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The map label for this gene is fabZ

Identifier: 158423327

GI number: 158423327

Start: 1951322

End: 1951798

Strand: Direct

Name: fabZ

Synonym: AZC_1703

Alternate gene names: 158423327

Gene position: 1951322-1951798 (Clockwise)

Preceding gene: 158423326

Following gene: 158423328

Centisome position: 36.34

GC content: 63.31

Gene sequence:

>477_bases
ATGAGCGAAGAAACCAAGGCGGACGAGACGAAGGTTCTGGACAGCATCGACATCCTGCGCATCCTGGCGCTCCTGCCGCA
TCGCTATCCGTTCCTGATGGTGGACCGGATCGAGGCGATCGACAGCGATCTGTCCTGCGTCGGCTACAAGAACGTGACGG
CCAACGAGCCGCACTTCCAGGGTCACTTCCCGAACAATCCGGTCATGCCGGGCGTGCTCATCATCGAGGGCATGGCCCAG
ACGGCGGGTGCCATCTGCATCCATGCCAAGGGCGCCGACCGCAAGCCTTCGCTGGTCTATTTCATGACCATCGACGAGGC
GAAGTTCCGTCGCCCGGTCCGCCCCGGCGACGTGCTCGAATATCACATGACCCGCCTCAACAAGCGCCGCAACATGTGGT
GGTACCGCGGCGAAGCCCGGGTGGGCGGAGAAATCGTGGCGGAGGCGCGTGTTGGCGCCATGATCGCCGAGGAGTGA

Upstream 100 bases:

>100_bases
CGGCCAAGCCGGTGCGCGAGTGGTTCCGCGAAATGACCACCTTGAAGAAGCTGGCTGAGTCGAGGGCGCGTTCCGGCGCC
GCGACGCCGGGGGAAGAAGA

Downstream 100 bases:

>100_bases
ACGTGGCCCTGATCGACCCGACTGCCCGCGTTGCCGATGGCGCGTGGCTCGCCGATGATGTGGAAGTTGGACCCTACTGC
ATCGTCGGCCCCGATGTGAC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSEETKADETKVLDSIDILRILALLPHRYPFLMVDRIEAIDSDLSCVGYKNVTANEPHFQGHFPNNPVMPGVLIIEGMAQ
TAGAICIHAKGADRKPSLVYFMTIDEAKFRRPVRPGDVLEYHMTRLNKRRNMWWYRGEARVGGEIVAEARVGAMIAEE

Sequences:

>Translated_158_residues
MSEETKADETKVLDSIDILRILALLPHRYPFLMVDRIEAIDSDLSCVGYKNVTANEPHFQGHFPNNPVMPGVLIIEGMAQ
TAGAICIHAKGADRKPSLVYFMTIDEAKFRRPVRPGDVLEYHMTRLNKRRNMWWYRGEARVGGEIVAEARVGAMIAEE
>Mature_157_residues
SEETKADETKVLDSIDILRILALLPHRYPFLMVDRIEAIDSDLSCVGYKNVTANEPHFQGHFPNNPVMPGVLIIEGMAQT
AGAICIHAKGADRKPSLVYFMTIDEAKFRRPVRPGDVLEYHMTRLNKRRNMWWYRGEARVGGEIVAEARVGAMIAEE

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=135, Percent_Identity=45.9259259259259, Blast_Score=129, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_AZOC5 (A8I489)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524619.1
- ProteinModelPortal:   A8I489
- SMR:   A8I489
- GeneID:   5688144
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1703
- HOGENOM:   HBG433282
- OMA:   EFTQKRS
- ProtClustDB:   PRK00006
- BioCyc:   ACAU438753:AZC_1703-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17869; Mature: 17738

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: ACT_SITE 62-62

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEETKADETKVLDSIDILRILALLPHRYPFLMVDRIEAIDSDLSCVGYKNVTANEPHFQ
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCEEECCCCCCCCCCCC
GHFPNNPVMPGVLIIEGMAQTAGAICIHAKGADRKPSLVYFMTIDEAKFRRPVRPGDVLE
CCCCCCCCCCCEEEEECHHHCCCEEEEEECCCCCCCCEEEEEEECHHHHCCCCCCCHHHH
YHMTRLNKRRNMWWYRGEARVGGEIVAEARVGAMIAEE
HHHHHHHHHCCCEEEECCCCCCCEEEEHHHHCEEECCC
>Mature Secondary Structure 
SEETKADETKVLDSIDILRILALLPHRYPFLMVDRIEAIDSDLSCVGYKNVTANEPHFQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCEEECCCCCCCCCCCC
GHFPNNPVMPGVLIIEGMAQTAGAICIHAKGADRKPSLVYFMTIDEAKFRRPVRPGDVLE
CCCCCCCCCCCEEEEECHHHCCCEEEEEECCCCCCCCEEEEEEECHHHHCCCCCCCHHHH
YHMTRLNKRRNMWWYRGEARVGGEIVAEARVGAMIAEE
HHHHHHHHHCCCEEEECCCCCCCEEEEHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA