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The map label for this gene is rnr [H]

Identifier: 158423483

GI number: 158423483

Start: 2124572

End: 2127016

Strand: Reverse

Name: rnr [H]

Synonym: AZC_1859

Alternate gene names: 158423483

Gene position: 2127016-2124572 (Counterclockwise)

Preceding gene: 158423485

Following gene: 158423482

Centisome position: 39.61

GC content: 69.24

Gene sequence:

>2445_bases
TTGTCAGGCCGCCCGGCGCAACTGGATTTTTGCCCGTGCCACTGCGGGCCACGGGACACGCCCTTGCCCAAACGACCCTC
GACGCCGAAACGCCCTGCCCCCAGCCGCAAGACCCGCGCCGTGCGCCAGCCGGACGCCCCCGCCTTCAAGGCCACCGGCG
TCCTGCCCGGCAAGGAGGAGGTGCTGGCCTTCATCGCCTCGCAGGGTGGCAAGGTGAGCAAGCGCGACATCGCCCGTGCC
TTCGGCCTCGGCTCCGGCCAGAAGATCGAATTGAAGGCGTTGCTGCGCGACCTCAAGGACGAGGGCGCCGTGGAAGGCGG
CCGGCGCCGCATGCATGTTCCCGGCAGCCTCCCGAGCGTGGTGCTGGTGGATGTGACCGGTCGCGATGGCGACGGCGAAC
TGCTGGCCGTGCCGACGGAATGGGACAGCGAGGAACACGGCGATGCGCCGGTGATCCTGCTGCACGTCCCGGACAAGCTG
CGTGGCCCCGCCCCCGGCCTCTCGGACCGCATTGTGGTGCGGGTGGAGCCGAACGATCCCGCGCCCGGCATCGGCTATAC
CGGCCGCGTCATCAAGGTGCTGGAGAAAGCCCGCAAGCAGCAGCTCGGGGTCTTCCGAAAGGCGCCTCCCGGCAGCAGCG
GTGGCGGGCGCATCATCCCCATCGACAAGAAGAACCTCGGCCGCGAGCTTCAGGTGCCGCCCGGTGCCGAGAATGGCGCG
GAGGACGGCGACCTCGTCTCGGTGGAGATGATGCACCAGCGCGTCTTCGGCCAGCCCACCGCGCGGGTGAAGGAGCGCCT
CGGCTCGCTCGCCACAGAGAAGGCCATCAGCCTCGTCGCCATCCACGCCCACGGCATTCCCAACGCCTTCCCGGCCAAGG
TGATCGCCGAGGCCGAGGCCGCAAGGCCCGCGACCGCCAAGGGCCGCGAAGACTGGCGCAAGCTGCCCCTCGTCACCATC
GATCCGCCCGACGCCAAGGACCATGACGACGCCGTCCATGCGGTGCCGGACGACGACCCGGACAATGCGGGCGGCTTCAT
CGTCACGGTCGCCATCGCGGACGTCGCCGCCTATGTGCGGCCGGGCTCGGCTCTGGACCGCGAGGCATTGCTGCGCGGCA
ATTCGGTCTATTTCCCGGACCGGGTGGTGCCCATGCTGCCCGAGCGCATCTCCAACGATCTGTGCTCGCTACGCCCGCAG
GAGGACCGTGCCGCGCTTGCCGTCCGAATGGTCATCGGCAAGGACGGGCGCAAGCGCAGCCACTCCTTCCACCGCATCCT
CATGCGCTCGGCAGCCAAGCTCGCCTATGAGCAGGCGCAGGCCGCCATCGACGGGGTGAGCGACGACACCACCGCGCCGC
TGCTGGAAAGCGTCCTGCGCCCGCTTTATGCCGCCTATGCCTGCGTGAAGCAGGCGCGCGACGCCCGCCAACCGCTGGAA
CTGGACCTGCCCGAGCGCAAGATCCTCCTGAAGGAGGACGGCACGGTGGACCGGGTGATCGTCCCGCCCCGGCTCGACGC
CCACCGCCTCATCGAGGAATTCATGATCCTCGCCAATGTGGCTGCCGCCGAGACGCTCGAGCAGAAGAAGGTGCCGCTCA
TCTTCCGCGTCCATGACGGGCCGACGCTCGCCAAGCTGTCGGCCCTGCGGGAGTTTCTGGCGACGCTCGACATCTCCCTG
CCGAAGACCGACCAGGTGCGCCCCTCCCACTTCAACCGCATCCTCGGCATGGTGGACGGCGGCGACAGCGCCCCCCTCGT
CAATCAGGTGATCCTGCGCAGCCAGTCGCAGGCGGAATATTCCTCGGAGAATTACGGTCACTTCGGCCTCAACCTGCGCC
GCTACGCCCATTTCACCTCGCCCATCCGCCGCTATGCGGACCTCGTGGTGCATCGCGGCCTGCTGCGAACGCTGGGTGCA
GATGCCGATGCCTTGCCCGAGACCGCGACCGTCGAGACGCTGGCGGAAATCTCTGCCGACATCTCAGCCACCGAGCGCCG
GGCCATGGCGGCGGAGCGCGAGACGGTGGACCGGCTGATCGCCCATCATCTCGCCGAGCAGATCGGCGCCGTCTTCCAGG
GCCGCATCACCGGGGCGACCCGCGCCGGCCTGTTCGTGGCGCTCGACGAGACGGGCGCGGACGGCTTCGTGCCCGCCGCC
AGCCTCGGCCAGGACTATTACCGCTTCGACGAGACCCGGCAGGCCCTGGTGGGTGATCGCACCGGCGAAATGCACCGTAT
CGGGGACCGGGTGGAGGTGAAGCTGGTGGAAGCGGCTCCCGTAGCGGGAGCCTTGCGGTTTGAACTTCTGTCGGAAGGCT
CCTATTTGGGGAGGGGCAAGTCCGCCAAGGGACGGGGGGCCGAACGGCCCGCCTCCAAGGCCGCGAAGGCGCGGGCCGGT
TTTGCCAAGCGCACCGCCGGGCGCGCGCCACGCAAGGGACGATAG

