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The map label for this gene is topA [H]

Identifier: 158423485

GI number: 158423485

Start: 2128797

End: 2131475

Strand: Reverse

Name: topA [H]

Synonym: AZC_1861

Alternate gene names: 158423485

Gene position: 2131475-2128797 (Counterclockwise)

Preceding gene: 158423486

Following gene: 158423483

Centisome position: 39.69

GC content: 68.46

Gene sequence:

>2679_bases
ATGCAGGTCGTCATCGTCGAATCGCCGGCTAAGGCGAAGACGATCAACAAATATCTCGGACCAGGCTACGAGGTCATCGC
GTCCTACGGGCACATCCGCGACCTTCCCTCCAAGGATGGATCGGTGGACCCGGAAGCGGACTTCCGGATGCTCTGGGAGG
TTGATCCCAAGGCCCAGAAGCGGCTCAACGACATTGCCAAGGCGGTCAAGGTGGCTGACGGCCTGATCCTCGCCACCGAC
CCGGATCGCGAAGGCGAGGCCATTTCCTGGCACGTGCTGGAAGTGCTGCGGGAGAAGAAGGCGCTGAAGGGCCAGAAGGT
CGAGCGCGTCGTCTTCAACGCCATCACCAAGCAGGCCGTGCTGGAGGCCATGAAGGCCCCGCGCGCCGTGGACGTGGCGC
TGGTGGACGCCTATCTCGCGCGCCGCGCGCTGGACTATCTCGTCGGCTTCACCCTTTCTCCCGTGCTGTGGCGCAAGCTG
CCCGGCGCCCGCTCCGCCGGCCGCGTGCAGTCGGTGGCGCTGCGCCTCGTCTGCGACCGCGAGCGCGAGATCGAGCTGTT
CGTCGCCAAGGAATACTGGTCGATCGCCGCGACGCTGGCGACGCCGCGCGGCGACACCTTCGAAGCCCGCCTGTCCGGGG
CCGACGGCAAGAAGATCACCCGCCTCTCGGTGGGCACGGCCGAGGAGGCCGCCGCCTTCCGCGCGGCCCTCGACACGGCG
GCCTTCAGCGTGCGCAACGTGGAAGCCAAGCCCGTGCGGCGCCATCCGCAGCCGCCGTTCACCACCTCGACGCTCCAGCA
GGAGGCGAGCCGCAAGCTCGGCCTTGCGCCGGCCCGCACCATGCAGATCGCCCAGCGCCTCTACGAGGGCGTGGACATCG
GCGGCGAAACGGCCGGTCTCATCACCTATATGCGAACCGACGGCGTGGACATGGCGCCGGAGGCCGTGACTGCCACGCGC
AATGCCATCTCGGCGCAGTACGGCGCCCGCTACCTGCCCGGAACGCCGCGCAAATACACCACCAAGGCGAAGAATGCGCA
GGAGGCCCACGAGGCCATCCGTCCGACCGACCCTTCGCGCCATCCGCGCGAAATGGCCCGCCATCTCGATGCGGAACAGG
CCCGGCTCTACGAGCTGATCTGGACCCGCACGATCGCGAGCCAGATGGAATCGGCCGAGCTCGAACGCACCACCGCCGAC
ATCATCGCCAAGGCCGCCGGCCGCGAGCTGGAGCTGACCGCCACCGGCACGGTGGTGAAGTTCGACGGCTTCCTGACCCT
CTATCGCGAGGGCAAGGACGACGAGGACGATGACGAGGAGAGCCGCCGCCTGCCCGCCATGAGCGCCGGCGAAGCCCTCG
ACAAGCGCGAGATCAAGACCGACCAGCACTTCACCGAACCGCCGCCGCGCTATTCGGAAGCCTCGCTCGTCAAGCGCATG
GAGGAGCTCGGCATCGGCCGCCCCTCCACCTATGCCGCCGTGCTCGCGGTGCTGCGCGACCGCGAATATGTGAAGCTGGA
AAAGAAGCGCCTCGTTCCCGAGGACAAGGGCCGGCTCGTCACCGCCTTCCTCCAGAGCTTCTTCAAGAAGTATGTGGAGT
ACGACTTCACCGCCGACCTCGAGGAGAAGCTCGACGAGATCTCCGCCGCCGAGATCGACTGGAAGCAGGTGCTGCGCGAC
TTCTGGAACGACTTCTCCTTGGCGGTGGACGCCACCAAGGAGCTGCGCGTCTCGCAGGTGATCGACGCCCTCGACGAGAT
CCTGACCGCGCACCTCTTCCCGGCGAAGGAAGACGGCAGCGATCCGCGCCTGTGCCCGACCTGCGGCAGCGGCCGCCTGT
CGCTCAAGATGGGTAAGTTCGGCGCTTTCATCGGCTGCTCGAACTATCCCGAATGCCGCTACACCCGCCCGCTCTCGGGC
GGCGAGGGCGAAGCGGGCGGCGACGGCGTGCGCAAGCTCGGCACCGATCCCGAGACCGGCCTCGAAGTCACTCTGCGAGA
CGGCCGTTTCGGCGCCTATCTCCAGCTCGGCGAGGCGGTGGACGGCGAGAAGCCCAAGCGCTCCAGCCTGCCCAAGGGCC
TTGCTCCGGCGGACGTGGACCTGGAGACGGCGCTCGCGCTGCTGGCCCTGCCCCGCCGCGTCGGCACCCATCCGGAAGAT
GGCGAACCCATCCTCGCCGGCATTGGCCGCTTCGGCCCCTATATCCAGCACGGCAAGGTCTACGCCAATCTGGAAGCGGC
GGACGACGTGCTCACCGTCGGCCTGAACCGGGCCGTGGTGCTGTTGGCGGAGAAGCAGTCCCGCGGCCGCGGCGGTCGCG
GCGCGGCGCCGGCCGGGCGCACGCTGGGCGATCACCCCACCGAAGGCGGGGCGATCACGGTGCGCGCGGGCCGCTTCGGG
CCTTACGTGAACCACGGCAAGATCAACGCCACGCTGCCGAAGTCGCAGGATCCAGACAGCCTGACGCTGGAACAGGCTCT
CGCCCTGATCGAAGCCAAGGCCGCCGCCTCCCCGAGCGCCCGCAAGCCGGCACGCAAGAGCGCGTCCGCCGACGGCGCTG
CGAAGAAGGCCCCGGCCAAAAAGACTGCGACCAAGACCGCCGCCAAGAAGACCACCACCAAGGCTGCGGGGACGAAGAAG
ACCGCCAAGGCCAAGGCGGACGCCGCGGCCGAGGAGTGA

