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The map label for this gene is asnC [H]

Identifier: 158423649

GI number: 158423649

Start: 2335999

End: 2336481

Strand: Reverse

Name: asnC [H]

Synonym: AZC_2025

Alternate gene names: 158423649

Gene position: 2336481-2335999 (Counterclockwise)

Preceding gene: 158423650

Following gene: 158423648

Centisome position: 43.51

GC content: 58.59

Gene sequence:

>483_bases
ATGAAACTCGACCAGATCGACGTCAAGATCCTCTCCGAGCTGCAGAAGAACGGCCGCATCACCAATGTGGAGCTGGCCGG
GCTGGTCAACCTGTCTCCCAGTCCCTGCCTGATGCGGATGAAGAAGCTCCAGTCCGAGGGCTACATCACCGGCTATTCGG
CCCGCATCAATGTGGGCAAGCTCGGGCAGACGCTCACCGTCTTCACGGAAGTCACCTTGAAGAACCACAGGCAGATCGAC
TTCGCCCGCTTCGTGGCGGCCGTGGACAAGCTCGACAGCGTGATGGAGTGCCACCTGATCTCCGGCGGCTATGACTACCT
CGTGAAATTCGTGACGCGCGGCATCGCCGATTATCAGGAAACCATGGAACGCCTGATCGATCAGGATATCGGGATCGACA
AATACTTCAGCTTCGTGGTGCTGAAGTCGCCGATCGTGAAGACCCACATGCCCCTCACAAGCCTGTTCCGCCCGACCGAC
TGA

Upstream 100 bases:

>100_bases
CTGGAGCGCGATCCCGCGCTCGTGGCGGCGCTGTCGAAGCGATGAGGCCGGCGGGAGCGCGGGCGTTGCCTTGGGCCAGT
GCGGCGGGCATGGTCAGCAC

Downstream 100 bases:

>100_bases
CAGACGGCGCGGTCGGGCGAACATGCGGCACGCGTCCGGCCCCGCAGAAGGAAATGCTGCGTGCGGGCCGTTTGCGGTGC
CGGCCCGCTGGTGCCGCCCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKLDQIDVKILSELQKNGRITNVELAGLVNLSPSPCLMRMKKLQSEGYITGYSARINVGKLGQTLTVFTEVTLKNHRQID
FARFVAAVDKLDSVMECHLISGGYDYLVKFVTRGIADYQETMERLIDQDIGIDKYFSFVVLKSPIVKTHMPLTSLFRPTD

Sequences:

>Translated_160_residues
MKLDQIDVKILSELQKNGRITNVELAGLVNLSPSPCLMRMKKLQSEGYITGYSARINVGKLGQTLTVFTEVTLKNHRQID
FARFVAAVDKLDSVMECHLISGGYDYLVKFVTRGIADYQETMERLIDQDIGIDKYFSFVVLKSPIVKTHMPLTSLFRPTD
>Mature_160_residues
MKLDQIDVKILSELQKNGRITNVELAGLVNLSPSPCLMRMKKLQSEGYITGYSARINVGKLGQTLTVFTEVTLKNHRQID
FARFVAAVDKLDSVMECHLISGGYDYLVKFVTRGIADYQETMERLIDQDIGIDKYFSFVVLKSPIVKTHMPLTSLFRPTD

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=141, Percent_Identity=41.8439716312057, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=30, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790182, Length=151, Percent_Identity=31.1258278145695, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18105; Mature: 18105

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDQIDVKILSELQKNGRITNVELAGLVNLSPSPCLMRMKKLQSEGYITGYSARINVGK
CCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEEEHHH
LGQTLTVFTEVTLKNHRQIDFARFVAAVDKLDSVMECHLISGGYDYLVKFVTRGIADYQE
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TMERLIDQDIGIDKYFSFVVLKSPIVKTHMPLTSLFRPTD
HHHHHHHHCCCHHHHHHHHHHHCCHHHHCCCHHHHCCCCC
>Mature Secondary Structure
MKLDQIDVKILSELQKNGRITNVELAGLVNLSPSPCLMRMKKLQSEGYITGYSARINVGK
CCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEEEHHH
LGQTLTVFTEVTLKNHRQIDFARFVAAVDKLDSVMECHLISGGYDYLVKFVTRGIADYQE
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TMERLIDQDIGIDKYFSFVVLKSPIVKTHMPLTSLFRPTD
HHHHHHHHCCCHHHHHHHHHHHCCHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]