Upstream 100 bases:

>100_bases
CCGCGGCGGCTGCCTTCCACAAATCGTGGAATGACTTTGAAATCAGGGGCCCGCTGCACTAGCCTGCGGCCCGTGCCGGG
GCCTCGCGCGCCTCACGGGG

Downstream 100 bases:

>100_bases
GCACGCATGACGCAGACCATGAATGCAGAACGGGACGCTGCCAGCGCCATGATGCGCGGCGCCCGTGGCCTCTGTCCCGC
CTGCGGCGTCGGCAAGCTGT

Product: 3'-5' exoribonuclease

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 814; Mature: 813

Protein sequence:

>814_residues
MSGRPAQLDFCPCHCGPRDTPLPKRPSTPKRPAPSRKTRAVRQPDAPAFKATGVLPGKEEVLAFIASQGGKVSKRDIARA
FGLGSGQKIELKALLRDLKDEGAVEGGRRRMHVPGSLPSVVLVDVTGRDGDGELLAVPTEWDSEEHGDAPVILLHVPDKL
RGPAPGLSDRIVVRVEPNDPAPGIGYTGRVIKVLEKARKQQLGVFRKAPPGSSGGGRIIPIDKKNLGRELQVPPGAENGA
EDGDLVSVEMMHQRVFGQPTARVKERLGSLATEKAISLVAIHAHGIPNAFPAKVIAEAEAARPATAKGREDWRKLPLVTI
DPPDAKDHDDAVHAVPDDDPDNAGGFIVTVAIADVAAYVRPGSALDREALLRGNSVYFPDRVVPMLPERISNDLCSLRPQ
EDRAALAVRMVIGKDGRKRSHSFHRILMRSAAKLAYEQAQAAIDGVSDDTTAPLLESVLRPLYAAYACVKQARDARQPLE
LDLPERKILLKEDGTVDRVIVPPRLDAHRLIEEFMILANVAAAETLEQKKVPLIFRVHDGPTLAKLSALREFLATLDISL
PKTDQVRPSHFNRILGMVDGGDSAPLVNQVILRSQSQAEYSSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRTLGA
DADALPETATVETLAEISADISATERRAMAAERETVDRLIAHHLAEQIGAVFQGRITGATRAGLFVALDETGADGFVPAA
SLGQDYYRFDETRQALVGDRTGEMHRIGDRVEVKLVEAAPVAGALRFELLSEGSYLGRGKSAKGRGAERPASKAAKARAG
FAKRTAGRAPRKGR

Sequences:

>Translated_814_residues
MSGRPAQLDFCPCHCGPRDTPLPKRPSTPKRPAPSRKTRAVRQPDAPAFKATGVLPGKEEVLAFIASQGGKVSKRDIARA
FGLGSGQKIELKALLRDLKDEGAVEGGRRRMHVPGSLPSVVLVDVTGRDGDGELLAVPTEWDSEEHGDAPVILLHVPDKL
RGPAPGLSDRIVVRVEPNDPAPGIGYTGRVIKVLEKARKQQLGVFRKAPPGSSGGGRIIPIDKKNLGRELQVPPGAENGA
EDGDLVSVEMMHQRVFGQPTARVKERLGSLATEKAISLVAIHAHGIPNAFPAKVIAEAEAARPATAKGREDWRKLPLVTI
DPPDAKDHDDAVHAVPDDDPDNAGGFIVTVAIADVAAYVRPGSALDREALLRGNSVYFPDRVVPMLPERISNDLCSLRPQ
EDRAALAVRMVIGKDGRKRSHSFHRILMRSAAKLAYEQAQAAIDGVSDDTTAPLLESVLRPLYAAYACVKQARDARQPLE
LDLPERKILLKEDGTVDRVIVPPRLDAHRLIEEFMILANVAAAETLEQKKVPLIFRVHDGPTLAKLSALREFLATLDISL
PKTDQVRPSHFNRILGMVDGGDSAPLVNQVILRSQSQAEYSSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRTLGA
DADALPETATVETLAEISADISATERRAMAAERETVDRLIAHHLAEQIGAVFQGRITGATRAGLFVALDETGADGFVPAA
SLGQDYYRFDETRQALVGDRTGEMHRIGDRVEVKLVEAAPVAGALRFELLSEGSYLGRGKSAKGRGAERPASKAAKARAG
FAKRTAGRAPRKGR
>Mature_813_residues
SGRPAQLDFCPCHCGPRDTPLPKRPSTPKRPAPSRKTRAVRQPDAPAFKATGVLPGKEEVLAFIASQGGKVSKRDIARAF
GLGSGQKIELKALLRDLKDEGAVEGGRRRMHVPGSLPSVVLVDVTGRDGDGELLAVPTEWDSEEHGDAPVILLHVPDKLR
GPAPGLSDRIVVRVEPNDPAPGIGYTGRVIKVLEKARKQQLGVFRKAPPGSSGGGRIIPIDKKNLGRELQVPPGAENGAE
DGDLVSVEMMHQRVFGQPTARVKERLGSLATEKAISLVAIHAHGIPNAFPAKVIAEAEAARPATAKGREDWRKLPLVTID
PPDAKDHDDAVHAVPDDDPDNAGGFIVTVAIADVAAYVRPGSALDREALLRGNSVYFPDRVVPMLPERISNDLCSLRPQE
DRAALAVRMVIGKDGRKRSHSFHRILMRSAAKLAYEQAQAAIDGVSDDTTAPLLESVLRPLYAAYACVKQARDARQPLEL
DLPERKILLKEDGTVDRVIVPPRLDAHRLIEEFMILANVAAAETLEQKKVPLIFRVHDGPTLAKLSALREFLATLDISLP
KTDQVRPSHFNRILGMVDGGDSAPLVNQVILRSQSQAEYSSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRTLGAD
ADALPETATVETLAEISADISATERRAMAAERETVDRLIAHHLAEQIGAVFQGRITGATRAGLFVALDETGADGFVPAAS
LGQDYYRFDETRQALVGDRTGEMHRIGDRVEVKLVEAAPVAGALRFELLSEGSYLGRGKSAKGRGAERPASKAAKARAGF
AKRTAGRAPRKGR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=510, Percent_Identity=27.6470588235294, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI190014623, Length=510, Percent_Identity=27.6470588235294, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI134288890, Length=364, Percent_Identity=34.0659340659341, Blast_Score=160, Evalue=7e-39,
Organism=Homo sapiens, GI19115966, Length=631, Percent_Identity=27.0998415213946, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI219521928, Length=631, Percent_Identity=27.0998415213946, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI156105693, Length=546, Percent_Identity=27.4725274725275, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI156105695, Length=548, Percent_Identity=27.007299270073, Blast_Score=87, Evalue=8e-17,
Organism=Escherichia coli, GI87082383, Length=746, Percent_Identity=34.5844504021448, Blast_Score=374, Evalue=1e-104,
Organism=Escherichia coli, GI1787542, Length=422, Percent_Identity=33.6492890995261, Blast_Score=176, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI212645896, Length=487, Percent_Identity=31.211498973306, Blast_Score=178, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17553506, Length=380, Percent_Identity=32.3684210526316, Blast_Score=162, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=499, Percent_Identity=30.6613226452906, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6320499, Length=383, Percent_Identity=24.2819843342037, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649634, Length=481, Percent_Identity=27.8586278586279, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19922976, Length=358, Percent_Identity=29.3296089385475, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24654597, Length=358, Percent_Identity=29.3296089385475, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24654592, Length=358, Percent_Identity=29.3296089385475, Blast_Score=123, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 87977; Mature: 87845

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II ; PS00200 RIESKE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRPAQLDFCPCHCGPRDTPLPKRPSTPKRPAPSRKTRAVRQPDAPAFKATGVLPGKEE
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCHHH
VLAFIASQGGKVSKRDIARAFGLGSGQKIELKALLRDLKDEGAVEGGRRRMHVPGSLPSV
HHHHHHHCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECCCCCCCE
VLVDVTGRDGDGELLAVPTEWDSEEHGDAPVILLHVPDKLRGPAPGLSDRIVVRVEPNDP
EEEEEECCCCCCCEEEECCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCEEEEEECCCCC
APGIGYTGRVIKVLEKARKQQLGVFRKAPPGSSGGGRIIPIDKKNLGRELQVPPGAENGA
CCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEEEECHHHCCCEEECCCCCCCCC
EDGDLVSVEMMHQRVFGQPTARVKERLGSLATEKAISLVAIHAHGIPNAFPAKVIAEAEA
CCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHH
ARPATAKGREDWRKLPLVTIDPPDAKDHDDAVHAVPDDDPDNAGGFIVTVAIADVAAYVR
CCCCCCCCHHHHHHCCEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEEEHHHHHHHHHC
PGSALDREALLRGNSVYFPDRVVPMLPERISNDLCSLRPQEDRAALAVRMVIGKDGRKRS
CCCCCCHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHCCCCCHHH
HSFHRILMRSAAKLAYEQAQAAIDGVSDDTTAPLLESVLRPLYAAYACVKQARDARQPLE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LDLPERKILLKEDGTVDRVIVPPRLDAHRLIEEFMILANVAAAETLEQKKVPLIFRVHDG
CCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PTLAKLSALREFLATLDISLPKTDQVRPSHFNRILGMVDGGDSAPLVNQVILRSQSQAEY
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHCCHHHHH
SSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRTLGADADALPETATVETLAEISAD
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
ISATERRAMAAERETVDRLIAHHLAEQIGAVFQGRITGATRAGLFVALDETGADGFVPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHH
SLGQDYYRFDETRQALVGDRTGEMHRIGDRVEVKLVEAAPVAGALRFELLSEGSYLGRGK
HHCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCC
SAKGRGAERPASKAAKARAGFAKRTAGRAPRKGR
CCCCCCCCCCHHHHHHHHHCHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGRPAQLDFCPCHCGPRDTPLPKRPSTPKRPAPSRKTRAVRQPDAPAFKATGVLPGKEE
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCHHH
VLAFIASQGGKVSKRDIARAFGLGSGQKIELKALLRDLKDEGAVEGGRRRMHVPGSLPSV
HHHHHHHCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECCCCCCCE
VLVDVTGRDGDGELLAVPTEWDSEEHGDAPVILLHVPDKLRGPAPGLSDRIVVRVEPNDP
EEEEEECCCCCCCEEEECCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCEEEEEECCCCC
APGIGYTGRVIKVLEKARKQQLGVFRKAPPGSSGGGRIIPIDKKNLGRELQVPPGAENGA
CCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEEEECHHHCCCEEECCCCCCCCC
EDGDLVSVEMMHQRVFGQPTARVKERLGSLATEKAISLVAIHAHGIPNAFPAKVIAEAEA
CCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHH
ARPATAKGREDWRKLPLVTIDPPDAKDHDDAVHAVPDDDPDNAGGFIVTVAIADVAAYVR
CCCCCCCCHHHHHHCCEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEEEHHHHHHHHHC
PGSALDREALLRGNSVYFPDRVVPMLPERISNDLCSLRPQEDRAALAVRMVIGKDGRKRS
CCCCCCHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHCCCCCHHH
HSFHRILMRSAAKLAYEQAQAAIDGVSDDTTAPLLESVLRPLYAAYACVKQARDARQPLE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LDLPERKILLKEDGTVDRVIVPPRLDAHRLIEEFMILANVAAAETLEQKKVPLIFRVHDG
CCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PTLAKLSALREFLATLDISLPKTDQVRPSHFNRILGMVDGGDSAPLVNQVILRSQSQAEY
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHCCHHHHH
SSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRTLGADADALPETATVETLAEISAD
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
ISATERRAMAAERETVDRLIAHHLAEQIGAVFQGRITGATRAGLFVALDETGADGFVPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHH
SLGQDYYRFDETRQALVGDRTGEMHRIGDRVEVKLVEAAPVAGALRFELLSEGSYLGRGK
HHCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCC
SAKGRGAERPASKAAKARAGFAKRTAGRAPRKGR
CCCCCCCCCCHHHHHHHHHCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]