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The map label for this gene is aroE [H]

Identifier: 158423077

GI number: 158423077

Start: 1653101

End: 1653931

Strand: Direct

Name: aroE [H]

Synonym: AZC_1453

Alternate gene names: 158423077

Gene position: 1653101-1653931 (Clockwise)

Preceding gene: 158423076

Following gene: 158423078

Centisome position: 30.79

GC content: 68.23

Gene sequence:

>831_bases
ATGATCAGTGGAACAACAAAGCTCATCGGCCACATCGGCTTTCCGACCGAGAGCTTCAAGTCGCCGATGATCTACAATCC
CTATTTCGAGCGCGAGGGGATCGACGCGGTCGTCGTGCCCATGGGCTGCGAGGTCCCCGATTACCCGTCCTTCCTCAAGC
TCTTCTTCCGCCTGTCCAATGCGCTCGGCACGCTCATCACCATGCCGCACAAGGTGACGACCCTCTCGCTGGTGGACGCG
GCCTCGCCGACCGCGGCCATCGCCGGGGCCTGCAATGCCGTGCGCCGGCGCGAAGATGGCCGCCTTGAGGGCGACCTGTT
CGACGGAGAGGGCTTCGTGCGCGGGATGCGCCGGAAGGGGCGGGTGATCGAGGGCACCCATGCCCTCGTGGTGGGAGCCG
GCGGCGTCGGCTCGGCCATCGCAGCGTCCCTCGCCCGCGCCGGCGTCGCCCGCATCACGCTCTTCGACAGCCATCCTGAG
GCCGCCCGGCAATTGGCCGAGCGGCTGAAGCGCCATTATCCGGCCCTTGAGGTTGAGGTGGGCGCGAACGATCCGGCCGG
TTGCGACATCGTGGTGAACGCGACGCCCCTCGGCATGCGCGCGGGCGATCCGCTTCCGGTGGAGGTGGAGCGCATTGCGC
CCTCGGCCTTCGTCGGGGAGGTGGTGATGACCCACGAGATCACGCCCTTCCTCGCCGCCGTGCGGGCGCGCGGCTGCGCC
TTCCAGGTCGGCACCGACATGCTGTTCGAGCAGATTCCGGCCTATTTCGAATTCTTCGGCCTGCCGCCCACGACGCCGGA
GGCCCTGAGGGCCGCCGCGCAGCTCGATTGA

Upstream 100 bases:

>100_bases
CTCGCACTGAGGCCGACAGGATGGGGAAGGGCGGGTGCGCCCTTCCCGCTCTCGCGCCGGGGGCAGGCCGCGCCGTGGAT
GGAACAGGTCGGGGCATGAA

Downstream 100 bases:

>100_bases
GAAGGAGCCCGCCATGATCCCGTCCATCGCCACGGTCTGCGTTTCGGGAACCCTCGTGGAGAAGCTGGAGGCCATCGCCG
CCGCCGGCTTTCCGGCGGTG

Product: shikimate dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MISGTTKLIGHIGFPTESFKSPMIYNPYFEREGIDAVVVPMGCEVPDYPSFLKLFFRLSNALGTLITMPHKVTTLSLVDA
ASPTAAIAGACNAVRRREDGRLEGDLFDGEGFVRGMRRKGRVIEGTHALVVGAGGVGSAIAASLARAGVARITLFDSHPE
AARQLAERLKRHYPALEVEVGANDPAGCDIVVNATPLGMRAGDPLPVEVERIAPSAFVGEVVMTHEITPFLAAVRARGCA
FQVGTDMLFEQIPAYFEFFGLPPTTPEALRAAAQLD

Sequences:

>Translated_276_residues
MISGTTKLIGHIGFPTESFKSPMIYNPYFEREGIDAVVVPMGCEVPDYPSFLKLFFRLSNALGTLITMPHKVTTLSLVDA
ASPTAAIAGACNAVRRREDGRLEGDLFDGEGFVRGMRRKGRVIEGTHALVVGAGGVGSAIAASLARAGVARITLFDSHPE
AARQLAERLKRHYPALEVEVGANDPAGCDIVVNATPLGMRAGDPLPVEVERIAPSAFVGEVVMTHEITPFLAAVRARGCA
FQVGTDMLFEQIPAYFEFFGLPPTTPEALRAAAQLD
>Mature_276_residues
MISGTTKLIGHIGFPTESFKSPMIYNPYFEREGIDAVVVPMGCEVPDYPSFLKLFFRLSNALGTLITMPHKVTTLSLVDA
ASPTAAIAGACNAVRRREDGRLEGDLFDGEGFVRGMRRKGRVIEGTHALVVGAGGVGSAIAASLARAGVARITLFDSHPE
AARQLAERLKRHYPALEVEVGANDPAGCDIVVNATPLGMRAGDPLPVEVERIAPSAFVGEVVMTHEITPFLAAVRARGCA
FQVGTDMLFEQIPAYFEFFGLPPTTPEALRAAAQLD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=270, Percent_Identity=26.6666666666667, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789675, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29467; Mature: 29467

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGTTKLIGHIGFPTESFKSPMIYNPYFEREGIDAVVVPMGCEVPDYPSFLKLFFRLSN
CCCCHHHHHEECCCCHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ALGTLITMPHKVTTLSLVDAASPTAAIAGACNAVRRREDGRLEGDLFDGEGFVRGMRRKG
HHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCC
RVIEGTHALVVGAGGVGSAIAASLARAGVARITLFDSHPEAARQLAERLKRHYPALEVEV
CEEECCEEEEEECCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEE
GANDPAGCDIVVNATPLGMRAGDPLPVEVERIAPSAFVGEVVMTHEITPFLAAVRARGCA
CCCCCCCCEEEEECCCCCCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCE
FQVGTDMLFEQIPAYFEFFGLPPTTPEALRAAAQLD
EEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MISGTTKLIGHIGFPTESFKSPMIYNPYFEREGIDAVVVPMGCEVPDYPSFLKLFFRLSN
CCCCHHHHHEECCCCHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ALGTLITMPHKVTTLSLVDAASPTAAIAGACNAVRRREDGRLEGDLFDGEGFVRGMRRKG
HHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCC
RVIEGTHALVVGAGGVGSAIAASLARAGVARITLFDSHPEAARQLAERLKRHYPALEVEV
CEEECCEEEEEECCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEE
GANDPAGCDIVVNATPLGMRAGDPLPVEVERIAPSAFVGEVVMTHEITPFLAAVRARGCA
CCCCCCCCEEEEECCCCCCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCE
FQVGTDMLFEQIPAYFEFFGLPPTTPEALRAAAQLD
EEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA