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The map label for this gene is pdxY [H]

Identifier: 158422688

GI number: 158422688

Start: 1192533

End: 1193381

Strand: Direct

Name: pdxY [H]

Synonym: AZC_1064

Alternate gene names: 158422688

Gene position: 1192533-1193381 (Clockwise)

Preceding gene: 158422687

Following gene: 158422689

Centisome position: 22.21

GC content: 67.96

Gene sequence:

>849_bases
ATGAACCTGCTCTCCATTCAGTCCCACGTGGCCTACGGGCATGTGGGAAATGCCTCCGCCGTCTTCCCCCTCCAGCGGCT
CGGCGTCGAGGTGTGGCCCATCCACACGGTGCAGTTCTCCAATCACACGGGCTATGGCGCCTGGCGCGGCCAGGTGTTCG
AGGCCAATGTCATCGGCGATCTGGTGGACGGCATCGCCGAGCGCGGCCAGCTTGGCCGCTGCGACGGCGTGCTCTCCGGC
TACATGGGCTCGGCGGACATCGGGGCGGCCATCCTCGATGCGGTGGCCAAGGTGCGGGCGGCCAATCCGCGGGCCGATTA
TTGCTGCGATCCGGTGATCGGCGACGTGGGCCGTGGCGTCTTCGTGCGGCCGGGCATTCCCGAATTCATGCGCGATCAGG
CGGTGCCCGCCGCCGAGGTGATCACGCCCAACCAGTTCGAGCTGGAGCTGCTCTCCGGCCGTGCTGCCGGCACCCGCGCG
GAGGCCGTCGCTGCCTGCGACGTGCTGCACGCAACGGGGCCCAAGGTCATCCTCGTGACCAGTCTCCAGACTGCCGAGAC
CCCGGACCATTCCATCGATCTCATGGCCTCCGGTCCCGATGGGCGCTTCCTCGTGCGTACGCCCCGGCTGGATGTGAGCC
TCAACGGCGCGGGTGATGCGATCGCTGCCCTGTTCTTCTTCCACTGGAAGCGCTCGGGCTCGACGGCACTGGCACTGGGG
GCGGCGGCGTCCTCCATCTATGGCCTGCTCTCGCGCACCCATGCGGAGGGCTCCCGCGAACTGCTGCTGGTGGCGGCGCA
GGACGAGTTCGTACGCCCAAGTCACGTCTTCACGGCCGAGGCGATTTAA

Upstream 100 bases:

>100_bases
CATCAGGAAAAGCGCTGCCCGCCATCAGCAGATTCCATTTGTGCCGGCTGCTGTGACGCGCTAACCGGCGCGGCAGAGTT
CCCCTCCGCGTGGCCGCACC

Downstream 100 bases:

>100_bases
GGTCAAGATTGCCGCGCCCACCGCCTGCAACCGACGGACACCCGCCCATGTCGCGCCGCTATCTCATCCTCGACGTCTTC
ACCGACCGCGCCCTTGGCGG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWPIHTVQFSNHTGYGAWRGQVFEANVIGDLVDGIAERGQLGRCDGVLSG
YMGSADIGAAILDAVAKVRAANPRADYCCDPVIGDVGRGVFVRPGIPEFMRDQAVPAAEVITPNQFELELLSGRAAGTRA
EAVAACDVLHATGPKVILVTSLQTAETPDHSIDLMASGPDGRFLVRTPRLDVSLNGAGDAIAALFFFHWKRSGSTALALG
AAASSIYGLLSRTHAEGSRELLLVAAQDEFVRPSHVFTAEAI

Sequences:

>Translated_282_residues
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWPIHTVQFSNHTGYGAWRGQVFEANVIGDLVDGIAERGQLGRCDGVLSG
YMGSADIGAAILDAVAKVRAANPRADYCCDPVIGDVGRGVFVRPGIPEFMRDQAVPAAEVITPNQFELELLSGRAAGTRA
EAVAACDVLHATGPKVILVTSLQTAETPDHSIDLMASGPDGRFLVRTPRLDVSLNGAGDAIAALFFFHWKRSGSTALALG
AAASSIYGLLSRTHAEGSRELLLVAAQDEFVRPSHVFTAEAI
>Mature_282_residues
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWPIHTVQFSNHTGYGAWRGQVFEANVIGDLVDGIAERGQLGRCDGVLSG
YMGSADIGAAILDAVAKVRAANPRADYCCDPVIGDVGRGVFVRPGIPEFMRDQAVPAAEVITPNQFELELLSGRAAGTRA
EAVAACDVLHATGPKVILVTSLQTAETPDHSIDLMASGPDGRFLVRTPRLDVSLNGAGDAIAALFFFHWKRSGSTALALG
AAASSIYGLLSRTHAEGSRELLLVAAQDEFVRPSHVFTAEAI

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=266, Percent_Identity=36.8421052631579, Blast_Score=175, Evalue=5e-44,
Organism=Escherichia coli, GI1787924, Length=284, Percent_Identity=40.8450704225352, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1788758, Length=262, Percent_Identity=29.0076335877863, Blast_Score=118, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17507759, Length=284, Percent_Identity=33.8028169014084, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17507757, Length=294, Percent_Identity=32.6530612244898, Blast_Score=134, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320806, Length=273, Percent_Identity=31.8681318681319, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324354, Length=234, Percent_Identity=35.042735042735, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45553007, Length=294, Percent_Identity=32.6530612244898, Blast_Score=160, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 29742; Mature: 29742

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWPIHTVQFSNHTGYGAWRGQVFEANVIGD
CCEEECCHHEEECCCCCCCCCCCHHHCCEEEEEEEEEEECCCCCCCEECCEEEEHHHHHH
LVDGIAERGQLGRCDGVLSGYMGSADIGAAILDAVAKVRAANPRADYCCDPVIGDVGRGV
HHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCE
FVRPGIPEFMRDQAVPAAEVITPNQFELELLSGRAAGTRAEAVAACDVLHATGPKVILVT
EECCCCHHHHHHCCCCHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEE
SLQTAETPDHSIDLMASGPDGRFLVRTPRLDVSLNGAGDAIAALFFFHWKRSGSTALALG
ECCCCCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEH
AAASSIYGLLSRTHAEGSRELLLVAAQDEFVRPSHVFTAEAI
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCC
>Mature Secondary Structure
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWPIHTVQFSNHTGYGAWRGQVFEANVIGD
CCEEECCHHEEECCCCCCCCCCCHHHCCEEEEEEEEEEECCCCCCCEECCEEEEHHHHHH
LVDGIAERGQLGRCDGVLSGYMGSADIGAAILDAVAKVRAANPRADYCCDPVIGDVGRGV
HHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCE
FVRPGIPEFMRDQAVPAAEVITPNQFELELLSGRAAGTRAEAVAACDVLHATGPKVILVT
EECCCCHHHHHHCCCCHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEE
SLQTAETPDHSIDLMASGPDGRFLVRTPRLDVSLNGAGDAIAALFFFHWKRSGSTALALG
ECCCCCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEH
AAASSIYGLLSRTHAEGSRELLLVAAQDEFVRPSHVFTAEAI
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA