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The map label for this gene is vllY [H]

Identifier: 158423078

GI number: 158423078

Start: 1653945

End: 1655864

Strand: Direct

Name: vllY [H]

Synonym: AZC_1454

Alternate gene names: 158423078

Gene position: 1653945-1655864 (Clockwise)

Preceding gene: 158423077

Following gene: 158423079

Centisome position: 30.8

GC content: 67.92

Gene sequence:

>1920_bases
ATGATCCCGTCCATCGCCACGGTCTGCGTTTCGGGAACCCTCGTGGAGAAGCTGGAGGCCATCGCCGCCGCCGGCTTTCC
GGCGGTGGAAATCTTCGAGAACGATCTCATCGCCTTTCCCGGCTCGCCGGCCGATGTGCGCCGCATCTGCGCCGATCTCG
GCCTCGCCATCGTCACCTGCCAGCCGTTCCGCGATTTCGAGGGCATGCCGCAGGCGCGCCGCCAGCGCACCTTCGACCGG
GCCGAGCGCAAGTTCGACCTGCTTGAGGAACTCGGCTGCGACCTGCTCTTCGTCTGCTCCAGCGTCTCGCCGGAGGCGGA
GAGCGGCATCGATCGGCTGGCTGCGGATTTCGTGGAACTGGGCGAACGGGCGGCCCGTCGCGGCCTGCGGGTCGGCTATG
AGGCGCTCGCCTGGGGCCGGCACGTCTGGGACTATCGCGACGCCTGGGAAATCGTGCGCCGCGCGAACCAGCCCAACGTG
GGCGTCGTGCTGGACAGCTTCCACATTCTCGCGCGGGGGCTGGAGCTGACCTCCATCGGCCGCATTCCCCGTGACCGCAT
CGCCATGGTGCAGATGGCCGATGCGCCGCTGCTTCAGCTCGATCCACTCTCCTGGAGCCGCCACTGGCGTTGCCTGCCGG
GGCAGGGCGATCTCAATCTCTCCGGCTTCATGGATGCACTTGCGGCCACCGGCTATGAGGGCGTGCTGTCGCTGGAAATC
TTCAACGACCGTTTCCGCGCCGGCTCGGCCCGCTCCGTGGCGCTGGATGGGCACCGCTCGCTGATCTGGCTGCTGGACGA
AACCGCGCGCCGGCTCGGGCGGCCTCTCAAGGGCGCTGTACCCATGCCGCCGCCGGGCCCGGTGGAGGCGGTGGAATTCA
TCGAATTTGCGGTCTCCGAGACCGGCCGTCCGGCGCTTGAGGGCGTGCTGGCGGCACTCGGCTTCAGCCGCACGGGGCGG
CACCGTTCCAAGGATGTGGCCCTCTGGAGCCAGGGCGACATCCGTATCGTCCTCAACAGCGATGCGGAGGGCTTCGCCCA
CAGCTACCAGATCACCCACGGCACCTCCGTCTGCGCGCTCGCCCTGCGCGTTCCGGATGCGCGCGCCGCCACTGAGCGGG
CGCGGGCGCTGCGGGACGTGCCCTATGCGGGCGCCATCGGGCCGGGGGAACTGGACATTCCGGCCGTGCGCGGTCTGGGG
GGCAGCCTGCTCTACTTCCTCGATCAGGCTTCGGCGCTGGGCGGCTGGTCTGCCGTGGATTTCGAGCCGGTGGCGGCGAA
CGTGGCGCCGACCGGGCTCACCCACGTCGATCACATCTCCCAGAGCATGCAATATGAGGAAATGCTCACCTGGCTGCTCT
TCTATTCCTCGCTTTTCGAGACGCGGAAGACGCCGAGCCAGGCGGTGATCGATCCCGGCGGCGTGGTCCAGAGCCAGGTG
GTGGAGAGCGGGCTAGAGGGGGGCACGGGGCAGGGGCTGCGCCTCATCCTCAATGGCTCGCAAAGCCACCGCACGCTCTC
TGCGCGTTTCGTTCACGAGCTTTTCGGCTCGGGCGTGCAGCACATTGCCTTCGCCACCACCGACATCGAGGCGACCGTCC
GCCAGCTTGTCGCGAACGGTGTCGCCATGCTGCCGATCCCGGAGAATTATTACGATGATCTCGAAGCGCGGTCCGACCTC
CCGCCCGAGGCCATCGACCGCATGAAGGCGCTGAACATCCTCTATGACCGGGATGCCTCCGGCGAATTCCGTCAGGCCTA
TACGACGCTGCTGGACGGCGGTCTGTTTTTCGAGATCATCCAACGGGACGGCTATGAAGGCTATGGGGCGGCGAATGCCG
GCATCCGGCTGGCGGCGCAGGCCCGCCTCCAGCCACTGGAAGCGCCGGTGTTCGGGGAGGCCGGCGCCGCGCCCGAATGA

