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The map label for this gene is hlyD [H]

Identifier: 158423200

GI number: 158423200

Start: 1797525

End: 1798700

Strand: Direct

Name: hlyD [H]

Synonym: AZC_1576

Alternate gene names: 158423200

Gene position: 1797525-1798700 (Clockwise)

Preceding gene: 158423199

Following gene: 158423201

Centisome position: 33.47

GC content: 69.13

Gene sequence:

>1176_bases
GTGAGGTGGTGCATGGGCGGGGCGAAGCGGACGGGACGCTGGCGGTTTTATTTTCTGTTTTTCTGCCTTGTTGCGGCAGG
CGGGGCCGGCTGGGCGTGGTCGCAGGGGCTCATCGGCAAGGGCGGTGGTACGGCCAAGGCGCAGAGCCAGCCGGAGCGGC
GGGTCGCCGTCGTCGTCGCCACCGCGCAGGACAGGCCCATGCCGGTGCGCATCGAGGCCCTCGGTACGGTGGAGCCTCAG
GTTACGGTGACCATCCGCTCCCGCGTCGCCAGCCAGGTCACCAGTGTCGCCTTCGAGGACGGCGCCGTCGTCAACAAGGG
CGACCTCCTCTTCCAGCTCGATCCGCGCGAGGTGGATGCGCAGATCCTTCAGGCCCGCGCCACCCTCGCCAAGGACAAGA
CCCAGCTTGAGAAGGCCCTGCGCGACATGGAGCGCTATTCGGGCCTTGCCGCGCGCAACACGGTCTCGCAGGTGACGCTG
GACGACGCGCGCACCACCGCCGACGCCCAGAAGGCGACCGTCGATCAGGACGAGGCGAACCTGAAGGCGCTGGAGGTGCA
GCGCACCTATTATGACATCCGCTCGCCCGCGTCCGGCCGCCTCGGCGTCGCGGCGGTGCGGCCCGGCGCGGTGATCCGGG
TGGACGACACCCTCGCCACCGTGCGCCAGATCAAGCCCATCTATGTCGCCTTCGGCGTGCCCGAGCACTATCTGCGCGAC
ATCCGCGCGGCCCAGAATGACGCGAAGGTCGAGATCGCGCTTCAGGGCAGCAAGGATGTGGTGGGCGATGGCCGCATCTC
GGTGATCGACAATACGGTCGATCCGCAGACCGGCACGCTGATGGTGCGGGCCGTGTTCGAGAATGCGGACGAGCGCCTGT
GGCCCGGCACCCTTGGTGCCGTGTCGGTCACGCTGCGCATGGAGAGCGGCGTCGTCTCCGTTCCGGCGGAGGCGGTGCAG
AGCGGCCAGAGCGGCACCTTCGTCTTCGTGGTGGAAAATGACACTGCCCACGTGCGCCCGGTGACCATGGCCCGCACGGT
GGATGGCTATGCGGTCATCACCGCCGGCCTCAAGGGAGGTGAGGTCGTCGTGACGGACGGCCAGCTCTCGCTGCGCGAGG
GCAGCCGCGTCAGCGTAAAAGGCGCCGCCGCCTCGACGCCCGCGCCGGGAGCCTGA

Upstream 100 bases:

>100_bases
GTGCACGCGATACAAACCAGTCGCGGTACTATTTGGCAGAGTGTAGCCTCTCTAAATTCTGGAGCGTACGAGTGGCGGTC
CAAGAGGGACCGTCCTCCCT

Downstream 100 bases:

>100_bases
GCCATGTTCTCGGAGTTGTGCATCCGACGCCCGGTGATGACGACGCTGATGATGCTCTCCCTCATCATCGGCGGCCTCTT
CGCCTATCGCCTGCTGCCCG

Product: secretion protein HlyD precursor

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRWCMGGAKRTGRWRFYFLFFCLVAAGGAGWAWSQGLIGKGGGTAKAQSQPERRVAVVVATAQDRPMPVRIEALGTVEPQ
VTVTIRSRVASQVTSVAFEDGAVVNKGDLLFQLDPREVDAQILQARATLAKDKTQLEKALRDMERYSGLAARNTVSQVTL
DDARTTADAQKATVDQDEANLKALEVQRTYYDIRSPASGRLGVAAVRPGAVIRVDDTLATVRQIKPIYVAFGVPEHYLRD
IRAAQNDAKVEIALQGSKDVVGDGRISVIDNTVDPQTGTLMVRAVFENADERLWPGTLGAVSVTLRMESGVVSVPAEAVQ
SGQSGTFVFVVENDTAHVRPVTMARTVDGYAVITAGLKGGEVVVTDGQLSLREGSRVSVKGAAASTPAPGA

Sequences:

>Translated_391_residues
MRWCMGGAKRTGRWRFYFLFFCLVAAGGAGWAWSQGLIGKGGGTAKAQSQPERRVAVVVATAQDRPMPVRIEALGTVEPQ
VTVTIRSRVASQVTSVAFEDGAVVNKGDLLFQLDPREVDAQILQARATLAKDKTQLEKALRDMERYSGLAARNTVSQVTL
DDARTTADAQKATVDQDEANLKALEVQRTYYDIRSPASGRLGVAAVRPGAVIRVDDTLATVRQIKPIYVAFGVPEHYLRD
IRAAQNDAKVEIALQGSKDVVGDGRISVIDNTVDPQTGTLMVRAVFENADERLWPGTLGAVSVTLRMESGVVSVPAEAVQ
SGQSGTFVFVVENDTAHVRPVTMARTVDGYAVITAGLKGGEVVVTDGQLSLREGSRVSVKGAAASTPAPGA
>Mature_391_residues
MRWCMGGAKRTGRWRFYFLFFCLVAAGGAGWAWSQGLIGKGGGTAKAQSQPERRVAVVVATAQDRPMPVRIEALGTVEPQ
VTVTIRSRVASQVTSVAFEDGAVVNKGDLLFQLDPREVDAQILQARATLAKDKTQLEKALRDMERYSGLAARNTVSQVTL
DDARTTADAQKATVDQDEANLKALEVQRTYYDIRSPASGRLGVAAVRPGAVIRVDDTLATVRQIKPIYVAFGVPEHYLRD
IRAAQNDAKVEIALQGSKDVVGDGRISVIDNTVDPQTGTLMVRAVFENADERLWPGTLGAVSVTLRMESGVVSVPAEAVQ
SGQSGTFVFVVENDTAHVRPVTMARTVDGYAVITAGLKGGEVVVTDGQLSLREGSRVSVKGAAASTPAPGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=362, Percent_Identity=33.4254143646409, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789929, Length=316, Percent_Identity=28.4810126582279, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789665, Length=396, Percent_Identity=28.030303030303, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786668, Length=356, Percent_Identity=27.8089887640449, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87081951, Length=160, Percent_Identity=31.25, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41724; Mature: 41724

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWCMGGAKRTGRWRFYFLFFCLVAAGGAGWAWSQGLIGKGGGTAKAQSQPERRVAVVVA
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEE
TAQDRPMPVRIEALGTVEPQVTVTIRSRVASQVTSVAFEDGAVVNKGDLLFQLDPREVDA
ECCCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHHEECCCCEEECCCEEEEECCHHHHH
QILQARATLAKDKTQLEKALRDMERYSGLAARNTVSQVTLDDARTTADAQKATVDQDEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHEEEECCCCCCCCHHHCCCCCCCCC
LKALEVQRTYYDIRSPASGRLGVAAVRPGAVIRVDDTLATVRQIKPIYVAFGVPEHYLRD
EEEEEEEEHHHHCCCCCCCCEEEEEECCCEEEEECHHHHHHHHCCEEEEEECCCHHHHHH
IRAAQNDAKVEIALQGSKDVVGDGRISVIDNTVDPQTGTLMVRAVFENADERLWPGTLGA
HHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCE
VSVTLRMESGVVSVPAEAVQSGQSGTFVFVVENDTAHVRPVTMARTVDGYAVITAGLKGG
EEEEEEECCCEEECCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEECCCEEEEEECCCCC
EVVVTDGQLSLREGSRVSVKGAAASTPAPGA
EEEEECCEEEECCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MRWCMGGAKRTGRWRFYFLFFCLVAAGGAGWAWSQGLIGKGGGTAKAQSQPERRVAVVVA
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEE
TAQDRPMPVRIEALGTVEPQVTVTIRSRVASQVTSVAFEDGAVVNKGDLLFQLDPREVDA
ECCCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHHEECCCCEEECCCEEEEECCHHHHH
QILQARATLAKDKTQLEKALRDMERYSGLAARNTVSQVTLDDARTTADAQKATVDQDEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHEEEECCCCCCCCHHHCCCCCCCCC
LKALEVQRTYYDIRSPASGRLGVAAVRPGAVIRVDDTLATVRQIKPIYVAFGVPEHYLRD
EEEEEEEEHHHHCCCCCCCCEEEEEECCCEEEEECHHHHHHHHCCEEEEEECCCHHHHHH
IRAAQNDAKVEIALQGSKDVVGDGRISVIDNTVDPQTGTLMVRAVFENADERLWPGTLGA
HHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCE
VSVTLRMESGVVSVPAEAVQSGQSGTFVFVVENDTAHVRPVTMARTVDGYAVITAGLKGG
EEEEEEECCCEEECCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEECCCEEEEEECCCCC
EVVVTDGQLSLREGSRVSVKGAAASTPAPGA
EEEEECCEEEECCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA