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The map label for this gene is yqjQ [H]

Identifier: 158422687

GI number: 158422687

Start: 1191812

End: 1192426

Strand: Direct

Name: yqjQ [H]

Synonym: AZC_1063

Alternate gene names: 158422687

Gene position: 1191812-1192426 (Clockwise)

Preceding gene: 158422686

Following gene: 158422688

Centisome position: 22.19

GC content: 68.46

Gene sequence:

>615_bases
TTGCGCGCGGTGGATCTCGCCGATGCCGATGGCATGGACGAGTTGTGCGAATACGCCGCGCATGTTGCGCCCGACATTCT
CGTCAACAATGCGGGCTTCGGCGGTTATGGCCCCTTCGTCGAGAGCCGCCCCTCCGACGAGGTGGCGATGATCGCCACCA
ATGTGACCGCGCTCACCATGCTCGCCAAGGCGGTGCTGCCCGGCATGCTGAAACGCAAGGCGGGCCGCATCCTCAATGTG
GGGTCAACGGCGAGCTTTGCGCCGGGACCGTTCGCGGCGGTCTATGCCGCCACGAAGGCCTATGTGCTGAGCCTGTCCGA
GGCGCTGGCCGAAGAGGTCAGCGGCAGCGGCGTCACCGTCACCTGCCTGTGTCCCGGCCCCACGGAGACCGGCTTTGCCC
GCCGCGCCAGCATGAGCAGCACCCGCGTCTTCAAGGGGCCGGTGGCCGATGCCGCAGGCGTCGCCCGCACTGGCTATGAG
GCGATGATGGCCGGGCGCCGCCTTGCGGTGCCGGGGCCGGTGAACAAGCTGCTCGTCTTCGCCATCCGTTTGGTCCCGCG
CCGCGTCGTCGCCTTCATTTCCCGACGGGAACTCTCTCCCGTGCCGCCCGCCTGA

Upstream 100 bases:

>100_bases
GCGGGACGGCTACCGGCTGCTGCTCGTCTCGCGCGATCCCTCGCGGCTGGAGGATGCCGCCGCCAAGCTCCGCGCGGAGT
GGCCGGATGTCGCGCTGGAA

Downstream 100 bases:

>100_bases
CCGGTCCATCAGGAAAAGCGCTGCCCGCCATCAGCAGATTCCATTTGTGCCGGCTGCTGTGACGCGCTAACCGGCGCGGC
AGAGTTCCCCTCCGCGTGGC

Product: short-chain dehydrogenase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MRAVDLADADGMDELCEYAAHVAPDILVNNAGFGGYGPFVESRPSDEVAMIATNVTALTMLAKAVLPGMLKRKAGRILNV
GSTASFAPGPFAAVYAATKAYVLSLSEALAEEVSGSGVTVTCLCPGPTETGFARRASMSSTRVFKGPVADAAGVARTGYE
AMMAGRRLAVPGPVNKLLVFAIRLVPRRVVAFISRRELSPVPPA

Sequences:

>Translated_204_residues
MRAVDLADADGMDELCEYAAHVAPDILVNNAGFGGYGPFVESRPSDEVAMIATNVTALTMLAKAVLPGMLKRKAGRILNV
GSTASFAPGPFAAVYAATKAYVLSLSEALAEEVSGSGVTVTCLCPGPTETGFARRASMSSTRVFKGPVADAAGVARTGYE
AMMAGRRLAVPGPVNKLLVFAIRLVPRRVVAFISRRELSPVPPA
>Mature_204_residues
MRAVDLADADGMDELCEYAAHVAPDILVNNAGFGGYGPFVESRPSDEVAMIATNVTALTMLAKAVLPGMLKRKAGRILNV
GSTASFAPGPFAAVYAATKAYVLSLSEALAEEVSGSGVTVTCLCPGPTETGFARRASMSSTRVFKGPVADAAGVARTGYE
AMMAGRRLAVPGPVNKLLVFAIRLVPRRVVAFISRRELSPVPPA

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=130, Percent_Identity=31.5384615384615, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705855, Length=136, Percent_Identity=35.2941176470588, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI210032112, Length=176, Percent_Identity=25.5681818181818, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI210032110, Length=176, Percent_Identity=25.5681818181818, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI226371731, Length=148, Percent_Identity=31.7567567567568, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI142976729, Length=175, Percent_Identity=28, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32483357, Length=123, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=103, Percent_Identity=44.6601941747573, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI87082100, Length=118, Percent_Identity=38.135593220339, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787335, Length=110, Percent_Identity=37.2727272727273, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786701, Length=141, Percent_Identity=28.3687943262411, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790717, Length=110, Percent_Identity=32.7272727272727, Blast_Score=61, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=118, Percent_Identity=35.5932203389831, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640442, Length=144, Percent_Identity=31.9444444444444, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 21201; Mature: 21201

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVDLADADGMDELCEYAAHVAPDILVNNAGFGGYGPFVESRPSDEVAMIATNVTALTM
CCCCCCCCCCCHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
LAKAVLPGMLKRKAGRILNVGSTASFAPGPFAAVYAATKAYVLSLSEALAEEVSGSGVTV
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TCLCPGPTETGFARRASMSSTRVFKGPVADAAGVARTGYEAMMAGRRLAVPGPVNKLLVF
EEEECCCCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHH
AIRLVPRRVVAFISRRELSPVPPA
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRAVDLADADGMDELCEYAAHVAPDILVNNAGFGGYGPFVESRPSDEVAMIATNVTALTM
CCCCCCCCCCCHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
LAKAVLPGMLKRKAGRILNVGSTASFAPGPFAAVYAATKAYVLSLSEALAEEVSGSGVTV
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TCLCPGPTETGFARRASMSSTRVFKGPVADAAGVARTGYEAMMAGRRLAVPGPVNKLLVF
EEEECCCCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHH
AIRLVPRRVVAFISRRELSPVPPA
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]