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The map label for this gene is ybdL [H]

Identifier: 158423199

GI number: 158423199

Start: 1796066

End: 1797340

Strand: Direct

Name: ybdL [H]

Synonym: AZC_1575

Alternate gene names: 158423199

Gene position: 1796066-1797340 (Clockwise)

Preceding gene: 158423197

Following gene: 158423200

Centisome position: 33.45

GC content: 67.69

Gene sequence:

>1275_bases
TTGCGACGCTCAGGCCGGACAGCGGATGCCGCTCGGCAGGGGGCGCCGGAAGAACTGCCGAAGAGCGCCATGTCCGTCTC
CCTCGCCCCGCGTCCGCCCGTGCCCGCCGTCAGCCGGCTCAATTCCATCTATTCCGCCTTGCCCACCACCATCTTCGAGG
TGATGTCGGGTCTGGCCCGCACCCATCAGGCCGTTAACCTCGGACAGGGCTTTCCCGATGATCCGGGCCCGCTGGACGTG
CGCCAGAAGGCGGCGGACGCCGTGGTCGATGGCTGGAACCAGTATCCGCCCATGATGGGCCTTGCCGATCTGCGGCAGGC
GGCGGCGGTGCACTACAAGCATTGGCAGGGCCTCGACCTCGATCCCGAGAGCGAGGTGATGGTCACGTCGGGCGCCACCG
AGGCGCTGGCCGGCGCGCTCTTCTCGCTCATTGAGCCGGGCGACGAGGTGGTGCTGTTCCAGCCGCTCTATGACGCCTAT
CTGCCTCTCGTGCAGCGGGCGGGCGGCATTCCCCGGCTGGTGCGGCTGGAGCCGCCGTCCTGGCGCATCACCGCCGAGAA
GCTGGAGGCCGCCTTCTCGCCGCGCACCAAGGTGGTGTTGTTCAACAACCCGCAGAACCCGACGGGCATCGTGCATTCCC
GCGAGGAAATGCAGCTCATCGCCGATTTCTGCATCCGCTTCGACGTCATCGCCGTGTGCGACGAAGTGTGGGAGCACGTG
ATCTTCGACGGTCGCCGGCATCTGCCCATGATGGCGATCCCCGGCATGCGCGAGCGCACCGTGAAGATCTCGTCCGCCGG
CAAGATCTTCGGCATGACCGGCTGGAAGGTGGGCCTCGTCTTCGCCCAGCCTGAGCTGATGCGGGTGCTCGGCAAGGCGC
ACCAGTTCCTCACCTTCACCACCCCGCCGAACCTTCAGGCGGCGGTTGCCTATGGGCTCGGCAAGGAAGACGCCTATTTC
GAGGACATGCGCGCCGACCTCCAGCGCTCCCGCGACCGGCTGGCCAAGGGCCTGTCCGACCTCGGCTTCCCGGTGCTGCC
GAGCGCGGGCACCTATTTCCTTTCCGTGGACCTCGCGGCCATCGACCCGACGCTGGATGACGAGGCCTTCTGCCTCGATC
TCGTGAAGACCCACGGCGTGGCGGCCATTCCCGTCTCCGCCTTCTATGCGCAGGATGCGGTGCGCTCGGTGGTGCGCTTC
TGTTTCGCCAAGCGCGATGCCACGCTCGACGCCGCGCTGGAGCGCCTCGCCGGGGCGCTGCGCAACGGAAGGTAG

Upstream 100 bases:

>100_bases
GGGCGATCGCAAGGCGGCCCGGCGGACAATCCGGCGCTTCACCTCGCCGCCGAGTTGATCTAGAGCACGGACAACGGCCG
GCGTTTGCCGGCTCACTCCA

Downstream 100 bases:

>100_bases
GTCGTTTGTTCCGCTTTTGCTCCAGGTTGCTTGCCGCCTCGCGATAACGTTAGGTGAGGCTGGCATTTTTCGTTCCAGAA
TGAAGTGCACGCGATACAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRRSGRTADAARQGAPEELPKSAMSVSLAPRPPVPAVSRLNSIYSALPTTIFEVMSGLARTHQAVNLGQGFPDDPGPLDV
RQKAADAVVDGWNQYPPMMGLADLRQAAAVHYKHWQGLDLDPESEVMVTSGATEALAGALFSLIEPGDEVVLFQPLYDAY
LPLVQRAGGIPRLVRLEPPSWRITAEKLEAAFSPRTKVVLFNNPQNPTGIVHSREEMQLIADFCIRFDVIAVCDEVWEHV
IFDGRRHLPMMAIPGMRERTVKISSAGKIFGMTGWKVGLVFAQPELMRVLGKAHQFLTFTTPPNLQAAVAYGLGKEDAYF
EDMRADLQRSRDRLAKGLSDLGFPVLPSAGTYFLSVDLAAIDPTLDDEAFCLDLVKTHGVAAIPVSAFYAQDAVRSVVRF
CFAKRDATLDAALERLAGALRNGR

Sequences:

>Translated_424_residues
MRRSGRTADAARQGAPEELPKSAMSVSLAPRPPVPAVSRLNSIYSALPTTIFEVMSGLARTHQAVNLGQGFPDDPGPLDV
RQKAADAVVDGWNQYPPMMGLADLRQAAAVHYKHWQGLDLDPESEVMVTSGATEALAGALFSLIEPGDEVVLFQPLYDAY
LPLVQRAGGIPRLVRLEPPSWRITAEKLEAAFSPRTKVVLFNNPQNPTGIVHSREEMQLIADFCIRFDVIAVCDEVWEHV
IFDGRRHLPMMAIPGMRERTVKISSAGKIFGMTGWKVGLVFAQPELMRVLGKAHQFLTFTTPPNLQAAVAYGLGKEDAYF
EDMRADLQRSRDRLAKGLSDLGFPVLPSAGTYFLSVDLAAIDPTLDDEAFCLDLVKTHGVAAIPVSAFYAQDAVRSVVRF
CFAKRDATLDAALERLAGALRNGR
>Mature_424_residues
MRRSGRTADAARQGAPEELPKSAMSVSLAPRPPVPAVSRLNSIYSALPTTIFEVMSGLARTHQAVNLGQGFPDDPGPLDV
RQKAADAVVDGWNQYPPMMGLADLRQAAAVHYKHWQGLDLDPESEVMVTSGATEALAGALFSLIEPGDEVVLFQPLYDAY
LPLVQRAGGIPRLVRLEPPSWRITAEKLEAAFSPRTKVVLFNNPQNPTGIVHSREEMQLIADFCIRFDVIAVCDEVWEHV
IFDGRRHLPMMAIPGMRERTVKISSAGKIFGMTGWKVGLVFAQPELMRVLGKAHQFLTFTTPPNLQAAVAYGLGKEDAYF
EDMRADLQRSRDRLAKGLSDLGFPVLPSAGTYFLSVDLAAIDPTLDDEAFCLDLVKTHGVAAIPVSAFYAQDAVRSVVRF
CFAKRDATLDAALERLAGALRNGR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=399, Percent_Identity=35.3383458646617, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI56713256, Length=399, Percent_Identity=35.3383458646617, Blast_Score=255, Evalue=6e-68,
Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=37.4683544303797, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=37.4683544303797, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI169881281, Length=395, Percent_Identity=33.1645569620253, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI4507369, Length=345, Percent_Identity=25.5072463768116, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1786816, Length=370, Percent_Identity=41.3513513513514, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1788722, Length=314, Percent_Identity=26.7515923566879, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788627, Length=186, Percent_Identity=24.7311827956989, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787909, Length=291, Percent_Identity=25.085910652921, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787710, Length=328, Percent_Identity=26.8292682926829, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=427, Percent_Identity=33.9578454332553, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71994476, Length=427, Percent_Identity=33.9578454332553, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17567369, Length=411, Percent_Identity=31.3868613138686, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17567663, Length=350, Percent_Identity=20.2857142857143, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=32.5581395348837, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI28573069, Length=399, Percent_Identity=35.0877192982456, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24646114, Length=399, Percent_Identity=35.0877192982456, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI28573067, Length=399, Percent_Identity=35.0877192982456, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI28573065, Length=399, Percent_Identity=35.0877192982456, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI18859735, Length=353, Percent_Identity=25.7790368271955, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 46353; Mature: 46353

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSGRTADAARQGAPEELPKSAMSVSLAPRPPVPAVSRLNSIYSALPTTIFEVMSGLAR
CCCCCCCHHHHHCCCCHHHCHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
THQAVNLGQGFPDDPGPLDVRQKAADAVVDGWNQYPPMMGLADLRQAAAVHYKHWQGLDL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
DPESEVMVTSGATEALAGALFSLIEPGDEVVLFQPLYDAYLPLVQRAGGIPRLVRLEPPS
CCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEECCCC
WRITAEKLEAAFSPRTKVVLFNNPQNPTGIVHSREEMQLIADFCIRFDVIAVCDEVWEHV
CEEEHHHHHHHCCCCEEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFDGRRHLPMMAIPGMRERTVKISSAGKIFGMTGWKVGLVFAQPELMRVLGKAHQFLTFT
HHCCCCCCCEEECCCCCCCEEEEECCCCEEEECCCEEEEEECCHHHHHHHHHHHHEEEEC
TPPNLQAAVAYGLGKEDAYFEDMRADLQRSRDRLAKGLSDLGFPVLPSAGTYFLSVDLAA
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
IDPTLDDEAFCLDLVKTHGVAAIPVSAFYAQDAVRSVVRFCFAKRDATLDAALERLAGAL
ECCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RNGR
HCCC
>Mature Secondary Structure
MRRSGRTADAARQGAPEELPKSAMSVSLAPRPPVPAVSRLNSIYSALPTTIFEVMSGLAR
CCCCCCCHHHHHCCCCHHHCHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
THQAVNLGQGFPDDPGPLDVRQKAADAVVDGWNQYPPMMGLADLRQAAAVHYKHWQGLDL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
DPESEVMVTSGATEALAGALFSLIEPGDEVVLFQPLYDAYLPLVQRAGGIPRLVRLEPPS
CCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEECCCC
WRITAEKLEAAFSPRTKVVLFNNPQNPTGIVHSREEMQLIADFCIRFDVIAVCDEVWEHV
CEEEHHHHHHHCCCCEEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFDGRRHLPMMAIPGMRERTVKISSAGKIFGMTGWKVGLVFAQPELMRVLGKAHQFLTFT
HHCCCCCCCEEECCCCCCCEEEEECCCCEEEECCCEEEEEECCHHHHHHHHHHHHEEEEC
TPPNLQAAVAYGLGKEDAYFEDMRADLQRSRDRLAKGLSDLGFPVLPSAGTYFLSVDLAA
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
IDPTLDDEAFCLDLVKTHGVAAIPVSAFYAQDAVRSVVRFCFAKRDATLDAALERLAGAL
ECCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RNGR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]