Upstream 100 bases:

>100_bases
TTCGAGCAGATTCCGGCCTATTTCGAATTCTTCGGCCTGCCGCCCACGACGCCGGAGGCCCTGAGGGCCGCCGCGCAGCT
CGATTGAGAAGGAGCCCGCC

Downstream 100 bases:

>100_bases
GCGCGCGGGGCGGTCGTATTCATGAGCGGGCCGTCTGAGTTTATGCCGTTCGAGCGGCTAATCTCATCGCCCGCTTTAGG
ATAGCGTGCCGGCACCGACC

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: homogentisate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MIPSIATVCVSGTLVEKLEAIAAAGFPAVEIFENDLIAFPGSPADVRRICADLGLAIVTCQPFRDFEGMPQARRQRTFDR
AERKFDLLEELGCDLLFVCSSVSPEAESGIDRLAADFVELGERAARRGLRVGYEALAWGRHVWDYRDAWEIVRRANQPNV
GVVLDSFHILARGLELTSIGRIPRDRIAMVQMADAPLLQLDPLSWSRHWRCLPGQGDLNLSGFMDALAATGYEGVLSLEI
FNDRFRAGSARSVALDGHRSLIWLLDETARRLGRPLKGAVPMPPPGPVEAVEFIEFAVSETGRPALEGVLAALGFSRTGR
HRSKDVALWSQGDIRIVLNSDAEGFAHSYQITHGTSVCALALRVPDARAATERARALRDVPYAGAIGPGELDIPAVRGLG
GSLLYFLDQASALGGWSAVDFEPVAANVAPTGLTHVDHISQSMQYEEMLTWLLFYSSLFETRKTPSQAVIDPGGVVQSQV
VESGLEGGTGQGLRLILNGSQSHRTLSARFVHELFGSGVQHIAFATTDIEATVRQLVANGVAMLPIPENYYDDLEARSDL
PPEAIDRMKALNILYDRDASGEFRQAYTTLLDGGLFFEIIQRDGYEGYGAANAGIRLAAQARLQPLEAPVFGEAGAAPE

Sequences:

>Translated_639_residues
MIPSIATVCVSGTLVEKLEAIAAAGFPAVEIFENDLIAFPGSPADVRRICADLGLAIVTCQPFRDFEGMPQARRQRTFDR
AERKFDLLEELGCDLLFVCSSVSPEAESGIDRLAADFVELGERAARRGLRVGYEALAWGRHVWDYRDAWEIVRRANQPNV
GVVLDSFHILARGLELTSIGRIPRDRIAMVQMADAPLLQLDPLSWSRHWRCLPGQGDLNLSGFMDALAATGYEGVLSLEI
FNDRFRAGSARSVALDGHRSLIWLLDETARRLGRPLKGAVPMPPPGPVEAVEFIEFAVSETGRPALEGVLAALGFSRTGR
HRSKDVALWSQGDIRIVLNSDAEGFAHSYQITHGTSVCALALRVPDARAATERARALRDVPYAGAIGPGELDIPAVRGLG
GSLLYFLDQASALGGWSAVDFEPVAANVAPTGLTHVDHISQSMQYEEMLTWLLFYSSLFETRKTPSQAVIDPGGVVQSQV
VESGLEGGTGQGLRLILNGSQSHRTLSARFVHELFGSGVQHIAFATTDIEATVRQLVANGVAMLPIPENYYDDLEARSDL
PPEAIDRMKALNILYDRDASGEFRQAYTTLLDGGLFFEIIQRDGYEGYGAANAGIRLAAQARLQPLEAPVFGEAGAAPE
>Mature_639_residues
MIPSIATVCVSGTLVEKLEAIAAAGFPAVEIFENDLIAFPGSPADVRRICADLGLAIVTCQPFRDFEGMPQARRQRTFDR
AERKFDLLEELGCDLLFVCSSVSPEAESGIDRLAADFVELGERAARRGLRVGYEALAWGRHVWDYRDAWEIVRRANQPNV
GVVLDSFHILARGLELTSIGRIPRDRIAMVQMADAPLLQLDPLSWSRHWRCLPGQGDLNLSGFMDALAATGYEGVLSLEI
FNDRFRAGSARSVALDGHRSLIWLLDETARRLGRPLKGAVPMPPPGPVEAVEFIEFAVSETGRPALEGVLAALGFSRTGR
HRSKDVALWSQGDIRIVLNSDAEGFAHSYQITHGTSVCALALRVPDARAATERARALRDVPYAGAIGPGELDIPAVRGLG
GSLLYFLDQASALGGWSAVDFEPVAANVAPTGLTHVDHISQSMQYEEMLTWLLFYSSLFETRKTPSQAVIDPGGVVQSQV
VESGLEGGTGQGLRLILNGSQSHRTLSARFVHELFGSGVQHIAFATTDIEATVRQLVANGVAMLPIPENYYDDLEARSDL
PPEAIDRMKALNILYDRDASGEFRQAYTTLLDGGLFFEIIQRDGYEGYGAANAGIRLAAQARLQPLEAPVFGEAGAAPE

Specific function: Unknown

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI4504477, Length=303, Percent_Identity=25.0825082508251, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI285002264, Length=303, Percent_Identity=24.7524752475248, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555220, Length=103, Percent_Identity=43.6893203883495, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17550752, Length=380, Percent_Identity=24.2105263157895, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356105, Length=286, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24667510, Length=286, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 1.13.11.27

Molecular weight: Translated: 69363; Mature: 69363

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSIATVCVSGTLVEKLEAIAAAGFPAVEIFENDLIAFPGSPADVRRICADLGLAIVTC
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCHHHHHHHHHCCEEEEEE
QPFRDFEGMPQARRQRTFDRAERKFDLLEELGCDLLFVCSSVSPEAESGIDRLAADFVEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
GERAARRGLRVGYEALAWGRHVWDYRDAWEIVRRANQPNVGVVLDSFHILARGLELTSIG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCHHHHC
RIPRDRIAMVQMADAPLLQLDPLSWSRHWRCLPGQGDLNLSGFMDALAATGYEGVLSLEI
CCCHHHHHHEEECCCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEE
FNDRFRAGSARSVALDGHRSLIWLLDETARRLGRPLKGAVPMPPPGPVEAVEFIEFAVSE
ECCHHCCCCCCEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHC
TGRPALEGVLAALGFSRTGRHRSKDVALWSQGDIRIVLNSDAEGFAHSYQITHGTSVCAL
CCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEECCCCEEEE
ALRVPDARAATERARALRDVPYAGAIGPGELDIPAVRGLGGSLLYFLDQASALGGWSAVD
EEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCC
FEPVAANVAPTGLTHVDHISQSMQYEEMLTWLLFYSSLFETRKTPSQAVIDPGGVVQSQV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHH
VESGLEGGTGQGLRLILNGSQSHRTLSARFVHELFGSGVQHIAFATTDIEATVRQLVANG
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHEEEECHHHHHHHHHHHCC
VAMLPIPENYYDDLEARSDLPPEAIDRMKALNILYDRDASGEFRQAYTTLLDGGLFFEII
EEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHH
QRDGYEGYGAANAGIRLAAQARLQPLEAPVFGEAGAAPE
HHCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPSIATVCVSGTLVEKLEAIAAAGFPAVEIFENDLIAFPGSPADVRRICADLGLAIVTC
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCHHHHHHHHHCCEEEEEE
QPFRDFEGMPQARRQRTFDRAERKFDLLEELGCDLLFVCSSVSPEAESGIDRLAADFVEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
GERAARRGLRVGYEALAWGRHVWDYRDAWEIVRRANQPNVGVVLDSFHILARGLELTSIG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCHHHHC
RIPRDRIAMVQMADAPLLQLDPLSWSRHWRCLPGQGDLNLSGFMDALAATGYEGVLSLEI
CCCHHHHHHEEECCCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEE
FNDRFRAGSARSVALDGHRSLIWLLDETARRLGRPLKGAVPMPPPGPVEAVEFIEFAVSE
ECCHHCCCCCCEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHC
TGRPALEGVLAALGFSRTGRHRSKDVALWSQGDIRIVLNSDAEGFAHSYQITHGTSVCAL
CCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEECCCCEEEE
ALRVPDARAATERARALRDVPYAGAIGPGELDIPAVRGLGGSLLYFLDQASALGGWSAVD
EEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCC
FEPVAANVAPTGLTHVDHISQSMQYEEMLTWLLFYSSLFETRKTPSQAVIDPGGVVQSQV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHH
VESGLEGGTGQGLRLILNGSQSHRTLSARFVHELFGSGVQHIAFATTDIEATVRQLVANG
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHEEEECHHHHHHHHHHHCC
VAMLPIPENYYDDLEARSDLPPEAIDRMKALNILYDRDASGEFRQAYTTLLDGGLFFEII
EEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHH
QRDGYEGYGAANAGIRLAAQARLQPLEAPVFGEAGAAPE
HHCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxyphenylpyruvate; O2

Specific reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA