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The map label for this gene is mgtC [H]

Identifier: 158423937

GI number: 158423937

Start: 2637638

End: 2638354

Strand: Direct

Name: mgtC [H]

Synonym: AZC_2313

Alternate gene names: 158423937

Gene position: 2637638-2638354 (Clockwise)

Preceding gene: 158423936

Following gene: 158423942

Centisome position: 49.12

GC content: 67.22

Gene sequence:

>717_bases
ATGAAGTTCATAGAAAGCTTTCACCTCCTGCCTTTCCTCGACACGGTGGTCAGCTATGTGGCGGCCTTCGTGTGCGGCGC
GCTGATCGGTGCGGAACGGCAGTATCGCCAGCGCACTGCCGGCCTGCGCACCAATGTCCTCGTGGCCATCGGCGCTGCGG
GCTTCACGGATCTTGCGCAGGGCATAGCGGGGGATGTGGAGGCGGTCCGCGTCATCTCCTATGTGGTCTCGGGCATCGGC
TTTCTGGGTGCCGGCGTGATCATGAAGGAGGGGCTGAACGTGCGCGGCCTCAACACGGCGGCAACGCTCTGGTGCTCGGC
CGCCGTGGGCGCCTGCGCAGGCGTGGACCGGCTGGCCGAAGCCTTCCTCCTGACGGTCTTCGTCATCGCCGGCAACACGC
TGCTGCGGCCGCTGGTGAACGCCATCAACCGCATTCCCATCAAGGCGGAGAGCATCGAGGCGACCTATACGGTCAGCCTC
ACCACGGCGGTGGAGCAGGCGGGCGTGATGCGCGACCTGCTGGAGGAGCGGCTGGAGGCCGCGAGCTATCCGGTGGCCGA
ACTGGAGGTGGTGGAGCGCGGCGAGGAGCAGGTGGAGATCGTCGCCACCCTCACCTCGACGGAGGTGGAGGGCGAGGAAC
TCGACGCCGTGGTGGAGGGCCTCCTCACCCGTCCCCACGTGGACCACGCCACGTGGAGCGCCAACACGCAGTCCTGA

Upstream 100 bases:

>100_bases
GAGCGGCGCCCTTTTCGTTTGCGGCGGCTCGCGGATTGCGGCAAGGCTCCCGCTCGCCGGGGTGTCATCTCCTGGTCATG
AAGCGTGGCTATCGGGCGGC

Downstream 100 bases:

>100_bases
ACCCGTCTGCCTTCTCCGCCGGGATCAGGCGGCGATGCGCCAATCGGTCACGCGCAGCGACAGGCCGTGTTCCGGGTCCC
AGTTCGCGGGTACGGAGAGG

Product: MgtC/SapB transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKFIESFHLLPFLDTVVSYVAAFVCGALIGAERQYRQRTAGLRTNVLVAIGAAGFTDLAQGIAGDVEAVRVISYVVSGIG
FLGAGVIMKEGLNVRGLNTAATLWCSAAVGACAGVDRLAEAFLLTVFVIAGNTLLRPLVNAINRIPIKAESIEATYTVSL
TTAVEQAGVMRDLLEERLEAASYPVAELEVVERGEEQVEIVATLTSTEVEGEELDAVVEGLLTRPHVDHATWSANTQS

Sequences:

>Translated_238_residues
MKFIESFHLLPFLDTVVSYVAAFVCGALIGAERQYRQRTAGLRTNVLVAIGAAGFTDLAQGIAGDVEAVRVISYVVSGIG
FLGAGVIMKEGLNVRGLNTAATLWCSAAVGACAGVDRLAEAFLLTVFVIAGNTLLRPLVNAINRIPIKAESIEATYTVSL
TTAVEQAGVMRDLLEERLEAASYPVAELEVVERGEEQVEIVATLTSTEVEGEELDAVVEGLLTRPHVDHATWSANTQS
>Mature_238_residues
MKFIESFHLLPFLDTVVSYVAAFVCGALIGAERQYRQRTAGLRTNVLVAIGAAGFTDLAQGIAGDVEAVRVISYVVSGIG
FLGAGVIMKEGLNVRGLNTAATLWCSAAVGACAGVDRLAEAFLLTVFVIAGNTLLRPLVNAINRIPIKAESIEATYTVSL
TTAVEQAGVMRDLLEERLEAASYPVAELEVVERGEEQVEIVATLTSTEVEGEELDAVVEGLLTRPHVDHATWSANTQS

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=103, Percent_Identity=42.7184466019417, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25264; Mature: 25264

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIESFHLLPFLDTVVSYVAAFVCGALIGAERQYRQRTAGLRTNVLVAIGAAGFTDLAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCHHHHHH
GIAGDVEAVRVISYVVSGIGFLGAGVIMKEGLNVRGLNTAATLWCSAAVGACAGVDRLAE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AFLLTVFVIAGNTLLRPLVNAINRIPIKAESIEATYTVSLTTAVEQAGVMRDLLEERLEA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
ASYPVAELEVVERGEEQVEIVATLTSTEVEGEELDAVVEGLLTRPHVDHATWSANTQS
HCCCHHHHHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFIESFHLLPFLDTVVSYVAAFVCGALIGAERQYRQRTAGLRTNVLVAIGAAGFTDLAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCHHHHHH
GIAGDVEAVRVISYVVSGIGFLGAGVIMKEGLNVRGLNTAATLWCSAAVGACAGVDRLAE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AFLLTVFVIAGNTLLRPLVNAINRIPIKAESIEATYTVSLTTAVEQAGVMRDLLEERLEA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
ASYPVAELEVVERGEEQVEIVATLTSTEVEGEELDAVVEGLLTRPHVDHATWSANTQS
HCCCHHHHHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA