Click here to switch to the map view.

The map label for this gene is yvrD [H]

Identifier: 158424130

GI number: 158424130

Start: 2840237

End: 2840980

Strand: Direct

Name: yvrD [H]

Synonym: AZC_2506

Alternate gene names: 158424130

Gene position: 2840237-2840980 (Clockwise)

Preceding gene: 158424129

Following gene: 158424131

Centisome position: 52.89

GC content: 69.49

Gene sequence:

>744_bases
ATGGACCTCGATCTCAAGGGGCGTCGCGTCCTCATCACCGGCGGTTCAAAGGGCATCGGCGCGGCCTGTGCGCGCGTCTT
CCTGGGGGAAGGCGCCGGCGTGCTGCTCGCCGCCCGTGACGAACGCCAGCTCGCCGCAACCGCCGCCGACCTCTCCGGCC
TCGGCCCCGTCGCCACCTGGGCCGGAGACCTTTCGCGCGCCGAGGAGCGGGAGCGGCTGCACCGGGAAGCGGATGGCTAC
GACATTCTCGTCAACAATGCCGGGGCGATCCCGCGCGGCGGCCTGCTCGACATGACCATGGAGCAGTGGGAAGCCGCCTG
GGCCCTGAAGGTGATGGGCTATATCCACCTGACCCAGCTCGCGCTCGGGACCATGAAGGCGCGGGGAAGCGGCGTCATCG
TCAACATCATCGGACAGGCCGGCCGCCAGCCGCGCTATGGCTATGTATGCGGCGCCACCGGCAATGCGGCGCTCATGGCC
TTCACCCATGCGGTGGGCGGCAAGGCGCCGGATTTCGGGGTGCGCGTATTCGGCATCAATCCCTCTGGCACGCGAACCGA
GCGCATGGAGACATTGGCAGCACAGGAGGGCCGCACCATCGCCGATGTGGGCGCCAGCGCGCCCTTCGGCCGACTCGCCG
AGCCGCTGGAGATCGCCCGCACCACGGCCTTCCTCGCATCACCCGCCTGCGGCTATGTCAGCGGGACGGTCCTCGATATT
GACGGCGGCGCAGGGTCGCACTGA

Upstream 100 bases:

>100_bases
TATGGTGGATGCGCTGGCCGCCTCGCCCGAAGTGGCCTTCGTCACCGGCAGCCAGATCTGCGACTGGTTCACCACCGCCG
CTTCCCCGGAGAGCTGACCC

Downstream 100 bases:

>100_bases
ACGAGGCACATTCTTTTACCATTTGGCGCCACGATCGCCTTGTCTCGGACATCGGAACTGCTAACGTCTCGTATCGCCTC
CGGTATTCAGCGGCGTTCGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MDLDLKGRRVLITGGSKGIGAACARVFLGEGAGVLLAARDERQLAATAADLSGLGPVATWAGDLSRAEERERLHREADGY
DILVNNAGAIPRGGLLDMTMEQWEAAWALKVMGYIHLTQLALGTMKARGSGVIVNIIGQAGRQPRYGYVCGATGNAALMA
FTHAVGGKAPDFGVRVFGINPSGTRTERMETLAAQEGRTIADVGASAPFGRLAEPLEIARTTAFLASPACGYVSGTVLDI
DGGAGSH

Sequences:

>Translated_247_residues
MDLDLKGRRVLITGGSKGIGAACARVFLGEGAGVLLAARDERQLAATAADLSGLGPVATWAGDLSRAEERERLHREADGY
DILVNNAGAIPRGGLLDMTMEQWEAAWALKVMGYIHLTQLALGTMKARGSGVIVNIIGQAGRQPRYGYVCGATGNAALMA
FTHAVGGKAPDFGVRVFGINPSGTRTERMETLAAQEGRTIADVGASAPFGRLAEPLEIARTTAFLASPACGYVSGTVLDI
DGGAGSH
>Mature_247_residues
MDLDLKGRRVLITGGSKGIGAACARVFLGEGAGVLLAARDERQLAATAADLSGLGPVATWAGDLSRAEERERLHREADGY
DILVNNAGAIPRGGLLDMTMEQWEAAWALKVMGYIHLTQLALGTMKARGSGVIVNIIGQAGRQPRYGYVCGATGNAALMA
FTHAVGGKAPDFGVRVFGINPSGTRTERMETLAAQEGRTIADVGASAPFGRLAEPLEIARTTAFLASPACGYVSGTVLDI
DGGAGSH

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=27.2357723577236, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=27.8884462151394, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=28.6290322580645, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=27.3109243697479, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723191, Length=178, Percent_Identity=29.2134831460674, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=27.3469387755102, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=31.9230769230769, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=30.859375, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=30.952380952381, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=28.3950617283951, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.5275590551181, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=25.609756097561, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=28.515625, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789208, Length=169, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=28.8065843621399, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=28.6885245901639, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=29.4354838709677, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=27.6679841897233, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=27.3809523809524, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=29.4573643410853, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=27.3469387755102, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=32.421875, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=29.5019157088123, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=28.8461538461538, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=29.8850574712644, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=26.7399267399267, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=27.3076923076923, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=140, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=30.0751879699248, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=30.3501945525292, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=33.0612244897959, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.8, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=29.6747967479675, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=26.9076305220884, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=26.9387755102041, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=27.0161290322581, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=31.1284046692607, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=27.3469387755102, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25581; Mature: 25581

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDLKGRRVLITGGSKGIGAACARVFLGEGAGVLLAARDERQLAATAADLSGLGPVATW
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHH
AGDLSRAEERERLHREADGYDILVNNAGAIPRGGLLDMTMEQWEAAWALKVMGYIHLTQL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGTMKARGSGVIVNIIGQAGRQPRYGYVCGATGNAALMAFTHAVGGKAPDFGVRVFGIN
HHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCCEEHEEEHHHHCCCCCCCCEEEEEEC
PSGTRTERMETLAAQEGRTIADVGASAPFGRLAEPLEIARTTAFLASPACGYVSGTVLDI
CCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEE
DGGAGSH
CCCCCCC
>Mature Secondary Structure
MDLDLKGRRVLITGGSKGIGAACARVFLGEGAGVLLAARDERQLAATAADLSGLGPVATW
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHH
AGDLSRAEERERLHREADGYDILVNNAGAIPRGGLLDMTMEQWEAAWALKVMGYIHLTQL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGTMKARGSGVIVNIIGQAGRQPRYGYVCGATGNAALMAFTHAVGGKAPDFGVRVFGIN
HHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCCEEHEEEHHHHCCCCCCCCEEEEEEC
PSGTRTERMETLAAQEGRTIADVGASAPFGRLAEPLEIARTTAFLASPACGYVSGTVLDI
CCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEE
DGGAGSH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]