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The map label for this gene is iclR [H]

Identifier: 158422388

GI number: 158422388

Start: 863576

End: 864370

Strand: Reverse

Name: iclR [H]

Synonym: AZC_0764

Alternate gene names: 158422388

Gene position: 864370-863576 (Counterclockwise)

Preceding gene: 158422392

Following gene: 158422383

Centisome position: 16.1

GC content: 68.18

Gene sequence:

>795_bases
GTGATCATGGCAACTGACGGTTTGACTTCTCCCACGGACAGCGTGCCGGCGCTGCGGCGGGCCGTGCGCATCCTCGACCA
TGTGGGCAGCGCGAATGCGCCCCTGACGGCAGCGGAAATCACCCGCGCGCTTGCACTGCCCAAAAGCAGTGCGCACGGGC
TCATTTCGGCACTGCTGGACCTCGGGCTTCTCGACCGGGCAAGCGAGGGTACCTACCGCCTCGGACCGCATATCATGCGC
TGGGCAAGCGGCTTCCTCGGCCAATCGGATCTGGTGGGAGAGTTCAGACGTGTCTTCGCCGACGTGCCGGCGCTGGAGAA
CTACACCATCACCCTGACGCGGCTCGAAGGGCCGGACGTGGTCTATCTGGCGTGCCGCAACAGCGCCGCACCGCTCGGCT
TCACCTTCCGCATCGGGATGCGCCTGCCGGCGCCATTCACCGCCACGGGAAAGGCCATGCTGAGCACTTTCTCACCGGAA
AAGGTGCGCGCCCTGCTCGCCGGACCATGGCCCGAGCGCCTCACCTCCAACAGCACGCCCTCGCTGCCGGCCCTGCTCGA
AGAGATGGAGGCGACCCGCGCCCGCGGCTATTCCATCGACGACGGCCAGATCCGGGAAGGCATGGTGTGCATCGGCATCC
CGGTGCGCGATTACACGGGCGGCACCGTGGCGGGCATCGCCATCAGCCTGCTGGAAGCCGAGGCCTCGCGGGAGCGGATG
GACGAATTGGGGGCCGGCCTGCAGCGGATCGCCTCGGCCCTGTCCACACGGCTCGGTGCCGACCGGGGCGCCTGA

Upstream 100 bases:

>100_bases
ATGCAGCACGCGGTCTCTCCCTGACGCTTCCCAAGTTCAATTAGTTGAACTATGTTCTTTGTAATGAACTATTTATCGAC
TAAGCTCGTTCGTCAAGGGT

Downstream 100 bases:

>100_bases
AAGGGAAAGGGCGCAGCGCCCGCACGCCGCGCCCTTGCTCGCATCGACCGGGGGAGTGGAAGGCCGAGGCGAGGCGGGTC
CTTGAGACGCCTGCTGCTCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MIMATDGLTSPTDSVPALRRAVRILDHVGSANAPLTAAEITRALALPKSSAHGLISALLDLGLLDRASEGTYRLGPHIMR
WASGFLGQSDLVGEFRRVFADVPALENYTITLTRLEGPDVVYLACRNSAAPLGFTFRIGMRLPAPFTATGKAMLSTFSPE
KVRALLAGPWPERLTSNSTPSLPALLEEMEATRARGYSIDDGQIREGMVCIGIPVRDYTGGTVAGIAISLLEAEASRERM
DELGAGLQRIASALSTRLGADRGA

Sequences:

>Translated_264_residues
MIMATDGLTSPTDSVPALRRAVRILDHVGSANAPLTAAEITRALALPKSSAHGLISALLDLGLLDRASEGTYRLGPHIMR
WASGFLGQSDLVGEFRRVFADVPALENYTITLTRLEGPDVVYLACRNSAAPLGFTFRIGMRLPAPFTATGKAMLSTFSPE
KVRALLAGPWPERLTSNSTPSLPALLEEMEATRARGYSIDDGQIREGMVCIGIPVRDYTGGTVAGIAISLLEAEASRERM
DELGAGLQRIASALSTRLGADRGA
>Mature_264_residues
MIMATDGLTSPTDSVPALRRAVRILDHVGSANAPLTAAEITRALALPKSSAHGLISALLDLGLLDRASEGTYRLGPHIMR
WASGFLGQSDLVGEFRRVFADVPALENYTITLTRLEGPDVVYLACRNSAAPLGFTFRIGMRLPAPFTATGKAMLSTFSPE
KVRALLAGPWPERLTSNSTPSLPALLEEMEATRARGYSIDDGQIREGMVCIGIPVRDYTGGTVAGIAISLLEAEASRERM
DELGAGLQRIASALSTRLGADRGA

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=247, Percent_Identity=27.1255060728745, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788131, Length=258, Percent_Identity=28.2945736434109, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082359, Length=258, Percent_Identity=25.1937984496124, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790752, Length=254, Percent_Identity=25.9842519685039, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786715, Length=247, Percent_Identity=23.4817813765182, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28063; Mature: 28063

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMATDGLTSPTDSVPALRRAVRILDHVGSANAPLTAAEITRALALPKSSAHGLISALLD
CEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
LGLLDRASEGTYRLGPHIMRWASGFLGQSDLVGEFRRVFADVPALENYTITLTRLEGPDV
HHHHCCCCCCCEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCE
VYLACRNSAAPLGFTFRIGMRLPAPFTATGKAMLSTFSPEKVRALLAGPWPERLTSNSTP
EEEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCHHHHCCCCCC
SLPALLEEMEATRARGYSIDDGQIREGMVCIGIPVRDYTGGTVAGIAISLLEAEASRERM
CHHHHHHHHHHHHHCCCCCCCCCHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DELGAGLQRIASALSTRLGADRGA
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIMATDGLTSPTDSVPALRRAVRILDHVGSANAPLTAAEITRALALPKSSAHGLISALLD
CEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
LGLLDRASEGTYRLGPHIMRWASGFLGQSDLVGEFRRVFADVPALENYTITLTRLEGPDV
HHHHCCCCCCCEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCE
VYLACRNSAAPLGFTFRIGMRLPAPFTATGKAMLSTFSPEKVRALLAGPWPERLTSNSTP
EEEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCHHHHCCCCCC
SLPALLEEMEATRARGYSIDDGQIREGMVCIGIPVRDYTGGTVAGIAISLLEAEASRERM
CHHHHHHHHHHHHHCCCCCCCCCHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DELGAGLQRIASALSTRLGADRGA
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]