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The map label for this gene is degP [H]

Identifier: 158424152

GI number: 158424152

Start: 2865152

End: 2866630

Strand: Reverse

Name: degP [H]

Synonym: AZC_2528

Alternate gene names: 158424152

Gene position: 2866630-2865152 (Counterclockwise)

Preceding gene: 158424153

Following gene: 158424151

Centisome position: 53.38

GC content: 70.05

Gene sequence:

>1479_bases
ATGGGTTTTGCCGGCGTGCGGTCCTGGGTGGGAGCGGTTCTGGCGGGCGGCCTCGTCGTTGCCGGTCTTTCGGTCGCCGT
GGCGCAGCAGGTCGAACGGCAGGCCCCCGCCGGGCCGCCGGCGCATGCCCAGGCGGGAACCGTCGTTCCGTCTTCGGCGG
CGGCGATGAAGATGAGTTTCGCCCCCGTGGTGGCGCGCACCGCACCGGCGGTCGTCAATGTCTATGCGCTGAAGATCGCC
CAGCGCACCAATCCCTTCATCGATGACCCCTTCTTCCGGCGCTTCTTCGGCGGCGGCCCTGGAGGCGGCGGGCTCGGCGC
GCCCGAGCGGGTGCAGCGTTCGCTCGGCTCGGGCGTCATCGTCGATCCCAGCGGCCTCGTGGTCACCAACCAGCACGTGA
TCCAGGGCGCGGACCAGATCCGCATCGCCCTCAACGACAAGCGCGAGTTCGACGCCGAGGTGCTCCTCTCCGACCAGCGC
ACGGACCTTGCCGTGCTGCGCATCAAGGGGGAGGGGGCCAAATTCTCCTCGCTGGAGATCGGCAATTCGGACGAACTCGC
GGTCGGCGATCTCGTGCTTGCCATCGGCGATCCCTTCGGCGTCGGCCAGACGGTGACGCAGGGCATCGTCTCTGCGCTCG
CGCGCACGCAGGTGGGCGTGTCCGACTATCAGTTCTTCATCCAGACGGATGCCGCCATCAATCCCGGCAACTCCGGCGGC
GCCCTCGTGGACATGGACGGGCGCCTCGTGGGCATCAACAGCGCCATCTATTCGCGCTCGGGCGGCTCGCATGGCATCGG
CTTCGCCATCCCCGCCAATATGGTGAAGGTGGTGGTCGCCTCGGCCAAAGCCGGCGGCAAGACGGTGCGCCGGCCCTGGC
TCGGCGCCAAGCTCCAGCGCGTGACGCCGGAGATCGCCGATAGCCTCGGCCTCCAGCGGCCCACTGGCGCACTTGTCCAG
TCCGTGGCGACGGACGGACCCGCCGCGCGTGCCGGCCTGAAGACGGGCGACCTCATCGTGGCGGTCGAGGGGCAGGCGAT
CGATGATCCCGAATCCCTGAACTATCGCTGGGGCACCCGCCCGCTCGGCGGCAAGGCCAATCTCGGTATCGTCCGGCAGG
GCCGCGACCAGACCCTTGTGGTGACGCTGGAGCCCCCGCCGGAGAGCGTGCCGCGGGACGAGGTGGTGATCTCCTCGCGC
TCGCCCTTTGCCGGCGCGCGGGTCCTCAATGTCTCCCCGGCCGTCGCTGACGAACTGCGCCTCGATGTGGACGAGGGCGT
GGTCGTGATCTCGGAGGTGGCGGACGGCTCGCCCGCCGATGCGGCGGGCTTCCGGGCGGGCGACATCATCCTCGAGGTGA
ATGGCGGCCGCATCGAACGCACCAAGGATCTGGTGGCCGCCACCCGCACCCCGTCCCGCGCCTGGAAGGTGACGGTGGCT
CGCGGCGGGCGCACCATCACTGCCGTTCTCGGCGGCTGA

Upstream 100 bases:

>100_bases
AAGGGCGGCCTCACGGTCGCCCTTCTTTCGTTTAATCAGCACGAAAGCGTGCCGACTCGTCCGGGCCGGCGCGCGACGAC
TTGAGCGAGGGTGACAGACC

Downstream 100 bases:

>100_bases
GTCGCATGCCCGCCGGCTGGCGGGCGGGACACGAAACACCATCTATCAAGGGCTGCCGGTTGCCGGCGGCCCTTGTCCGC
GTGATGCGCGGACCCCGGAG

Product: peptidase S1C, Do precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MGFAGVRSWVGAVLAGGLVVAGLSVAVAQQVERQAPAGPPAHAQAGTVVPSSAAAMKMSFAPVVARTAPAVVNVYALKIA
QRTNPFIDDPFFRRFFGGGPGGGGLGAPERVQRSLGSGVIVDPSGLVVTNQHVIQGADQIRIALNDKREFDAEVLLSDQR
TDLAVLRIKGEGAKFSSLEIGNSDELAVGDLVLAIGDPFGVGQTVTQGIVSALARTQVGVSDYQFFIQTDAAINPGNSGG
ALVDMDGRLVGINSAIYSRSGGSHGIGFAIPANMVKVVVASAKAGGKTVRRPWLGAKLQRVTPEIADSLGLQRPTGALVQ
SVATDGPAARAGLKTGDLIVAVEGQAIDDPESLNYRWGTRPLGGKANLGIVRQGRDQTLVVTLEPPPESVPRDEVVISSR
SPFAGARVLNVSPAVADELRLDVDEGVVVISEVADGSPADAAGFRAGDIILEVNGGRIERTKDLVAATRTPSRAWKVTVA
RGGRTITAVLGG

Sequences:

>Translated_492_residues
MGFAGVRSWVGAVLAGGLVVAGLSVAVAQQVERQAPAGPPAHAQAGTVVPSSAAAMKMSFAPVVARTAPAVVNVYALKIA
QRTNPFIDDPFFRRFFGGGPGGGGLGAPERVQRSLGSGVIVDPSGLVVTNQHVIQGADQIRIALNDKREFDAEVLLSDQR
TDLAVLRIKGEGAKFSSLEIGNSDELAVGDLVLAIGDPFGVGQTVTQGIVSALARTQVGVSDYQFFIQTDAAINPGNSGG
ALVDMDGRLVGINSAIYSRSGGSHGIGFAIPANMVKVVVASAKAGGKTVRRPWLGAKLQRVTPEIADSLGLQRPTGALVQ
SVATDGPAARAGLKTGDLIVAVEGQAIDDPESLNYRWGTRPLGGKANLGIVRQGRDQTLVVTLEPPPESVPRDEVVISSR
SPFAGARVLNVSPAVADELRLDVDEGVVVISEVADGSPADAAGFRAGDIILEVNGGRIERTKDLVAATRTPSRAWKVTVA
RGGRTITAVLGG
>Mature_491_residues
GFAGVRSWVGAVLAGGLVVAGLSVAVAQQVERQAPAGPPAHAQAGTVVPSSAAAMKMSFAPVVARTAPAVVNVYALKIAQ
RTNPFIDDPFFRRFFGGGPGGGGLGAPERVQRSLGSGVIVDPSGLVVTNQHVIQGADQIRIALNDKREFDAEVLLSDQRT
DLAVLRIKGEGAKFSSLEIGNSDELAVGDLVLAIGDPFGVGQTVTQGIVSALARTQVGVSDYQFFIQTDAAINPGNSGGA
LVDMDGRLVGINSAIYSRSGGSHGIGFAIPANMVKVVVASAKAGGKTVRRPWLGAKLQRVTPEIADSLGLQRPTGALVQS
VATDGPAARAGLKTGDLIVAVEGQAIDDPESLNYRWGTRPLGGKANLGIVRQGRDQTLVVTLEPPPESVPRDEVVISSRS
PFAGARVLNVSPAVADELRLDVDEGVVVISEVADGSPADAAGFRAGDIILEVNGGRIERTKDLVAATRTPSRAWKVTVAR
GGRTITAVLGG

