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The map label for this gene is rfaC [H]

Identifier: 158423876

GI number: 158423876

Start: 2574765

End: 2575802

Strand: Direct

Name: rfaC [H]

Synonym: AZC_2252

Alternate gene names: 158423876

Gene position: 2574765-2575802 (Clockwise)

Preceding gene: 158423875

Following gene: 158423877

Centisome position: 47.95

GC content: 70.62

Gene sequence:

>1038_bases
ATGAAGGTTCTGGTCATCAAGCTCTCCTCGCTGGGCGATGTGGTGCACACCTTCCCGGCGGTCACGGACGCGGCTCGCCG
CCTGCCCGGGCTCGTGCTGGACTGGGCGGTGGAAGACGCCTTCGTGCCGCTGGTGAAGCTGCACCCTGCCGTGCGCCGGG
CCATTCCCGTGCCGCTGCGGCGCCTCAAGAAGAAGCCGCTCGCCGCCTTCCGGAGCGGCGAGGCGCAGGCGGTGGGCGCG
GCGCTGAAAGCCGAGCGCTATGACGTGGTCATCGATGCGCAGGGCCTCATGAAGAGCGCCGCCGTCGGCCTCTTCACCCA
CGGCCGGCGCCATGGCTTCGATCGCGCCACCGCGCGCGAAGGGCTCGCCAGCCTCACCTATGCCAAGGGCCATCATCTGC
CGGAGCGCGAGCATATGGCTCTGCGCATCCGCAAGCTGTTCGCTGGCGCGCTCGGCTACAGCCTCGATGGGCTGGAGGCG
GACGCGGGGCTAGTCACGGCGCCGCCGCCCGCCGGGCCGCCCTATTGGGTGTTCCTGCATGGCACGACCTGGGGCACCAA
GACCTGGACCGTGAGACACTGGCGGGAACTTGCCGCCCGTGCGGCCCGGGCCGGACGTGAGGTGAAGATCTTCGCCCACG
GCGCGCAGGAGGAAGAGCGGGCCTCTGCCATCGCTGCCGAGCTGCCGAATGTGGAGCGGATGCCGCCCCTCGGCCTCGAC
GCGGTGGCACCCGTGCTGGCCGGTGCGGAGGCGGTGGTGACGGTGGATACGGGCCTTGGGCATCTGGCTGCGGCGCTGGG
CGTGCCCACCGTCGGCCTTTATGGGCCGACCAATCCGCGCCTTACCGGCCTTTATGGTCCGAAAGTGCTGGAGCTGCGCT
CCCTGCGCGACTGCGCCCCGTGCGAGAAGCAGACCTGCCGCATTGCGCCCGACCGCGCCGAGGGACCGCCCTGCCTTGCG
GACTTCACCGGCCGCGACATCTGGCGGGCCATCAGCCTGCTGCGGCTCGGCCATGCCGACGCCATGGACAAGATGTGA

Upstream 100 bases:

>100_bases
CGGGAATGCCCGCTCGGGACGCTCGCCTGTTTCGAGGCCATCAGCCCGCAGGAAGTGCTGGCCGCCGCCATGGCGGTGCA
GGGATGAGCGTCCGGCTGCC

Downstream 100 bases:

>100_bases
GGGCGGAGGGATAAGAGGCGCGTTTCAAACGAGGCCGAGTTCCCGATGTCCCATTCTGCCGCCGGTGCCCGCGATACCAT
TCTCGTGACCGGAGGTGCCG

Product: lipopolysaccharide heptosyltransferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKVLVIKLSSLGDVVHTFPAVTDAARRLPGLVLDWAVEDAFVPLVKLHPAVRRAIPVPLRRLKKKPLAAFRSGEAQAVGA
ALKAERYDVVIDAQGLMKSAAVGLFTHGRRHGFDRATAREGLASLTYAKGHHLPEREHMALRIRKLFAGALGYSLDGLEA
DAGLVTAPPPAGPPYWVFLHGTTWGTKTWTVRHWRELAARAARAGREVKIFAHGAQEEERASAIAAELPNVERMPPLGLD
AVAPVLAGAEAVVTVDTGLGHLAAALGVPTVGLYGPTNPRLTGLYGPKVLELRSLRDCAPCEKQTCRIAPDRAEGPPCLA
DFTGRDIWRAISLLRLGHADAMDKM

Sequences:

>Translated_345_residues
MKVLVIKLSSLGDVVHTFPAVTDAARRLPGLVLDWAVEDAFVPLVKLHPAVRRAIPVPLRRLKKKPLAAFRSGEAQAVGA
ALKAERYDVVIDAQGLMKSAAVGLFTHGRRHGFDRATAREGLASLTYAKGHHLPEREHMALRIRKLFAGALGYSLDGLEA
DAGLVTAPPPAGPPYWVFLHGTTWGTKTWTVRHWRELAARAARAGREVKIFAHGAQEEERASAIAAELPNVERMPPLGLD
AVAPVLAGAEAVVTVDTGLGHLAAALGVPTVGLYGPTNPRLTGLYGPKVLELRSLRDCAPCEKQTCRIAPDRAEGPPCLA
DFTGRDIWRAISLLRLGHADAMDKM
>Mature_345_residues
MKVLVIKLSSLGDVVHTFPAVTDAARRLPGLVLDWAVEDAFVPLVKLHPAVRRAIPVPLRRLKKKPLAAFRSGEAQAVGA
ALKAERYDVVIDAQGLMKSAAVGLFTHGRRHGFDRATAREGLASLTYAKGHHLPEREHMALRIRKLFAGALGYSLDGLEA
DAGLVTAPPPAGPPYWVFLHGTTWGTKTWTVRHWRELAARAARAGREVKIFAHGAQEEERASAIAAELPNVERMPPLGLD
AVAPVLAGAEAVVTVDTGLGHLAAALGVPTVGLYGPTNPRLTGLYGPKVLELRSLRDCAPCEKQTCRIAPDRAEGPPCLA
DFTGRDIWRAISLLRLGHADAMDKM

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=302, Percent_Identity=46.6887417218543, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.4.1.-

Molecular weight: Translated: 37100; Mature: 37100

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVIKLSSLGDVVHTFPAVTDAARRLPGLVLDWAVEDAFVPLVKLHPAVRRAIPVPLR
CEEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCHHHHHHCCHHHH
RLKKKPLAAFRSGEAQAVGAALKAERYDVVIDAQGLMKSAAVGLFTHGRRHGFDRATARE
HHCCCCHHHHHCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHH
GLASLTYAKGHHLPEREHMALRIRKLFAGALGYSLDGLEADAGLVTAPPPAGPPYWVFLH
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCEEEEEE
GTTWGTKTWTVRHWRELAARAARAGREVKIFAHGAQEEERASAIAAELPNVERMPPLGLD
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHH
AVAPVLAGAEAVVTVDTGLGHLAAALGVPTVGLYGPTNPRLTGLYGPKVLELRSLRDCAP
HHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEECCCCCCCEEECCCCCHHHHHHHHCCCC
CEKQTCRIAPDRAEGPPCLADFTGRDIWRAISLLRLGHADAMDKM
CCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MKVLVIKLSSLGDVVHTFPAVTDAARRLPGLVLDWAVEDAFVPLVKLHPAVRRAIPVPLR
CEEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCHHHHHHCCHHHH
RLKKKPLAAFRSGEAQAVGAALKAERYDVVIDAQGLMKSAAVGLFTHGRRHGFDRATARE
HHCCCCHHHHHCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHH
GLASLTYAKGHHLPEREHMALRIRKLFAGALGYSLDGLEADAGLVTAPPPAGPPYWVFLH
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCEEEEEE
GTTWGTKTWTVRHWRELAARAARAGREVKIFAHGAQEEERASAIAAELPNVERMPPLGLD
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHH
AVAPVLAGAEAVVTVDTGLGHLAAALGVPTVGLYGPTNPRLTGLYGPKVLELRSLRDCAP
HHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEECCCCCCCEEECCCCCHHHHHHHHCCCC
CEKQTCRIAPDRAEGPPCLADFTGRDIWRAISLLRLGHADAMDKM
CCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8478319; 8041620; 9278503; 1624462 [H]