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The map label for this gene is allD [C]

Identifier: 158423419

GI number: 158423419

Start: 2054559

End: 2055584

Strand: Reverse

Name: allD [C]

Synonym: AZC_1795

Alternate gene names: 158423419

Gene position: 2055584-2054559 (Counterclockwise)

Preceding gene: 158423420

Following gene: 158423413

Centisome position: 38.28

GC content: 72.03

Gene sequence:

>1026_bases
ATGAGCGCCCCGGCATCCGTCCCCATGGCCTCCCTCTCCCTTGCCGAGGTGGAGGCCCTCACCCGAGCCGCCTTACAGGC
GAGCGGCGTCAGCCCGGCCAATGAGCCCTCCGTCACCGCCTCGGTCGTGGCGGCAGAGGCGGAAGGCGTGCACAGCCACG
GCCTCGCCCGCCTGCCCACCTATTGCGCCCATGCCAAGGTGGGCAAGATCGACGGCAAGGCCACGCCCACCCTCTCCCGC
CCGCGCCCCGGCCTGGTGCGCGTGGATGCCGCGGACGGCTTCGCCCATCCGGCCATCGACCTCGGCCTGCCGGCCCTTCT
CGATGCCGCGCGAGCACAGGGCATCGCGGCGCTGGCGGTGACCAACTCCTACAATTGCGGCGTTGTCGGCTATCACGTGG
AGCGCATCGCGAAGGCAGGCCTGATGGCGCTCGGCTTCGTGAATGCGCCCGCCTCCATCGCACCCGTGGGGGGCACGAAG
CCGGTGTTCGGCACCAACCCGATCGCCTTCGCCGTGCCCCGCGCCGATGGCGAACCGCTGGTGCTGGATCAGTCCTCCAG
CGTGGTGGCGAAAAGCGAGATCGTGGTCCACGACCAGCGGGGAGAAGCCATTCCCCTCGGCTGGGCCCTGGACAAGGCCG
GCCAGCCCACCACGGACCCGAAGGCGGCGCTCGCCGGCGGAACCATGGTGCCCGCAGGCGGCTACAAGGGCGCGGGGCTT
GCGCTCATCGTGGAGATGTTCGCGGCCTGGCTCACGGGCGCGCATCTCTCCATCGATGCCTCCTCCTTCGCGGACAATAC
GGGCGGCTCGCCGCGCACGGGCCAGATGTTCATCGCCGTCGATCCCGGCCCGCTCGCCGGGCCGAGCGCGGCGGCGCGGA
TGGCCCATCTGTTCGCCGCCATCACCGATCAGGAGGGTGCGCGCCTTCCCGGCGGGCGGCGCGCGGCGGCACGGGTGCGC
ACCGCGCGCGAGGGCGTGAAGATCCCTCAGGCGCTGCTGGACAAGCTGACGGCCATCGCCGGCTGA

Upstream 100 bases:

>100_bases
CCCGCACCCTCTATGGCGCGCCCGAGCTTGCCGCCGCGGCCGCCACCGTCAAGACCTGTGGCAGCAAGAGCCCTGCCCGC
GCTAAGACCGGGGTCGCCGC

Downstream 100 bases:

>100_bases
TCCTATGCGGGGGCGGGTACACCCGCTCCCGCCTCATACCGGCAGGCGGAAGTGCAGTTCCCACGAACTGCCGATGCGCT
GGATCTTCAGGTCCGGCGCG

Product: malate/L-lactate dehydrogenase family protein

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSAPASVPMASLSLAEVEALTRAALQASGVSPANEPSVTASVVAAEAEGVHSHGLARLPTYCAHAKVGKIDGKATPTLSR
PRPGLVRVDAADGFAHPAIDLGLPALLDAARAQGIAALAVTNSYNCGVVGYHVERIAKAGLMALGFVNAPASIAPVGGTK
PVFGTNPIAFAVPRADGEPLVLDQSSSVVAKSEIVVHDQRGEAIPLGWALDKAGQPTTDPKAALAGGTMVPAGGYKGAGL
ALIVEMFAAWLTGAHLSIDASSFADNTGGSPRTGQMFIAVDPGPLAGPSAAARMAHLFAAITDQEGARLPGGRRAAARVR
TAREGVKIPQALLDKLTAIAG

Sequences:

>Translated_341_residues
MSAPASVPMASLSLAEVEALTRAALQASGVSPANEPSVTASVVAAEAEGVHSHGLARLPTYCAHAKVGKIDGKATPTLSR
PRPGLVRVDAADGFAHPAIDLGLPALLDAARAQGIAALAVTNSYNCGVVGYHVERIAKAGLMALGFVNAPASIAPVGGTK
PVFGTNPIAFAVPRADGEPLVLDQSSSVVAKSEIVVHDQRGEAIPLGWALDKAGQPTTDPKAALAGGTMVPAGGYKGAGL
ALIVEMFAAWLTGAHLSIDASSFADNTGGSPRTGQMFIAVDPGPLAGPSAAARMAHLFAAITDQEGARLPGGRRAAARVR
TAREGVKIPQALLDKLTAIAG
>Mature_340_residues
SAPASVPMASLSLAEVEALTRAALQASGVSPANEPSVTASVVAAEAEGVHSHGLARLPTYCAHAKVGKIDGKATPTLSRP
RPGLVRVDAADGFAHPAIDLGLPALLDAARAQGIAALAVTNSYNCGVVGYHVERIAKAGLMALGFVNAPASIAPVGGTKP
VFGTNPIAFAVPRADGEPLVLDQSSSVVAKSEIVVHDQRGEAIPLGWALDKAGQPTTDPKAALAGGTMVPAGGYKGAGLA
LIVEMFAAWLTGAHLSIDASSFADNTGGSPRTGQMFIAVDPGPLAGPSAAARMAHLFAAITDQEGARLPGGRRAAARVRT
AREGVKIPQALLDKLTAIAG

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=339, Percent_Identity=27.1386430678466, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787020, Length=338, Percent_Identity=25.7396449704142, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790000, Length=338, Percent_Identity=23.0769230769231, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17507179, Length=293, Percent_Identity=26.2798634812287, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17536633, Length=309, Percent_Identity=26.537216828479, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24667908, Length=293, Percent_Identity=27.3037542662116, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI45553211, Length=293, Percent_Identity=27.3037542662116, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24667912, Length=293, Percent_Identity=27.3037542662116, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24667904, Length=293, Percent_Identity=27.3037542662116, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24658010, Length=343, Percent_Identity=26.8221574344023, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24648360, Length=264, Percent_Identity=26.8939393939394, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 34265; Mature: 34133

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPASVPMASLSLAEVEALTRAALQASGVSPANEPSVTASVVAAEAEGVHSHGLARLPT
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCHHCCCHHHHH
YCAHAKVGKIDGKATPTLSRPRPGLVRVDAADGFAHPAIDLGLPALLDAARAQGIAALAV
HHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHCHHHHHHHHHHCCEEEEEE
TNSYNCGVVGYHVERIAKAGLMALGFVNAPASIAPVGGTKPVFGTNPIAFAVPRADGEPL
ECCCCCCEEHHHHHHHHHHHHHEEEEECCCCCEECCCCCCCCCCCCCEEEEEECCCCCEE
VLDQSSSVVAKSEIVVHDQRGEAIPLGWALDKAGQPTTDPKAALAGGTMVPAGGYKGAGL
EEECCCCEEEEEEEEEECCCCCEEEECEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCHH
ALIVEMFAAWLTGAHLSIDASSFADNTGGSPRTGQMFIAVDPGPLAGPSAAARMAHLFAA
HHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ITDQEGARLPGGRRAAARVRTAREGVKIPQALLDKLTAIAG
HCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SAPASVPMASLSLAEVEALTRAALQASGVSPANEPSVTASVVAAEAEGVHSHGLARLPT
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCHHCCCHHHHH
YCAHAKVGKIDGKATPTLSRPRPGLVRVDAADGFAHPAIDLGLPALLDAARAQGIAALAV
HHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHCHHHHHHHHHHCCEEEEEE
TNSYNCGVVGYHVERIAKAGLMALGFVNAPASIAPVGGTKPVFGTNPIAFAVPRADGEPL
ECCCCCCEEHHHHHHHHHHHHHEEEEECCCCCEECCCCCCCCCCCCCEEEEEECCCCCEE
VLDQSSSVVAKSEIVVHDQRGEAIPLGWALDKAGQPTTDPKAALAGGTMVPAGGYKGAGL
EEECCCCEEEEEEEEEECCCCCEEEECEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCHH
ALIVEMFAAWLTGAHLSIDASSFADNTGGSPRTGQMFIAVDPGPLAGPSAAARMAHLFAA
HHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ITDQEGARLPGGRRAAARVRTAREGVKIPQALLDKLTAIAG
HCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]