFIISPSGSGQMQPLPMNEFIKENFKDVGIDLEFEVLDWEALRARRRLGAWAPENKGRHGINNSWAYWD
PDIGLIGTAASFAKVPGGFNWGDFNDAKTDELSTKAKAAFDPVEQNKILAELHSHLVDQAMWIWVVHDLNPRALRPNVKG
FVQAQSWFQDLTPVSVT

Sequences:

>Translated_577_residues
MMMSGRIRPPPIGERTTSHRTRAGKIPSMNRRSFMQLLSGASLTAVSLMDTELGQMVGLGAGPAQAQSKPGVLRVAMTAA
DIPLTTGQPSQGAEGIRFMGITLYDGLTRWDLSKADQAAQVIPDLAESWTVNPQDQKVWTFKLRKGVKFHDGSDFNADAV
VWNFDKLMKPDAPQFDQAQSNQAASYDANIASWRKIDDYTVEIATKRVDAVLIYNLAGLFMSSPKRWEEVGKDWAKFAEK
PSGTGPWILESFKPRERAELVRNTEHWDKTRIPKSERLILLPMPDANTRVAALLSGQVDWIEAPPPDAVPRLKSQKMQIV
TNLYPHIWPYQLSYLEDSPFKDIRIRKAANLAIDRDGIVKMLGGLAAPAKGMVDEKHPWFGKPTFEIKYDPEGAKKLLKD
AGYGPDKPVKAKFIISPSGSGQMQPLPMNEFIKENFKDVGIDLEFEVLDWEALRARRRLGAWAPENKGRHGINNSWAYWD
PDIGLIGTAASFAKVPGGFNWGDFNDAKTDELSTKAKAAFDPVEQNKILAELHSHLVDQAMWIWVVHDLNPRALRPNVKG
FVQAQSWFQDLTPVSVT
>Mature_577_residues
MMMSGRIRPPPIGERTTSHRTRAGKIPSMNRRSFMQLLSGASLTAVSLMDTELGQMVGLGAGPAQAQSKPGVLRVAMTAA
DIPLTTGQPSQGAEGIRFMGITLYDGLTRWDLSKADQAAQVIPDLAESWTVNPQDQKVWTFKLRKGVKFHDGSDFNADAV
VWNFDKLMKPDAPQFDQAQSNQAASYDANIASWRKIDDYTVEIATKRVDAVLIYNLAGLFMSSPKRWEEVGKDWAKFAEK
PSGTGPWILESFKPRERAELVRNTEHWDKTRIPKSERLILLPMPDANTRVAALLSGQVDWIEAPPPDAVPRLKSQKMQIV
TNLYPHIWPYQLSYLEDSPFKDIRIRKAANLAIDRDGIVKMLGGLAAPAKGMVDEKHPWFGKPTFEIKYDPEGAKKLLKD
AGYGPDKPVKAKFIISPSGSGQMQPLPMNEFIKENFKDVGIDLEFEVLDWEALRARRRLGAWAPENKGRHGINNSWAYWD
PDIGLIGTAASFAKVPGGFNWGDFNDAKTDELSTKAKAAFDPVEQNKILAELHSHLVDQAMWIWVVHDLNPRALRPNVKG
FVQAQSWFQDLTPVSVT

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=490, Percent_Identity=26.3265306122449, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1787052, Length=525, Percent_Identity=27.6190476190476, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081878, Length=491, Percent_Identity=23.4215885947047, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787495, Length=498, Percent_Identity=23.2931726907631, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789887, Length=473, Percent_Identity=24.7357293868922, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787762, Length=473, Percent_Identity=24.5243128964059, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789397, Length=480, Percent_Identity=22.9166666666667, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787551, Length=339, Percent_Identity=24.188790560472, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64426; Mature: 64426

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMSGRIRPPPIGERTTSHRTRAGKIPSMNRRSFMQLLSGASLTAVSLMDTELGQMVGLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCC
AGPAQAQSKPGVLRVAMTAADIPLTTGQPSQGAEGIRFMGITLYDGLTRWDLSKADQAAQ
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCHHCCCHHHHHHHH
VIPDLAESWTVNPQDQKVWTFKLRKGVKFHDGSDFNADAVVWNFDKLMKPDAPQFDQAQS
HHHHHHHHCCCCCCCCEEEEEEECCCCEECCCCCCCCCEEEEEHHHHCCCCCCCCCHHCC
NQAASYDANIASWRKIDDYTVEIATKRVDAVLIYNLAGLFMSSPKRWEEVGKDWAKFAEK
CCCCCCCCCHHHCCCCCCEEEEEEHHHHCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
PSGTGPWILESFKPRERAELVRNTEHWDKTRIPKSERLILLPMPDANTRVAALLSGQVDW
CCCCCCHHHCCCCCHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCEE
IEAPPPDAVPRLKSQKMQIVTNLYPHIWPYQLSYLEDSPFKDIRIRKAANLAIDRDGIVK
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEHHCCCEECCCHHHH
MLGGLAAPAKGMVDEKHPWFGKPTFEIKYDPEGAKKLLKDAGYGPDKPVKAKFIISPSGS
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCEEEEEECCCCC
GQMQPLPMNEFIKENFKDVGIDLEFEVLDWEALRARRRLGAWAPENKGRHGINNSWAYWD
CCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
PDIGLIGTAASFAKVPGGFNWGDFNDAKTDELSTKAKAAFDPVEQNKILAELHSHLVDQA
CCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHE
MWIWVVHDLNPRALRPNVKGFVQAQSWFQDLTPVSVT
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMMSGRIRPPPIGERTTSHRTRAGKIPSMNRRSFMQLLSGASLTAVSLMDTELGQMVGLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCC
AGPAQAQSKPGVLRVAMTAADIPLTTGQPSQGAEGIRFMGITLYDGLTRWDLSKADQAAQ
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCHHCCCHHHHHHHH
VIPDLAESWTVNPQDQKVWTFKLRKGVKFHDGSDFNADAVVWNFDKLMKPDAPQFDQAQS
HHHHHHHHCCCCCCCCEEEEEEECCCCEECCCCCCCCCEEEEEHHHHCCCCCCCCCHHCC
NQAASYDANIASWRKIDDYTVEIATKRVDAVLIYNLAGLFMSSPKRWEEVGKDWAKFAEK
CCCCCCCCCHHHCCCCCCEEEEEEHHHHCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
PSGTGPWILESFKPRERAELVRNTEHWDKTRIPKSERLILLPMPDANTRVAALLSGQVDW
CCCCCCHHHCCCCCHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCEE
IEAPPPDAVPRLKSQKMQIVTNLYPHIWPYQLSYLEDSPFKDIRIRKAANLAIDRDGIVK
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEHHCCCEECCCHHHH
MLGGLAAPAKGMVDEKHPWFGKPTFEIKYDPEGAKKLLKDAGYGPDKPVKAKFIISPSGS
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCEEEEEECCCCC
GQMQPLPMNEFIKENFKDVGIDLEFEVLDWEALRARRRLGAWAPENKGRHGINNSWAYWD
CCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
PDIGLIGTAASFAKVPGGFNWGDFNDAKTDELSTKAKAAFDPVEQNKILAELHSHLVDQA
CCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHE
MWIWVVHDLNPRALRPNVKGFVQAQSWFQDLTPVSVT
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]