Click here to switch to the map view.

The map label for this gene is pcoA [H]

Identifier: 158423058

GI number: 158423058

Start: 1634633

End: 1636189

Strand: Direct

Name: pcoA [H]

Synonym: AZC_1434

Alternate gene names: 158423058

Gene position: 1634633-1636189 (Clockwise)

Preceding gene: 158423057

Following gene: 158423069

Centisome position: 30.44

GC content: 69.11

Gene sequence:

>1557_bases
ATGACCCAGCCCTTTTCCGCCTCCCCCCTCTCGCGCCGCGCCGTGCTGGCGGGCGGCGTCGCAGCAGGAGCGCTTGCCCT
CTCAGGGCGTTGGAACGTGGCGCGTGCGGCGCCGCTGATCACGGTGGAGAGCGTGTCACTCGACGTGAATGGCAAGGCGG
CCAAGGTCTATGCCATTCAGGGGCCTGCGGGGGAGGGCGTGTTCGCGAAGGAGGGCGACCGCTTCGCCGGCGCCATCCTC
AATGCGGCTCCCGAGCCGGCGGTCATGCACTGGCACGGCCAGATCTTCGCGCCGCCGGATCAGGACCGCGCCCGTCCCGA
TGGCGGCGCGCTGGCCTCAGGGGCGAGCGATCAGGTGGACTTTCCGCTGACCCCCGGCACCCACTGGATGCACTCCCACA
CGCTCTCCGAACAGCAGCTTCTCGCGGCTCCGCTGGTGACCCGCGAGGCCGATGCCGGGGACGTGCAGGATGTGGTGCTG
ATGCTCCACGATTTCTCCTTCCGCACGCCGGAGGAAATCCTGGCCGGCCTCGGCGGCACAAACGGCCATGGCGCCCACGG
CGGGCACACGACGGGCGGGACCGGCGGTGCGGCGACGGGGGGCACGTCCGGCGGCGGCATGTCCATCGCCGGCATGGATC
ATTCCGGCCATAACATGGGGTCTATGGGCGGCATGGGCGCGATGGCCTCTGGCGGAGCCATGAACCATTCGGGGCATTCC
ATGCCCGGTGGGGCCATGGGCGGAAGCGGCATGGTTCATGCCAATGACGTGGATTACGACGCCTTCCTTGCCAACCGCCG
TACGCTCGCCGATCCGCAGGTGGTGCCCGTGGAGAAGGGAGGGCGTGTTCGTCTGCGCATCATCAACGGTGGCACGGCCA
GCGCCTTCTTCATTTCCGTCCCGGGCCTGAAGCCCAGCTGCATCGCGGTCGACGGCACGCCGTGCGTTCCCCTGGAGGCA
GCGCTGTTCCCGCTGGCCCAAGGGCAGCGCATCGACTTGCTGGTGGACGTGCCGGCCAGCGGTGGCGCGTTCCCCGTGCT
TGCGCAGGTGGAGGCGTCGCCGCGCCGCACGGGGCTCGTGCTCGCGACGCCGGGAGCCTCCGTGGCCCGGATCACGGACA
CGGCCGACGCGGCGCAGGGCCTGCTGTCTCTGGAACTGGAGGGCCGTCTGTCGGCGGCAATGCCGCTCGCGGCGCGCAAG
CCGGACAAGAGCTTCTCCCTTCTGCTTGGAGAGCAGCCGGGCTATCGCTGGACCATCAACGGTGCGGTGTATGGGGAGGC
CCCGCCCTTTGTGGTGAACCAGGGCGAGCGGGTCGAGATGACCTTCATGAACCCCACCAGCATGAACCATCCCATGCATC
TGCACGGCCACCATTTTCAGGTGGTCGGCATCGGCACGCGCCGCTTCTCCGGGGCGATGCGCGACACGGTGAACGTTCCG
CCGCGCACCCCGGTCACCATCGCGTTCGATGCGGGGCCGAAGGGGGACTGGTTCCTCCACTGCCATCACCTCTACCACAT
GGCGACTGGCATGATGGGCGTGGTGCGGGTGGCTTAG

Upstream 100 bases:

>100_bases
TTTCTCGCTTCCTATGGCCCCATGCTCTGCCGCCGCTAGAGCATGGCCAAGATCAGATCGGCGCGGACGAAGGCTGCCGC
TCGCGCCCGGAGAGACGACG

Downstream 100 bases:

>100_bases
CCGCTCGGCGCAGGCCTCGTCCTTCGGCACAGGGCCTCAGTGTGTGGCTGGCTTGTGCGGCGGGCGGGCGTTGCTGACCT
TCGGGTCCGGCGCCTTTCCG

Product: twin-arginine translocation pathway signal precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MTQPFSASPLSRRAVLAGGVAAGALALSGRWNVARAAPLITVESVSLDVNGKAAKVYAIQGPAGEGVFAKEGDRFAGAIL
NAAPEPAVMHWHGQIFAPPDQDRARPDGGALASGASDQVDFPLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVL
MLHDFSFRTPEEILAGLGGTNGHGAHGGHTTGGTGGAATGGTSGGGMSIAGMDHSGHNMGSMGGMGAMASGGAMNHSGHS
MPGGAMGGSGMVHANDVDYDAFLANRRTLADPQVVPVEKGGRVRLRIINGGTASAFFISVPGLKPSCIAVDGTPCVPLEA
ALFPLAQGQRIDLLVDVPASGGAFPVLAQVEASPRRTGLVLATPGASVARITDTADAAQGLLSLELEGRLSAAMPLAARK
PDKSFSLLLGEQPGYRWTINGAVYGEAPPFVVNQGERVEMTFMNPTSMNHPMHLHGHHFQVVGIGTRRFSGAMRDTVNVP
PRTPVTIAFDAGPKGDWFLHCHHLYHMATGMMGVVRVA

Sequences:

>Translated_518_residues
MTQPFSASPLSRRAVLAGGVAAGALALSGRWNVARAAPLITVESVSLDVNGKAAKVYAIQGPAGEGVFAKEGDRFAGAIL
NAAPEPAVMHWHGQIFAPPDQDRARPDGGALASGASDQVDFPLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVL
MLHDFSFRTPEEILAGLGGTNGHGAHGGHTTGGTGGAATGGTSGGGMSIAGMDHSGHNMGSMGGMGAMASGGAMNHSGHS
MPGGAMGGSGMVHANDVDYDAFLANRRTLADPQVVPVEKGGRVRLRIINGGTASAFFISVPGLKPSCIAVDGTPCVPLEA
ALFPLAQGQRIDLLVDVPASGGAFPVLAQVEASPRRTGLVLATPGASVARITDTADAAQGLLSLELEGRLSAAMPLAARK
PDKSFSLLLGEQPGYRWTINGAVYGEAPPFVVNQGERVEMTFMNPTSMNHPMHLHGHHFQVVGIGTRRFSGAMRDTVNVP
PRTPVTIAFDAGPKGDWFLHCHHLYHMATGMMGVVRVA
>Mature_517_residues
TQPFSASPLSRRAVLAGGVAAGALALSGRWNVARAAPLITVESVSLDVNGKAAKVYAIQGPAGEGVFAKEGDRFAGAILN
AAPEPAVMHWHGQIFAPPDQDRARPDGGALASGASDQVDFPLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVLM
LHDFSFRTPEEILAGLGGTNGHGAHGGHTTGGTGGAATGGTSGGGMSIAGMDHSGHNMGSMGGMGAMASGGAMNHSGHSM
PGGAMGGSGMVHANDVDYDAFLANRRTLADPQVVPVEKGGRVRLRIINGGTASAFFISVPGLKPSCIAVDGTPCVPLEAA
LFPLAQGQRIDLLVDVPASGGAFPVLAQVEASPRRTGLVLATPGASVARITDTADAAQGLLSLELEGRLSAAMPLAARKP
DKSFSLLLGEQPGYRWTINGAVYGEAPPFVVNQGERVEMTFMNPTSMNHPMHLHGHHFQVVGIGTRRFSGAMRDTVNVPP
RTPVTIAFDAGPKGDWFLHCHHLYHMATGMMGVVRVA

Specific function: Required for the copper-inducible expression of copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 53445; Mature: 53314

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPFSASPLSRRAVLAGGVAAGALALSGRWNVARAAPLITVESVSLDVNGKAAKVYAIQ
CCCCCCCCCCCCCEEEECCCEECEEEECCCCCHHHCCEEEEEEEEEEEECCCEEEEEEEE
GPAGEGVFAKEGDRFAGAILNAAPEPAVMHWHGQIFAPPDQDRARPDGGALASGASDQVD
CCCCCCCEECCCCCHHHHHHCCCCCCEEEEECCEEECCCCHHHCCCCCCCCCCCCCCCEE
FPLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVLMLHDFSFRTPEEILAGLGGT
CCCCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCC
NGHGAHGGHTTGGTGGAATGGTSGGGMSIAGMDHSGHNMGSMGGMGAMASGGAMNHSGHS
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MPGGAMGGSGMVHANDVDYDAFLANRRTLADPQVVPVEKGGRVRLRIINGGTASAFFISV
CCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCCEEEECCCCEEEEEEEECCCCEEEEEEC
PGLKPSCIAVDGTPCVPLEAALFPLAQGQRIDLLVDVPASGGAFPVLAQVEASPRRTGLV
CCCCCCEEEECCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCEEE
LATPGASVARITDTADAAQGLLSLELEGRLSAAMPLAARKPDKSFSLLLGEQPGYRWTIN
EECCCCCEEEEECCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEC
GAVYGEAPPFVVNQGERVEMTFMNPTSMNHPMHLHGHHFQVVGIGTRRFSGAMRDTVNVP
CEEECCCCCEEECCCCEEEEEEECCCCCCCCEEECCCEEEEEEECHHHHCCHHHCCCCCC
PRTPVTIAFDAGPKGDWFLHCHHLYHMATGMMGVVRVA
CCCCEEEEECCCCCCCEEEEHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
TQPFSASPLSRRAVLAGGVAAGALALSGRWNVARAAPLITVESVSLDVNGKAAKVYAIQ
CCCCCCCCCCCCEEEECCCEECEEEECCCCCHHHCCEEEEEEEEEEEECCCEEEEEEEE
GPAGEGVFAKEGDRFAGAILNAAPEPAVMHWHGQIFAPPDQDRARPDGGALASGASDQVD
CCCCCCCEECCCCCHHHHHHCCCCCCEEEEECCEEECCCCHHHCCCCCCCCCCCCCCCEE
FPLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVLMLHDFSFRTPEEILAGLGGT
CCCCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCC
NGHGAHGGHTTGGTGGAATGGTSGGGMSIAGMDHSGHNMGSMGGMGAMASGGAMNHSGHS
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MPGGAMGGSGMVHANDVDYDAFLANRRTLADPQVVPVEKGGRVRLRIINGGTASAFFISV
CCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCCEEEECCCCEEEEEEEECCCCEEEEEEC
PGLKPSCIAVDGTPCVPLEAALFPLAQGQRIDLLVDVPASGGAFPVLAQVEASPRRTGLV
CCCCCCEEEECCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCEEE
LATPGASVARITDTADAAQGLLSLELEGRLSAAMPLAARKPDKSFSLLLGEQPGYRWTIN
EECCCCCEEEEECCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEC
GAVYGEAPPFVVNQGERVEMTFMNPTSMNHPMHLHGHHFQVVGIGTRRFSGAMRDTVNVP
CEEECCCCCEEECCCCEEEEEEECCCCCCCCEEECCCEEEEEEECHHHHCCHHHCCCCCC
PRTPVTIAFDAGPKGDWFLHCHHLYHMATGMMGVVRVA
CCCCEEEEECCCCCCCEEEEHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]