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The map label for this gene is 158423562

Identifier: 158423562

GI number: 158423562

Start: 2238697

End: 2239812

Strand: Reverse

Name: 158423562

Synonym: AZC_1938

Alternate gene names: NA

Gene position: 2239812-2238697 (Counterclockwise)

Preceding gene: 158423563

Following gene: 158423558

Centisome position: 41.71

GC content: 66.31

Gene sequence:

>1116_bases
ATGCGGACCTCTGCCGGTAGCGACGTCGAGTATGCTTTTCTCAGAGCACCGGGACAGATGCCGGGGGCGATCCGTGCTTT
CGACTGGTCCACGACCCCGCTCGGCCCGATCTCAAGCTGGCCCGTCTCCTTGCGCAGTGCCGTCGGCCTCATGCTGGCCT
CGCACTTTCCCAAGGCGGTGATCTGGGGCCCGTCGCTGACGACCCTCTATAACGACGCGTTCCTGCCCATCCTCGGCAGC
AAGCCGGCGCCGCTCGGCCGCCCGTTCAACGAGATCTGGAGCGAGGTGTGGCCGCAGGTGGAGGCCATCCAGCAGAAGGC
CTTCGCGGGAGAAGCCACCTTCATCGAGGATTTCCCCCTCGTAATCGAGCGTAACGGGCAGCCCGAGCACGCCTATTTCA
CCTTCTGCTACAGCCCGCTTCTCGATGACGACGGCAACGTCGCCGGCATGCTGGATACGGTCATCGAGACCACCGGCAAG
ATGGCTGCGCTGCGGGACGTCAAGCTCATCAATGGCGAGCTGGAGCACCGCATCCGCAACACGCTGGCCATCGTCGGCGG
CATTGCCCACCAGACCTTCCGCTTCGCGGGTTCGCTGACCGAGGCGCGCGACATGTTCAATGCGCGCCTCGCGGCGCTCG
GCAACGCCCATTCAGCGCTGACGCAGTCCAACTGGGCGAGCACGCCCATCGAACTTCTGCTGCGCAAGAGCCTGTCGCCC
TATCAGTCGGCCGGCAACCAGATCACGCTGGAAGGTCCGGCACTCGACATCCCGCCCCAGAAGGGCCTGACGCTCTCCCT
CGCCATCAACGAACTGGCTGCCAATGCCCTGAAGCACGGCGCCCTGTCCACGCCGGACGGACACGTCAGCGTGCAATGGA
GCGCCGATCATCCGCCGGCGCTCGAGGGGTTCGCCTTGAACTGGATGGAGCGCGGCGGCCCACCGGTGCAGCCGCCGAAC
CGTACCGGGTTCGGTACGTTCCTGCTTCAGGCGCTGGCGGGTGCATTCAATGGCACCGTGGCCGCCGACTATGCGCCCGA
GGGCCTGACCTTCCGCCTCTCCACGCCGCCTGCGGTGATGCCGACGGCCGTGAAGGCCGGGATCAGTTCCCGCTGA

Upstream 100 bases:

>100_bases
TGTGCCTGCCGGCTTCGCCCTTGCGCCTCCGGCCCCAGCGGTGCCATAGCTGTCTTCACAGTGTCCGGGGTGATCTCCCG
CACGCGGGATTGAAGAAACG

Downstream 100 bases:

>100_bases
AGAGCTGGGTGCCCACCTTGTCACCGGTGGCGATGCCCAGCTTGCGGGCTTCCCCGCCGCCGATCTCGATCACCGCCCGC
ACCGGCTCGCCGGAGGAGAT

Product: HWE histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRTSAGSDVEYAFLRAPGQMPGAIRAFDWSTTPLGPISSWPVSLRSAVGLMLASHFPKAVIWGPSLTTLYNDAFLPILGS
KPAPLGRPFNEIWSEVWPQVEAIQQKAFAGEATFIEDFPLVIERNGQPEHAYFTFCYSPLLDDDGNVAGMLDTVIETTGK
MAALRDVKLINGELEHRIRNTLAIVGGIAHQTFRFAGSLTEARDMFNARLAALGNAHSALTQSNWASTPIELLLRKSLSP
YQSAGNQITLEGPALDIPPQKGLTLSLAINELAANALKHGALSTPDGHVSVQWSADHPPALEGFALNWMERGGPPVQPPN
RTGFGTFLLQALAGAFNGTVAADYAPEGLTFRLSTPPAVMPTAVKAGISSR

Sequences:

>Translated_371_residues
MRTSAGSDVEYAFLRAPGQMPGAIRAFDWSTTPLGPISSWPVSLRSAVGLMLASHFPKAVIWGPSLTTLYNDAFLPILGS
KPAPLGRPFNEIWSEVWPQVEAIQQKAFAGEATFIEDFPLVIERNGQPEHAYFTFCYSPLLDDDGNVAGMLDTVIETTGK
MAALRDVKLINGELEHRIRNTLAIVGGIAHQTFRFAGSLTEARDMFNARLAALGNAHSALTQSNWASTPIELLLRKSLSP
YQSAGNQITLEGPALDIPPQKGLTLSLAINELAANALKHGALSTPDGHVSVQWSADHPPALEGFALNWMERGGPPVQPPN
RTGFGTFLLQALAGAFNGTVAADYAPEGLTFRLSTPPAVMPTAVKAGISSR
>Mature_371_residues
MRTSAGSDVEYAFLRAPGQMPGAIRAFDWSTTPLGPISSWPVSLRSAVGLMLASHFPKAVIWGPSLTTLYNDAFLPILGS
KPAPLGRPFNEIWSEVWPQVEAIQQKAFAGEATFIEDFPLVIERNGQPEHAYFTFCYSPLLDDDGNVAGMLDTVIETTGK
MAALRDVKLINGELEHRIRNTLAIVGGIAHQTFRFAGSLTEARDMFNARLAALGNAHSALTQSNWASTPIELLLRKSLSP
YQSAGNQITLEGPALDIPPQKGLTLSLAINELAANALKHGALSTPDGHVSVQWSADHPPALEGFALNWMERGGPPVQPPN
RTGFGTFLLQALAGAFNGTVAADYAPEGLTFRLSTPPAVMPTAVKAGISSR

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39737; Mature: 39737

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSAGSDVEYAFLRAPGQMPGAIRAFDWSTTPLGPISSWPVSLRSAVGLMLASHFPKAV
CCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
IWGPSLTTLYNDAFLPILGSKPAPLGRPFNEIWSEVWPQVEAIQQKAFAGEATFIEDFPL
EECCCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCEEEECCCE
VIERNGQPEHAYFTFCYSPLLDDDGNVAGMLDTVIETTGKMAALRDVKLINGELEHRIRN
EEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TLAIVGGIAHQTFRFAGSLTEARDMFNARLAALGNAHSALTQSNWASTPIELLLRKSLSP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHCCCH
YQSAGNQITLEGPALDIPPQKGLTLSLAINELAANALKHGALSTPDGHVSVQWSADHPPA
HHHCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
LEGFALNWMERGGPPVQPPNRTGFGTFLLQALAGAFNGTVAADYAPEGLTFRLSTPPAVM
CCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCCCCC
PTAVKAGISSR
HHHHHHCCCCC
>Mature Secondary Structure
MRTSAGSDVEYAFLRAPGQMPGAIRAFDWSTTPLGPISSWPVSLRSAVGLMLASHFPKAV
CCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
IWGPSLTTLYNDAFLPILGSKPAPLGRPFNEIWSEVWPQVEAIQQKAFAGEATFIEDFPL
EECCCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCEEEECCCE
VIERNGQPEHAYFTFCYSPLLDDDGNVAGMLDTVIETTGKMAALRDVKLINGELEHRIRN
EEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TLAIVGGIAHQTFRFAGSLTEARDMFNARLAALGNAHSALTQSNWASTPIELLLRKSLSP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHCCCH
YQSAGNQITLEGPALDIPPQKGLTLSLAINELAANALKHGALSTPDGHVSVQWSADHPPA
HHHCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
LEGFALNWMERGGPPVQPPNRTGFGTFLLQALAGAFNGTVAADYAPEGLTFRLSTPPAVM
CCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCCCCC
PTAVKAGISSR
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA