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The map label for this gene is lldR [H]

Identifier: 158422447

GI number: 158422447

Start: 929358

End: 930164

Strand: Reverse

Name: lldR [H]

Synonym: AZC_0823

Alternate gene names: 158422447

Gene position: 930164-929358 (Counterclockwise)

Preceding gene: 158422448

Following gene: 158422446

Centisome position: 17.32

GC content: 70.14

Gene sequence:

>807_bases
TTGGTCCGACCACTCATGCGCACGCAGCACCTCTCTTCCGGCTCCCATGACGGGCGGGCATTGGCGGTGCGGCTGGTGGA
GGCGCTGGAGGCGCGGATCGCGGCCCTCGGCGCGGGCGACCGGCTGCCGGCGGAACGGGTGCTGGCGCAGGAGCTCGGCG
TTTCGCGATCGAGCATCCGCGAGGCCATCCAGCAACTCGTGAGCCGCGGGCGCCTTGTGGCGCGGCAGGGCGGCGGCACC
TTCGTGCAGGAGCCGGATCACGCCTGGACCGGCGGCGGGCTCATCGCGCCGCTCGCCCCGCTGGTGCGGGACGATCCCGC
CTACTGGCGCGATGTGATCGAGATCCGCCGCTCTCTGGATGCCAGCGCCGCCTTCTTCGCCGCCACCCGTGCCACGGCGG
AAGACAAGGCGCGGCTGGAAGCCTGCCTCGCCCAGATGAGTGCGCGCCACAGCCCCGGCGATCCGGAAGAGGATGCGCGG
GCGGATGTGGCATTCCACATGGCCGTGGCGGATGCCTCGCACAATCTTGTGCTGCGCCATGTGATGGCCGGGCTGCTGGA
TCTGCTTCAGGCCAGCATTTCCCAGAGCCTCGTCAAGCTCTATTCCGTGCCGCGCACCTTCGAGACCCTGGAGCGCCAGC
ATCGCGTGCTGGCGGAGGCCATCCTCGCCGGCACGCCAGAGACGGCGCGGGACGCCGCGCTTCAGCATCTCGACTTCGTC
GAACAGACGCTCCGCCAGATCGAAGAGGACGCCGCGCGCCTGCGGCGGGCCTCCATGCCCTTACGCCAAAAAGGAAACGC
CCGATGA

Upstream 100 bases:

>100_bases
ATCGCATGCGCGCATTTGGTCATACCAATTACGAACATACATCCTTTACACCGCATCCCCTCTGCTCCTATAGAAGAGAA
ATCGTTCCGCCAGATACCAT

Downstream 100 bases:

>100_bases
TCATCTCGTCACCGAACGACTATCGCGCCGCCGCCAAGAGCCGGCTGCCGCCCTTCCTCTTCCATTATGTGGATGGCGGT
GCCTATGCCGAATACACGCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MVRPLMRTQHLSSGSHDGRALAVRLVEALEARIAALGAGDRLPAERVLAQELGVSRSSIREAIQQLVSRGRLVARQGGGT
FVQEPDHAWTGGGLIAPLAPLVRDDPAYWRDVIEIRRSLDASAAFFAATRATAEDKARLEACLAQMSARHSPGDPEEDAR
ADVAFHMAVADASHNLVLRHVMAGLLDLLQASISQSLVKLYSVPRTFETLERQHRVLAEAILAGTPETARDAALQHLDFV
EQTLRQIEEDAARLRRASMPLRQKGNAR

Sequences:

>Translated_268_residues
MVRPLMRTQHLSSGSHDGRALAVRLVEALEARIAALGAGDRLPAERVLAQELGVSRSSIREAIQQLVSRGRLVARQGGGT
FVQEPDHAWTGGGLIAPLAPLVRDDPAYWRDVIEIRRSLDASAAFFAATRATAEDKARLEACLAQMSARHSPGDPEEDAR
ADVAFHMAVADASHNLVLRHVMAGLLDLLQASISQSLVKLYSVPRTFETLERQHRVLAEAILAGTPETARDAALQHLDFV
EQTLRQIEEDAARLRRASMPLRQKGNAR
>Mature_268_residues
MVRPLMRTQHLSSGSHDGRALAVRLVEALEARIAALGAGDRLPAERVLAQELGVSRSSIREAIQQLVSRGRLVARQGGGT
FVQEPDHAWTGGGLIAPLAPLVRDDPAYWRDVIEIRRSLDASAAFFAATRATAEDKARLEACLAQMSARHSPGDPEEDAR
ADVAFHMAVADASHNLVLRHVMAGLLDLLQASISQSLVKLYSVPRTFETLERQHRVLAEAILAGTPETARDAALQHLDFV
EQTLRQIEEDAARLRRASMPLRQKGNAR

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=219, Percent_Identity=45.2054794520548, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1786303, Length=211, Percent_Identity=39.8104265402844, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789353, Length=231, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082208, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790780, Length=220, Percent_Identity=28.6363636363636, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994955, Length=211, Percent_Identity=28.9099526066351, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29276; Mature: 29276

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRPLMRTQHLSSGSHDGRALAVRLVEALEARIAALGAGDRLPAERVLAQELGVSRSSIR
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHH
EAIQQLVSRGRLVARQGGGTFVQEPDHAWTGGGLIAPLAPLVRDDPAYWRDVIEIRRSLD
HHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
ASAAFFAATRATAEDKARLEACLAQMSARHSPGDPEEDARADVAFHMAVADASHNLVLRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
VMAGLLDLLQASISQSLVKLYSVPRTFETLERQHRVLAEAILAGTPETARDAALQHLDFV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EQTLRQIEEDAARLRRASMPLRQKGNAR
HHHHHHHHHHHHHHHHHCCCHHCCCCCC
>Mature Secondary Structure
MVRPLMRTQHLSSGSHDGRALAVRLVEALEARIAALGAGDRLPAERVLAQELGVSRSSIR
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHH
EAIQQLVSRGRLVARQGGGTFVQEPDHAWTGGGLIAPLAPLVRDDPAYWRDVIEIRRSLD
HHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
ASAAFFAATRATAEDKARLEACLAQMSARHSPGDPEEDARADVAFHMAVADASHNLVLRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
VMAGLLDLLQASISQSLVKLYSVPRTFETLERQHRVLAEAILAGTPETARDAALQHLDFV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EQTLRQIEEDAARLRRASMPLRQKGNAR
HHHHHHHHHHHHHHHHHCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]