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The map label for this gene is appC [H]

Identifier: 158423608

GI number: 158423608

Start: 2287175

End: 2288125

Strand: Reverse

Name: appC [H]

Synonym: AZC_1984

Alternate gene names: 158423608

Gene position: 2288125-2287175 (Counterclockwise)

Preceding gene: 158423609

Following gene: 158423607

Centisome position: 42.61

GC content: 67.82

Gene sequence:

>951_bases
ATGGCGCTCACCACCGCTTCGCCCGAGCGCACGCCTAACTGGTTCGCCCGCGCCTGGGATTCGGACATCGGTCATTCCTT
CCGCACCTCGCCCGTCACCATGCTGGCAGCCTTCGTGGTGCTGGTGATCGCGCTTGCCGCCCTGTTCGCACCCTGGATCG
CGCCCACCGACCCGTTCGACCCCGCTTCCCTCAACCTGATGGACGGCAAGACCCCGCCGCTGACGCCCAGCGCCTTCACC
GGCAACGAATTTTTGCTGGGCACCGATGACCAGGGGCGCGATGTCTTCTCCGCCATCCTCTATGGGGCGCGGATGTCGCT
GCTGGTGGGGCTCGCCTCGGTGGCGGTGTCCATCGGGCTGGGCGTCGGCCTCGGCCTGCTGGCGGGCTATCGCGGCGGCT
GGCTGGACAGCCTCATCATGCGCGTGGCGGACATCCAGCTCACCTTTCCGGACATCCTCGTCGCCATGCTGATCTTCGGC
GTGGCGCGCGGAGCGGTGCCGGTTACGGCGCAGGAGAGCATCGCCATTCCGGTGCTCATCCTCTCCATCGGCGTGTCGAA
ATGGCCGCAATATGCCCGCACCGTGCGCGGCCTGACGCTGGTGGAGCGGGGCAAGGACTATGTGGCGGCCGCCCGCGTGG
TGGGCCTGCCGCAGGCCACCATCATGCGCCGGCACATTCTGCCCAACGTGATCGGTCCGGTTCTGGTGATCGCCACGCTC
GGCCTATCGCTCGCCATCATCACCGAGGCGACGCTCTCCTTTCTCGGCGTCGGCGCGCCGCCGACCCAGCCCTCGCTGGG
CACGCTGATCCGGATCGGGCAGGAATATATCGCCTCCGGTGAATGGTGGATCCTGTTCTTTCCGGCGGTCACGCTGCTCG
CCATCGCCCTCTCGGTGAACCTGCTGGGCGACTGGCTGCGCGATGCGCTGAACCCGAGGCTGCGCGGATGA

Upstream 100 bases:

>100_bases
CTGCTGTTCGTCGCCGGCTTCTTCGTGGCGGTGAACCTCATCGTCGATCTCCTGTATTTCGCCGTCGATCCGCGCCTGCG
CGGCTCGGGAGGGCACTGAC

Downstream 100 bases:

>100_bases
GCGAGACGCCCCTTCTCTCCGTCAAGGGCCTGCGGGTCGAGTTCCGCACCCGGCGCGGCACGCTCACTGCCGTGGACGAC
GTCTCCTTCGATCTCGCCCC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MALTTASPERTPNWFARAWDSDIGHSFRTSPVTMLAAFVVLVIALAALFAPWIAPTDPFDPASLNLMDGKTPPLTPSAFT
GNEFLLGTDDQGRDVFSAILYGARMSLLVGLASVAVSIGLGVGLGLLAGYRGGWLDSLIMRVADIQLTFPDILVAMLIFG
VARGAVPVTAQESIAIPVLILSIGVSKWPQYARTVRGLTLVERGKDYVAAARVVGLPQATIMRRHILPNVIGPVLVIATL
GLSLAIITEATLSFLGVGAPPTQPSLGTLIRIGQEYIASGEWWILFFPAVTLLAIALSVNLLGDWLRDALNPRLRG

Sequences:

>Translated_316_residues
MALTTASPERTPNWFARAWDSDIGHSFRTSPVTMLAAFVVLVIALAALFAPWIAPTDPFDPASLNLMDGKTPPLTPSAFT
GNEFLLGTDDQGRDVFSAILYGARMSLLVGLASVAVSIGLGVGLGLLAGYRGGWLDSLIMRVADIQLTFPDILVAMLIFG
VARGAVPVTAQESIAIPVLILSIGVSKWPQYARTVRGLTLVERGKDYVAAARVVGLPQATIMRRHILPNVIGPVLVIATL
GLSLAIITEATLSFLGVGAPPTQPSLGTLIRIGQEYIASGEWWILFFPAVTLLAIALSVNLLGDWLRDALNPRLRG
>Mature_315_residues
ALTTASPERTPNWFARAWDSDIGHSFRTSPVTMLAAFVVLVIALAALFAPWIAPTDPFDPASLNLMDGKTPPLTPSAFTG
NEFLLGTDDQGRDVFSAILYGARMSLLVGLASVAVSIGLGVGLGLLAGYRGGWLDSLIMRVADIQLTFPDILVAMLIFGV
ARGAVPVTAQESIAIPVLILSIGVSKWPQYARTVRGLTLVERGKDYVAAARVVGLPQATIMRRHILPNVIGPVLVIATLG
LSLAIITEATLSFLGVGAPPTQPSLGTLIRIGQEYIASGEWWILFFPAVTLLAIALSVNLLGDWLRDALNPRLRG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=318, Percent_Identity=36.1635220125786, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1787760, Length=290, Percent_Identity=35.1724137931034, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1789964, Length=294, Percent_Identity=39.1156462585034, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1789889, Length=261, Percent_Identity=32.5670498084291, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787498, Length=321, Percent_Identity=32.7102803738318, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788505, Length=258, Percent_Identity=32.1705426356589, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787549, Length=304, Percent_Identity=26.9736842105263, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33590; Mature: 33459

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTTASPERTPNWFARAWDSDIGHSFRTSPVTMLAAFVVLVIALAALFAPWIAPTDPFD
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PASLNLMDGKTPPLTPSAFTGNEFLLGTDDQGRDVFSAILYGARMSLLVGLASVAVSIGL
CCCEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGLGLLAGYRGGWLDSLIMRVADIQLTFPDILVAMLIFGVARGAVPVTAQESIAIPVLI
HHHHHHHHCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LSIGVSKWPQYARTVRGLTLVERGKDYVAAARVVGLPQATIMRRHILPNVIGPVLVIATL
HHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLSLAIITEATLSFLGVGAPPTQPSLGTLIRIGQEYIASGEWWILFFPAVTLLAIALSVN
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
LLGDWLRDALNPRLRG
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALTTASPERTPNWFARAWDSDIGHSFRTSPVTMLAAFVVLVIALAALFAPWIAPTDPFD
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PASLNLMDGKTPPLTPSAFTGNEFLLGTDDQGRDVFSAILYGARMSLLVGLASVAVSIGL
CCCEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGLGLLAGYRGGWLDSLIMRVADIQLTFPDILVAMLIFGVARGAVPVTAQESIAIPVLI
HHHHHHHHCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LSIGVSKWPQYARTVRGLTLVERGKDYVAAARVVGLPQATIMRRHILPNVIGPVLVIATL
HHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLSLAIITEATLSFLGVGAPPTQPSLGTLIRIGQEYIASGEWWILFFPAVTLLAIALSVN
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
LLGDWLRDALNPRLRG
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]