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The map label for this gene is lysR [H]

Identifier: 158423069

GI number: 158423069

Start: 1645921

End: 1646847

Strand: Direct

Name: lysR [H]

Synonym: AZC_1445

Alternate gene names: 158423069

Gene position: 1645921-1646847 (Clockwise)

Preceding gene: 158423058

Following gene: 158423071

Centisome position: 30.65

GC content: 67.85

Gene sequence:

>927_bases
ATGATCGATCCCCGCATCAAGTTCCGCCATCTCCAGACGCTGATGGAAGTGGCGCGCCAGAAGAGCGTGGGCAAGGCCGC
GCAGGCGCTCCATGTCAGCCAGCCGGCGGTGACCAAGACAGTGCGGGAGCTGGAGGAGGTGCTTGGGGCGGCGCTGTTCG
AACGCGAGGGGCGGGGCATCCGGCTGACGCGGGCGGGGGAGGTGTTTCTCCACCACGCGGGTGCGGCCCTCGCCGCCGTA
CGGCAGGGGCTCGATTCCGTTTCCCACGAGCGGGCGGGGGCCGCCCCCTTGCTGCGGATTGGCGCGCTGCCCACCGTCTC
CACCCGCATCATGCCGCCAGCCATGGCGCTGTTTCTCAAGGCCCAGCCCTGGAGCCGTGTGAAGATCGTGACAGGCGAGA
ATTCCGTTCTCCTCGAACAGCTTCGGGTCGGCGATCTCGATCTGGTGGTGGGCCGCCTCGCCGCGCCCGAAAAAATGGCG
GGCTTTTCCTTCGAGCATCTCTATTCCGAGCCGGTGGTGTTCGCCGTGCGGCGCGGCCATCCGCTCCTGGGGGGGCAGGC
GGTGCCGTTCGATGACATCGCCCGCTATCCCGTGCTGATGCCGACCGCCGGCTCCATCATCCGCCCCATCGTGGACAGCT
ATCTGATCGGCAACGGGATTTCAGCCCTGCCCAACCAGGTTGAGACGGTGTCCGACGCCTTCGGACGGGCCTTCGTGCGG
GCGAGCGACGCGGTCTGGATCATCTCCGAGGGCGTGGTGGCGCAGGATATCGCCGAAGGCCTTCTGGGCCGTTTGCCGGT
GGATACGGGCAGCACACGGGGGCCGGTCGGCCTGACCGTGCGGGCGGGGGAAACACCCTCCTTCCCCTTGGCCCTGCTGG
TTGATTTCATCCGCGAGGCGGCGCGGGACGTGTTGGCAATGGCTTGA

Upstream 100 bases:

>100_bases
ATGAACGGCACGGGCAGCTCCTCCGTGCTCAATTTCGTCGTTTGAAGGCCCCGCGTAAAATGATATTTCCGGAACGATCT
ATAACCTGAGGGTTATGTGG

Downstream 100 bases:

>100_bases
GCCGCGCCGCGGATGATACTCCTCAATAAGGAAGGCCGACGTAGTTCTCCGCCAGAGCCGCGCGGGCAGCATGCGAGGAG
AGCGTGTAGGCGATCTCCGC

Product: transcriptional regulator

Products: NA

Alternate protein names: Pca operon transcriptional activator [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MIDPRIKFRHLQTLMEVARQKSVGKAAQALHVSQPAVTKTVRELEEVLGAALFEREGRGIRLTRAGEVFLHHAGAALAAV
RQGLDSVSHERAGAAPLLRIGALPTVSTRIMPPAMALFLKAQPWSRVKIVTGENSVLLEQLRVGDLDLVVGRLAAPEKMA
GFSFEHLYSEPVVFAVRRGHPLLGGQAVPFDDIARYPVLMPTAGSIIRPIVDSYLIGNGISALPNQVETVSDAFGRAFVR
ASDAVWIISEGVVAQDIAEGLLGRLPVDTGSTRGPVGLTVRAGETPSFPLALLVDFIREAARDVLAMA

Sequences:

>Translated_308_residues
MIDPRIKFRHLQTLMEVARQKSVGKAAQALHVSQPAVTKTVRELEEVLGAALFEREGRGIRLTRAGEVFLHHAGAALAAV
RQGLDSVSHERAGAAPLLRIGALPTVSTRIMPPAMALFLKAQPWSRVKIVTGENSVLLEQLRVGDLDLVVGRLAAPEKMA
GFSFEHLYSEPVVFAVRRGHPLLGGQAVPFDDIARYPVLMPTAGSIIRPIVDSYLIGNGISALPNQVETVSDAFGRAFVR
ASDAVWIISEGVVAQDIAEGLLGRLPVDTGSTRGPVGLTVRAGETPSFPLALLVDFIREAARDVLAMA
>Mature_308_residues
MIDPRIKFRHLQTLMEVARQKSVGKAAQALHVSQPAVTKTVRELEEVLGAALFEREGRGIRLTRAGEVFLHHAGAALAAV
RQGLDSVSHERAGAAPLLRIGALPTVSTRIMPPAMALFLKAQPWSRVKIVTGENSVLLEQLRVGDLDLVVGRLAAPEKMA
GFSFEHLYSEPVVFAVRRGHPLLGGQAVPFDDIARYPVLMPTAGSIIRPIVDSYLIGNGISALPNQVETVSDAFGRAFVR
ASDAVWIISEGVVAQDIAEGLLGRLPVDTGSTRGPVGLTVRAGETPSFPLALLVDFIREAARDVLAMA

Specific function: Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=300, Percent_Identity=33.3333333333333, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1787601, Length=198, Percent_Identity=31.8181818181818, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790399, Length=203, Percent_Identity=29.5566502463054, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI157672245, Length=215, Percent_Identity=31.6279069767442, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788887, Length=181, Percent_Identity=30.939226519337, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=199, Percent_Identity=26.1306532663317, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789506, Length=178, Percent_Identity=26.4044943820225, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790262, Length=296, Percent_Identity=27.027027027027, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790208, Length=221, Percent_Identity=28.0542986425339, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788748, Length=215, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788297, Length=210, Percent_Identity=30.4761904761905, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787879, Length=207, Percent_Identity=28.0193236714976, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786202, Length=148, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787530, Length=320, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=198, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787589, Length=252, Percent_Identity=26.5873015873016, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082024, Length=172, Percent_Identity=27.3255813953488, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR012787
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32993; Mature: 32993

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDPRIKFRHLQTLMEVARQKSVGKAAQALHVSQPAVTKTVRELEEVLGAALFEREGRGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
RLTRAGEVFLHHAGAALAAVRQGLDSVSHERAGAAPLLRIGALPTVSTRIMPPAMALFLK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHCCCHHHHHHEE
AQPWSRVKIVTGENSVLLEQLRVGDLDLVVGRLAAPEKMAGFSFEHLYSEPVVFAVRRGH
CCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHCCCHHHCCCCHHHHHCCCEEEEEECCC
PLLGGQAVPFDDIARYPVLMPTAGSIIRPIVDSYLIGNGISALPNQVETVSDAFGRAFVR
CCCCCCCCCHHHHHCCCEECCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHC
ASDAVWIISEGVVAQDIAEGLLGRLPVDTGSTRGPVGLTVRAGETPSFPLALLVDFIREA
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
ARDVLAMA
HHHHHHCC
>Mature Secondary Structure
MIDPRIKFRHLQTLMEVARQKSVGKAAQALHVSQPAVTKTVRELEEVLGAALFEREGRGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
RLTRAGEVFLHHAGAALAAVRQGLDSVSHERAGAAPLLRIGALPTVSTRIMPPAMALFLK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHCCCHHHHHHEE
AQPWSRVKIVTGENSVLLEQLRVGDLDLVVGRLAAPEKMAGFSFEHLYSEPVVFAVRRGH
CCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHCCCHHHCCCCHHHHHCCCEEEEEECCC
PLLGGQAVPFDDIARYPVLMPTAGSIIRPIVDSYLIGNGISALPNQVETVSDAFGRAFVR
CCCCCCCCCHHHHHCCCEECCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHC
ASDAVWIISEGVVAQDIAEGLLGRLPVDTGSTRGPVGLTVRAGETPSFPLALLVDFIREA
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
ARDVLAMA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]