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The map label for this gene is 158423421

Identifier: 158423421

GI number: 158423421

Start: 2057348

End: 2059396

Strand: Reverse

Name: 158423421

Synonym: AZC_1797

Alternate gene names: NA

Gene position: 2059396-2057348 (Counterclockwise)

Preceding gene: 158423422

Following gene: 158423420

Centisome position: 38.35

GC content: 70.57

Gene sequence:

>2049_bases
ATGACCTCCCAGGCCCCCATCCGCATCGCCGTCGACATCGGCGGCACCTTCACCGACATCGAGATTCTCGACGCCTCGAC
GGGTGAGATCCACCAGATGAAGACGCCGAGCACGCCCTCGGATCCGTCCATCGGTCTCCTCACCGGCATCAAGGAAGCGA
GTGCCCGCTTCGGCTTTTCGCTGGATCAGGTGCAGTACCTGCTGCACGGCACCACCATCGCCACCAACGCGGTGCTGGAG
CGCAAGCTGCCTCTCGGCGCAGTGGTGACGACGGCCGGCTTCGAGGACGTGATGCAGATCGGCCGGCACGGCCGCACCGA
CGTCTATGCCATCACCGCCTCGCCCCCGGCGCCGCTGGTGAAGCGCCGCCTGTGCTTCGGCGTCTCCGAGCGCATCGGCG
CGGACGGGCGCGTGCTGAAGCCGCTGGACGACCGCTCCGTCGCCTTCCTCGCCGGCAAGCTGCGCGAGGCGGAGGTGAAG
TCGGTCGCCATCTGCTTCCTGCACGCTTATGCCAACCCGGCCCATGAGCGCCGGGCCGGAGAAATCCTGCGCGAACTGCT
GCCGGGCGTCGCCATCACCCTCTCCAGCGATATTTCGCCGGAGCTGCGGGAATATGAGCGCATGTCCACCACCGTGCTCA
ACGCCATGCTGGTGCCCGTGGTGCAGACCTATACGGACCGCCTCGCGGGCAAACTCAAGGAAGAGGTGCCCTCCACGCAG
GTCTATCTCGTGCAGTCGAACGGCGGCGTCTCCGGCCTCGCCAAGGCCGGGCGCGAGCCCGCCCGGCTGCTGCTCTCCGG
CCCCTCGGGCGGGGCGGCGGCGGCCAAGCGCCTCGCGGCCGACCTCGACGAGCCGAACCTCGTCGCGGTGGACATGGGCG
GCACCAGCTTCGACGTCTCCGTGGTGCATGAAGGGGCCGTCGCCATGGTCAATGAGGGCGAGGTGGATGGCCTGCCCGTC
CGCCTGCCCATGATCGAGATGCGCACCATCGGCGCGGGCGGCGGCTCCATCGCCTGGGTGGATGACGGCGGACGCCTGCG
CATCGGTCCGCACAGCGCAGGCGCCGAACCCGGCCCGGCCTGCTACGGGCGCGGCGGCCAGCAGCTCACCGTGACGGATG
CCAACCTGTTGCTGGGCCGGCTGGACGGCTCCAGCTTCATGGGCGGCAAGATGGGCCTCGACCGGGACGCCGCCGCCAAG
GCCGCCGAGGCGGTTTCCGCCAAGCTCGGCCTCTCGCCGGAGGAGACGGCGGCAGGCGTCATCGCCGTCACCAATTCGAG
CCTGGCCACCGCCACCCGCCTCTCGCTGTTCGAGAAGGGCATGGACCCGGAGGACTTCGCCCTCCTGTCCTTCGGCGGCG
CCGGCGGCGTGCACGCCTGCGAGGTGGCCGAGGAACTCGGGATGCGCAAGGTGATCTTCCCCGCCCACGCCTCCACGCTG
TCCGCCTGGGGCATCCTGTGGTCGGACATCACCCACGACCTCTCCGCCACGCAGATCGGCTTGTTCTCCGATCTCGCCCC
CTCCATGGCCCAGAAGGCGCAGGCGCTCGCCGCCGAAGCCAACCGCCTCCTGGCGGAAGACGGCGTGCGACCGGAGAACT
GCGGCTTCGAATGGGCGGTGGACCTGCGCTATGCGGGCCAGGCCTTCGACCTGCGCGTGCCGCTGGACACGGCGGATTTC
TCGCCCCGTGGTGTCGCGGCGGCGACGAGCGCCTTCCACGCCATCCACAAGCAGCGCTTCTCCTATGACGAGCCCGCCGT
ACCGGTGGAGATCGTGGCCCTGCGCCTCACCGCCATCGGCCGCCTCGCCAAGCCGACCCCGGCGCCCGCCTCGGCCGGTA
CGGTCTCCGGTTCGAAGACCCGCCCCGTCTATGGGCGCGGCGGCTTTGTCGAGACCAAGGTTTGGGCGCGCGAGGCCATC
GGCCCCGAGGGCGTGCCCGGCCCGGCCGTGGTGGAGGAGACCTACACGGCCACTTATGTGCCTGCCGGCTGGACCATCCG
CGCCCATGCCACGGGCGCGCTCATCGCCGAGCGCGCGGCCACCCACTGA

Upstream 100 bases:

>100_bases
GTTGTGGGCGCGCAATACGCCCTCATCCGCTCCGCCTTCCACGGCCTCGTGGACAGCCTCGGCTCCGAAGGCCTCCTGTG
ATCCTCATCCGGAACGTGTC

Downstream 100 bases:

>100_bases
TCGCCTCCAAGGACAAGAGCCATGAGCCCCATCGATCCCGTCCGCCTCGAGGTGATCCGCAATGCGCTGGTCGCCGCCGC
CGAGGAAATGAGCATCACCA

Product: 5-oxoprolinase

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MTSQAPIRIAVDIGGTFTDIEILDASTGEIHQMKTPSTPSDPSIGLLTGIKEASARFGFSLDQVQYLLHGTTIATNAVLE
RKLPLGAVVTTAGFEDVMQIGRHGRTDVYAITASPPAPLVKRRLCFGVSERIGADGRVLKPLDDRSVAFLAGKLREAEVK
SVAICFLHAYANPAHERRAGEILRELLPGVAITLSSDISPELREYERMSTTVLNAMLVPVVQTYTDRLAGKLKEEVPSTQ
VYLVQSNGGVSGLAKAGREPARLLLSGPSGGAAAAKRLAADLDEPNLVAVDMGGTSFDVSVVHEGAVAMVNEGEVDGLPV
RLPMIEMRTIGAGGGSIAWVDDGGRLRIGPHSAGAEPGPACYGRGGQQLTVTDANLLLGRLDGSSFMGGKMGLDRDAAAK
AAEAVSAKLGLSPEETAAGVIAVTNSSLATATRLSLFEKGMDPEDFALLSFGGAGGVHACEVAEELGMRKVIFPAHASTL
SAWGILWSDITHDLSATQIGLFSDLAPSMAQKAQALAAEANRLLAEDGVRPENCGFEWAVDLRYAGQAFDLRVPLDTADF
SPRGVAAATSAFHAIHKQRFSYDEPAVPVEIVALRLTAIGRLAKPTPAPASAGTVSGSKTRPVYGRGGFVETKVWAREAI
GPEGVPGPAVVEETYTATYVPAGWTIRAHATGALIAERAATH

Sequences:

>Translated_682_residues
MTSQAPIRIAVDIGGTFTDIEILDASTGEIHQMKTPSTPSDPSIGLLTGIKEASARFGFSLDQVQYLLHGTTIATNAVLE
RKLPLGAVVTTAGFEDVMQIGRHGRTDVYAITASPPAPLVKRRLCFGVSERIGADGRVLKPLDDRSVAFLAGKLREAEVK
SVAICFLHAYANPAHERRAGEILRELLPGVAITLSSDISPELREYERMSTTVLNAMLVPVVQTYTDRLAGKLKEEVPSTQ
VYLVQSNGGVSGLAKAGREPARLLLSGPSGGAAAAKRLAADLDEPNLVAVDMGGTSFDVSVVHEGAVAMVNEGEVDGLPV
RLPMIEMRTIGAGGGSIAWVDDGGRLRIGPHSAGAEPGPACYGRGGQQLTVTDANLLLGRLDGSSFMGGKMGLDRDAAAK
AAEAVSAKLGLSPEETAAGVIAVTNSSLATATRLSLFEKGMDPEDFALLSFGGAGGVHACEVAEELGMRKVIFPAHASTL
SAWGILWSDITHDLSATQIGLFSDLAPSMAQKAQALAAEANRLLAEDGVRPENCGFEWAVDLRYAGQAFDLRVPLDTADF
SPRGVAAATSAFHAIHKQRFSYDEPAVPVEIVALRLTAIGRLAKPTPAPASAGTVSGSKTRPVYGRGGFVETKVWAREAI
GPEGVPGPAVVEETYTATYVPAGWTIRAHATGALIAERAATH
>Mature_681_residues
TSQAPIRIAVDIGGTFTDIEILDASTGEIHQMKTPSTPSDPSIGLLTGIKEASARFGFSLDQVQYLLHGTTIATNAVLER
KLPLGAVVTTAGFEDVMQIGRHGRTDVYAITASPPAPLVKRRLCFGVSERIGADGRVLKPLDDRSVAFLAGKLREAEVKS
VAICFLHAYANPAHERRAGEILRELLPGVAITLSSDISPELREYERMSTTVLNAMLVPVVQTYTDRLAGKLKEEVPSTQV
YLVQSNGGVSGLAKAGREPARLLLSGPSGGAAAAKRLAADLDEPNLVAVDMGGTSFDVSVVHEGAVAMVNEGEVDGLPVR
LPMIEMRTIGAGGGSIAWVDDGGRLRIGPHSAGAEPGPACYGRGGQQLTVTDANLLLGRLDGSSFMGGKMGLDRDAAAKA
AEAVSAKLGLSPEETAAGVIAVTNSSLATATRLSLFEKGMDPEDFALLSFGGAGGVHACEVAEELGMRKVIFPAHASTLS
AWGILWSDITHDLSATQIGLFSDLAPSMAQKAQALAAEANRLLAEDGVRPENCGFEWAVDLRYAGQAFDLRVPLDTADFS
PRGVAAATSAFHAIHKQRFSYDEPAVPVEIVALRLTAIGRLAKPTPAPASAGTVSGSKTRPVYGRGGFVETKVWAREAIG
PEGVPGPAVVEETYTATYVPAGWTIRAHATGALIAERAATH

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=721, Percent_Identity=29.9583911234397, Blast_Score=224, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI133901900, Length=710, Percent_Identity=26.1971830985915, Blast_Score=185, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6322634, Length=609, Percent_Identity=32.183908045977, Blast_Score=238, Evalue=2e-63,
Organism=Drosophila melanogaster, GI45550492, Length=728, Percent_Identity=29.9450549450549, Blast_Score=248, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71376; Mature: 71245

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQAPIRIAVDIGGTFTDIEILDASTGEIHQMKTPSTPSDPSIGLLTGIKEASARFGFS
CCCCCCEEEEEECCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHCCHHHHHHCCCC
LDQVQYLLHGTTIATNAVLERKLPLGAVVTTAGFEDVMQIGRHGRTDVYAITASPPAPLV
HHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCCCHHH
KRRLCFGVSERIGADGRVLKPLDDRSVAFLAGKLREAEVKSVAICFLHAYANPAHERRAG
HHHHHHCHHHHCCCCCCEECCCCCCCEEEHHHHHHHHHHHHHEEEEEEHHCCCHHHHHHH
EILRELLPGVAITLSSDISPELREYERMSTTVLNAMLVPVVQTYTDRLAGKLKEEVPSTQ
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VYLVQSNGGVSGLAKAGREPARLLLSGPSGGAAAAKRLAADLDEPNLVAVDMGGTSFDVS
EEEEECCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEE
VVHEGAVAMVNEGEVDGLPVRLPMIEMRTIGAGGGSIAWVDDGGRLRIGPHSAGAEPGPA
EEECCEEEEEECCCCCCEEEEECEEEEEEECCCCCEEEEEECCCEEEECCCCCCCCCCCC
CYGRGGQQLTVTDANLLLGRLDGSSFMGGKMGLDRDAAAKAAEAVSAKLGLSPEETAAGV
CCCCCCCEEEEEEHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCEE
IAVTNSSLATATRLSLFEKGMDPEDFALLSFGGAGGVHACEVAEELGMRKVIFPAHASTL
EEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCHHH
SAWGILWSDITHDLSATQIGLFSDLAPSMAQKAQALAAEANRLLAEDGVRPENCGFEWAV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
DLRYAGQAFDLRVPLDTADFSPRGVAAATSAFHAIHKQRFSYDEPAVPVEIVALRLTAIG
EEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RLAKPTPAPASAGTVSGSKTRPVYGRGGFVETKVWAREAIGPEGVPGPAVVEETYTATYV
HCCCCCCCCCCCCCCCCCCCCCEECCCCEEEHHHHHHHCCCCCCCCCCCEEECCCEEEEE
PAGWTIRAHATGALIAERAATH
CCCEEEEECCCHHHHHHHHCCC
>Mature Secondary Structure 
TSQAPIRIAVDIGGTFTDIEILDASTGEIHQMKTPSTPSDPSIGLLTGIKEASARFGFS
CCCCCEEEEEECCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHCCHHHHHHCCCC
LDQVQYLLHGTTIATNAVLERKLPLGAVVTTAGFEDVMQIGRHGRTDVYAITASPPAPLV
HHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCCCHHH
KRRLCFGVSERIGADGRVLKPLDDRSVAFLAGKLREAEVKSVAICFLHAYANPAHERRAG
HHHHHHCHHHHCCCCCCEECCCCCCCEEEHHHHHHHHHHHHHEEEEEEHHCCCHHHHHHH
EILRELLPGVAITLSSDISPELREYERMSTTVLNAMLVPVVQTYTDRLAGKLKEEVPSTQ
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VYLVQSNGGVSGLAKAGREPARLLLSGPSGGAAAAKRLAADLDEPNLVAVDMGGTSFDVS
EEEEECCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEE
VVHEGAVAMVNEGEVDGLPVRLPMIEMRTIGAGGGSIAWVDDGGRLRIGPHSAGAEPGPA
EEECCEEEEEECCCCCCEEEEECEEEEEEECCCCCEEEEEECCCEEEECCCCCCCCCCCC
CYGRGGQQLTVTDANLLLGRLDGSSFMGGKMGLDRDAAAKAAEAVSAKLGLSPEETAAGV
CCCCCCCEEEEEEHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCEE
IAVTNSSLATATRLSLFEKGMDPEDFALLSFGGAGGVHACEVAEELGMRKVIFPAHASTL
EEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCHHH
SAWGILWSDITHDLSATQIGLFSDLAPSMAQKAQALAAEANRLLAEDGVRPENCGFEWAV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
DLRYAGQAFDLRVPLDTADFSPRGVAAATSAFHAIHKQRFSYDEPAVPVEIVALRLTAIG
EEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RLAKPTPAPASAGTVSGSKTRPVYGRGGFVETKVWAREAIGPEGVPGPAVVEETYTATYV
HCCCCCCCCCCCCCCCCCCCCCEECCCCEEEHHHHHHHCCCCCCCCCCCEEECCCEEEEE
PAGWTIRAHATGALIAERAATH
CCCEEEEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]