Upstream 100 bases:

>100_bases
GCCTGCCACGGGGGACGGGGGGATTTGACAGCCCAGCCATCGCCCCCCATGTTGCGACCGCCGCCAGGGGCCGCGGCGTT
TCTCAAGAGATTGTTGTCCA

Downstream 100 bases:

>100_bases
CGGGACAGGGCGTCGGCGCTATTCGCCGACGCCGACCACCCCGCCTTCTTCGGAGGTCTTTCGGACGCTCGTGCGCAACG
GCTTCTGCTCCATGCTCATC

Product: DNA topoisomerase I

Products: NA

Alternate protein names: DNA topoisomerase I; Omega-protein; Relaxing enzyme; Swivelase; Untwisting enzyme [H]

Number of amino acids: Translated: 892; Mature: 892

Protein sequence:

>892_residues
MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQKRLNDIAKAVKVADGLILATD
PDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAVLEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKL
PGARSAGRVQSVALRLVCDREREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTA
AFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGLITYMRTDGVDMAPEAVTATR
NAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSRHPREMARHLDAEQARLYELIWTRTIASQMESAELERTTAD
IIAKAAGRELELTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRM
EELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADLEEKLDEISAAEIDWKQVLRD
FWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGSDPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSG
GEGEAGGDGVRKLGTDPETGLEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPED
GEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGRTLGDHPTEGGAITVRAGRFG
PYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSARKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKK
TAKAKADAAAEE

Sequences:

>Translated_892_residues
MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQKRLNDIAKAVKVADGLILATD
PDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAVLEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKL
PGARSAGRVQSVALRLVCDREREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTA
AFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGLITYMRTDGVDMAPEAVTATR
NAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSRHPREMARHLDAEQARLYELIWTRTIASQMESAELERTTAD
IIAKAAGRELELTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRM
EELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADLEEKLDEISAAEIDWKQVLRD
FWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGSDPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSG
GEGEAGGDGVRKLGTDPETGLEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPED
GEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGRTLGDHPTEGGAITVRAGRFG
PYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSARKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKK
TAKAKADAAAEE
>Mature_892_residues
MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQKRLNDIAKAVKVADGLILATD
PDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAVLEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKL
PGARSAGRVQSVALRLVCDREREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTA
AFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGLITYMRTDGVDMAPEAVTATR
NAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSRHPREMARHLDAEQARLYELIWTRTIASQMESAELERTTAD
IIAKAAGRELELTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRM
EELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADLEEKLDEISAAEIDWKQVLRD
FWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGSDPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSG
GEGEAGGDGVRKLGTDPETGLEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPED
GEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGRTLGDHPTEGGAITVRAGRFG
PYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSARKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKK
TAKAKADAAAEE

Specific function: The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another [H]

COG id: COG0550

COG function: function code L; Topoisomerase IA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Homo sapiens, GI10835218, Length=615, Percent_Identity=25.8536585365854, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI4507635, Length=654, Percent_Identity=26.1467889908257, Blast_Score=105, Evalue=2e-22,
Organism=Escherichia coli, GI1787529, Length=666, Percent_Identity=39.6396396396396, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1788061, Length=644, Percent_Identity=25.6211180124224, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32563869, Length=571, Percent_Identity=24.6935201401051, Blast_Score=112, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17555378, Length=473, Percent_Identity=25.5813953488372, Blast_Score=110, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323263, Length=505, Percent_Identity=25.5445544554455, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24585251, Length=598, Percent_Identity=26.4214046822742, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24640096, Length=583, Percent_Identity=24.1852487135506, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013825
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR013498
- InterPro:   IPR005733
- InterPro:   IPR006171 [H]

Pfam domain/function: PF01131 Topoisom_bac; PF01751 Toprim; PF01396 zf-C4_Topoisom [H]

EC number: =5.99.1.2 [H]

Molecular weight: Translated: 96989; Mature: 96989

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00396 TOPOISOMERASE_I_PROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQK
CEEEEECCCCHHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCCCCCCCEEEEEECCHHHHH
RLNDIAKAVKVADGLILATDPDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAV
HHHHHHHHHHHHCCEEEEECCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
EREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTA
CCCEEEEEEHHHHHEEHEEECCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHH
AFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGL
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCE
ITYMRTDGVDMAPEAVTATRNAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSR
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC
HPREMARHLDAEQARLYELIWTRTIASQMESAELERTTADIIAKAAGRELELTATGTVVK
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEE
FDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRM
ECCEEEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
EELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADL
HHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
EEKLDEISAAEIDWKQVLRDFWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGS
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSGGEGEAGGDGVRKLGTDPETG
CCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCEECCCCCCCCCCCCCHHHHCCCCCCCC
LEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPED
CEEEEECCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
GEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGR
CCHHHHHHHHHCCHHHCCEEEEECCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCC
TLGDHPTEGGAITVRAGRFGPYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSA
CCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCC
RKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKKTAKAKADAAAEE
CCCCHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQK
CEEEEECCCCHHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCCCCCCCEEEEEECCHHHHH
RLNDIAKAVKVADGLILATDPDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAV
HHHHHHHHHHHHCCEEEEECCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
EREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTA
CCCEEEEEEHHHHHEEHEEECCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHH
AFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGL
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCE
ITYMRTDGVDMAPEAVTATRNAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSR
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC
HPREMARHLDAEQARLYELIWTRTIASQMESAELERTTADIIAKAAGRELELTATGTVVK
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEE
FDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRM
ECCEEEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
EELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADL
HHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
EEKLDEISAAEIDWKQVLRDFWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGS
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSGGEGEAGGDGVRKLGTDPETG
CCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCEECCCCCCCCCCCCCHHHHCCCCCCCC
LEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPED
CEEEEECCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
GEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGR
CCHHHHHHHHHCCHHHCCEEEEECCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCC
TLGDHPTEGGAITVRAGRFGPYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSA
CCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCC
RKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKKTAKAKADAAAEE
CCCCHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA