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The map label for this gene is fhuA [H]

Identifier: 158423537

GI number: 158423537

Start: 2193191

End: 2195410

Strand: Reverse

Name: fhuA [H]

Synonym: AZC_1913

Alternate gene names: 158423537

Gene position: 2195410-2193191 (Counterclockwise)

Preceding gene: 158423538

Following gene: 158423536

Centisome position: 40.88

GC content: 64.82

Gene sequence:

>2220_bases
ATGCTTCGCCCTTTCACGCCGCGCGTTTCGCGCGCCGGCATCGCTTTGCTTCTTGCCGGAACCGTCGCTCCCCCCGCCTT
CGCCCAGCAGGCCGCGCCATCGCCGACCCAGAGCGCCGTCGAGCTGCCGACGGTTTCCGTCCAGGCCGTCTCACCGGCGG
AGGAACTGGTGCTGCCGGACATCGCCCGGCTCAACCTCAAGAACGAGACGGGCACGCTGGTCGGCCTGACACCGTTCGAG
ACGCCGGCCGCCATCGACATCGTGACCCAGCAGCAGATGCAGGATCGCGGGCTGCGCACGCTCACGGAGGTCTATAATTC
GGTGCCCGGCGTCATGTCCGGCAATCTGCCCGGCGAGCCCGGCGTCACGTCCATCCGCGGTTTTTCACGCGGCGCGGTCG
GCTACATGCTGGACGGCATGCAGGTGCCCGATCCGCTGATGGTCTCGCGCAATTACGACAGCTTCAGCTTCGACCGGGTC
GAGGTGCTCAAGGGCCCGGCTTCGGTGATCTCCGGCAATGGCGCGCTGGCCGGCACCATCAATCTTGTCACCAAGCAGCC
CATCCTCGGCCAGAACACCGGGCAGGCGCTCCTGAGCTACGGCAGCTTCGATACGCTGCGGGTGGGCGGCGACTACAATG
TCGCCCTCGGCCAGAACGCCGCCGTGCGCGCCAGCGCGCTCTACAGCCAGTCCAACGGCTATATCACCGACACCGGATCC
GAGACGGCCGCCATCACGCTCGGCGCCACCGTCGCCCTGTCGGACCGGCTCACCACCACCACGTCGGTCGATTATTTCCA
CGACGACTACCAGACGCCCTATCAGGGCACGCCGCTCATCGCCCGCTCCGCGGCGCTCTCTCCGTCCAGCGTGGTCTCCG
CGCCCGGCGGCATGGTCATCGACCGGGCATTGTGGAACCGCAACTACAACGTCCTCAACGGCGAGATGAAATCCGATGCG
GTGTGGGCCCGCAACCGCACGGAATACGAACTGACCGACACCTGGACGCTGCGGAACGACCTCAATTATTACACCGCCGA
CCGGCGCTGGGCCAATTCCGAGGACTTCACCTACAACCCGGCCACCCGGTTGCTCGACCGCACCACCACCCTCATCACCC
ACGACCAGCAGGTGTGGTCCGATCAGCTCAGCGCCCGATATGATGGGATGATCGCCAACATGCGCCACCGCTTCGCGATC
GGCGCGGACTACATCCACACGAACTTCGATTCCGAGCGGCGCTTCGGCACCACCACGCCCGTCAATCCCTACTTCCCCAA
CCGGGGCTATTTCCCGGTCGATACATCCGCCAATTTCTCCACCCGGCAGAATTACGACAGCCAGGTGGATCAGGCGGCTG
TCTTCGCCGAGGATGCCATTAACATCACCTCCAACTGGCTGGTGGTGGGCGGTATCCGCTACGAGGCGATCCAGCTCGAC
CGGCAGATCTACAATCTCAATACGCTGTCGACCTCCAGCTTCGGCAACAATTACGAAAGCGTGACCTGGCGGCTCGGCAC
CGTCTACAACATCACGCCCGGCACGGCGCTGTTCGCGCAGTACAATCAGGCCACCGTCCCGGTCACGACGCTGCTGCTGA
GCAACCTGGCCAATGCCAGCTTCGAGCTCTCGACCGGCAATTCCATCGAGGCGGGCATCAAGTCGACCTTCTGGGACAAC
CGGGCGGTGGCGACGGCCTCGGTCTACCAGATCGAGCAATACAACATCCTGACCCGCGACCCCGCCAATCCGTCGCTGAC
CGTCCAGGGCGGCAGCATGCGTTCGCGCGGCGCCGAGGCGGAACTGGCTGTGGCCATCACAGACCAGCTCAAGCTCACGG
CGAATGCGTCCTACATCAATGCCGAATTCACGCAGCTCTGGTCGGCAGGCTCCAATCTCGCCGGCAACCGGCCGCCCAAC
GTGCCCGAATGGACCTACTTCCTGATGGCGGACTACAAGCTGCCGACGCTGCCGATGACGCTGAGCGCATCGGTGCAGTA
CGTCAGTTCCTTCTACACGGACAATGCCAACACCATCGAGGTGGCGGGTCACACCGTGCTGGATGCCTGGGCGAGCTATG
AGATCGGCCGCGGCACCCTGCGGCTGCGCGGGCGCAACCTGACCAACGCCTTCTATGCGGACTGGTCCGGCTACAGCTCC
AGCCAGGTCTTCCTGGGCGCGCCCCGAAGCGTCGAGCTGTCCTACGCCGCCAAGTTCTGA

Upstream 100 bases:

>100_bases
GTCTCTGGTTCGCGAGCGATCCTGCACGCCCATCCGGGCCGCGGACCGCCGTCCGAGCGCGCGGCCGCTCGCCGTCCCCG
CACATCAAGGTGGAAACCCC

Downstream 100 bases:

>100_bases
GCCTCGTATCCCCGGCGGGCGGAGCCACGGCTTCCGCCCGCCCCTTCTGTCCCAATGCGGGAGATGAGCCGTGCGCGACG
CTGTCTGGTCCGCCACCGCT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MLRPFTPRVSRAGIALLLAGTVAPPAFAQQAAPSPTQSAVELPTVSVQAVSPAEELVLPDIARLNLKNETGTLVGLTPFE
TPAAIDIVTQQQMQDRGLRTLTEVYNSVPGVMSGNLPGEPGVTSIRGFSRGAVGYMLDGMQVPDPLMVSRNYDSFSFDRV
EVLKGPASVISGNGALAGTINLVTKQPILGQNTGQALLSYGSFDTLRVGGDYNVALGQNAAVRASALYSQSNGYITDTGS
ETAAITLGATVALSDRLTTTTSVDYFHDDYQTPYQGTPLIARSAALSPSSVVSAPGGMVIDRALWNRNYNVLNGEMKSDA
VWARNRTEYELTDTWTLRNDLNYYTADRRWANSEDFTYNPATRLLDRTTTLITHDQQVWSDQLSARYDGMIANMRHRFAI
GADYIHTNFDSERRFGTTTPVNPYFPNRGYFPVDTSANFSTRQNYDSQVDQAAVFAEDAINITSNWLVVGGIRYEAIQLD
RQIYNLNTLSTSSFGNNYESVTWRLGTVYNITPGTALFAQYNQATVPVTTLLLSNLANASFELSTGNSIEAGIKSTFWDN
RAVATASVYQIEQYNILTRDPANPSLTVQGGSMRSRGAEAELAVAITDQLKLTANASYINAEFTQLWSAGSNLAGNRPPN
VPEWTYFLMADYKLPTLPMTLSASVQYVSSFYTDNANTIEVAGHTVLDAWASYEIGRGTLRLRGRNLTNAFYADWSGYSS
SQVFLGAPRSVELSYAAKF

Sequences:

>Translated_739_residues
MLRPFTPRVSRAGIALLLAGTVAPPAFAQQAAPSPTQSAVELPTVSVQAVSPAEELVLPDIARLNLKNETGTLVGLTPFE
TPAAIDIVTQQQMQDRGLRTLTEVYNSVPGVMSGNLPGEPGVTSIRGFSRGAVGYMLDGMQVPDPLMVSRNYDSFSFDRV
EVLKGPASVISGNGALAGTINLVTKQPILGQNTGQALLSYGSFDTLRVGGDYNVALGQNAAVRASALYSQSNGYITDTGS
ETAAITLGATVALSDRLTTTTSVDYFHDDYQTPYQGTPLIARSAALSPSSVVSAPGGMVIDRALWNRNYNVLNGEMKSDA
VWARNRTEYELTDTWTLRNDLNYYTADRRWANSEDFTYNPATRLLDRTTTLITHDQQVWSDQLSARYDGMIANMRHRFAI
GADYIHTNFDSERRFGTTTPVNPYFPNRGYFPVDTSANFSTRQNYDSQVDQAAVFAEDAINITSNWLVVGGIRYEAIQLD
RQIYNLNTLSTSSFGNNYESVTWRLGTVYNITPGTALFAQYNQATVPVTTLLLSNLANASFELSTGNSIEAGIKSTFWDN
RAVATASVYQIEQYNILTRDPANPSLTVQGGSMRSRGAEAELAVAITDQLKLTANASYINAEFTQLWSAGSNLAGNRPPN
VPEWTYFLMADYKLPTLPMTLSASVQYVSSFYTDNANTIEVAGHTVLDAWASYEIGRGTLRLRGRNLTNAFYADWSGYSS
SQVFLGAPRSVELSYAAKF
>Mature_739_residues
MLRPFTPRVSRAGIALLLAGTVAPPAFAQQAAPSPTQSAVELPTVSVQAVSPAEELVLPDIARLNLKNETGTLVGLTPFE
TPAAIDIVTQQQMQDRGLRTLTEVYNSVPGVMSGNLPGEPGVTSIRGFSRGAVGYMLDGMQVPDPLMVSRNYDSFSFDRV
EVLKGPASVISGNGALAGTINLVTKQPILGQNTGQALLSYGSFDTLRVGGDYNVALGQNAAVRASALYSQSNGYITDTGS
ETAAITLGATVALSDRLTTTTSVDYFHDDYQTPYQGTPLIARSAALSPSSVVSAPGGMVIDRALWNRNYNVLNGEMKSDA
VWARNRTEYELTDTWTLRNDLNYYTADRRWANSEDFTYNPATRLLDRTTTLITHDQQVWSDQLSARYDGMIANMRHRFAI
GADYIHTNFDSERRFGTTTPVNPYFPNRGYFPVDTSANFSTRQNYDSQVDQAAVFAEDAINITSNWLVVGGIRYEAIQLD
RQIYNLNTLSTSSFGNNYESVTWRLGTVYNITPGTALFAQYNQATVPVTTLLLSNLANASFELSTGNSIEAGIKSTFWDN
RAVATASVYQIEQYNILTRDPANPSLTVQGGSMRSRGAEAELAVAITDQLKLTANASYINAEFTQLWSAGSNLAGNRPPN
VPEWTYFLMADYKLPTLPMTLSASVQYVSSFYTDNANTIEVAGHTVLDAWASYEIGRGTLRLRGRNLTNAFYADWSGYSS
SQVFLGAPRSVELSYAAKF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=777, Percent_Identity=23.1660231660232, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1787344, Length=757, Percent_Identity=22.5891677675033, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787024, Length=733, Percent_Identity=22.5102319236016, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788478, Length=119, Percent_Identity=32.7731092436975, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80564; Mature: 80564

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPFTPRVSRAGIALLLAGTVAPPAFAQQAAPSPTQSAVELPTVSVQAVSPAEELVLPD
CCCCCCCCHHHCCEEEEEECCCCCCHHHHHCCCCCCCCCEECCCEEEEECCCHHHHCCCC
IARLNLKNETGTLVGLTPFETPAAIDIVTQQQMQDRGLRTLTEVYNSVPGVMSGNLPGEP
HHEEEECCCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCC
GVTSIRGFSRGAVGYMLDGMQVPDPLMVSRNYDSFSFDRVEVLKGPASVISGNGALAGTI
CCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCCCCHHEECCCCHHHCCCCCCEEEEE
NLVTKQPILGQNTGQALLSYGSFDTLRVGGDYNVALGQNAAVRASALYSQSNGYITDTGS
EEEECCCCCCCCCCHHHHCCCCCCEEEECCCEEEEECCCCEEEEEEEEECCCCEEEECCC
ETAAITLGATVALSDRLTTTTSVDYFHDDYQTPYQGTPLIARSAALSPSSVVSAPGGMVI
CEEEEEEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCEEECCCCCCHHHHCCCCCEEE
DRALWNRNYNVLNGEMKSDAVWARNRTEYELTDTWTLRNDLNYYTADRRWANSEDFTYNP
EHHHHCCCCEEECCCCCCCEEEECCCCEEEEEEEEEEECCCCEEECCCCCCCCCCCEECH
ATRLLDRTTTLITHDQQVWSDQLSARYDGMIANMRHRFAIGADYIHTNFDSERRFGTTTP
HHHHHHHHHEEEECCHHHHHHHHHHHHCCHHHHCHHEEEECCCEEECCCCCCCCCCCCCC
VNPYFPNRGYFPVDTSANFSTRQNYDSQVDQAAVFAEDAINITSNWLVVGGIRYEAIQLD
CCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCEEEEECCEEEEEEEC
RQIYNLNTLSTSSFGNNYESVTWRLGTVYNITPGTALFAQYNQATVPVTTLLLSNLANAS
HHEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCE
FELSTGNSIEAGIKSTFWDNRAVATASVYQIEQYNILTRDPANPSLTVQGGSMRSRGAEA
EEECCCCCCCCCCHHHCCCCCEEEEEEEEEEEEEEEEEECCCCCEEEEECCCCCCCCCCC
ELAVAITDQLKLTANASYINAEFTQLWSAGSNLAGNRPPNVPEWTYFLMADYKLPTLPMT
EEEEEEECCEEEEECCEEECHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEE
LSASVQYVSSFYTDNANTIEVAGHTVLDAWASYEIGRGTLRLRGRNLTNAFYADWSGYSS
HHHHHHHHHHHHCCCCCEEEECCCEEEHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCC
SQVFLGAPRSVELSYAAKF
CEEEEECCCCEEEEEEECC
>Mature Secondary Structure
MLRPFTPRVSRAGIALLLAGTVAPPAFAQQAAPSPTQSAVELPTVSVQAVSPAEELVLPD
CCCCCCCCHHHCCEEEEEECCCCCCHHHHHCCCCCCCCCEECCCEEEEECCCHHHHCCCC
IARLNLKNETGTLVGLTPFETPAAIDIVTQQQMQDRGLRTLTEVYNSVPGVMSGNLPGEP
HHEEEECCCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCC
GVTSIRGFSRGAVGYMLDGMQVPDPLMVSRNYDSFSFDRVEVLKGPASVISGNGALAGTI
CCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCCCCHHEECCCCHHHCCCCCCEEEEE
NLVTKQPILGQNTGQALLSYGSFDTLRVGGDYNVALGQNAAVRASALYSQSNGYITDTGS
EEEECCCCCCCCCCHHHHCCCCCCEEEECCCEEEEECCCCEEEEEEEEECCCCEEEECCC
ETAAITLGATVALSDRLTTTTSVDYFHDDYQTPYQGTPLIARSAALSPSSVVSAPGGMVI
CEEEEEEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCEEECCCCCCHHHHCCCCCEEE
DRALWNRNYNVLNGEMKSDAVWARNRTEYELTDTWTLRNDLNYYTADRRWANSEDFTYNP
EHHHHCCCCEEECCCCCCCEEEECCCCEEEEEEEEEEECCCCEEECCCCCCCCCCCEECH
ATRLLDRTTTLITHDQQVWSDQLSARYDGMIANMRHRFAIGADYIHTNFDSERRFGTTTP
HHHHHHHHHEEEECCHHHHHHHHHHHHCCHHHHCHHEEEECCCEEECCCCCCCCCCCCCC
VNPYFPNRGYFPVDTSANFSTRQNYDSQVDQAAVFAEDAINITSNWLVVGGIRYEAIQLD
CCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCEEEEECCEEEEEEEC
RQIYNLNTLSTSSFGNNYESVTWRLGTVYNITPGTALFAQYNQATVPVTTLLLSNLANAS
HHEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCE
FELSTGNSIEAGIKSTFWDNRAVATASVYQIEQYNILTRDPANPSLTVQGGSMRSRGAEA
EEECCCCCCCCCCHHHCCCCCEEEEEEEEEEEEEEEEEECCCCCEEEEECCCCCCCCCCC
ELAVAITDQLKLTANASYINAEFTQLWSAGSNLAGNRPPNVPEWTYFLMADYKLPTLPMT
EEEEEEECCEEEEECCEEECHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEE
LSASVQYVSSFYTDNANTIEVAGHTVLDAWASYEIGRGTLRLRGRNLTNAFYADWSGYSS
HHHHHHHHHHHHCCCCCEEEECCCEEEHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCC
SQVFLGAPRSVELSYAAKF
CEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]