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The map label for this gene is yiaY [H]

Identifier: 158422390

GI number: 158422390

Start: 866085

End: 867251

Strand: Direct

Name: yiaY [H]

Synonym: AZC_0766

Alternate gene names: 158422390

Gene position: 866085-867251 (Clockwise)

Preceding gene: 158422389

Following gene: 158422391

Centisome position: 16.13

GC content: 68.98

Gene sequence:

>1167_bases
ATGAGCGACGGTCTCAATCCGTTTGAATTCCGTACCGTTCCCGCCATCCAGCTCGAATGGTCCGGCGCCAAGCGCCTTGG
CGAGGTGGTGGGCGCGCGCTTTGCTGCCCGCAAGGCGCTGCTCGTCACCGATGGCGGGCTGGTGAAGGCCGGCATCATCG
CGCCCATCGTCGCCAGCCTTGAGGCGAGCGGCTTTGCCGTGACGCTGTTCGACGAAGTGGTGGCGGACCCGCCGGAGCAT
GTGCTGCTCGCCTGCGTCGCCAAGGCGAAGGCGGCGGGCGTGGATATCGTCATCGGCCTCGGCGGCGGCTCCTCGCTGGA
CGTGGCGAAGCTCGCGGCGGTACTCCTCGTCTCAGAGCAGCCGCTGGCCGATCTCTATGGCATCGGCAAGGTGCAGGGTT
CGCGCCTGCCGCTCATCCAGGTGCCCACCACCGCCGGCACGGGCTCGGAGGTGACCAACATCACCATCCTCACCACTGGC
GAGACCACCAAGATGGGCGTCGTCTCGCCCCAGCTCTATGCGGACTTCGTGCTGCTGGACGGCGAACTCACCGTGGGCCT
GCCGGCGGTGCATACGGCGGCCACGGGCATCGACGCCATGGTGCACGCCATCGAGGCTTACACCAGCCGCCACAAGAAGA
ACCCGGTCTCCGACGCTCTGGCCCGCGAGGCGCTGCGGCTTCTCTCCGCCAACCTCATCGCCGCCTGCAAGGACGGCACG
AACCGCAAGGCGCGCGAGGCCATGCTGCTGGGCGCCATGCTGGCGGGCCAGGCCTTCGCCAATTCGCCGGTGGCGGCCGT
CCACGCGCTCGCCTATCCGCTGGGCGGGCACTATCACGTGCCGCACGGCCTCTCCAATGCGCTGATGCTCGGCCCGGTGC
TGCGCTTCAACGCCAAGGCCGCCGCCCCGCTTTATGCGGAACTGGCGGACGTGATCGCCGGCCCCGGAGCGGGTGGCGCG
GAGGCGCGGGCGGATGTGTTCGTCGCCACCATGCAGAAGCTCATGGACGAGAGCGGCGCGCCCCGCCGCCTGCGCGATGT
GGGCGTGACCGACAACACCCTCGCCATGCTGGCCTCCGACGCCATGAAGCAGACGCGCCTGCTGGTGAACAATCCCGTCG
AGGTGACGGAAGCCGACGCGCTCGCGCTCTATCGCGAAGCGTTCTGA

Upstream 100 bases:

>100_bases
CGTCCCGGCCCCAGATCACCATTCCGCATTCATAAAGCGGCGGCGCGAAGCCGCCCCATCGTGCCGGTCAAGGCACGCCC
TGTGAGGAAGGAGGACCCCC

Downstream 100 bases:

>100_bases
GCATCGATGGCGCCGGCGCGCGGCGCCGGTGCCTTCTCTCCCTCTCGGACAATCGAAATCCCCCCGCATTGGCCGCGTGC
CGGTGACGGGGGACCATTGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSDGLNPFEFRTVPAIQLEWSGAKRLGEVVGARFAARKALLVTDGGLVKAGIIAPIVASLEASGFAVTLFDEVVADPPEH
VLLACVAKAKAAGVDIVIGLGGGSSLDVAKLAAVLLVSEQPLADLYGIGKVQGSRLPLIQVPTTAGTGSEVTNITILTTG
ETTKMGVVSPQLYADFVLLDGELTVGLPAVHTAATGIDAMVHAIEAYTSRHKKNPVSDALAREALRLLSANLIAACKDGT
NRKAREAMLLGAMLAGQAFANSPVAAVHALAYPLGGHYHVPHGLSNALMLGPVLRFNAKAAAPLYAELADVIAGPGAGGA
EARADVFVATMQKLMDESGAPRRLRDVGVTDNTLAMLASDAMKQTRLLVNNPVEVTEADALALYREAF

Sequences:

>Translated_388_residues
MSDGLNPFEFRTVPAIQLEWSGAKRLGEVVGARFAARKALLVTDGGLVKAGIIAPIVASLEASGFAVTLFDEVVADPPEH
VLLACVAKAKAAGVDIVIGLGGGSSLDVAKLAAVLLVSEQPLADLYGIGKVQGSRLPLIQVPTTAGTGSEVTNITILTTG
ETTKMGVVSPQLYADFVLLDGELTVGLPAVHTAATGIDAMVHAIEAYTSRHKKNPVSDALAREALRLLSANLIAACKDGT
NRKAREAMLLGAMLAGQAFANSPVAAVHALAYPLGGHYHVPHGLSNALMLGPVLRFNAKAAAPLYAELADVIAGPGAGGA
EARADVFVATMQKLMDESGAPRRLRDVGVTDNTLAMLASDAMKQTRLLVNNPVEVTEADALALYREAF
>Mature_387_residues
SDGLNPFEFRTVPAIQLEWSGAKRLGEVVGARFAARKALLVTDGGLVKAGIIAPIVASLEASGFAVTLFDEVVADPPEHV
LLACVAKAKAAGVDIVIGLGGGSSLDVAKLAAVLLVSEQPLADLYGIGKVQGSRLPLIQVPTTAGTGSEVTNITILTTGE
TTKMGVVSPQLYADFVLLDGELTVGLPAVHTAATGIDAMVHAIEAYTSRHKKNPVSDALAREALRLLSANLIAACKDGTN
RKAREAMLLGAMLAGQAFANSPVAAVHALAYPLGGHYHVPHGLSNALMLGPVLRFNAKAAAPLYAELADVIAGPGAGGAE
ARADVFVATMQKLMDESGAPRRLRDVGVTDNTLAMLASDAMKQTRLLVNNPVEVTEADALALYREAF

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=394, Percent_Identity=28.6802030456853, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI48994951, Length=362, Percent_Identity=36.1878453038674, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789163, Length=378, Percent_Identity=33.5978835978836, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87082107, Length=388, Percent_Identity=34.5360824742268, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1787493, Length=348, Percent_Identity=33.9080459770115, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789386, Length=336, Percent_Identity=27.3809523809524, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537053, Length=369, Percent_Identity=27.6422764227642, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321181, Length=355, Percent_Identity=34.3661971830986, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24657991, Length=392, Percent_Identity=29.0816326530612, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40123; Mature: 39992

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGLNPFEFRTVPAIQLEWSGAKRLGEVVGARFAARKALLVTDGGLVKAGIIAPIVASL
CCCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHCEEEEEECCCEEHHHHHHHHHHHH
EASGFAVTLFDEVVADPPEHVLLACVAKAKAAGVDIVIGLGGGSSLDVAKLAAVLLVSEQ
CCCCEEEEEEHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCC
PLADLYGIGKVQGSRLPLIQVPTTAGTGSEVTNITILTTGETTKMGVVSPQLYADFVLLD
CHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCEEECCCHHHHEEEEEEC
GELTVGLPAVHTAATGIDAMVHAIEAYTSRHKKNPVSDALAREALRLLSANLIAACKDGT
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCC
NRKAREAMLLGAMLAGQAFANSPVAAVHALAYPLGGHYHVPHGLSNALMLGPVLRFNAKA
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHCCCCC
AAPLYAELADVIAGPGAGGAEARADVFVATMQKLMDESGAPRRLRDVGVTDNTLAMLASD
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHH
AMKQTRLLVNNPVEVTEADALALYREAF
HHHHHHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SDGLNPFEFRTVPAIQLEWSGAKRLGEVVGARFAARKALLVTDGGLVKAGIIAPIVASL
CCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHCEEEEEECCCEEHHHHHHHHHHHH
EASGFAVTLFDEVVADPPEHVLLACVAKAKAAGVDIVIGLGGGSSLDVAKLAAVLLVSEQ
CCCCEEEEEEHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCC
PLADLYGIGKVQGSRLPLIQVPTTAGTGSEVTNITILTTGETTKMGVVSPQLYADFVLLD
CHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCEEECCCHHHHEEEEEEC
GELTVGLPAVHTAATGIDAMVHAIEAYTSRHKKNPVSDALAREALRLLSANLIAACKDGT
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCC
NRKAREAMLLGAMLAGQAFANSPVAAVHALAYPLGGHYHVPHGLSNALMLGPVLRFNAKA
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHCCCCC
AAPLYAELADVIAGPGAGGAEARADVFVATMQKLMDESGAPRRLRDVGVTDNTLAMLASD
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHH
AMKQTRLLVNNPVEVTEADALALYREAF
HHHHHHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]