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The map label for this gene is fhuD [H]

Identifier: 158423248

GI number: 158423248

Start: 1854632

End: 1855513

Strand: Reverse

Name: fhuD [H]

Synonym: AZC_1624

Alternate gene names: 158423248

Gene position: 1855513-1854632 (Counterclockwise)

Preceding gene: 158423249

Following gene: 158423247

Centisome position: 34.55

GC content: 71.54

Gene sequence:

>882_bases
GTGACCGGCCTCTCCCGCCGCGCGCTTCTGGCGGCCCTTGGCCTTGCCGGCGTCTCGCGGGCAAGGGCTGCCTCGCCCCT
GCGGGTCGCGACGCTGGACTGGGCGCTGCTGGAGACCCTGCTGGCCCTCGGCGTGGTGCCGGTCGCGGCGGCGGAACTGG
TGCTCTATCGGCGGCAGGTCATCGAGCCGGCCGTGCCGGAGAGCGTCGCCGATCTCGGCCTGCGCGGCTCGCCCAGCTTC
GAGGCCCTGAAGCTGCTGGCGCCGGACCTGATCCTCGGCTCCAATTATACTGCCTGGGCTGAACCGACGCTCAGCCGCAT
TGCGCCGGTGGAGAGCTTCTCCATCTATGCACCCGGCGGGCATCCCTATGCTGCCGCCGAAGCTGCCACCCGCGCCATCG
CCAGTCGGCTCGACATGGCTCCCGCCGGCGCGGCGCTAATCGCCCTTGCGGATGCCGAGTTCGCGGCGCTGAAGGCGCGG
CTCACCGGCGGCGACGGGCGGCCGGCGCTGGTCATCAATCTGGGTGACGACCGGCATTTCCGTGTCTTCGGCGCCGACAG
CATGTTCGGCGAGGCGCTCACTTGCCTTGGTCTTGCCAATGCGTGGCGCGGCAGCACGCGCTATTCCGCCACCGCCCCCA
TGGGACTCGAGACGCTGGCGCAGGTGGGCGACGCCTGGATCGCACTGCTGCCGCCCGTGCCGCCCGAAGCACGCCGCATG
ATGGCGCAGAGCGCCTTCTGGAAGGCCCTGCCGAGCGTCCGCGCCGGACGGATCGTCGAACTGGCGCCCGTCAATCCTTT
CGGTGCCCTGCCCGCGGCCCTGCGTTTCGCACGCCTCCTCACCGATGCGCTCCCCTTTGCGAAGGCGGCCGCCCGTGGCT
GA

Upstream 100 bases:

>100_bases
CTGCCGATCTGGTGACGCCGGACCTGCTGGGCGCGCTCTATGGCCTGCCCATGGGGGTCATCCCCCATCCCGTGCGGGGC
GAACCCATGGGCTATGTGCT

Downstream 100 bases:

>100_bases
TGTCGCCCGCCTCCCCCGCCCCTTGCCTCGCGCACCACTGGCGGTGGCCGGGCTCGCCCTTCTGGCGCTGACCCTGTGCG
TCATGGGCCTGCTGCGGCAG

Product: ABC Fe+3 hydroxamate (ferrichrome) transporter

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein D; Ferrichrome-binding periplasmic protein; Iron(III)-hydroxamate-binding protein fhuD [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTGLSRRALLAALGLAGVSRARAASPLRVATLDWALLETLLALGVVPVAAAELVLYRRQVIEPAVPESVADLGLRGSPSF
EALKLLAPDLILGSNYTAWAEPTLSRIAPVESFSIYAPGGHPYAAAEAATRAIASRLDMAPAGAALIALADAEFAALKAR
LTGGDGRPALVINLGDDRHFRVFGADSMFGEALTCLGLANAWRGSTRYSATAPMGLETLAQVGDAWIALLPPVPPEARRM
MAQSAFWKALPSVRAGRIVELAPVNPFGALPAALRFARLLTDALPFAKAAARG

Sequences:

>Translated_293_residues
MTGLSRRALLAALGLAGVSRARAASPLRVATLDWALLETLLALGVVPVAAAELVLYRRQVIEPAVPESVADLGLRGSPSF
EALKLLAPDLILGSNYTAWAEPTLSRIAPVESFSIYAPGGHPYAAAEAATRAIASRLDMAPAGAALIALADAEFAALKAR
LTGGDGRPALVINLGDDRHFRVFGADSMFGEALTCLGLANAWRGSTRYSATAPMGLETLAQVGDAWIALLPPVPPEARRM
MAQSAFWKALPSVRAGRIVELAPVNPFGALPAALRFARLLTDALPFAKAAARG
>Mature_292_residues
TGLSRRALLAALGLAGVSRARAASPLRVATLDWALLETLLALGVVPVAAAELVLYRRQVIEPAVPESVADLGLRGSPSFE
ALKLLAPDLILGSNYTAWAEPTLSRIAPVESFSIYAPGGHPYAAAEAATRAIASRLDMAPAGAALIALADAEFAALKARL
TGGDGRPALVINLGDDRHFRVFGADSMFGEALTCLGLANAWRGSTRYSATAPMGLETLAQVGDAWIALLPPVPPEARRMM
AQSAFWKALPSVRAGRIVELAPVNPFGALPAALRFARLLTDALPFAKAAARG

Specific function: Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of all iron(3+)-hydroxamate siderophores such as ferrich

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786346, Length=293, Percent_Identity=33.1058020477816, Blast_Score=150, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008091
- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 30551; Mature: 30420

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLSRRALLAALGLAGVSRARAASPLRVATLDWALLETLLALGVVPVAAAELVLYRRQV
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEPAVPESVADLGLRGSPSFEALKLLAPDLILGSNYTAWAEPTLSRIAPVESFSIYAPGG
HCCCCCHHHHHCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHCCCCCEEEECCCC
HPYAAAEAATRAIASRLDMAPAGAALIALADAEFAALKARLTGGDGRPALVINLGDDRHF
CCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHEEEEECCCCCCEEEEECCCCCEE
RVFGADSMFGEALTCLGLANAWRGSTRYSATAPMGLETLAQVGDAWIALLPPVPPEARRM
EEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCHHHHHH
MAQSAFWKALPSVRAGRIVELAPVNPFGALPAALRFARLLTDALPFAKAAARG
HHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TGLSRRALLAALGLAGVSRARAASPLRVATLDWALLETLLALGVVPVAAAELVLYRRQV
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEPAVPESVADLGLRGSPSFEALKLLAPDLILGSNYTAWAEPTLSRIAPVESFSIYAPGG
HCCCCCHHHHHCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHCCCCCEEEECCCC
HPYAAAEAATRAIASRLDMAPAGAALIALADAEFAALKARLTGGDGRPALVINLGDDRHF
CCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHEEEEECCCCCCEEEEECCCCCEE
RVFGADSMFGEALTCLGLANAWRGSTRYSATAPMGLETLAQVGDAWIALLPPVPPEARRM
EEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCHHHHHH
MAQSAFWKALPSVRAGRIVELAPVNPFGALPAALRFARLLTDALPFAKAAARG
HHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301821; 2823072; 8202364; 9278503; 7651325; 10742172 [H]