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The map label for this gene is lysR [H]

Identifier: 158422773

GI number: 158422773

Start: 1281818

End: 1282708

Strand: Direct

Name: lysR [H]

Synonym: AZC_1149

Alternate gene names: 158422773

Gene position: 1281818-1282708 (Clockwise)

Preceding gene: 158422772

Following gene: 158422774

Centisome position: 23.87

GC content: 65.32

Gene sequence:

>891_bases
ATGGACTGGGACAAGCTCAAGGTTTTTCACGTGGCCGCCGAGGCCGGGTCCTTCACCCATGCGGGCGAGACACTGGGCCT
GTCCCAGTCCGCCGTCAGCCGCCAGGTTTCGGCGCTGGAGCAGGAACTGAAGGTTCCCCTGTTCCACCGCCATGCCCGCG
GCCTGATCCTGACGGAGCAGGGCGAACTGCTCTATCGCACCGCCCATGAGGTGTTCCTCAAGCTGGAATCGGCCCGCGCC
CAGCTCACCGACAGCCGCGAGAAGCCGAACGGCGAACTGCGCGTCACCACAACGGTCGGCCTCGGCACCCATTGGCTGAC
CGCCCGCGTGGGCGAGTTCGTGGAGCTTTATCCGGACATCCGCATCCAGCTCATCCTCACCGACGAGGAACTGGATCTCG
CCATGCGCGAGGCGGACGTCGCCATCCGCATGCGCCAGCCGGTGCAGCCGGATCTGGTGCAGCGCAAGCTCTTCACCGTG
CATTTCCACGCCTATGCCTCGGTGGATTATCTCAAGCGCCATGGCCAGCCGCGCACGCTGGAAGAACTGGACAAGCACCG
CATCCTCCTGCTCGGCGGGCCGATCCCGAGCTATTTCCAGGGCCTCAACTGGCTGGAGCATGCGGGCCGCGACGGTTCGA
CGCCCCGCGTGCCGGCCTTCGAGGTCAACAGCGTGCTCGGCCTGAAGCGGGCCGTGGAGCGCGGCGTCGGCATCGGCACG
CTGCCCGATTATCTCTCGGATGACTCTTCGTCGCTCGTGCAGCTCTTCACCGACCGCGAGACGCCTCAACTGGAGGCTTA
CTTCACCTATGCTCAGGAAATGCGCTCCGTGGCGCGCATCCAGGTGTTCCGGGACTTCCTGATTTCGAAGGCGCAGCGCT
GGAGCTACTGA

Upstream 100 bases:

>100_bases
AGGCCGTCGGAGCGCGCGTCCTCTTCCAACAAGTTAGGGGGCGATCCCTCAGGTCGTGTTGGCTCAACAGGACCGGATCG
CGCCCTAAGGGCAGGGTGTG

Downstream 100 bases:

>100_bases
GCGTGACAGGGGAATGACGCGGGCGTCGTTGGATCACAAATGAGCCAAGCGCCGCGCACATGCCTGACATGCGGTCATTC
CGCATTGCATTATGCCTACA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALEQELKVPLFHRHARGLILTEQGELLYRTAHEVFLKLESARA
QLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELYPDIRIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRKLFTV
HFHAYASVDYLKRHGQPRTLEELDKHRILLLGGPIPSYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
LPDYLSDDSSSLVQLFTDRETPQLEAYFTYAQEMRSVARIQVFRDFLISKAQRWSY

Sequences:

>Translated_296_residues
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALEQELKVPLFHRHARGLILTEQGELLYRTAHEVFLKLESARA
QLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELYPDIRIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRKLFTV
HFHAYASVDYLKRHGQPRTLEELDKHRILLLGGPIPSYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
LPDYLSDDSSSLVQLFTDRETPQLEAYFTYAQEMRSVARIQVFRDFLISKAQRWSY
>Mature_296_residues
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALEQELKVPLFHRHARGLILTEQGELLYRTAHEVFLKLESARA
QLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELYPDIRIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRKLFTV
HFHAYASVDYLKRHGQPRTLEELDKHRILLLGGPIPSYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
LPDYLSDDSSSLVQLFTDRETPQLEAYFTYAQEMRSVARIQVFRDFLISKAQRWSY

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=33.7931034482759, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87081978, Length=188, Percent_Identity=30.3191489361702, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787128, Length=307, Percent_Identity=28.6644951140065, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789440, Length=186, Percent_Identity=29.5698924731183, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1789173, Length=295, Percent_Identity=27.7966101694915, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789639, Length=251, Percent_Identity=27.0916334661355, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=25.5102040816327, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787589, Length=270, Percent_Identity=27.037037037037, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788706, Length=291, Percent_Identity=25.085910652921, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI157672245, Length=251, Percent_Identity=27.8884462151394, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI145693105, Length=144, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786448, Length=142, Percent_Identity=31.6901408450704, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788748, Length=139, Percent_Identity=33.8129496402878, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=208, Percent_Identity=28.8461538461538, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788481, Length=126, Percent_Identity=32.5396825396825, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790011, Length=199, Percent_Identity=24.6231155778894, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33665; Mature: 33665

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALEQELKVPLFHRHARGLILTEQ
CCCHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECC
GELLYRTAHEVFLKLESARAQLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELYPDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC
RIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRKLFTVHFHAYASVDYLKRHGQPRTL
EEEEEEECCHHHHHHHHHHHHEEECCCCCHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCH
EELDKHRILLLGGPIPSYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
HHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
LPDYLSDDSSSLVQLFTDRETPQLEAYFTYAQEMRSVARIQVFRDFLISKAQRWSY
CCHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALEQELKVPLFHRHARGLILTEQ
CCCHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECC
GELLYRTAHEVFLKLESARAQLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELYPDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC
RIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRKLFTVHFHAYASVDYLKRHGQPRTL
EEEEEEECCHHHHHHHHHHHHEEECCCCCHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCH
EELDKHRILLLGGPIPSYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
HHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
LPDYLSDDSSSLVQLFTDRETPQLEAYFTYAQEMRSVARIQVFRDFLISKAQRWSY
CCHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]