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=346, Percent_Identity=32.9479768786127, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI4506141, Length=357, Percent_Identity=30.812324929972, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI24308541, Length=245, Percent_Identity=33.8775510204082, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI7019477, Length=341, Percent_Identity=32.258064516129, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1786356, Length=470, Percent_Identity=34.2553191489362, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1789629, Length=470, Percent_Identity=35.7446808510638, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1789630, Length=335, Percent_Identity=37.3134328358209, Blast_Score=186, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24646839, Length=284, Percent_Identity=32.3943661971831, Blast_Score=126, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 50652; Mature: 50521

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFAGVRSWVGAVLAGGLVVAGLSVAVAQQVERQAPAGPPAHAQAGTVVPSSAAAMKMSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEC
APVVARTAPAVVNVYALKIAQRTNPFIDDPFFRRFFGGGPGGGGLGAPERVQRSLGSGVI
CHHHHHCCCHHEEEEEEEEHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEE
VDPSGLVVTNQHVIQGADQIRIALNDKREFDAEVLLSDQRTDLAVLRIKGEGAKFSSLEI
ECCCCEEEECHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEC
GNSDELAVGDLVLAIGDPFGVGQTVTQGIVSALARTQVGVSDYQFFIQTDAAINPGNSGG
CCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCEECCCCCCC
ALVDMDGRLVGINSAIYSRSGGSHGIGFAIPANMVKVVVASAKAGGKTVRRPWLGAKLQR
EEEEECCEEEEECHHHEECCCCCCCCEEECHHHHHHHHEECCCCCCCHHCCCCCCCHHHH
VTPEIADSLGLQRPTGALVQSVATDGPAARAGLKTGDLIVAVEGQAIDDPESLNYRWGTR
CCHHHHHHHCCCCCHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCEECCCC
PLGGKANLGIVRQGRDQTLVVTLEPPPESVPRDEVVISSRSPFAGARVLNVSPAVADELR
CCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHE
LDVDEGVVVISEVADGSPADAAGFRAGDIILEVNGGRIERTKDLVAATRTPSRAWKVTVA
EECCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHCCCCCCCEEEEEEE
RGGRTITAVLGG
CCCEEEEEEECC
>Mature Secondary Structure 
GFAGVRSWVGAVLAGGLVVAGLSVAVAQQVERQAPAGPPAHAQAGTVVPSSAAAMKMSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEC
APVVARTAPAVVNVYALKIAQRTNPFIDDPFFRRFFGGGPGGGGLGAPERVQRSLGSGVI
CHHHHHCCCHHEEEEEEEEHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEE
VDPSGLVVTNQHVIQGADQIRIALNDKREFDAEVLLSDQRTDLAVLRIKGEGAKFSSLEI
ECCCCEEEECHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEC
GNSDELAVGDLVLAIGDPFGVGQTVTQGIVSALARTQVGVSDYQFFIQTDAAINPGNSGG
CCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCEECCCCCCC
ALVDMDGRLVGINSAIYSRSGGSHGIGFAIPANMVKVVVASAKAGGKTVRRPWLGAKLQR
EEEEECCEEEEECHHHEECCCCCCCCEEECHHHHHHHHEECCCCCCCHHCCCCCCCHHHH
VTPEIADSLGLQRPTGALVQSVATDGPAARAGLKTGDLIVAVEGQAIDDPESLNYRWGTR
CCHHHHHHHCCCCCHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCEECCCC
PLGGKANLGIVRQGRDQTLVVTLEPPPESVPRDEVVISSRSPFAGARVLNVSPAVADELR
CCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHE
LDVDEGVVVISEVADGSPADAAGFRAGDIILEVNGGRIERTKDLVAATRTPSRAWKVTVA
EECCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHCCCCCCCEEEEEEE
RGGRTITAVLGG
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]