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The map label for this gene is dadA [C]

Identifier: 158423648

GI number: 158423648

Start: 2334535

End: 2335860

Strand: Reverse

Name: dadA [C]

Synonym: AZC_2024

Alternate gene names: 158423648

Gene position: 2335860-2334535 (Counterclockwise)

Preceding gene: 158423649

Following gene: 158423643

Centisome position: 43.5

GC content: 70.74

Gene sequence:

>1326_bases
ATGCCCATTCAGCTTCTCTCGATCGAAACCAGCCCCGAACTGCCGACAGAGGCCGATGTGGTCGTCATCGGGGGCGGAGT
GGTGGGCGTGTTCAGCGCCTATTATCTCGCCCGGCGCGGGGTGAAGGTGGCGCTGGTGGAGAAAGGCCGGATCGCCGCCG
AACAGTCCAGCCGGAACTGGGGCTGGTGCCGCCAGCAGAACCGCGACGCCCGTGAACTGCCACTGGCCACCAAAAGCCTT
GATCTGTGGGAGCGCCTTGCGGCCGAGACCGGCGAGGATGCCGGCTTCCGCCGCTGCGGCCTGCTCTATCTCTCCGACGA
TGAGGCGGAGATCGCTGGCTGGGCGAAATGGGGCGAATTCGCCCGCAGCGTCGGCGTGACCACCCACATGCTGGATGCCC
GCGAAGCGACGGCACGGGGCGCGGCGAGCGGCCGGTCATGGAAGGGCGGCGTCTTTTCGCCGACCGACGGCACGGCCGAT
CCCGGACGGGCCGTGCCCATCGCCGCCCGCGGCATCCTGGCGGCGGGCGGCAGCGTTCATCAGATGTGCGCGGCGCGCGG
GCTGGAGACGCAGGGCGGCCGCGTCAGCGCCGTGGTGACGGAGAAGGGCACCATCCGCACCAGGACGGTCGTGCTGGCGG
GCGGAGCGTGGGCCTCATCCTTCTGCCGGCAGTATGGCATCCGCTTTCCGCAGGCTTCGATCCGGGCCTCGATCCTCTCC
GTCGGCCCCGGCCCCGAAGAGCTGCCGGCCGCACTTCACACCAAGGCCGTCTCGGTGACCCGGCGGAGCGACGGCAGGTA
TACGCTCGCCATCAGTGGCGGCGCCCGGCTGGACCCGACGCCGCAGCAGTTCCGCTACTGGCGGGAATTCCTGCCGATGT
TCGCCAAGCGCTGGCGCAGCCTCGCGCCGGGCGGGCTCGAAGGCTGGCGCTCGGGCCACGAGACGCTGGCCCGCTGGCGT
CTCGATGCGCCGACGCCCATGGAAGCCTGCCGCATCCTCGATCCGGTGCCGAACGCGCGCCAGCTCAGCGAAACCCACGC
CCGCGCCGTTCACCTGCTGCCGGCCCTGCGCAACCGGCCGGTGACCGCCCAATGGGCGAGCTATATCGACAGCACGCCGG
ACGGCGTCCCGGCCATTGGTGAGGTGGACAGCCTGCCCGGCTTCATCCTCGCCGCGGGCTTCAGCGGGCACGGATTTGGC
ATCGGCACCGGCGCCGGGCACCTGATCGCCGATCTCGTCACCGGGACCGCTCCCATCGTCGACCCCAGACCCTATAGCCC
GGCCCGCTTCAGCAAGGGGGCCTGGGGCAAGGTGGCCGAGTTCTGA

Upstream 100 bases:

>100_bases
GCCCCGCAGAAGGAAATGCTGCGTGCGGGCCGTTTGCGGTGCCGGCCCGCTGGTGCCGCCCGCTAACATCGGCAGGACGA
TTCACGGAACGGTCCGCCGC

Downstream 100 bases:

>100_bases
GGGCAGCCCGCCGGCATCAGGCCGCCGCGCGGGCGCCGGTCCAGCGGCTCGGGCTGAACGGTGCCGGATCGGCGCAGGTG
GCCTCGCCGGACATCATCTG

Product: glycine/D-amino acid oxidases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPIQLLSIETSPELPTEADVVVIGGGVVGVFSAYYLARRGVKVALVEKGRIAAEQSSRNWGWCRQQNRDARELPLATKSL
DLWERLAAETGEDAGFRRCGLLYLSDDEAEIAGWAKWGEFARSVGVTTHMLDAREATARGAASGRSWKGGVFSPTDGTAD
PGRAVPIAARGILAAGGSVHQMCAARGLETQGGRVSAVVTEKGTIRTRTVVLAGGAWASSFCRQYGIRFPQASIRASILS
VGPGPEELPAALHTKAVSVTRRSDGRYTLAISGGARLDPTPQQFRYWREFLPMFAKRWRSLAPGGLEGWRSGHETLARWR
LDAPTPMEACRILDPVPNARQLSETHARAVHLLPALRNRPVTAQWASYIDSTPDGVPAIGEVDSLPGFILAAGFSGHGFG
IGTGAGHLIADLVTGTAPIVDPRPYSPARFSKGAWGKVAEF

Sequences:

>Translated_441_residues
MPIQLLSIETSPELPTEADVVVIGGGVVGVFSAYYLARRGVKVALVEKGRIAAEQSSRNWGWCRQQNRDARELPLATKSL
DLWERLAAETGEDAGFRRCGLLYLSDDEAEIAGWAKWGEFARSVGVTTHMLDAREATARGAASGRSWKGGVFSPTDGTAD
PGRAVPIAARGILAAGGSVHQMCAARGLETQGGRVSAVVTEKGTIRTRTVVLAGGAWASSFCRQYGIRFPQASIRASILS
VGPGPEELPAALHTKAVSVTRRSDGRYTLAISGGARLDPTPQQFRYWREFLPMFAKRWRSLAPGGLEGWRSGHETLARWR
LDAPTPMEACRILDPVPNARQLSETHARAVHLLPALRNRPVTAQWASYIDSTPDGVPAIGEVDSLPGFILAAGFSGHGFG
IGTGAGHLIADLVTGTAPIVDPRPYSPARFSKGAWGKVAEF
>Mature_440_residues
PIQLLSIETSPELPTEADVVVIGGGVVGVFSAYYLARRGVKVALVEKGRIAAEQSSRNWGWCRQQNRDARELPLATKSLD
LWERLAAETGEDAGFRRCGLLYLSDDEAEIAGWAKWGEFARSVGVTTHMLDAREATARGAASGRSWKGGVFSPTDGTADP
GRAVPIAARGILAAGGSVHQMCAARGLETQGGRVSAVVTEKGTIRTRTVVLAGGAWASSFCRQYGIRFPQASIRASILSV
GPGPEELPAALHTKAVSVTRRSDGRYTLAISGGARLDPTPQQFRYWREFLPMFAKRWRSLAPGGLEGWRSGHETLARWRL
DAPTPMEACRILDPVPNARQLSETHARAVHLLPALRNRPVTAQWASYIDSTPDGVPAIGEVDSLPGFILAAGFSGHGFGI
GTGAGHLIADLVTGTAPIVDPRPYSPARFSKGAWGKVAEF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=427, Percent_Identity=25.5269320843091, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI21361378, Length=427, Percent_Identity=25.5269320843091, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI194306651, Length=419, Percent_Identity=22.673031026253, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI24797151, Length=437, Percent_Identity=22.6544622425629, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20130091, Length=440, Percent_Identity=24.0909090909091, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28571104, Length=437, Percent_Identity=24.0274599542334, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 47185; Mature: 47054

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQLLSIETSPELPTEADVVVIGGGVVGVFSAYYLARRGVKVALVEKGRIAAEQSSRNW
CCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCEEHHCCCCCC
GWCRQQNRDARELPLATKSLDLWERLAAETGEDAGFRRCGLLYLSDDEAEIAGWAKWGEF
CCHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
ARSVGVTTHMLDAREATARGAASGRSWKGGVFSPTDGTADPGRAVPIAARGILAAGGSVH
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHCCCHHH
QMCAARGLETQGGRVSAVVTEKGTIRTRTVVLAGGAWASSFCRQYGIRFPQASIRASILS
HHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHEE
VGPGPEELPAALHTKAVSVTRRSDGRYTLAISGGARLDPTPQQFRYWREFLPMFAKRWRS
CCCCHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAPGGLEGWRSGHETLARWRLDAPTPMEACRILDPVPNARQLSETHARAVHLLPALRNRP
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VTAQWASYIDSTPDGVPAIGEVDSLPGFILAAGFSGHGFGIGTGAGHLIADLVTGTAPIV
CCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHHHHCCCCCC
DPRPYSPARFSKGAWGKVAEF
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PIQLLSIETSPELPTEADVVVIGGGVVGVFSAYYLARRGVKVALVEKGRIAAEQSSRNW
CEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCEEHHCCCCCC
GWCRQQNRDARELPLATKSLDLWERLAAETGEDAGFRRCGLLYLSDDEAEIAGWAKWGEF
CCHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
ARSVGVTTHMLDAREATARGAASGRSWKGGVFSPTDGTADPGRAVPIAARGILAAGGSVH
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHCCCHHH
QMCAARGLETQGGRVSAVVTEKGTIRTRTVVLAGGAWASSFCRQYGIRFPQASIRASILS
HHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHEE
VGPGPEELPAALHTKAVSVTRRSDGRYTLAISGGARLDPTPQQFRYWREFLPMFAKRWRS
CCCCHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAPGGLEGWRSGHETLARWRLDAPTPMEACRILDPVPNARQLSETHARAVHLLPALRNRP
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VTAQWASYIDSTPDGVPAIGEVDSLPGFILAAGFSGHGFGIGTGAGHLIADLVTGTAPIV
CCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHHHHCCCCCC
DPRPYSPARFSKGAWGKVAEF
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8682785; 10984043; 8097014 [H]