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The map label for this gene is ctaA

Identifier: 158423808

GI number: 158423808

Start: 2500302

End: 2501351

Strand: Reverse

Name: ctaA

Synonym: AZC_2184

Alternate gene names: 158423808

Gene position: 2501351-2500302 (Counterclockwise)

Preceding gene: 158423810

Following gene: 158423805

Centisome position: 46.58

GC content: 67.71

Gene sequence:

>1050_bases
ATGGCTCTCGCCGGCGCGCCTGTCGCGGCGCGGTCACCTCGCGCGGTCCAGGTCTGGCTCTATGCGGTGGCCGCCCTCAT
CGTGCTGATGGTGGTGGTGGGCGGCGCGACCCGCCTCACCGAATCCGGCCTCTCCATCACCGAGTGGAAGCCGATAACGG
GCGCCCTGCCACCGCTCTCGGAGGCGGACTGGCAGGCCGAGTTCGACCGCTACAAGACCATTCCCCAGTATGAAATCCTC
AACAAGGGCATGGGCCTCGAAGCCTTCAAGACCATCTATTGGTGGGAATGGGGCCATCGCCTGCTCGGCCGTGTCATCGG
CCTCGCCTTCTTCCTCCCCTTCCTCTATTTCGCGCTGACCGGCGCCCTGCGCGGCACTTTGCTCGCCCGCTGCTTCGGAC
TGTTCCTGCTCGGCGGTCTTCAGGGCGCGGTGGGCTGGTGGATGGTGGCCTCGGGCCTCACGGAGCACACGTCCGTCAGC
CAGTATCGCCTCGCCGTCCACCTGACGCTCGCGTGCATCATCCTCACCGCCATCGTTGCCGTGGCCCGCAGCCTTTCCCC
TCTTGCTGCGCAGGCCCTGCCCGCTCGCGTGCGGCTGACGGCGCGTGTGCTGGTCGGCCTTGTCCTGCTCCAGATCTTCG
CCGGCGGCCTCGTGGCCGGCCTCGATGCCGGCATGTCCTTCAACACCTGGCCGCTGATGGACGGCCATCTGGTGCCCGCC
GCGGGCCAGCTCGGCGCCATGCAGCCGCTGTGGCGCAATCTCTTCGAGAACGCGATGACGGTTCAGTTCGTGCACCGGAG
CATCGCCTATCTCATCTTCGCGCTGGCCTTCCTGCACCTTCTGGATTGCCTCCGCCTCGGCGGCACCGCCGCCCGCCGCG
CCACGCTTGTGTTCGCGCTGGTGGCAGCTCAGGCGATGCTCGGCATTCTGACGCTGGTGCATATGGTGCCGCTCGATCTG
GCGCTGGCCCATCAACTGGGCGCGACGCTGGTGCTCATCGCGGCCATGATCCACGCCAGCGACAGCAACCGCCGCCAGAT
CGTGGCCTGA

Upstream 100 bases:

>100_bases
CGACCGCGCGCCGCCTTGCACGGCCCCTTGCTGCTCTATAACGGAACGCAGGGGGCAGGAATATCGAGGAGAAGGGAAAC
CGATGTCGCAGGCACAAGGC

Downstream 100 bases:

>100_bases
GCCCAAGACGCAACAAACGAAACCGCCCGCGCAGCGGCACCTGCGCGGGCGGTTCTGCCGATCGGGGATCAGGCGGGCGC
GGAGATGCGCCTCAGCCCAT

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MALAGAPVAARSPRAVQVWLYAVAALIVLMVVVGGATRLTESGLSITEWKPITGALPPLSEADWQAEFDRYKTIPQYEIL
NKGMGLEAFKTIYWWEWGHRLLGRVIGLAFFLPFLYFALTGALRGTLLARCFGLFLLGGLQGAVGWWMVASGLTEHTSVS
QYRLAVHLTLACIILTAIVAVARSLSPLAAQALPARVRLTARVLVGLVLLQIFAGGLVAGLDAGMSFNTWPLMDGHLVPA
AGQLGAMQPLWRNLFENAMTVQFVHRSIAYLIFALAFLHLLDCLRLGGTAARRATLVFALVAAQAMLGILTLVHMVPLDL
ALAHQLGATLVLIAAMIHASDSNRRQIVA

Sequences:

>Translated_349_residues
MALAGAPVAARSPRAVQVWLYAVAALIVLMVVVGGATRLTESGLSITEWKPITGALPPLSEADWQAEFDRYKTIPQYEIL
NKGMGLEAFKTIYWWEWGHRLLGRVIGLAFFLPFLYFALTGALRGTLLARCFGLFLLGGLQGAVGWWMVASGLTEHTSVS
QYRLAVHLTLACIILTAIVAVARSLSPLAAQALPARVRLTARVLVGLVLLQIFAGGLVAGLDAGMSFNTWPLMDGHLVPA
AGQLGAMQPLWRNLFENAMTVQFVHRSIAYLIFALAFLHLLDCLRLGGTAARRATLVFALVAAQAMLGILTLVHMVPLDL
ALAHQLGATLVLIAAMIHASDSNRRQIVA
>Mature_348_residues
ALAGAPVAARSPRAVQVWLYAVAALIVLMVVVGGATRLTESGLSITEWKPITGALPPLSEADWQAEFDRYKTIPQYEILN
KGMGLEAFKTIYWWEWGHRLLGRVIGLAFFLPFLYFALTGALRGTLLARCFGLFLLGGLQGAVGWWMVASGLTEHTSVSQ
YRLAVHLTLACIILTAIVAVARSLSPLAAQALPARVRLTARVLVGLVLLQIFAGGLVAGLDAGMSFNTWPLMDGHLVPAA
GQLGAMQPLWRNLFENAMTVQFVHRSIAYLIFALAFLHLLDCLRLGGTAARRATLVFALVAAQAMLGILTLVHMVPLDLA
LAHQLGATLVLIAAMIHASDSNRRQIVA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=336, Percent_Identity=38.6904761904762, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI17921987, Length=264, Percent_Identity=40.9090909090909, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17536069, Length=359, Percent_Identity=36.2116991643454, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320989, Length=380, Percent_Identity=37.8947368421053, Blast_Score=232, Evalue=6e-62,
Organism=Drosophila melanogaster, GI19922860, Length=346, Percent_Identity=35.5491329479769, Blast_Score=185, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_AZOC5 (A8I7Y5)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001525100.1
- GeneID:   5691016
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_2184
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- ProtClustDB:   CLSK2793705
- BioCyc:   ACAU438753:AZC_2184-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 37624; Mature: 37493

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: BINDING 324-324

Signals:

None

Transmembrane regions:

HASH(0x1fd5f864)-; HASH(0x20a9c5f4)-; HASH(0x1fb38350)-; HASH(0x20667e9c)-; HASH(0x20377f28)-; HASH(0x20a6d7c8)-; HASH(0x20aa534c)-; HASH(0x20aa53e8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAGAPVAARSPRAVQVWLYAVAALIVLMVVVGGATRLTESGLSITEWKPITGALPPLS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCC
EADWQAEFDRYKTIPQYEILNKGMGLEAFKTIYWWEWGHRLLGRVIGLAFFLPFLYFALT
CCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALRGTLLARCFGLFLLGGLQGAVGWWMVASGLTEHTSVSQYRLAVHLTLACIILTAIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VARSLSPLAAQALPARVRLTARVLVGLVLLQIFAGGLVAGLDAGMSFNTWPLMDGHLVPA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
AGQLGAMQPLWRNLFENAMTVQFVHRSIAYLIFALAFLHLLDCLRLGGTAARRATLVFAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VAAQAMLGILTLVHMVPLDLALAHQLGATLVLIAAMIHASDSNRRQIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
>Mature Secondary Structure 
ALAGAPVAARSPRAVQVWLYAVAALIVLMVVVGGATRLTESGLSITEWKPITGALPPLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCC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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA