Click here to switch to the map view.

The map label for this gene is cpg2 [H]

Identifier: 158422430

GI number: 158422430

Start: 909379

End: 910476

Strand: Reverse

Name: cpg2 [H]

Synonym: AZC_0806

Alternate gene names: 158422430

Gene position: 910476-909379 (Counterclockwise)

Preceding gene: 158422431

Following gene: 158422429

Centisome position: 16.96

GC content: 69.03

Gene sequence:

>1098_bases
ATGGAGGCGCTGCTGAAGCGCCTCGTCAACATGGAGTCGAGCAGCTTCGACAAGGAGGGCACCGACAAGGTGGGCGAGGT
GATCGCCGAGATCCTCACCGCCGAGGGCATCCTCGTCACCCGCCTGCCACAGCAAGGCTATGGCGACGTGTTCCGGGCCG
AGGTGCATGGCCGCGCCGGCGGCGCCCACGCGCTGCTGCTGGGCCACCGCGACACGGTGTTCGCCAAGGGCACGGTGGCG
AACCGGCCCTATTCCCGGAAGGACAAGCTCGCCTTCGGCCCCGGCGTCTGCGACATGAAGGCCGGGCTCGTCACCAACAT
CTTCACCCTGCGCGCCATCAAGGCGGTGGGCGGCCTCTCCTTTCCCGTGGTGGCGCTCTTCACGGGCGATGAGGAGATCG
GCTCCGGCACCGGCCGCCCGGAGATCGAGCGGGCGGCGTACGGCGCGCGGGCGGTCTTCAACACCGAGCCCGGTCGAGTC
TCCGGCAATGTGGTGACCGGCCGCAAGGGCGGCGGCTCATTCCTGATCAAGGTCACCGGCAAGGCGGCCCATTCCGGCGT
CAACCACAAGGACGGCGCGAGCGCCATCGAGACGCTCGCCCGCAAGATCGTGAAGCTGCACGCCCTCACGGATTATGAGG
CCGGCATCACCACCAATGTGGGCGTCATCAAGGGCGGCAACACCCACAATACGGTCGCCCCGTGGGCGGAGGCCGAACTG
GACCTGCGCTTCGTGACGCTGGACCAGCACAAGGCGATGACGGCGGAGATCGAACGCATCGTCGCCGAGCCGGAAGTGCC
GGGCACCACCGCCACCGTCACTCCCAAGTCCATGTTCCTGCCGCTGGAGGAGAAGCACGCCGCCGGTCTGTTCGCCCTCT
ATCGGGAAGCGGCGACCAAGGACGTGGGCTTCGACGTGGGCGGGGAGTTCACCGGCGGCTGCGCCGATTCCGGCTTCACC
GCCTCGCTCGGCGTGTCCACCCTGTGCGGCCTCGGCCCCATCGGCGGCAAGGCCCACACCGATGACGAGTTCTGCGAGCT
GGACAGCCTCGTGCCGCGCACGCAGGCGCTGGCCGCGACGCTCTGCCGCCTCGCCTGA

Upstream 100 bases:

>100_bases
TGAAGGCGCGCGCCGCATGAGCACCCTGCCCACCCCCACCGGCCTTGATGCCGCGCTGGCCGAAAAGGTCGTCGCCTGGC
TCGCACCCCGGTTCGACGAG

Downstream 100 bases:

>100_bases
GACGACGCTTCGCCTCTGTGCCCGGCCGGTGGTAAGGAGGGTCCCTCCTCCACCGGCCGGCGGTTCGACGCATGGAAAAG
AACACCCAGGAACGCCACCG

Product: peptidase

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEALLKRLVNMESSSFDKEGTDKVGEVIAEILTAEGILVTRLPQQGYGDVFRAEVHGRAGGAHALLLGHRDTVFAKGTVA
NRPYSRKDKLAFGPGVCDMKAGLVTNIFTLRAIKAVGGLSFPVVALFTGDEEIGSGTGRPEIERAAYGARAVFNTEPGRV
SGNVVTGRKGGGSFLIKVTGKAAHSGVNHKDGASAIETLARKIVKLHALTDYEAGITTNVGVIKGGNTHNTVAPWAEAEL
DLRFVTLDQHKAMTAEIERIVAEPEVPGTTATVTPKSMFLPLEEKHAAGLFALYREAATKDVGFDVGGEFTGGCADSGFT
ASLGVSTLCGLGPIGGKAHTDDEFCELDSLVPRTQALAATLCRLA

Sequences:

>Translated_365_residues
MEALLKRLVNMESSSFDKEGTDKVGEVIAEILTAEGILVTRLPQQGYGDVFRAEVHGRAGGAHALLLGHRDTVFAKGTVA
NRPYSRKDKLAFGPGVCDMKAGLVTNIFTLRAIKAVGGLSFPVVALFTGDEEIGSGTGRPEIERAAYGARAVFNTEPGRV
SGNVVTGRKGGGSFLIKVTGKAAHSGVNHKDGASAIETLARKIVKLHALTDYEAGITTNVGVIKGGNTHNTVAPWAEAEL
DLRFVTLDQHKAMTAEIERIVAEPEVPGTTATVTPKSMFLPLEEKHAAGLFALYREAATKDVGFDVGGEFTGGCADSGFT
ASLGVSTLCGLGPIGGKAHTDDEFCELDSLVPRTQALAATLCRLA
>Mature_365_residues
MEALLKRLVNMESSSFDKEGTDKVGEVIAEILTAEGILVTRLPQQGYGDVFRAEVHGRAGGAHALLLGHRDTVFAKGTVA
NRPYSRKDKLAFGPGVCDMKAGLVTNIFTLRAIKAVGGLSFPVVALFTGDEEIGSGTGRPEIERAAYGARAVFNTEPGRV
SGNVVTGRKGGGSFLIKVTGKAAHSGVNHKDGASAIETLARKIVKLHALTDYEAGITTNVGVIKGGNTHNTVAPWAEAEL
DLRFVTLDQHKAMTAEIERIVAEPEVPGTTATVTPKSMFLPLEEKHAAGLFALYREAATKDVGFDVGGEFTGGCADSGFT
ASLGVSTLCGLGPIGGKAHTDDEFCELDSLVPRTQALAATLCRLA

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 38262; Mature: 38262

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALLKRLVNMESSSFDKEGTDKVGEVIAEILTAEGILVTRLPQQGYGDVFRAEVHGRAG
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCC
GAHALLLGHRDTVFAKGTVANRPYSRKDKLAFGPGVCDMKAGLVTNIFTLRAIKAVGGLS
CCEEEEEECCCCEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
FPVVALFTGDEEIGSGTGRPEIERAAYGARAVFNTEPGRVSGNVVTGRKGGGSFLIKVTG
CCEEEEEECCHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCCEEECCCCCCEEEEEEEC
KAAHSGVNHKDGASAIETLARKIVKLHALTDYEAGITTNVGVIKGGNTHNTVAPWAEAEL
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCE
DLRFVTLDQHKAMTAEIERIVAEPEVPGTTATVTPKSMFLPLEEKHAAGLFALYREAATK
EEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHC
DVGFDVGGEFTGGCADSGFTASLGVSTLCGLGPIGGKAHTDDEFCELDSLVPRTQALAAT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
LCRLA
HHHCC
>Mature Secondary Structure
MEALLKRLVNMESSSFDKEGTDKVGEVIAEILTAEGILVTRLPQQGYGDVFRAEVHGRAG
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCC
GAHALLLGHRDTVFAKGTVANRPYSRKDKLAFGPGVCDMKAGLVTNIFTLRAIKAVGGLS
CCEEEEEECCCCEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
FPVVALFTGDEEIGSGTGRPEIERAAYGARAVFNTEPGRVSGNVVTGRKGGGSFLIKVTG
CCEEEEEECCHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCCEEECCCCCCEEEEEEEC
KAAHSGVNHKDGASAIETLARKIVKLHALTDYEAGITTNVGVIKGGNTHNTVAPWAEAEL
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCE
DLRFVTLDQHKAMTAEIERIVAEPEVPGTTATVTPKSMFLPLEEKHAAGLFALYREAATK
EEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHC
DVGFDVGGEFTGGCADSGFTASLGVSTLCGLGPIGGKAHTDDEFCELDSLVPRTQALAAT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
LCRLA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]