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The map label for this gene is hbpA [H]

Identifier: 158424250

GI number: 158424250

Start: 2961150

End: 2962799

Strand: Direct

Name: hbpA [H]

Synonym: AZC_2626

Alternate gene names: 158424250

Gene position: 2961150-2962799 (Clockwise)

Preceding gene: 158424249

Following gene: 158424251

Centisome position: 55.14

GC content: 63.94

Gene sequence:

>1650_bases
ATGAATAGACGCAGGTTCATGAAGCTGCTGTCGGGCGTGTCGCTCACCGCCATGACAGTTACCGCCGTGGAGCTCGCCGA
GATGGCCGGTCCGCTGGTGGCACCGGCCTATGCCCAGAGCAAGCCAGGCGTGCTGCGTGTGGCGATGACCGCCGGTGACA
TTCCGCTTACCACTGGCCAGCCCAGCCAGGGTGGCGAAGGCGTCCGCTTCATGGGCATCACCGTCTATGATGGCCTGACC
CGCTGGGATCTCTCGCACGCCGACCGGGCGCCGGTGATCGTGCCCGACCTTGCCGAGAGCTGGAGCGTCAGCGAAAGCGA
CCGGAAGGTCTGGACATTCAAGCTGCGCAAGGATGTGAAATTCCACGACGGCTCGGAGTTCACGGCCGATGCCGTGGTCT
TCAATTTCGACAAGCTGCTGAGGAAGGACGCGCCCCAGTACGATCCCGCTCAGTCGGCACAGGGCTCGCTCTGGACCGGG
CCGCTGGCGAGCTGGCGCAAGATCGACGACTACACGGTGGAGATCACCACCAAGCAGGTGGATGCGATCCTGCCCTACAT
GCTCGCCAACCTGTTCATGTCGAGCCCCAAGCGCTGGGAGGAGGTGGGCAAGGACTGGGCGAAGTTCGCCGAGAAGCCGT
CCGGCACGGGGCCGTGGAAGCTTGTCGCCTTCAAGCCGCGCGAGCGTGCCGAACTGGTGCGCAACACCGAGCACTGGGAC
AAGAGCCGCATCCCGAAATCCGAGCAGTTGATCCTGTTCCCGATGCCCGACGCCAACACCCGCGCCGCGGCCCTGCTCTC
CGGGCAGGTGGACTTCGTGGAAGCGCCGCCGCCGGACGTGATCCCGCGCCTCAAGGCGGCGAAGATGCAGATCGTCACCA
ACATCTATCCGCATGTTTGGCCCTACCAGATCAGCGTGCTGGAGGATTCCCCCTTCAAGGACATTCGGATCCGCAAGGCG
GCCAACCTCGCCATTGATCGCGAGGGGCTGGTAAAGCTGCTGGGCGGCCTCGCCCTGCCGGCAAAGGGGCATGTGGACCC
CGCTCATCCCTGGTTCGGCAAGCCCACCTTCGAGATCAAATACGACCCGGAACAGGCCATGGCCCTGCTCAAGGAGGCCG
GCTACGGCCCGGACAAGCCGGTGCAGCTGAAGGTGATCATCTCGCCCTCCGGCTCCGGCCAGATGCAGCCGCTGGCCATG
AACGAATTCATCAAGGAGAATTTCAAGGACGTCGGCATCGAAGTGGAATTCGAGGTGTTGGACTGGGAAGCTCTGCGGAC
CCGACGCCGCCTGGGCGCCTGGGCGCCGGAGAACAAGGGCCGGCACGGCATCAACAATTCCTTTGCCTATTGGGATCCGG
ACATCGGTCTCGTCAGCACCGCGTCCTCGGACGCCAAGGTGCCGTTCGGCTTCAACTGGGGCGGCTACAGCAATCCCAAG
GCCGATGCCCTCGCCAAGCGGGCCAAGGAGACCTTCGATCTTGAGGCGCAGAACCGCATTCTCGCCGAACTGCATGGTGT
CATCGTCGACGACGCCATGTGGATCTGGATGGTGCACGACCTCAATCCCCGCGCCCTGCGGCCCAATGTGAAGGGGTTCG
TGCAGGCGCAAAGCTGGTTCCAGGATCTCACCCCCGTCATCGTCGAGTAG

