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The map label for this gene is trxB [H]

Identifier: 158422772

GI number: 158422772

Start: 1280724

End: 1281683

Strand: Direct

Name: trxB [H]

Synonym: AZC_1148

Alternate gene names: 158422772

Gene position: 1280724-1281683 (Clockwise)

Preceding gene: 158422770

Following gene: 158422773

Centisome position: 23.85

GC content: 68.02

Gene sequence:

>960_bases
ATGGCTTCCCACAGCAAGGTCATCATCATCGGGTCCGGCCCGGCCGGGTACACGGCGGCGATCTACGCCGCCCGCGCCAT
GCTGGAGCCGATCCTGTTCGAAGGCATCCAGCCCGGCGGCCAGCTGACCATCACCACCGATGTCGAGAACTACCCTGGTT
TCGCCGATGTCATTCAGGGGCCATGGCTCATGGAGCAGATGCGCGCGCAGGCCGAGCACGTCGGCACGCGCATCCTCTCC
GAGCATGTGGCGAGCCTCGACCTCTCCCGGCGTCCGTTCAAGATGGTGACGGAAGGCGGGGAGACCTATGTGGCGGACGT
CGTGATCCTCGCCACCGGCGCGCAGGCCCGCTGGCTCGGCCTCGGGTCGGAGGAAGCCTATCGCGGCTTCGGCGTTTCCG
CCTGCGCCACCTGCGACGGCTTCTTCTATCGCGGCAAGGACGTGGTGGTGGTGGGCGGCGGCAACACGGCCGTCGAGGAA
GCGCTCTTCCTCACCAATTTCGCCAGCAAGGTCACGCTGGTGCACCGCCGCGACAAGCTGAGGGCCGAGCGCATCCTCCA
GGACCGCCTGTTCGCCCACCCGAAGGTCTCGGTGGTGTGGAATGCGGCCATCGATGAAATCCTCGGCGTCAGCGAGCCCG
TATCGAAGGTGACGGGCGTGCGGCTGAAGGACGTGAACACCGGCGCCCATGCGGAGCTGGCCACCGATGGCGTGTTCATC
GCCATCGGCCATGCCCCCTCGACGGCGCTGGTGGAAGGTCAGCTTCGGATCAAGTCCGGCGGTTATGTTTGGACGGCGCC
GGATTCCACGGCCACCTCCGTGCCCGGCGTCTTCGCCGCCGGAGACGTGGCCGACGACGTGTTCCGACAGGCGGTGACGG
CCGCCGGCCGGGGCTGCATGGCGGCGCTGGAGGCGGAACGCTTCCTCGCGCAGCACGAGGTGGCGGAAGCCGCAGAGTAG

Upstream 100 bases:

>100_bases
GCATAGCTCTTTGTCAATGCGTCCGATCTCGGCTGCGCCTACGCGCCGGCGCCGGATGCGGGCGGTCCCGCATGGGCACC
GTCGAGGTTCGAGGACGGAA

Downstream 100 bases:

>100_bases
GCCGCTGGAGTACGCGGCGTTTCGCACGGGCCTCAGGCCGTCGGAGCGCGCGTCCTCTTCCAACAAGTTAGGGGGCGATC
CCTCAGGTCGTGTTGGCTCA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MASHSKVIIIGSGPAGYTAAIYAARAMLEPILFEGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMRAQAEHVGTRILS
EHVASLDLSRRPFKMVTEGGETYVADVVILATGAQARWLGLGSEEAYRGFGVSACATCDGFFYRGKDVVVVGGGNTAVEE
ALFLTNFASKVTLVHRRDKLRAERILQDRLFAHPKVSVVWNAAIDEILGVSEPVSKVTGVRLKDVNTGAHAELATDGVFI
AIGHAPSTALVEGQLRIKSGGYVWTAPDSTATSVPGVFAAGDVADDVFRQAVTAAGRGCMAALEAERFLAQHEVAEAAE

Sequences:

>Translated_319_residues
MASHSKVIIIGSGPAGYTAAIYAARAMLEPILFEGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMRAQAEHVGTRILS
EHVASLDLSRRPFKMVTEGGETYVADVVILATGAQARWLGLGSEEAYRGFGVSACATCDGFFYRGKDVVVVGGGNTAVEE
ALFLTNFASKVTLVHRRDKLRAERILQDRLFAHPKVSVVWNAAIDEILGVSEPVSKVTGVRLKDVNTGAHAELATDGVFI
AIGHAPSTALVEGQLRIKSGGYVWTAPDSTATSVPGVFAAGDVADDVFRQAVTAAGRGCMAALEAERFLAQHEVAEAAE
>Mature_318_residues
ASHSKVIIIGSGPAGYTAAIYAARAMLEPILFEGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMRAQAEHVGTRILSE
HVASLDLSRRPFKMVTEGGETYVADVVILATGAQARWLGLGSEEAYRGFGVSACATCDGFFYRGKDVVVVGGGNTAVEEA
LFLTNFASKVTLVHRRDKLRAERILQDRLFAHPKVSVVWNAAIDEILGVSEPVSKVTGVRLKDVNTGAHAELATDGVFIA
IGHAPSTALVEGQLRIKSGGYVWTAPDSTATSVPGVFAAGDVADDVFRQAVTAAGRGCMAALEAERFLAQHEVAEAAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=53.6507936507937, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=33.7579617834395, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=47.8125, Blast_Score=295, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=47.5, Blast_Score=294, Evalue=1e-80,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33816; Mature: 33685

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASHSKVIIIGSGPAGYTAAIYAARAMLEPILFEGIQPGGQLTITTDVENYPGFADVIQG
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCC
PWLMEQMRAQAEHVGTRILSEHVASLDLSRRPFKMVTEGGETYVADVVILATGAQARWLG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEEEECCCCEEEEE
LGSEEAYRGFGVSACATCDGFFYRGKDVVVVGGGNTAVEEALFLTNFASKVTLVHRRDKL
CCCHHHHCCCCCHHHHHCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEEEHHHHHH
RAERILQDRLFAHPKVSVVWNAAIDEILGVSEPVSKVTGVRLKDVNTGAHAELATDGVFI
HHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHCCCEEEECCCCCCCEEECCCEEE
AIGHAPSTALVEGQLRIKSGGYVWTAPDSTATSVPGVFAAGDVADDVFRQAVTAAGRGCM
EECCCCCCEEEEEEEEEECCCEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCHHH
AALEAERFLAQHEVAEAAE
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASHSKVIIIGSGPAGYTAAIYAARAMLEPILFEGIQPGGQLTITTDVENYPGFADVIQG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCC
PWLMEQMRAQAEHVGTRILSEHVASLDLSRRPFKMVTEGGETYVADVVILATGAQARWLG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEEEECCCCEEEEE
LGSEEAYRGFGVSACATCDGFFYRGKDVVVVGGGNTAVEEALFLTNFASKVTLVHRRDKL
CCCHHHHCCCCCHHHHHCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEEEHHHHHH
RAERILQDRLFAHPKVSVVWNAAIDEILGVSEPVSKVTGVRLKDVNTGAHAELATDGVFI
HHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHCCCEEEECCCCCCCEEECCCEEE
AIGHAPSTALVEGQLRIKSGGYVWTAPDSTATSVPGVFAAGDVADDVFRQAVTAAGRGCM
EECCCCCCEEEEEEEEEECCCEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCHHH
AALEAERFLAQHEVAEAAE
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]