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The map label for this gene is 158423420

Identifier: 158423420

GI number: 158423420

Start: 2055581

End: 2057326

Strand: Reverse

Name: 158423420

Synonym: AZC_1796

Alternate gene names: NA

Gene position: 2057326-2055581 (Counterclockwise)

Preceding gene: 158423421

Following gene: 158423419

Centisome position: 38.31

GC content: 67.64

Gene sequence:

>1746_bases
ATGAGCCCCATCGATCCCGTCCGCCTCGAGGTGATCCGCAATGCGCTGGTCGCCGCCGCCGAGGAAATGAGCATCACCAT
CTGGCGCACCAGCCGCTCCACGGTCGTACGCGAGATCCTCGATTTCTCCACCGCCGTCTTTGATGCGCAGGGGCGCAACA
TCGCCCAGTCGGCGCGCATTCCGGTGCACCTCAACTCCATGTCGGACTGCCTGAAGACCATTCTGGAGCAGTACATTCCG
CTGGAGAGCTGGAACGAGGGCGACGTCATCGTCACCAACGATCCCTATGCCGGCGGCCAGCATTTGCCGGACATCCAGAC
CTTCCGGCCGGTGTTCGTGGATGGCGAGCGCGTCGGCATCGTCGGCACCCTCTGCCACCATGTGGATGTGGGCGGGGGAG
CTGCCGGCTCCTATTATGCGGCGGCCACCGAGATCTTCCACGAAGGCATCCGCATTCCCCCACTGCGCCTCGTGGACAAG
GGCACGCTCAACACCGGCGTGTTCGAGATGCTGCTCTACAACGTGCGCCAGCCGGATGAGACGCGCGGCGACCTCAACGC
CCAGATCGCCGCGCTCGGCATCGGCGCGCGGGCAGTGGCGCGCATCGCGAAGAAGTATGGCAGCGCCAACCTCTCCGCCG
CCATGTCCGCCATCCTCGACGGCTCCGAGCGCATGATGCGCGCGGCCATCGCCGCTTTGCCGGACGGCACCGCCTCCTTC
GTGGAGACGGTGGATGACGACGGCCAGTCGGACACGCCCATCCGCCTTGAGATCACCATCACCAAGAAGGGCGACACCAT
CGCGCTCGACTTCGCCGGCTCCAGCCCGCAGGTGCGTGGCCCGGTGAACAACACGCCGGCCATGACCTGCTCGGCGGTCT
ATTACGCCCTGCTGGCGGCACTGGGCTCGGACATTCCGGCCAATTCCGGCTGCTACCGGCCCGTGAGCGTGAATCTGCCC
AAAGGCAGCGTCGTGAACGCCCAGTTCCCCGCCCCCGTCGTCGGCCGCATGGTGGTGAACCACCGCATCGCCACCTGCGT
CTTCGGCGCGCTGGCCCAGATCGCGCCGGAGCGCATTCCAGCGGCCTATTACGCCATCTCCTATGTCTATGCGGTCTCGC
TGGTGCAGCCGAACGCCAAGCGCCAGGTCTATTTCGACATCGAGGTGGGCGGCTGGGGCGGCCATGCGGGCGGTGATGGC
GCGAGCGCCCTCTCCTGCGGCCTCCACAACAACACCAATGCCCCCATCGAGATGGTGGAAGCCAAATACCCCGTGGTGTT
CACCCGCTACGGCCTGCTGCCGGATTCAGGCGGCGCCGGCACCCATCGCGGCGGCCTCGGCCTCGTGCGCGAGTTCCGGC
TGGAGGCGGCGGAAGGCTCCCTCTCCACCAATTTCGAGCGCTTCCGCTTCCCGCCCTATGGCATCAAGGGCGGCGAGCCG
GGCTCGCTCTCTTCGACCACCGTCACCCATGCGGACGGCACCACCGCGAGCCTCAATTCCAAGGTCTCCGGCATTCCGCT
CTCCGCCGGTGATCTCGTGACCATCAAGACGTCCGGCGGCGGCGGCTTCGGCGACCCGAAGGGCCGCGACCGGGCCAAGC
TCGCCGAGGATCTGGCGGAAGGCCTCGTGACGCCCGAGGCGGCCCGCACCCTCTATGGCGCGCCCGAGCTTGCCGCCGCG
GCCGCCACCGTCAAGACCTGTGGCAGCAAGAGCCCTGCCCGCGCTAAGACCGGGGTCGCCGCATGA

Upstream 100 bases:

>100_bases
CACTTATGTGCCTGCCGGCTGGACCATCCGCGCCCATGCCACGGGCGCGCTCATCGCCGAGCGCGCGGCCACCCACTGAT
CGCCTCCAAGGACAAGAGCC

Downstream 100 bases:

>100_bases
GCGCCCCGGCATCCGTCCCCATGGCCTCCCTCTCCCTTGCCGAGGTGGAGGCCCTCACCCGAGCCGCCTTACAGGCGAGC
GGCGTCAGCCCGGCCAATGA

Product: N-methylhydantoinase B

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MSPIDPVRLEVIRNALVAAAEEMSITIWRTSRSTVVREILDFSTAVFDAQGRNIAQSARIPVHLNSMSDCLKTILEQYIP
LESWNEGDVIVTNDPYAGGQHLPDIQTFRPVFVDGERVGIVGTLCHHVDVGGGAAGSYYAAATEIFHEGIRIPPLRLVDK
GTLNTGVFEMLLYNVRQPDETRGDLNAQIAALGIGARAVARIAKKYGSANLSAAMSAILDGSERMMRAAIAALPDGTASF
VETVDDDGQSDTPIRLEITITKKGDTIALDFAGSSPQVRGPVNNTPAMTCSAVYYALLAALGSDIPANSGCYRPVSVNLP
KGSVVNAQFPAPVVGRMVVNHRIATCVFGALAQIAPERIPAAYYAISYVYAVSLVQPNAKRQVYFDIEVGGWGGHAGGDG
ASALSCGLHNNTNAPIEMVEAKYPVVFTRYGLLPDSGGAGTHRGGLGLVREFRLEAAEGSLSTNFERFRFPPYGIKGGEP
GSLSSTTVTHADGTTASLNSKVSGIPLSAGDLVTIKTSGGGGFGDPKGRDRAKLAEDLAEGLVTPEAARTLYGAPELAAA
AATVKTCGSKSPARAKTGVAA

Sequences:

>Translated_581_residues
MSPIDPVRLEVIRNALVAAAEEMSITIWRTSRSTVVREILDFSTAVFDAQGRNIAQSARIPVHLNSMSDCLKTILEQYIP
LESWNEGDVIVTNDPYAGGQHLPDIQTFRPVFVDGERVGIVGTLCHHVDVGGGAAGSYYAAATEIFHEGIRIPPLRLVDK
GTLNTGVFEMLLYNVRQPDETRGDLNAQIAALGIGARAVARIAKKYGSANLSAAMSAILDGSERMMRAAIAALPDGTASF
VETVDDDGQSDTPIRLEITITKKGDTIALDFAGSSPQVRGPVNNTPAMTCSAVYYALLAALGSDIPANSGCYRPVSVNLP
KGSVVNAQFPAPVVGRMVVNHRIATCVFGALAQIAPERIPAAYYAISYVYAVSLVQPNAKRQVYFDIEVGGWGGHAGGDG
ASALSCGLHNNTNAPIEMVEAKYPVVFTRYGLLPDSGGAGTHRGGLGLVREFRLEAAEGSLSTNFERFRFPPYGIKGGEP
GSLSSTTVTHADGTTASLNSKVSGIPLSAGDLVTIKTSGGGGFGDPKGRDRAKLAEDLAEGLVTPEAARTLYGAPELAAA
AATVKTCGSKSPARAKTGVAA
>Mature_580_residues
SPIDPVRLEVIRNALVAAAEEMSITIWRTSRSTVVREILDFSTAVFDAQGRNIAQSARIPVHLNSMSDCLKTILEQYIPL
ESWNEGDVIVTNDPYAGGQHLPDIQTFRPVFVDGERVGIVGTLCHHVDVGGGAAGSYYAAATEIFHEGIRIPPLRLVDKG
TLNTGVFEMLLYNVRQPDETRGDLNAQIAALGIGARAVARIAKKYGSANLSAAMSAILDGSERMMRAAIAALPDGTASFV
ETVDDDGQSDTPIRLEITITKKGDTIALDFAGSSPQVRGPVNNTPAMTCSAVYYALLAALGSDIPANSGCYRPVSVNLPK
GSVVNAQFPAPVVGRMVVNHRIATCVFGALAQIAPERIPAAYYAISYVYAVSLVQPNAKRQVYFDIEVGGWGGHAGGDGA
SALSCGLHNNTNAPIEMVEAKYPVVFTRYGLLPDSGGAGTHRGGLGLVREFRLEAAEGSLSTNFERFRFPPYGIKGGEPG
SLSSTTVTHADGTTASLNSKVSGIPLSAGDLVTIKTSGGGGFGDPKGRDRAKLAEDLAEGLVTPEAARTLYGAPELAAAA
ATVKTCGSKSPARAKTGVAA

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=563, Percent_Identity=32.1492007104796, Blast_Score=231, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI133901900, Length=556, Percent_Identity=30.5755395683453, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI133901902, Length=521, Percent_Identity=30.3262955854127, Blast_Score=201, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6322634, Length=558, Percent_Identity=31.3620071684588, Blast_Score=237, Evalue=4e-63,
Organism=Drosophila melanogaster, GI45550492, Length=541, Percent_Identity=32.1626617375231, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 60905; Mature: 60773

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIDPVRLEVIRNALVAAAEEMSITIWRTSRSTVVREILDFSTAVFDAQGRNIAQSARI
CCCCCHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHEECCCCCCCHHHCCC
PVHLNSMSDCLKTILEQYIPLESWNEGDVIVTNDPYAGGQHLPDIQTFRPVFVDGERVGI
CEEECHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCCEEECCCEEEH
VGTLCHHVDVGGGAAGSYYAAATEIFHEGIRIPPLRLVDKGTLNTGVFEMLLYNVRQPDE
HHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCC
TRGDLNAQIAALGIGARAVARIAKKYGSANLSAAMSAILDGSERMMRAAIAALPDGTASF
CCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
VETVDDDGQSDTPIRLEITITKKGDTIALDFAGSSPQVRGPVNNTPAMTCSAVYYALLAA
HHHHCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGSDIPANSGCYRPVSVNLPKGSVVNAQFPAPVVGRMVVNHRIATCVFGALAQIAPERIP
HCCCCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AAYYAISYVYAVSLVQPNAKRQVYFDIEVGGWGGHAGGDGASALSCGLHNNTNAPIEMVE
HHHHHHHHHHHHHEECCCCCCEEEEEEEECCCCCCCCCCCCHHEEECCCCCCCCCEEEEE
AKYPVVFTRYGLLPDSGGAGTHRGGLGLVREFRLEAAEGSLSTNFERFRFPPYGIKGGEP
CCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCC
GSLSSTTVTHADGTTASLNSKVSGIPLSAGDLVTIKTSGGGGFGDPKGRDRAKLAEDLAE
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
GLVTPEAARTLYGAPELAAAAATVKTCGSKSPARAKTGVAA
CCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPIDPVRLEVIRNALVAAAEEMSITIWRTSRSTVVREILDFSTAVFDAQGRNIAQSARI
CCCCHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHEECCCCCCCHHHCCC
PVHLNSMSDCLKTILEQYIPLESWNEGDVIVTNDPYAGGQHLPDIQTFRPVFVDGERVGI
CEEECHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCCEEECCCEEEH
VGTLCHHVDVGGGAAGSYYAAATEIFHEGIRIPPLRLVDKGTLNTGVFEMLLYNVRQPDE
HHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCC
TRGDLNAQIAALGIGARAVARIAKKYGSANLSAAMSAILDGSERMMRAAIAALPDGTASF
CCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
VETVDDDGQSDTPIRLEITITKKGDTIALDFAGSSPQVRGPVNNTPAMTCSAVYYALLAA
HHHHCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGSDIPANSGCYRPVSVNLPKGSVVNAQFPAPVVGRMVVNHRIATCVFGALAQIAPERIP
HCCCCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AAYYAISYVYAVSLVQPNAKRQVYFDIEVGGWGGHAGGDGASALSCGLHNNTNAPIEMVE
HHHHHHHHHHHHHEECCCCCCEEEEEEEECCCCCCCCCCCCHHEEECCCCCCCCCEEEEE
AKYPVVFTRYGLLPDSGGAGTHRGGLGLVREFRLEAAEGSLSTNFERFRFPPYGIKGGEP
CCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCC
GSLSSTTVTHADGTTASLNSKVSGIPLSAGDLVTIKTSGGGGFGDPKGRDRAKLAEDLAE
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
GLVTPEAARTLYGAPELAAAAATVKTCGSKSPARAKTGVAA
CCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]