Upstream 100 bases:

>100_bases
GCCGGCCTGCCGGCCGGGTCGCCACGATGCGTCCCGGCATCTGTGTCGCGGAAGGGCGAGCAGAGGCCACCCGAACCGAG
CTCGAAGATGAGATCTTTCG

Downstream 100 bases:

>100_bases
CGCGCCCCCTTGCAACGGCGGCGCCCCGCCCGGGTCGCCGCCGCAGACCGGAAAGCCGATCCCATGCTCGTCTATGTGCT
GCGCCGCATTCTCTACACGG

Product: ABC transporter substrate-binding protein

Products: NA

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MNRRRFMKLLSGVSLTAMTVTAVELAEMAGPLVAPAYAQSKPGVLRVAMTAGDIPLTTGQPSQGGEGVRFMGITVYDGLT
RWDLSHADRAPVIVPDLAESWSVSESDRKVWTFKLRKDVKFHDGSEFTADAVVFNFDKLLRKDAPQYDPAQSAQGSLWTG
PLASWRKIDDYTVEITTKQVDAILPYMLANLFMSSPKRWEEVGKDWAKFAEKPSGTGPWKLVAFKPRERAELVRNTEHWD
KSRIPKSEQLILFPMPDANTRAAALLSGQVDFVEAPPPDVIPRLKAAKMQIVTNIYPHVWPYQISVLEDSPFKDIRIRKA
ANLAIDREGLVKLLGGLALPAKGHVDPAHPWFGKPTFEIKYDPEQAMALLKEAGYGPDKPVQLKVIISPSGSGQMQPLAM
NEFIKENFKDVGIEVEFEVLDWEALRTRRRLGAWAPENKGRHGINNSFAYWDPDIGLVSTASSDAKVPFGFNWGGYSNPK
ADALAKRAKETFDLEAQNRILAELHGVIVDDAMWIWMVHDLNPRALRPNVKGFVQAQSWFQDLTPVIVE

Sequences:

>Translated_549_residues
MNRRRFMKLLSGVSLTAMTVTAVELAEMAGPLVAPAYAQSKPGVLRVAMTAGDIPLTTGQPSQGGEGVRFMGITVYDGLT
RWDLSHADRAPVIVPDLAESWSVSESDRKVWTFKLRKDVKFHDGSEFTADAVVFNFDKLLRKDAPQYDPAQSAQGSLWTG
PLASWRKIDDYTVEITTKQVDAILPYMLANLFMSSPKRWEEVGKDWAKFAEKPSGTGPWKLVAFKPRERAELVRNTEHWD
KSRIPKSEQLILFPMPDANTRAAALLSGQVDFVEAPPPDVIPRLKAAKMQIVTNIYPHVWPYQISVLEDSPFKDIRIRKA
ANLAIDREGLVKLLGGLALPAKGHVDPAHPWFGKPTFEIKYDPEQAMALLKEAGYGPDKPVQLKVIISPSGSGQMQPLAM
NEFIKENFKDVGIEVEFEVLDWEALRTRRRLGAWAPENKGRHGINNSFAYWDPDIGLVSTASSDAKVPFGFNWGGYSNPK
ADALAKRAKETFDLEAQNRILAELHGVIVDDAMWIWMVHDLNPRALRPNVKGFVQAQSWFQDLTPVIVE
>Mature_549_residues
MNRRRFMKLLSGVSLTAMTVTAVELAEMAGPLVAPAYAQSKPGVLRVAMTAGDIPLTTGQPSQGGEGVRFMGITVYDGLT
RWDLSHADRAPVIVPDLAESWSVSESDRKVWTFKLRKDVKFHDGSEFTADAVVFNFDKLLRKDAPQYDPAQSAQGSLWTG
PLASWRKIDDYTVEITTKQVDAILPYMLANLFMSSPKRWEEVGKDWAKFAEKPSGTGPWKLVAFKPRERAELVRNTEHWD
KSRIPKSEQLILFPMPDANTRAAALLSGQVDFVEAPPPDVIPRLKAAKMQIVTNIYPHVWPYQISVLEDSPFKDIRIRKA
ANLAIDREGLVKLLGGLALPAKGHVDPAHPWFGKPTFEIKYDPEQAMALLKEAGYGPDKPVQLKVIISPSGSGQMQPLAM
NEFIKENFKDVGIEVEFEVLDWEALRTRRRLGAWAPENKGRHGINNSFAYWDPDIGLVSTASSDAKVPFGFNWGGYSNPK
ADALAKRAKETFDLEAQNRILAELHGVIVDDAMWIWMVHDLNPRALRPNVKGFVQAQSWFQDLTPVIVE

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787052, Length=457, Percent_Identity=29.1028446389497, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789966, Length=466, Percent_Identity=26.8240343347639, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787495, Length=505, Percent_Identity=24.7524752475248, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081878, Length=473, Percent_Identity=24.5243128964059, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787762, Length=461, Percent_Identity=26.0303687635575, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789887, Length=383, Percent_Identity=27.154046997389, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789397, Length=460, Percent_Identity=21.9565217391304, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787551, Length=513, Percent_Identity=22.8070175438596, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61341; Mature: 61341

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRRFMKLLSGVSLTAMTVTAVELAEMAGPLVAPAYAQSKPGVLRVAMTAGDIPLTTGQ
CCHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCCHHCCCCCCEEEEEEECCCEECCCCC
PSQGGEGVRFMGITVYDGLTRWDLSHADRAPVIVPDLAESWSVSESDRKVWTFKLRKDVK
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEECCCE
FHDGSEFTADAVVFNFDKLLRKDAPQYDPAQSAQGSLWTGPLASWRKIDDYTVEITTKQV
ECCCCCCCHHHEEECHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHH
DAILPYMLANLFMSSPKRWEEVGKDWAKFAEKPSGTGPWKLVAFKPRERAELVRNTEHWD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCHHH
KSRIPKSEQLILFPMPDANTRAAALLSGQVDFVEAPPPDVIPRLKAAKMQIVTNIYPHVW
HHCCCCCCCEEEEECCCCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
PYQISVLEDSPFKDIRIRKAANLAIDREGLVKLLGGLALPAKGHVDPAHPWFGKPTFEIK
CEEEEEECCCCCCCEEEEEHHCCEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEE
YDPEQAMALLKEAGYGPDKPVQLKVIISPSGSGQMQPLAMNEFIKENFKDVGIEVEFEVL
ECHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEE
DWEALRTRRRLGAWAPENKGRHGINNSFAYWDPDIGLVSTASSDAKVPFGFNWGGYSNPK
CHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCH
ADALAKRAKETFDLEAQNRILAELHGVIVDDAMWIWMVHDLNPRALRPNVKGFVQAQSWF
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHH
QDLTPVIVE
HCCCHHHCC
>Mature Secondary Structure
MNRRRFMKLLSGVSLTAMTVTAVELAEMAGPLVAPAYAQSKPGVLRVAMTAGDIPLTTGQ
CCHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCCHHCCCCCCEEEEEEECCCEECCCCC
PSQGGEGVRFMGITVYDGLTRWDLSHADRAPVIVPDLAESWSVSESDRKVWTFKLRKDVK
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEECCCE
FHDGSEFTADAVVFNFDKLLRKDAPQYDPAQSAQGSLWTGPLASWRKIDDYTVEITTKQV
ECCCCCCCHHHEEECHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHH
DAILPYMLANLFMSSPKRWEEVGKDWAKFAEKPSGTGPWKLVAFKPRERAELVRNTEHWD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCHHH
KSRIPKSEQLILFPMPDANTRAAALLSGQVDFVEAPPPDVIPRLKAAKMQIVTNIYPHVW
HHCCCCCCCEEEEECCCCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
PYQISVLEDSPFKDIRIRKAANLAIDREGLVKLLGGLALPAKGHVDPAHPWFGKPTFEIK
CEEEEEECCCCCCCEEEEEHHCCEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEE
YDPEQAMALLKEAGYGPDKPVQLKVIISPSGSGQMQPLAMNEFIKENFKDVGIEVEFEVL
ECHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEE
DWEALRTRRRLGAWAPENKGRHGINNSFAYWDPDIGLVSTASSDAKVPFGFNWGGYSNPK
CHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCH
ADALAKRAKETFDLEAQNRILAELHGVIVDDAMWIWMVHDLNPRALRPNVKGFVQAQSWF
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHH
QDLTPVIVE
HCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]