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The map label for this gene is lysR [H]

Identifier: 158422935

GI number: 158422935

Start: 1469073

End: 1469990

Strand: Reverse

Name: lysR [H]

Synonym: AZC_1311

Alternate gene names: 158422935

Gene position: 1469990-1469073 (Counterclockwise)

Preceding gene: 158422938

Following gene: 158422932

Centisome position: 27.38

GC content: 66.67

Gene sequence:

>918_bases
ATGAGACCCCATTTCGCCGAATATCTGGCTACCTTTGTGGATGTGGTGCGCGCGGGAAGCTTCTCCGGTGCCGCGCGCCG
GCGTGCAGTGACGCCGTCGGCCATCGTCCGCCAGATCGACGCCCTGGAGCGGGATCTTGGCGTTTCCCTGTTCATCCGGT
CGACGCGCGCGCTCACGCTCACTGACGCCGGCCAGAGGCTGCACGAGCGGGCCGTGCGCCATCTCGATGACCTCGCGGAT
ACCCACGCGGAGATCGCAGCCTTCGAGGGCTCGGTCACAGGCACTCTGCGCATCGCCTGCTTCCCCACCTTCGGAAAACG
CTACGTGCTTCCCGTTGTGGTGGGCCTGCAGGCCAAACATCCCGCCCTGCTGGTCGAACTGGACCTGACGGAGCGGCTGG
CCGACCCCGTGGCGGAGCGTCTCGACGTCGTCATCCGAATGGGCGCACTGACCGACAGCACGCTGATCGCGACCAAGCTT
GCACCGCTCGCGCGCCTGCTGGTCGCCAGCCCCGCGTATCTGGCACGGGCAGGCACGCCCACAAGCGCGGCGGATCTCTC
ATCGCATCGGCTGATCGACAAGCTTCACGGCGCTGATCTCCTGGGATGGCGCGATGTACTTGGCTGCCCCGCCGGCTTTG
GCGGAAACGGCACCGTGGCGCTCCGTTCCGATGATTTCGAAGCGCAGCGCGCCGCGGCAGAGGCCGGGCTCGGGATCGCA
TTCCTGTCGAGTTGGGTCGTCGGACCGGACGTGAAGGCCGGAAAATTGATCCGCCTGCTGTCAGGCGACGAGCCCTGGAA
CCAAGGGCCGTCGGGCGTTTATGCCCTGCGGGCCCTGCCGCAGCCGAGCGCCAAGGTCAAAGCCTTCATTGAAGGGCTGC
GGAAAACAATCGGGAGCCCGCCAGTTTGGGAGCCGTGA

Upstream 100 bases:

>100_bases
TTGCGGTGGGGCGCGCGGTGTCGGCACAGCAAATATGCGGGTGTCCAGAACCTCCGATAAGTCATAGGGTTCGGCAAACG
GCTTTGCCTGGATCGCAAAG

Downstream 100 bases:

>100_bases
TCGACGCGTTCATCCCAAGCCTCGCCTTGGCGACCGCAGCCTCGCGAATGGTGCCGGCGCGGGGAATCTCTACCGTAAAC
GTGCCAAGGGCATCGGTATC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRPHFAEYLATFVDVVRAGSFSGAARRRAVTPSAIVRQIDALERDLGVSLFIRSTRALTLTDAGQRLHERAVRHLDDLAD
THAEIAAFEGSVTGTLRIACFPTFGKRYVLPVVVGLQAKHPALLVELDLTERLADPVAERLDVVIRMGALTDSTLIATKL
APLARLLVASPAYLARAGTPTSAADLSSHRLIDKLHGADLLGWRDVLGCPAGFGGNGTVALRSDDFEAQRAAAEAGLGIA
FLSSWVVGPDVKAGKLIRLLSGDEPWNQGPSGVYALRALPQPSAKVKAFIEGLRKTIGSPPVWEP

Sequences:

>Translated_305_residues
MRPHFAEYLATFVDVVRAGSFSGAARRRAVTPSAIVRQIDALERDLGVSLFIRSTRALTLTDAGQRLHERAVRHLDDLAD
THAEIAAFEGSVTGTLRIACFPTFGKRYVLPVVVGLQAKHPALLVELDLTERLADPVAERLDVVIRMGALTDSTLIATKL
APLARLLVASPAYLARAGTPTSAADLSSHRLIDKLHGADLLGWRDVLGCPAGFGGNGTVALRSDDFEAQRAAAEAGLGIA
FLSSWVVGPDVKAGKLIRLLSGDEPWNQGPSGVYALRALPQPSAKVKAFIEGLRKTIGSPPVWEP
>Mature_305_residues
MRPHFAEYLATFVDVVRAGSFSGAARRRAVTPSAIVRQIDALERDLGVSLFIRSTRALTLTDAGQRLHERAVRHLDDLAD
THAEIAAFEGSVTGTLRIACFPTFGKRYVLPVVVGLQAKHPALLVELDLTERLADPVAERLDVVIRMGALTDSTLIATKL
APLARLLVASPAYLARAGTPTSAADLSSHRLIDKLHGADLLGWRDVLGCPAGFGGNGTVALRSDDFEAQRAAAEAGLGIA
FLSSWVVGPDVKAGKLIRLLSGDEPWNQGPSGVYALRALPQPSAKVKAFIEGLRKTIGSPPVWEP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=31.8791946308725, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789639, Length=185, Percent_Identity=36.2162162162162, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789440, Length=306, Percent_Identity=29.0849673202614, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=32.3024054982818, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=33.5640138408304, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787128, Length=269, Percent_Identity=28.996282527881, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787589, Length=268, Percent_Identity=29.8507462686567, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=26.984126984127, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI157672245, Length=144, Percent_Identity=34.0277777777778, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI145693105, Length=162, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=122, Percent_Identity=36.0655737704918, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786448, Length=246, Percent_Identity=28.8617886178862, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=188, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786713, Length=245, Percent_Identity=28.1632653061224, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32548; Mature: 32548

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPHFAEYLATFVDVVRAGSFSGAARRRAVTPSAIVRQIDALERDLGVSLFIRSTRALTL
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEE
TDAGQRLHERAVRHLDDLADTHAEIAAFEGSVTGTLRIACFPTFGKRYVLPVVVGLQAKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEHHEEECCCCC
PALLVELDLTERLADPVAERLDVVIRMGALTDSTLIATKLAPLARLLVASPAYLARAGTP
CEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCC
TSAADLSSHRLIDKLHGADLLGWRDVLGCPAGFGGNGTVALRSDDFEAQRAAAEAGLGIA
CCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCHHH
FLSSWVVGPDVKAGKLIRLLSGDEPWNQGPSGVYALRALPQPSAKVKAFIEGLRKTIGSP
HHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
PVWEP
CCCCC
>Mature Secondary Structure
MRPHFAEYLATFVDVVRAGSFSGAARRRAVTPSAIVRQIDALERDLGVSLFIRSTRALTL
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEE
TDAGQRLHERAVRHLDDLADTHAEIAAFEGSVTGTLRIACFPTFGKRYVLPVVVGLQAKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEHHEEECCCCC
PALLVELDLTERLADPVAERLDVVIRMGALTDSTLIATKLAPLARLLVASPAYLARAGTP
CEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCC
TSAADLSSHRLIDKLHGADLLGWRDVLGCPAGFGGNGTVALRSDDFEAQRAAAEAGLGIA
CCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCHHH
FLSSWVVGPDVKAGKLIRLLSGDEPWNQGPSGVYALRALPQPSAKVKAFIEGLRKTIGSP
HHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
PVWEP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]