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The map label for this gene is serB [H]

Identifier: 158424198

GI number: 158424198

Start: 2900511

End: 2901353

Strand: Reverse

Name: serB [H]

Synonym: AZC_2574

Alternate gene names: 158424198

Gene position: 2901353-2900511 (Counterclockwise)

Preceding gene: 158424200

Following gene: 158424190

Centisome position: 54.03

GC content: 67.26

Gene sequence:

>843_bases
GTGGTGGCTGCCGCCCGCGCGGTTCTGCCCGGGGCGGACGAGCCCATCACTCTTAATGCCGACGTGGCGAGCGAGATCCA
TTTCGACCCGCCCGCCGACGTCTCCGTCCACGGCCTGGAGGATGAGGTCCGCGCCGCCCTTGATGGCGCGCCGGTGGATG
TGGTGGTGCAGCTTGCGGCCGGGCGGCGCAAGCGCCTGTTCCTCGCGGACATGGATTCCACCATGATCGGGCAGGAATGC
ATCGACGAGCTGGCCGATCTTGTCGGCCTCAAGGCCCATGTCTCCGCCATCACCGAGCGGGCCATGCGGGGCGAGATCTC
CTTCGAGCCGGCGCTCCGCGAGCGCGTGGCGCTGCTGAAGGGCCTCGCCGCCGAGGTGGTGGATGATGTCCTGCGCGAGC
GCATCACGCTGATGCCGGGCGGCAAGGCGCTCGTTTCCACCATGAAGGCGAACGGGGCCTATACGGCACTGGTCTCGGGC
GGCTTCACGCTGTTCACCAGCGCGGTGGCGCAGATGATCGGCTTCGACGAGAACCGCGCGAACATTCTGGAGACGGACGG
CGGCAAACTCTCCGGCACCGTGACCGAACCGATCCTTGGCAAGGAAGCCAAGCTCGCGACCCTCGTGGAGCTGCGCGACC
GCCTGCACCTTTCGCCCTCGGAGACAATGGCCGTGGGCGATGGGGCGAATGATCTCGCCATGCTGGGGGAAGCCGGTCTT
GGCGTCGCCTATCACGCCAAGCCCAAGGTGGCGGCGGAAGCCAAGGCCCGTGTGGACCATGGCGACCTCACCGCGCTCCT
TTATATGCAAGGTTACCACCGCGACGATTTCCGCGAGGGCTGA

Upstream 100 bases:

>100_bases
GAGCACCGCCAATGGTTTCAATGCTTCAGAGTCCCGCAGTCCCATGGTCTATGTCGCGACACTTATCTCAAATCCCGCCC
ACCCCGCCATAACCCGCGAG

Downstream 100 bases:

>100_bases
CCTGGACCTTCAGGTGGCACGCAAAGCCCCCGGCAGGGCCGGGGGCTGGAGCGGGCTCAGGCGCTGCGGATGCGGGCGAC
GAAGTTCTCCGTCGCCCGGC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MVAAARAVLPGADEPITLNADVASEIHFDPPADVSVHGLEDEVRAALDGAPVDVVVQLAAGRRKRLFLADMDSTMIGQEC
IDELADLVGLKAHVSAITERAMRGEISFEPALRERVALLKGLAAEVVDDVLRERITLMPGGKALVSTMKANGAYTALVSG
GFTLFTSAVAQMIGFDENRANILETDGGKLSGTVTEPILGKEAKLATLVELRDRLHLSPSETMAVGDGANDLAMLGEAGL
GVAYHAKPKVAAEAKARVDHGDLTALLYMQGYHRDDFREG

Sequences:

>Translated_280_residues
MVAAARAVLPGADEPITLNADVASEIHFDPPADVSVHGLEDEVRAALDGAPVDVVVQLAAGRRKRLFLADMDSTMIGQEC
IDELADLVGLKAHVSAITERAMRGEISFEPALRERVALLKGLAAEVVDDVLRERITLMPGGKALVSTMKANGAYTALVSG
GFTLFTSAVAQMIGFDENRANILETDGGKLSGTVTEPILGKEAKLATLVELRDRLHLSPSETMAVGDGANDLAMLGEAGL
GVAYHAKPKVAAEAKARVDHGDLTALLYMQGYHRDDFREG
>Mature_280_residues
MVAAARAVLPGADEPITLNADVASEIHFDPPADVSVHGLEDEVRAALDGAPVDVVVQLAAGRRKRLFLADMDSTMIGQEC
IDELADLVGLKAHVSAITERAMRGEISFEPALRERVALLKGLAAEVVDDVLRERITLMPGGKALVSTMKANGAYTALVSG
GFTLFTSAVAQMIGFDENRANILETDGGKLSGTVTEPILGKEAKLATLVELRDRLHLSPSETMAVGDGANDLAMLGEAGL
GVAYHAKPKVAAEAKARVDHGDLTALLYMQGYHRDDFREG

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=167, Percent_Identity=32.9341317365269, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1790849, Length=219, Percent_Identity=44.2922374429224, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI115534454, Length=170, Percent_Identity=33.5294117647059, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=170, Percent_Identity=33.5294117647059, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534458, Length=172, Percent_Identity=33.1395348837209, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=258, Percent_Identity=34.8837209302326, Blast_Score=161, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24661601, Length=211, Percent_Identity=30.3317535545024, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 29625; Mature: 29625

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAAARAVLPGADEPITLNADVASEIHFDPPADVSVHGLEDEVRAALDGAPVDVVVQLAA
CCCCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCEEECCHHHHHHHHCCCCHHHHHHHHC
GRRKRLFLADMDSTMIGQECIDELADLVGLKAHVSAITERAMRGEISFEPALRERVALLK
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GLAAEVVDDVLRERITLMPGGKALVSTMKANGAYTALVSGGFTLFTSAVAQMIGFDENRA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCC
NILETDGGKLSGTVTEPILGKEAKLATLVELRDRLHLSPSETMAVGDGANDLAMLGEAGL
CEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHCCCCC
GVAYHAKPKVAAEAKARVDHGDLTALLYMQGYHRDDFREG
CEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MVAAARAVLPGADEPITLNADVASEIHFDPPADVSVHGLEDEVRAALDGAPVDVVVQLAA
CCCCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCEEECCHHHHHHHHCCCCHHHHHHHHC
GRRKRLFLADMDSTMIGQECIDELADLVGLKAHVSAITERAMRGEISFEPALRERVALLK
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GLAAEVVDDVLRERITLMPGGKALVSTMKANGAYTALVSGGFTLFTSAVAQMIGFDENRA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCC
NILETDGGKLSGTVTEPILGKEAKLATLVELRDRLHLSPSETMAVGDGANDLAMLGEAGL
CEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHCCCCC
GVAYHAKPKVAAEAKARVDHGDLTALLYMQGYHRDDFREG
CEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]