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The map label for this gene is yyaJ [H]

Identifier: 158422392

GI number: 158422392

Start: 868265

End: 869671

Strand: Reverse

Name: yyaJ [H]

Synonym: AZC_0768

Alternate gene names: 158422392

Gene position: 869671-868265 (Counterclockwise)

Preceding gene: 158422393

Following gene: 158422388

Centisome position: 16.2

GC content: 65.67

Gene sequence:

>1407_bases
ATGTCGACGCCAGCCTCTGCCGCGCCCCACGCGGCCACCCCCCTAGATCCAGCCTTCGACGGTCAGGCGGATATCAGCGC
CCGTATCGAACGCCTGCCGATGACCCGCAAGGTCTTCTGGACGCGCAACATCATCGGCGCGGCCACCTTCTTCGATGGCT
ACACCGTCATTGCCATCGCCTATGCCATGCCTGTTCTGGTGAAGGAGTGGGGGCTCTCGCCGCAGGAAATCGGCATGATC
CTCTCTCTCGGCTACATCGGCCAGTTGGTGGGGGCGATCTTCTTCGGCTGGCTCGCGGAGCGGATTGGCCGGCTTCATGT
GCTTCTGCTCACCATCCTGCTGTTCGTCAGCATGGACATCGCCTGCCTCACCGCATGGAGCGCCACCTCCATGATCGTGT
TCCGCTTCCTGCAGGGCATCGGAACCGGCGGCGAGGTGCCGGTGGCATCGGCTTACATCAACGAATATGTCGGAGCGCGG
ACGCGCGGGCGGTTCTTCCTGCTCTATGAGGTCATGTTCCTGCTCGGCCTCGTGGGCGCGGGAGTCATCGGCTATTTCCT
TGTGCCGGTTTACGGTTGGCGGGCTATGTTCATCGTCGGGCTCGTGCCATCGGTGCTCATGATCCCGCTGCGCTGGTTCC
TGTCCGAATCCCCGCGCTGGCTGGCCTCCCGTGGCCGCTATGCGGAGGCGGACCGCATCGTGTCCGATCTGGAGCGCAGC
GCCACCGCTGCCGGCCATGTGCTGGAAGAGCCCCGCCCCCTCGCGCTGCGCCCCGCGCAGGTCGGAAAGGGCGACTGGCG
GGAGCTGTTCCGAGGCATCTACCTGAAGCGCACGCTCATGATCTGGCCCCTGTGGTTCGCCACCCATGTGGTCAACAACG
GCATGGCCACGTGGCTGCCGACACTCTACCGGCAGGTGTTCAACCTGCCCCTCTCCACCAGCCTCGCCTACGGCTTCACC
ACATCGGGAGCCGGCGTCGTGGGCGCGCTCACCTGCGCCATGTTCATCGACAGGGTGGGCCGCAAGCGCTGGTACACATA
CGCCCTGCTTCTTGCCGCCGTGCCGTTGGGCCTGCTCGGCTGGCTGGGCGCCACATCGGCCACGCAGGTGCTGTTCTTCG
CCGCCATCACCTACGCCATCACCCAGAGCGTCACCTTCTCGCTCTATCTCTATTCGGCGGAGCTGTATCCGACCCGCATC
CGCGCCATCGCCACCGGCTTCGGCAGCGCATGGCTGCGGCTTGGGTCATCGGCGGGTCCGCTGGTGGTGGGCGCGGTGCT
CTCGGGCCTCGGCGGCATCCAGTGGGTGTTCGTCATCTTCTCGGCGCTGATCCTGGTGACCGGCGCATTCGTCGGCGCCT
TCGCCGTGGAGACCAAGGGGCGCGTTCTCGAGGAGCTTTCTCCTTAA

Upstream 100 bases:

>100_bases
GCCGGACGTGAAGGCCGGCGCGCGCCCGCTTCTCCCCATTCCGTCCGCCGGGGCCCTTCAAGGCAGCGCCGGCCAATAAA
CAACTCTGCAGGAGCGAGGA

Downstream 100 bases:

>100_bases
ACCGCACGGGGTGAACGAGGCTCCCACGTAAAAGGAAAGCCGGGACGGCGCTGACCGTCCCGGCTTTTTATGTCTTGCGG
TCGAATTGGTAGCCGCGATG

Product: MFS transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSTPASAAPHAATPLDPAFDGQADISARIERLPMTRKVFWTRNIIGAATFFDGYTVIAIAYAMPVLVKEWGLSPQEIGMI
LSLGYIGQLVGAIFFGWLAERIGRLHVLLLTILLFVSMDIACLTAWSATSMIVFRFLQGIGTGGEVPVASAYINEYVGAR
TRGRFFLLYEVMFLLGLVGAGVIGYFLVPVYGWRAMFIVGLVPSVLMIPLRWFLSESPRWLASRGRYAEADRIVSDLERS
ATAAGHVLEEPRPLALRPAQVGKGDWRELFRGIYLKRTLMIWPLWFATHVVNNGMATWLPTLYRQVFNLPLSTSLAYGFT
TSGAGVVGALTCAMFIDRVGRKRWYTYALLLAAVPLGLLGWLGATSATQVLFFAAITYAITQSVTFSLYLYSAELYPTRI
RAIATGFGSAWLRLGSSAGPLVVGAVLSGLGGIQWVFVIFSALILVTGAFVGAFAVETKGRVLEELSP

Sequences:

>Translated_468_residues
MSTPASAAPHAATPLDPAFDGQADISARIERLPMTRKVFWTRNIIGAATFFDGYTVIAIAYAMPVLVKEWGLSPQEIGMI
LSLGYIGQLVGAIFFGWLAERIGRLHVLLLTILLFVSMDIACLTAWSATSMIVFRFLQGIGTGGEVPVASAYINEYVGAR
TRGRFFLLYEVMFLLGLVGAGVIGYFLVPVYGWRAMFIVGLVPSVLMIPLRWFLSESPRWLASRGRYAEADRIVSDLERS
ATAAGHVLEEPRPLALRPAQVGKGDWRELFRGIYLKRTLMIWPLWFATHVVNNGMATWLPTLYRQVFNLPLSTSLAYGFT
TSGAGVVGALTCAMFIDRVGRKRWYTYALLLAAVPLGLLGWLGATSATQVLFFAAITYAITQSVTFSLYLYSAELYPTRI
RAIATGFGSAWLRLGSSAGPLVVGAVLSGLGGIQWVFVIFSALILVTGAFVGAFAVETKGRVLEELSP
>Mature_467_residues
STPASAAPHAATPLDPAFDGQADISARIERLPMTRKVFWTRNIIGAATFFDGYTVIAIAYAMPVLVKEWGLSPQEIGMIL
SLGYIGQLVGAIFFGWLAERIGRLHVLLLTILLFVSMDIACLTAWSATSMIVFRFLQGIGTGGEVPVASAYINEYVGART
RGRFFLLYEVMFLLGLVGAGVIGYFLVPVYGWRAMFIVGLVPSVLMIPLRWFLSESPRWLASRGRYAEADRIVSDLERSA
TAAGHVLEEPRPLALRPAQVGKGDWRELFRGIYLKRTLMIWPLWFATHVVNNGMATWLPTLYRQVFNLPLSTSLAYGFTT
SGAGVVGALTCAMFIDRVGRKRWYTYALLLAAVPLGLLGWLGATSATQVLFFAAITYAITQSVTFSLYLYSAELYPTRIR
AIATGFGSAWLRLGSSAGPLVVGAVLSGLGGIQWVFVIFSALILVTGAFVGAFAVETKGRVLEELSP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=450, Percent_Identity=24.4444444444444, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI24308167, Length=456, Percent_Identity=26.3157894736842, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI31542327, Length=383, Percent_Identity=27.4151436031332, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI11415038, Length=412, Percent_Identity=26.4563106796117, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI7662270, Length=343, Percent_Identity=24.7813411078717, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4506999, Length=409, Percent_Identity=26.8948655256724, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI166064021, Length=382, Percent_Identity=27.7486910994764, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI24497490, Length=400, Percent_Identity=26.75, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI4507005, Length=393, Percent_Identity=25.4452926208651, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI166197673, Length=384, Percent_Identity=28.6458333333333, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI302148518, Length=348, Percent_Identity=25.8620689655172, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI23510410, Length=334, Percent_Identity=26.9461077844311, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI216548223, Length=305, Percent_Identity=23.6065573770492, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI20070188, Length=374, Percent_Identity=28.8770053475936, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI24497476, Length=374, Percent_Identity=28.8770053475936, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI33457322, Length=338, Percent_Identity=23.9644970414201, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI262399383, Length=265, Percent_Identity=25.6603773584906, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI24497478, Length=355, Percent_Identity=28.169014084507, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI24497480, Length=354, Percent_Identity=27.9661016949153, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI24497497, Length=376, Percent_Identity=23.936170212766, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI90669191, Length=371, Percent_Identity=23.1805929919137, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI73695465, Length=202, Percent_Identity=28.2178217821782, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI296080721, Length=376, Percent_Identity=26.3297872340426, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI296080719, Length=376, Percent_Identity=26.3297872340426, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI24497499, Length=376, Percent_Identity=26.3297872340426, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI21553331, Length=340, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1788068, Length=465, Percent_Identity=25.8064516129032, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87082159, Length=400, Percent_Identity=27.25, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786229, Length=420, Percent_Identity=24.7619047619048, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789207, Length=307, Percent_Identity=27.6872964169381, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788074, Length=398, Percent_Identity=26.8844221105528, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789312, Length=312, Percent_Identity=25.9615384615385, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081723, Length=364, Percent_Identity=28.2967032967033, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082231, Length=188, Percent_Identity=27.1276595744681, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790463, Length=442, Percent_Identity=22.8506787330317, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082404, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32564663, Length=425, Percent_Identity=22.5882352941176, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71996338, Length=430, Percent_Identity=26.046511627907, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565978, Length=336, Percent_Identity=23.5119047619048, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71986689, Length=344, Percent_Identity=22.9651162790698, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193202825, Length=344, Percent_Identity=22.9651162790698, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI133900837, Length=378, Percent_Identity=26.7195767195767, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72003720, Length=389, Percent_Identity=26.7352185089974, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988651, Length=202, Percent_Identity=27.7227722772277, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565976, Length=227, Percent_Identity=27.3127753303965, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193209133, Length=416, Percent_Identity=22.5961538461538, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560496, Length=433, Percent_Identity=23.7875288683603, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323653, Length=440, Percent_Identity=23.8636363636364, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922616, Length=447, Percent_Identity=28.1879194630872, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI62484254, Length=388, Percent_Identity=25.2577319587629, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24640198, Length=451, Percent_Identity=21.9512195121951, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24640196, Length=451, Percent_Identity=21.9512195121951, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24640200, Length=451, Percent_Identity=21.9512195121951, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24649622, Length=415, Percent_Identity=26.0240963855422, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221330907, Length=392, Percent_Identity=25.5102040816327, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668456, Length=404, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355657, Length=352, Percent_Identity=27.8409090909091, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922874, Length=380, Percent_Identity=22.1052631578947, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24649618, Length=356, Percent_Identity=25.8426966292135, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45549297, Length=498, Percent_Identity=23.2931726907631, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24649616, Length=368, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648211, Length=346, Percent_Identity=25.7225433526012, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922134, Length=430, Percent_Identity=25.8139534883721, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51070; Mature: 50939

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPASAAPHAATPLDPAFDGQADISARIERLPMTRKVFWTRNIIGAATFFDGYTVIAIA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHH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HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]